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The map label for this gene is cobB [H]

Identifier: 193211701

GI number: 193211701

Start: 31122

End: 32480

Strand: Direct

Name: cobB [H]

Synonym: Cpar_0026

Alternate gene names: 193211701

Gene position: 31122-32480 (Clockwise)

Preceding gene: 193211700

Following gene: 193211702

Centisome position: 1.36

GC content: 63.94

Gene sequence:

>1359_bases
ATGATTTCGGCTTCTTGGAAGAGCGCCGGGAAGACCACGGTGGCGCTGGGGCTGCTGCGTCTGCTCGGGCGCGAGGGCCC
GGTGGTGAGCTTCAAGAAGGGGCCCGATTACATCGATCCGATGTGGCATCGCGTGGCCAGCGGCGGGGAGTGCTACAACC
TCGATCCGTGGATGATGGGCGCGGAGATCTGCCGCGAGTCGTTCGTCCGCGCTTCGTTGAAATATCCCGGTGGGCTGGCG
CTGATCGAGGGGAACCACGGACTGCACGACGGCCTCGACATGGCTGGTTCGGACAGCAGCGCAGGGCTGGCGGCCCTGCT
CGATACGCCGGTGGTGCTGGTAATCGACGGCCGCCGGGTCAATCGTGGCGTGGCGGCGCAGGTGCTCGGGCTGATGGCGA
TGCCACCGAAGGTGAACATCGCTGGCGTCATCTTGAACCATGTCGCCAGCGCCCGGCAAGAGGCAAAGCAGCGGGAGGCG
ATCGAGACCTATTGTAAGGTGCCGGTGCTTGGCGCGGTTCCGTCGAGCGCCTCGCTAGTGCTGCCCGAGCGGCATCTCGG
TCTCGTGACGGTTGGCGAGTCCCCGGATGCCGAGGCTTTCATCGATGCCGCCGCCGAGCAGGTCTCGAAGCATTGCGATA
TCGATGCGATCAAGGTGCTCTTCGATTCCGCGCCACCGTTCGACGCGCCGGAGCCGATCACGATCCCGACGCCAGAAACG
AGCGCAAAAGCGCGAATCGGCGTGTTCCGCGACGACGCCTTCTGTTTTTACTACCCCGACAATCTGGAGGCTCTTCGGGC
GAGCGGCGCGGAGCTAGTCTTCATCGACACCTTCAAGACCACATCGCTACCGGAGATTGACGGCCTCTATCTTGGCGGCG
GATTTCCGGAATCGTTCTTCGAGCAGTTGAGCGCGAACACCGGGCTCATGCGCGACGTGCGAGAGCGGATCGAGGCGGGG
ATGCCCGCATGGGCGGAGTGCGGCGGCCTTATCTATCTGTGCCGCAGCGCCACCTGGCAGGGGCAGACATGGCCGCTGTG
CGGCGTGCTGCCGATCGACATTGGCTACCAGCGCAAGCCCGCCGGGTGTGGCTATCTCGAACTCGAAAGCCGCGCCGGAT
CGGCGTGGTTCGGTGATGGCGAACGCATCCGCGCCCATGAATTCCACTACTCCAAGCCTGCCGAAGGCTCGCCTGAGCTG
GCCTGTCAGTTCGATGTGGCGAGGGGGTTCGGTCTGACCGGCCATGAGGACGGCATTCTCCACAAGAACCTTTTCGCCTC
CTACGCGCACCTTCACGCAGCCGCAAACCCGCACTGGGCAAAGCGCTTTGTCGAGCTTGCTGTAAGCTTCAAGTCCTAA

Upstream 100 bases:

>100_bases
GACTTTTTCACCTCGAAGGTTCGGCCTGATCAGCTGAAACCGAAGCCCTGAGCGCTTTTCCGGAGGTATCGAGTTGAGTG
CTATCACCATTCCGAGGCTG

Downstream 100 bases:

>100_bases
TCCCGGCCTAAAAAAGACTAAAAAGGTCTTGTTTTTCCCGCTGATTTTTTTATCACAAGCTCTTGTTCGATTAAAAATAT
TTTGCTAACTATATAACTAT

Product: cobyrinic acid a,c-diamide synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MISASWKSAGKTTVALGLLRLLGREGPVVSFKKGPDYIDPMWHRVASGGECYNLDPWMMGAEICRESFVRASLKYPGGLA
LIEGNHGLHDGLDMAGSDSSAGLAALLDTPVVLVIDGRRVNRGVAAQVLGLMAMPPKVNIAGVILNHVASARQEAKQREA
IETYCKVPVLGAVPSSASLVLPERHLGLVTVGESPDAEAFIDAAAEQVSKHCDIDAIKVLFDSAPPFDAPEPITIPTPET
SAKARIGVFRDDAFCFYYPDNLEALRASGAELVFIDTFKTTSLPEIDGLYLGGGFPESFFEQLSANTGLMRDVRERIEAG
MPAWAECGGLIYLCRSATWQGQTWPLCGVLPIDIGYQRKPAGCGYLELESRAGSAWFGDGERIRAHEFHYSKPAEGSPEL
ACQFDVARGFGLTGHEDGILHKNLFASYAHLHAAANPHWAKRFVELAVSFKS

Sequences:

