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The map label for this gene is moeZ [H]

Identifier: 193214433

GI number: 193214433

Start: 841913

End: 843376

Strand: Direct

Name: moeZ [H]

Synonym: Ctha_0716

Alternate gene names: 193214433

Gene position: 841913-843376 (Clockwise)

Preceding gene: 193214432

Following gene: 193214434

Centisome position: 25.56

GC content: 48.02

Gene sequence:

>1464_bases
ATGGGAACGAAAATCTTGATACCCACAGCGCTCAGGCAATATGCGGGTGGACATGACGTTGTTGAGGTAAGTGCTGGAGA
TGTCGCAAAAGCCTTAGCTGAATTGACGAGTTTATATCCGGCGCTCAAGAAAAATTTGTTTGCTGAAAATGGCAAACTGC
GTTCTTTTATCAATGTGTATAAAGGCGAAGAGAACATTAAAAACCTCAATCAGCTCGAAACAACTATTGAGGAAGGCGAT
GAGCTTTTAATTGTTCCCTCCATTGCGGGGGGCGCGCCCGCCGACTTGGAAGTGCTTCACGAACTTTCTAATGAAGAAAT
CCAGCGATATAGCCGGCATTTGCTCGTTCCTGAATTTGGCATGGAAGGGCAAAAAAAACTCAAACAGGCCAGCGTGCTGA
TGATCGGCGCGGGCGGCCTGGGTTCGCCGCTCGGCATGTATTTGGCCGCTGCTGGCGTGGGCAAGCTTGGCATTGTGGAA
TATGACACGGTGGATTACTCCAACTTGCAGCGCCAACTTTTATACAAAACCGCTGATGTCGGGCGATCAAAAGCTGAAGC
TGCTCGCGATACCATTAAAAGCATCAATCCATTTGTTGAAGTTGAAATTCATCAGGTCCCGCTAACTTCCCTCAACGCAC
TTGACATCCTGAAACACTACGATGTGGTGGCCGACGGCACGGATAATTTTCCCACGCGCTATTTGGTGAACGATGCTTGT
GTGATGCTCGGCAAGCCAAATGTGTATGGAAGCATTTTCCGTTTTGAAGGCCAAGTCAGCGTGTTTCATTTAAATGACGA
CACCGCTTGCTACCGCTGCTTATATCCCGAACCGCCACCGCCAGGACTTGTTCCTTCTTGCGCTCAAAGCGGCGTTCTTG
GCGTTTTACCTGGCATTATCGGTTCGTTGCAAGCCATTGAAGTCATTAAAATCATTACAGGAATTGGTGAGCCGCTCGCC
AACCGCCTGATCACATTTGATGCGCTGAAAATGAAATTCCGCGAGCTTAAGCTCAAAAAAGATCCAGAATGTTTGCTTTG
CTCGGAGCATCCGGCCATTACGGAACTTATCGACTATGAACAATTTTGCGGCATGCCCGCACACGACCGAATAGAGAAAA
AACCGCTCGCAAAGGTTTCAACCGATCCCAATGAAATTACCGTGCACGAGCTGAAATCCCGTTTCGATCGCGGCGAAAAA
CCGTTTATTTTGGATGTGCGCAACCCGACGGAAACTCAAATTTGCTGTTTGGAAGAAACAACCCTGATTCCATTAAATGA
ACTTCCCGCGCGCTTGCACGAGCTTGATGCCCAATTGGAAATTATCGCGCTCTGTAGAAGTGGCGCGCGCTCGGATAACG
CTGCGGAATTTTTGCGCAAAAACGGATTTAAAAACGTGAAAAATCTTGTTGGCGGGATTTTGGCATGGAGCAAAGAAATC
GACCCAACCATGCCAACTTATTAG

Upstream 100 bases:

>100_bases
TTAGCAAGGAATAGACTTTATGCTGAAGTTCGTTTTTGCAAAGTTGAAGCAAAAACGAAGCTTGAGGAATTTTTCTCAAT
CAATAAAAAGAGTTGACGCA

Downstream 100 bases:

>100_bases
AAAATATGAACTTTTTCACGCCGTCGTTTCAAAAAAAGCAGCTTTTGTAGCTGCTTTTTTGTTACAACCATCGCGGATTT
CGTTTTTTCAGAAGCGGCTC

Product: UBA/THIF-type NAD/FAD binding protein

Products: NA

Alternate protein names: Sulfur carrier protein CysO adenylyltransferase; Sulfur carrier protein CysO sulfurtransferase [H]

Number of amino acids: Translated: 487; Mature: 486

Protein sequence:

>487_residues
MGTKILIPTALRQYAGGHDVVEVSAGDVAKALAELTSLYPALKKNLFAENGKLRSFINVYKGEENIKNLNQLETTIEEGD
ELLIVPSIAGGAPADLEVLHELSNEEIQRYSRHLLVPEFGMEGQKKLKQASVLMIGAGGLGSPLGMYLAAAGVGKLGIVE
YDTVDYSNLQRQLLYKTADVGRSKAEAARDTIKSINPFVEVEIHQVPLTSLNALDILKHYDVVADGTDNFPTRYLVNDAC
VMLGKPNVYGSIFRFEGQVSVFHLNDDTACYRCLYPEPPPPGLVPSCAQSGVLGVLPGIIGSLQAIEVIKIITGIGEPLA
NRLITFDALKMKFRELKLKKDPECLLCSEHPAITELIDYEQFCGMPAHDRIEKKPLAKVSTDPNEITVHELKSRFDRGEK
PFILDVRNPTETQICCLEETTLIPLNELPARLHELDAQLEIIALCRSGARSDNAAEFLRKNGFKNVKNLVGGILAWSKEI
DPTMPTY

Sequences:

>Translated_487_residues
MGTKILIPTALRQYAGGHDVVEVSAGDVAKALAELTSLYPALKKNLFAENGKLRSFINVYKGEENIKNLNQLETTIEEGD
ELLIVPSIAGGAPADLEVLHELSNEEIQRYSRHLLVPEFGMEGQKKLKQASVLMIGAGGLGSPLGMYLAAAGVGKLGIVE
YDTVDYSNLQRQLLYKTADVGRSKAEAARDTIKSINPFVEVEIHQVPLTSLNALDILKHYDVVADGTDNFPTRYLVNDAC
VMLGKPNVYGSIFRFEGQVSVFHLNDDTACYRCLYPEPPPPGLVPSCAQSGVLGVLPGIIGSLQAIEVIKIITGIGEPLA
NRLITFDALKMKFRELKLKKDPECLLCSEHPAITELIDYEQFCGMPAHDRIEKKPLAKVSTDPNEITVHELKSRFDRGEK
PFILDVRNPTETQICCLEETTLIPLNELPARLHELDAQLEIIALCRSGARSDNAAEFLRKNGFKNVKNLVGGILAWSKEI
DPTMPTY
>Mature_486_residues
GTKILIPTALRQYAGGHDVVEVSAGDVAKALAELTSLYPALKKNLFAENGKLRSFINVYKGEENIKNLNQLETTIEEGDE
LLIVPSIAGGAPADLEVLHELSNEEIQRYSRHLLVPEFGMEGQKKLKQASVLMIGAGGLGSPLGMYLAAAGVGKLGIVEY
DTVDYSNLQRQLLYKTADVGRSKAEAARDTIKSINPFVEVEIHQVPLTSLNALDILKHYDVVADGTDNFPTRYLVNDACV
MLGKPNVYGSIFRFEGQVSVFHLNDDTACYRCLYPEPPPPGLVPSCAQSGVLGVLPGIIGSLQAIEVIKIITGIGEPLAN
RLITFDALKMKFRELKLKKDPECLLCSEHPAITELIDYEQFCGMPAHDRIEKKPLAKVSTDPNEITVHELKSRFDRGEKP
FILDVRNPTETQICCLEETTLIPLNELPARLHELDAQLEIIALCRSGARSDNAAEFLRKNGFKNVKNLVGGILAWSKEID
PTMPTY

Specific function: Catalyzes the conversion of the sulfur carrier protein CysO to CysO-thiocarboxylate. The reaction is thought to proceed in two steps:first, ATP-dependent activation of CysO as acyl- adenylate (CysO-COOAMP), followed by sulfur transfer to give CysO- thioca

