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The map label for this gene is baeS [H]

Identifier: 192290994

GI number: 192290994

Start: 2823540

End: 2824643

Strand: Reverse

Name: baeS [H]

Synonym: Rpal_2611

Alternate gene names: 192290994

Gene position: 2824643-2823540 (Counterclockwise)

Preceding gene: 192290995

Following gene: 192290992

Centisome position: 49.18

GC content: 64.13

Gene sequence:

>1104_bases
ATGAGACGTCATCGCCTCAGCAGGCAGATCACACTGTCGATGAGCGTCGTCGTCGCCATCGCGGTGCTGATGGTGTTCGT
CGGCACGTTCATCTTCTACAGCATCTATATGACCTGGTTCCCGCCGCCGCCGGGTCCGCCCCCGCTGCTGCCGGAAGCAC
CCGACTTCATCCTGATCGCGATCTTCCTTCTGCTCGGCCTCGCCATCGCGATCCACGCCGCGCTTCGGCTGACGCGGCGC
ATCCTTGCACCACTCAATTCGCTGGCCGAAGGCGCTCGCAAGATCGCAGCTGGCGACCTCACCGCACGCGCGGTCGCCGG
CGATCGCTCACTCGGCGAAACGGCGCAACTCGTCGACGATTTCAACGCGATGGCTCGGCGTCTGGAAGACGCGGCGGAAT
CGATGACCTCGTGGAATGCTGCCATCGCGCATGAACTGCGCACACCGCTGACAATTCTGCGCGGCCGCCTGCAAGGCCTC
ACCGACGGCGTCTTCGAACCCAGCGACGAGCTGTTCAGGAGCCTGTTGGTTCAGGTCGAAAACCTGTCGCGTCTCGTCGA
CGATCTGCGGGTCGTGACCCTGTCGGACAGCCAGCGCCTCGACATGCGTGTCGAACCGACGGATCTCGCCAACGAGGTGG
CGCAGGCCGTCGATGCGATGCGCCCTGCCCTCGAAGGAGCCGGCTTTTCTATTCGGATGACAACCGAGCCGGTGACGCTG
CCATGCGACGGCCCGCGGATCCGACAGGCCCTACTCGCGCTTTTGGAAAACGCGCGCCGCTACGCAACGCCCGGCATGAT
CGTGATCCGGATGACTCTGGAGACGTTCGAGGTGGCCATCGCCGTTGAAGACGAGGGTCCCGGCTTGAGCGCCGAGTTCG
CGGCACGAGCATTCGATGCTTTCGTACGGGCCGAGCCTTCCCGGTCCCGGCAATTCGGCGGCTCGGGCCTCGGATTGTCG
GTAGTGCGTGCGATCGCCGAGGCGCATGGCGGACACGCCCGATACAGCACTTCGGAAAAAGGCGGCTCTGTATTCGAGAT
CGTTTTTCCCATCGACGGCGCCTCTGCCGACTCCAATGCTGCATCTTGCGCGCCGAAGGTCTGA

Upstream 100 bases:

>100_bases
TCGACAGCCATGTCAGCAATCTGCGCCGCAAGCTCGACGAGGCGGGCGCGACCGGGATGATGTCGGTCGTGCGCGGGATC
GGCTACCGGCTAACGGCCGC

Downstream 100 bases:

>100_bases
CGACTGCGTGACTACGCGTCCAACCGTCACAGCTGTAAATCGAAAGTCGCGCACCAAATGTCGAACCTGTCCCATTCGGG
GACCGATGACGTCCGCTTAT

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MRRHRLSRQITLSMSVVVAIAVLMVFVGTFIFYSIYMTWFPPPPGPPPLLPEAPDFILIAIFLLLGLAIAIHAALRLTRR
ILAPLNSLAEGARKIAAGDLTARAVAGDRSLGETAQLVDDFNAMARRLEDAAESMTSWNAAIAHELRTPLTILRGRLQGL
TDGVFEPSDELFRSLLVQVENLSRLVDDLRVVTLSDSQRLDMRVEPTDLANEVAQAVDAMRPALEGAGFSIRMTTEPVTL
PCDGPRIRQALLALLENARRYATPGMIVIRMTLETFEVAIAVEDEGPGLSAEFAARAFDAFVRAEPSRSRQFGGSGLGLS
VVRAIAEAHGGHARYSTSEKGGSVFEIVFPIDGASADSNAASCAPKV

Sequences:

>Translated_367_residues
MRRHRLSRQITLSMSVVVAIAVLMVFVGTFIFYSIYMTWFPPPPGPPPLLPEAPDFILIAIFLLLGLAIAIHAALRLTRR
ILAPLNSLAEGARKIAAGDLTARAVAGDRSLGETAQLVDDFNAMARRLEDAAESMTSWNAAIAHELRTPLTILRGRLQGL
TDGVFEPSDELFRSLLVQVENLSRLVDDLRVVTLSDSQRLDMRVEPTDLANEVAQAVDAMRPALEGAGFSIRMTTEPVTL
PCDGPRIRQALLALLENARRYATPGMIVIRMTLETFEVAIAVEDEGPGLSAEFAARAFDAFVRAEPSRSRQFGGSGLGLS
VVRAIAEAHGGHARYSTSEKGGSVFEIVFPIDGASADSNAASCAPKV
>Mature_367_residues
MRRHRLSRQITLSMSVVVAIAVLMVFVGTFIFYSIYMTWFPPPPGPPPLLPEAPDFILIAIFLLLGLAIAIHAALRLTRR
ILAPLNSLAEGARKIAAGDLTARAVAGDRSLGETAQLVDDFNAMARRLEDAAESMTSWNAAIAHELRTPLTILRGRLQGL
TDGVFEPSDELFRSLLVQVENLSRLVDDLRVVTLSDSQRLDMRVEPTDLANEVAQAVDAMRPALEGAGFSIRMTTEPVTL
PCDGPRIRQALLALLENARRYATPGMIVIRMTLETFEVAIAVEDEGPGLSAEFAARAFDAFVRAEPSRSRQFGGSGLGLS
VVRAIAEAHGGHARYSTSEKGGSVFEIVFPIDGASADSNAASCAPKV

Specific function: Member of the two-component regulatory system BaeS/BaeR. May activate BaeR by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=276, Percent_Identity=35.5072463768116, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1786783, Length=296, Percent_Identity=30.4054054054054, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1787894, Length=308, Percent_Identity=28.2467532467532, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1786912, Length=217, Percent_Identity=33.6405529953917, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1786600, Length=222, Percent_Identity=29.2792792792793, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI1789808, Length=302, Percent_Identity=27.1523178807947, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1790346, Length=237, Percent_Identity=31.6455696202532, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI145693157, Length=246, Percent_Identity=27.2357723577236, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI87081816, Length=244, Percent_Identity=28.6885245901639, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI48994928, Length=227, Percent_Identity=26.431718061674, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789149, Length=352, Percent_Identity=23.5795454545455, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1788279, Length=234, Percent_Identity=27.7777777777778, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790551, Length=353, Percent_Identity=26.0623229461756, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789403, Length=287, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788549, Length=235, Percent_Identity=27.2340425531915, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1790436, Length=224, Percent_Identity=26.3392857142857, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 39604; Mature: 39604

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRHRLSRQITLSMSVVVAIAVLMVFVGTFIFYSIYMTWFPPPPGPPPLLPEAPDFILIA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHH
IFLLLGLAIAIHAALRLTRRILAPLNSLAEGARKIAAGDLTARAVAGDRSLGETAQLVDD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHHH
FNAMARRLEDAAESMTSWNAAIAHELRTPLTILRGRLQGLTDGVFEPSDELFRSLLVQVE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
NLSRLVDDLRVVTLSDSQRLDMRVEPTDLANEVAQAVDAMRPALEGAGFSIRMTTEPVTL
HHHHHHHHHEEEEECCCCCCCEEECCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEE
PCDGPRIRQALLALLENARRYATPGMIVIRMTLETFEVAIAVEDEGPGLSAEFAARAFDA
CCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEEEEEEECCCCCCCHHHHHHHHHH
FVRAEPSRSRQFGGSGLGLSVVRAIAEAHGGHARYSTSEKGGSVFEIVFPIDGASADSNA
HHHCCCCHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCC
ASCAPKV
CCCCCCC
>Mature Secondary Structure
MRRHRLSRQITLSMSVVVAIAVLMVFVGTFIFYSIYMTWFPPPPGPPPLLPEAPDFILIA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHH
IFLLLGLAIAIHAALRLTRRILAPLNSLAEGARKIAAGDLTARAVAGDRSLGETAQLVDD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHHH
FNAMARRLEDAAESMTSWNAAIAHELRTPLTILRGRLQGLTDGVFEPSDELFRSLLVQVE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
NLSRLVDDLRVVTLSDSQRLDMRVEPTDLANEVAQAVDAMRPALEGAGFSIRMTTEPVTL
HHHHHHHHHEEEEECCCCCCCEEECCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEE
PCDGPRIRQALLALLENARRYATPGMIVIRMTLETFEVAIAVEDEGPGLSAEFAARAFDA
CCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEEEEEEECCCCCCCHHHHHHHHHH
FVRAEPSRSRQFGGSGLGLSVVRAIAEAHGGHARYSTSEKGGSVFEIVFPIDGASADSNA
HHHCCCCHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCC
ASCAPKV
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8282725; 9097040; 9278503 [H]