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The map label for this gene is siaT [H]

Identifier: 192291190

GI number: 192291190

Start: 3056066

End: 3057424

Strand: Reverse

Name: siaT [H]

Synonym: Rpal_2811

Alternate gene names: 192291190

Gene position: 3057424-3056066 (Counterclockwise)

Preceding gene: 192291191

Following gene: 192291185

Centisome position: 53.23

GC content: 66.15

Gene sequence:

>1359_bases
GTGACAGTCCTCGGCATTGGGATCAGTTACGGCCTCGCCACGCTGGCGGCGATGTTCTCCGGCATGCCGATCGCATTTGC
GCTCGGCGCCGTCGCGCTGGTGTTCATGGCGATCTACATGCCGCACGCCTCGCTCGATACCGTGACGCAGAACGTCTACG
AGGAGATGGCGTCGATCACGCTGCTGTCGATCCCGCTGTTCATCCTCAAGGGTGCCGCGATCGGCAAGTCCCGTGCCGGC
CAGGACCTGTACTCCGCCCTGCACGCCTGGCTGCATCGCGTGCCGGGCGGGCTCGGCGTCGCCAACGTGTTCGCCTGCGC
GCTGTTCGCCGCGATGGCCGGCTCGTCGCCGGCAACGTGTTCGGCGATCGGCTCGGCCGGCATCCCGGAGATGCGCAAGC
GCGGCTATTCCGGCGGCTTCGCAGCCGGGATTATCGCGGCCGGCGGCACGCTCGGCATCCTGCTGCCGCCCTCGATCACC
ATGATCCTGTTCGCGGTCGCCGCCGAAAAATCGCTCGGCCGGCTGTTCCTCGCCGGCATCGGGCCGGGATTGCTGCTGGT
GACGCTGTTCGGCATCTACGCGGTGATCCGCTTCCGCAAGGAATACGCCACCGCAAAGGCGGCGTACGAAGCGACCGGCC
AGACGTCCGCAATCCTGACCGACGAGAAATTCACCATGGCGCAGCGCTTCGGCGCGCTGCCGCGGGTGCTGCCGTTCGTC
ATCTTGCTCACCGGCGTGATGATCGCGCTGTATGGCGGCTACGCGACGCCGTCCGAAACCGCCGGCCTCGGCGGCCTGCT
GGCGCTGCTGCTGATCGCGCTGATCTACGGGGTGTGGAAGCCATCCGACCTGTCGCCGATCATGACCTCGACGGTCCGCG
AGTCGACCATGCTGATGATGATCATCGGCATGTCGCTGCTGTACTCCTACGTGATGAGCTATCTGCACATCTCGCAGTCG
GCCGCCGAAGCGATCGTGGCAATGCAGCTGCCGCGCTGGGGCCTGCTCGCCGCGATCCTGGCGCTGGTGGTGGTGCTCGG
CTTTTTCCTGCCGCCGGTGTCGATCATCCTGATGACCGCGCCGATCATCCTGCCGCCGCTGCGCGCGGCCGGCTTCGACA
TTATCTGGTTCGGCGTGGTGATGACCATCGTGATGGAGATGGGCCTGATCCACCCGCCGGTCGGCCTCAACATCTTCGTC
ATCCGCAACGTCGCCCCCGATATCCCGCTCTCCGAGGTGATCTGGGGCACGCTGCCGTTCGTACTGCTGATGATGTTCGC
AGTGCTGCTGCTGTGCCTGGTCCCCGGCATCTCGACCTGGCTGCCGGATCTGGTGATGGGGCCGGAGAGCGTCAGATAG

Upstream 100 bases:

>100_bases
CGCTCGCCATCCCCTACGCGCTGATGGCCGCCGGCATGACGCTGCTGTGCCTGCAGATCGCGGTGCAGATCGTGAACTCC
TTCAGTGGGACGAAGCGCGC

Downstream 100 bases:

>100_bases
TTCGCGAGGGGTAGGCGCACTTGCGCCGTAACCACCCTCTCTGTGTTGACACCTCGATCGGTGGGTTACGCGCTTCGCGC
TAACAAACCCTACGAACTAA

Product: TRAP dicarboxylate transporter subunit DctM

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MTVLGIGISYGLATLAAMFSGMPIAFALGAVALVFMAIYMPHASLDTVTQNVYEEMASITLLSIPLFILKGAAIGKSRAG
QDLYSALHAWLHRVPGGLGVANVFACALFAAMAGSSPATCSAIGSAGIPEMRKRGYSGGFAAGIIAAGGTLGILLPPSIT
MILFAVAAEKSLGRLFLAGIGPGLLLVTLFGIYAVIRFRKEYATAKAAYEATGQTSAILTDEKFTMAQRFGALPRVLPFV
ILLTGVMIALYGGYATPSETAGLGGLLALLLIALIYGVWKPSDLSPIMTSTVRESTMLMMIIGMSLLYSYVMSYLHISQS
AAEAIVAMQLPRWGLLAAILALVVVLGFFLPPVSIILMTAPIILPPLRAAGFDIIWFGVVMTIVMEMGLIHPPVGLNIFV
IRNVAPDIPLSEVIWGTLPFVLLMMFAVLLLCLVPGISTWLPDLVMGPESVR

Sequences:

>Translated_452_residues
MTVLGIGISYGLATLAAMFSGMPIAFALGAVALVFMAIYMPHASLDTVTQNVYEEMASITLLSIPLFILKGAAIGKSRAG
QDLYSALHAWLHRVPGGLGVANVFACALFAAMAGSSPATCSAIGSAGIPEMRKRGYSGGFAAGIIAAGGTLGILLPPSIT
MILFAVAAEKSLGRLFLAGIGPGLLLVTLFGIYAVIRFRKEYATAKAAYEATGQTSAILTDEKFTMAQRFGALPRVLPFV
ILLTGVMIALYGGYATPSETAGLGGLLALLLIALIYGVWKPSDLSPIMTSTVRESTMLMMIIGMSLLYSYVMSYLHISQS
AAEAIVAMQLPRWGLLAAILALVVVLGFFLPPVSIILMTAPIILPPLRAAGFDIIWFGVVMTIVMEMGLIHPPVGLNIFV
IRNVAPDIPLSEVIWGTLPFVLLMMFAVLLLCLVPGISTWLPDLVMGPESVR
>Mature_451_residues
TVLGIGISYGLATLAAMFSGMPIAFALGAVALVFMAIYMPHASLDTVTQNVYEEMASITLLSIPLFILKGAAIGKSRAGQ
DLYSALHAWLHRVPGGLGVANVFACALFAAMAGSSPATCSAIGSAGIPEMRKRGYSGGFAAGIIAAGGTLGILLPPSITM
ILFAVAAEKSLGRLFLAGIGPGLLLVTLFGIYAVIRFRKEYATAKAAYEATGQTSAILTDEKFTMAQRFGALPRVLPFVI
LLTGVMIALYGGYATPSETAGLGGLLALLLIALIYGVWKPSDLSPIMTSTVRESTMLMMIIGMSLLYSYVMSYLHISQSA
AEAIVAMQLPRWGLLAAILALVVVLGFFLPPVSIILMTAPIILPPLRAAGFDIIWFGVVMTIVMEMGLIHPPVGLNIFVI
RNVAPDIPLSEVIWGTLPFVLLMMFAVLLLCLVPGISTWLPDLVMGPESVR

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=405, Percent_Identity=26.4197530864197, Blast_Score=101, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 47660; Mature: 47529

Theoretical pI: Translated: 8.41; Mature: 8.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVLGIGISYGLATLAAMFSGMPIAFALGAVALVFMAIYMPHASLDTVTQNVYEEMASIT
CEEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
LLSIPLFILKGAAIGKSRAGQDLYSALHAWLHRVPGGLGVANVFACALFAAMAGSSPATC
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHH
SAIGSAGIPEMRKRGYSGGFAAGIIAAGGTLGILLPPSITMILFAVAAEKSLGRLFLAGI
HHHCCCCCCHHHHCCCCCCHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHC
GPGLLLVTLFGIYAVIRFRKEYATAKAAYEATGQTSAILTDEKFTMAQRFGALPRVLPFV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHCCCHHHHHHH
ILLTGVMIALYGGYATPSETAGLGGLLALLLIALIYGVWKPSDLSPIMTSTVRESTMLMM
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
IIGMSLLYSYVMSYLHISQSAAEAIVAMQLPRWGLLAAILALVVVLGFFLPPVSIILMTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PIILPPLRAAGFDIIWFGVVMTIVMEMGLIHPPVGLNIFVIRNVAPDIPLSEVIWGTLPF
HHHHCCHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHH
VLLMMFAVLLLCLVPGISTWLPDLVMGPESVR
HHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TVLGIGISYGLATLAAMFSGMPIAFALGAVALVFMAIYMPHASLDTVTQNVYEEMASIT
EEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
LLSIPLFILKGAAIGKSRAGQDLYSALHAWLHRVPGGLGVANVFACALFAAMAGSSPATC
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHH
SAIGSAGIPEMRKRGYSGGFAAGIIAAGGTLGILLPPSITMILFAVAAEKSLGRLFLAGI
HHHCCCCCCHHHHCCCCCCHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHC
GPGLLLVTLFGIYAVIRFRKEYATAKAAYEATGQTSAILTDEKFTMAQRFGALPRVLPFV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHCCCHHHHHHH
ILLTGVMIALYGGYATPSETAGLGGLLALLLIALIYGVWKPSDLSPIMTSTVRESTMLMM
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
IIGMSLLYSYVMSYLHISQSAAEAIVAMQLPRWGLLAAILALVVVLGFFLPPVSIILMTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PIILPPLRAAGFDIIWFGVVMTIVMEMGLIHPPVGLNIFVIRNVAPDIPLSEVIWGTLPF
HHHHCCHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHH
VLLMMFAVLLLCLVPGISTWLPDLVMGPESVR
HHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]