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=411, Percent_Identity=42.5790754257908, Blast_Score=300, Evalue=3e-81,
Organism=Homo sapiens, GI4885649, Length=148, Percent_Identity=31.0810810810811, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI23510338, Length=179, Percent_Identity=31.2849162011173, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI23510340, Length=179, Percent_Identity=31.2849162011173, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI38045942, Length=177, Percent_Identity=30.5084745762712, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI38045944, Length=177, Percent_Identity=30.5084745762712, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI38045948, Length=167, Percent_Identity=31.7365269461078, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI13376212, Length=315, Percent_Identity=25.3968253968254, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI38327032, Length=223, Percent_Identity=25.5605381165919, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI225543285, Length=102, Percent_Identity=34.3137254901961, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI4885585, Length=102, Percent_Identity=34.3137254901961, Blast_Score=70, Evalue=6e-12,
Organism=Homo sapiens, GI225543288, Length=102, Percent_Identity=34.3137254901961, Blast_Score=69, Evalue=7e-12,
Organism=Escherichia coli, GI1787048, Length=251, Percent_Identity=40.2390438247012, Blast_Score=206, Evalue=4e-54,
Organism=Escherichia coli, GI87082356, Length=246, Percent_Identity=39.0243902439024, Blast_Score=170, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17540406, Length=397, Percent_Identity=41.5617128463476, Blast_Score=316, Evalue=2e-86,
Organism=Caenorhabditis elegans, GI193203301, Length=167, Percent_Identity=32.9341317365269, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71984476, Length=188, Percent_Identity=30.8510638297872, Blast_Score=82, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17508819, Length=266, Percent_Identity=27.4436090225564, Blast_Score=76, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6321903, Length=410, Percent_Identity=37.8048780487805, Blast_Score=249, Evalue=6e-67,
Organism=Saccharomyces cerevisiae, GI6320598, Length=172, Percent_Identity=29.6511627906977, Blast_Score=78, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6322639, Length=193, Percent_Identity=27.979274611399, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24582879, Length=436, Percent_Identity=43.348623853211, Blast_Score=345, Evalue=3e-95,
Organism=Drosophila melanogaster, GI24660640, Length=151, Percent_Identity=33.112582781457, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI20129973, Length=173, Percent_Identity=30.635838150289, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28573937, Length=187, Percent_Identity=28.3422459893048, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24641311, Length=229, Percent_Identity=28.3842794759825, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR001763
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00581 Rhodanese; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 53521; Mature: 53390

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTKILIPTALRQYAGGHDVVEVSAGDVAKALAELTSLYPALKKNLFAENGKLRSFINVY
CCCEEECHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
KGEENIKNLNQLETTIEEGDELLIVPSIAGGAPADLEVLHELSNEEIQRYSRHLLVPEFG
CCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHCHHHHHHHHHHCCCCCCC
MEGQKKLKQASVLMIGAGGLGSPLGMYLAAAGVGKLGIVEYDTVDYSNLQRQLLYKTADV
CCHHHHHHHCCEEEEECCCCCCHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHC
GRSKAEAARDTIKSINPFVEVEIHQVPLTSLNALDILKHYDVVADGTDNFPTRYLVNDAC
CCHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHCEEECCCCCCCCEEEECCEE
VMLGKPNVYGSIFRFEGQVSVFHLNDDTACYRCLYPEPPPPGLVPSCAQSGVLGVLPGII
EEECCCCCCEEEEEEECEEEEEEECCCCEEEEEECCCCCCCCCCCHHHHCCHHHHHHHHH
GSLQAIEVIKIITGIGEPLANRLITFDALKMKFRELKLKKDPECLLCSEHPAITELIDYE
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHCHH
QFCGMPAHDRIEKKPLAKVSTDPNEITVHELKSRFDRGEKPFILDVRNPTETQICCLEET
HHCCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEECCCCCCCEEEEECCC
TLIPLNELPARLHELDAQLEIIALCRSGARSDNAAEFLRKNGFKNVKNLVGGILAWSKEI
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCC
DPTMPTY
CCCCCCC
>Mature Secondary Structure 
GTKILIPTALRQYAGGHDVVEVSAGDVAKALAELTSLYPALKKNLFAENGKLRSFINVY
CCEEECHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
KGEENIKNLNQLETTIEEGDELLIVPSIAGGAPADLEVLHELSNEEIQRYSRHLLVPEFG
CCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHCHHHHHHHHHHCCCCCCC
MEGQKKLKQASVLMIGAGGLGSPLGMYLAAAGVGKLGIVEYDTVDYSNLQRQLLYKTADV
CCHHHHHHHCCEEEEECCCCCCHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHC
GRSKAEAARDTIKSINPFVEVEIHQVPLTSLNALDILKHYDVVADGTDNFPTRYLVNDAC
CCHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHCEEECCCCCCCCEEEECCEE
VMLGKPNVYGSIFRFEGQVSVFHLNDDTACYRCLYPEPPPPGLVPSCAQSGVLGVLPGII
EEECCCCCCEEEEEEECEEEEEEECCCCEEEEEECCCCCCCCCCCHHHHCCHHHHHHHHH
GSLQAIEVIKIITGIGEPLANRLITFDALKMKFRELKLKKDPECLLCSEHPAITELIDYE
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHCHH
QFCGMPAHDRIEKKPLAKVSTDPNEITVHELKSRFDRGEKPFILDVRNPTETQICCLEET
HHCCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEECCCCCCCEEEEECCC
TLIPLNELPARLHELDAQLEIIALCRSGARSDNAAEFLRKNGFKNVKNLVGGILAWSKEI
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCC
DPTMPTY
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]