>Translated_452_residues
MISASWKSAGKTTVALGLLRLLGREGPVVSFKKGPDYIDPMWHRVASGGECYNLDPWMMGAEICRESFVRASLKYPGGLA
LIEGNHGLHDGLDMAGSDSSAGLAALLDTPVVLVIDGRRVNRGVAAQVLGLMAMPPKVNIAGVILNHVASARQEAKQREA
IETYCKVPVLGAVPSSASLVLPERHLGLVTVGESPDAEAFIDAAAEQVSKHCDIDAIKVLFDSAPPFDAPEPITIPTPET
SAKARIGVFRDDAFCFYYPDNLEALRASGAELVFIDTFKTTSLPEIDGLYLGGGFPESFFEQLSANTGLMRDVRERIEAG
MPAWAECGGLIYLCRSATWQGQTWPLCGVLPIDIGYQRKPAGCGYLELESRAGSAWFGDGERIRAHEFHYSKPAEGSPEL
ACQFDVARGFGLTGHEDGILHKNLFASYAHLHAAANPHWAKRFVELAVSFKS
>Mature_452_residues
MISASWKSAGKTTVALGLLRLLGREGPVVSFKKGPDYIDPMWHRVASGGECYNLDPWMMGAEICRESFVRASLKYPGGLA
LIEGNHGLHDGLDMAGSDSSAGLAALLDTPVVLVIDGRRVNRGVAAQVLGLMAMPPKVNIAGVILNHVASARQEAKQREA
IETYCKVPVLGAVPSSASLVLPERHLGLVTVGESPDAEAFIDAAAEQVSKHCDIDAIKVLFDSAPPFDAPEPITIPTPET
SAKARIGVFRDDAFCFYYPDNLEALRASGAELVFIDTFKTTSLPEIDGLYLGGGFPESFFEQLSANTGLMRDVRERIEAG
MPAWAECGGLIYLCRSATWQGQTWPLCGVLPIDIGYQRKPAGCGYLELESRAGSAWFGDGERIRAHEFHYSKPAEGSPEL
ACQFDVARGFGLTGHEDGILHKNLFASYAHLHAAANPHWAKRFVELAVSFKS

Specific function: Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation [H]

COG id: COG1797

COG function: function code H; Cobyrinic acid a,c-diamide synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GATase cobBQ-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR004484
- InterPro:   IPR017929
- InterPro:   IPR011698 [H]

Pfam domain/function: PF01656 CbiA; PF07685 GATase_3 [H]

EC number: NA

Molecular weight: Translated: 48745; Mature: 48745

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISASWKSAGKTTVALGLLRLLGREGPVVSFKKGPDYIDPMWHRVASGGECYNLDPWMMG
CCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHCCCCCEECCCHHHHH
AEICRESFVRASLKYPGGLALIEGNHGLHDGLDMAGSDSSAGLAALLDTPVVLVIDGRRV
HHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCEEECCCEEEEECCCCC
NRGVAAQVLGLMAMPPKVNIAGVILNHVASARQEAKQREAIETYCKVPVLGAVPSSASLV
CCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCEEE
LPERHLGLVTVGESPDAEAFIDAAAEQVSKHCDIDAIKVLFDSAPPFDAPEPITIPTPET
ECCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCEECCCCCC
SAKARIGVFRDDAFCFYYPDNLEALRASGAELVFIDTFKTTSLPEIDGLYLGGGFPESFF
CCCEEEEEEECCEEEEECCCCHHHHHCCCCEEEEEEECCCCCCCCCCCEEECCCCCHHHH
EQLSANTGLMRDVRERIEAGMPAWAECGGLIYLCRSATWQGQTWPLCGVLPIDIGYQRKP
HHHHCCCCHHHHHHHHHHCCCCCHHHCCCEEEEEECCCCCCCCCCEEEEEEECCCCCCCC
AGCGYLELESRAGSAWFGDGERIRAHEFHYSKPAEGSPELACQFDVARGFGLTGHEDGIL
CCCCEEEEECCCCCCEECCCCEEEEEECCCCCCCCCCCCEEEEEEHHCCCCCCCCCCCCH
HKNLFASYAHLHAAANPHWAKRFVELAVSFKS
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MISASWKSAGKTTVALGLLRLLGREGPVVSFKKGPDYIDPMWHRVASGGECYNLDPWMMG
CCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHCCCCCEECCCHHHHH
AEICRESFVRASLKYPGGLALIEGNHGLHDGLDMAGSDSSAGLAALLDTPVVLVIDGRRV
HHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCEEECCCEEEEECCCCC
NRGVAAQVLGLMAMPPKVNIAGVILNHVASARQEAKQREAIETYCKVPVLGAVPSSASLV
CCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCEEE
LPERHLGLVTVGESPDAEAFIDAAAEQVSKHCDIDAIKVLFDSAPPFDAPEPITIPTPET
ECCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCEECCCCCC
SAKARIGVFRDDAFCFYYPDNLEALRASGAELVFIDTFKTTSLPEIDGLYLGGGFPESFF
CCCEEEEEEECCEEEEECCCCHHHHHCCCCEEEEEEECCCCCCCCCCCEEECCCCCHHHH
EQLSANTGLMRDVRERIEAGMPAWAECGGLIYLCRSATWQGQTWPLCGVLPIDIGYQRKP
HHHHCCCCHHHHHHHHHHCCCCCHHHCCCEEEEEECCCCCCCCCCEEEEEEECCCCCCCC
AGCGYLELESRAGSAWFGDGERIRAHEFHYSKPAEGSPELACQFDVARGFGLTGHEDGIL
CCCCEEEEECCCCCCEECCCCEEEEEECCCCCCCCCCCCEEEEEEHHCCCCCCCCCCCCH
HKNLFASYAHLHAAANPHWAKRFVELAVSFKS
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA