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The map label for this gene is ddpA [H]

Identifier: 192290058

GI number: 192290058

Start: 1779123

End: 1780742

Strand: Reverse

Name: ddpA [H]

Synonym: Rpal_1660

Alternate gene names: 192290058

Gene position: 1780742-1779123 (Counterclockwise)

Preceding gene: 192290059

Following gene: 192290057

Centisome position: 31.0

GC content: 62.47

Gene sequence:

>1620_bases
ATGAAGCGTCGTGATTTCCTCAAGTCCGCTACAGCCCTCGCCGCCGGCGCGATGGTGCCAGCACCGGCGATTTGGTCGGC
CGCCAAGGCCGACGCCCGGTCCGAAACCCTGCTGGTTGTCTCCGAGAGCGGCCCGAACAACCTCGACATCCACGGCGTCG
GCACCAACGTGCCCGGCTACGAGGTGTCGTGGAATTGCTACGACCGGCTGATCACCCACGAAATGAAGGAAGGCCCCGGC
GGCGTTCCCTACTACGATAAGGACAAGTTCAAGGGCGAGCTCGCCGACGACATGGTCATCGGCGACATGTCTGCGACCTT
CAAGCTGAAGAAGAACGCCACCTTCCAGGACGGCACCCCGGTCACCGCCAAGGACGTGAAGTGGTCGCTCGACCGCTCGG
TCAGCGTCGGCGGCTTTCCGACCTTCCAGATGAGCGCCGGCTCGCTGACCAAGCCCGAACAGTTCGTGGTGGTCGACGAT
CACACCGTGCGGGTCGACTTCCTGAAGAAGGACAAGCTCACGATCCCGGATCTCGCGGTGATTGTGCCCTGCGTCGTCAA
TTCCGAACTGGTGAAGAAGAACGCGACCGAAAAAGACCCGTGGGGTCTCGAATACACCAAGCAGAACACAGCCGGTTCCG
GCGCCTATCGGGTGGTGAAGTGGACCGCCGGCACCGAAGTGATCATGGAGCGCAACGACAAGTGGGTCGGCGGCCCGCTG
CCGAAAATCAAGCGCGTGATCTGGCGCATGGTGCCGCAGGCCGGCAACCGCCGGGCACTGCTGGAGCGCGGTGACGCCGA
CATCTCCTATGAGCTGCCGAACCAGGACTTCGCCGAGATGAAGCGCGACGGCAAAGTCAACGTGGTGTCGTTGCCGATCT
CCAACGGCATCCAGTATCTCGGCATGAACGTCACCCAGCCGCCGTTCAACAACCCGAAGGTGCGTGAGGCGGTCGCCTAC
GCGGTGCCATATCAGAAGATCATCGACGCGGTGATGTTCGGCCTCGCCAACCCGATGTTCGGCGCGGCGGCCGACAAGGC
GACCGAAGTGAAGTGGCCGCAGCCGACCAAGTACAATACCGACATGGCGAAGGCCAAGGCGCTGATGGCAGAAGCCGGCT
ACGCGAACGGCTTCGACACCACGCTGTCGTTCGACCTCGGCTTCGCCGGCGTCAACGAGCCGATGTGCATCCTGATCCAG
GAAAGCCTGGCGCAGATCGGCATCCGCTGCACCATCAACAAGATCCCCGGCGCCAACTGGCGCACCGAGCTGAACAAGAA
GGTGATGCCGCTCTACGTCAACATCTTCTCGGGCTGGCTCGATTATCCGGAGTACTTCTTCTACTGGTGCTACCACTCCG
GCAAGTCGATCTTCAACACCATGGGCTACGACTCGCCCGAGATGGACAGGCTGATCGACAGCTCCCGCATCGCCGCAGCA
ACCGGCGAAACCGCGACCTACGACAGCGACGTCAAGGGCTTCGTCGACCTCGCCTTCAAGGACATCCCGCGCGTCCCACT
GTACCAGCCCTACCTCAACGTCGCGATGCAGAAGAACGTCTCCGGCTTCGCCTACTGGTTCCACCGCCGGCTCGACTACC
GGACGATGGTGAAGGGCTGA

Upstream 100 bases:

>100_bases
ATCGAAATATTTCAGATGGTTAGGTCGATTTAGGCGTCTGGCACGAAGCTTGCGAACGAGTTCCATCAGCTACTCATCCT
CGCTGCTTTTGGAGCCGCAT

Downstream 100 bases:

>100_bases
ACGTGAGCACTCTTCTCCCTCTCCCGCTTGCGGGAGAGGGCCGGGGTGAGGGCGACGCGGGAACCGTGCCTGGGGAGCCC
CACCCCCGACCCCTCCCCGC

Product: family 5 extracellular solute-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 539; Mature: 539

Protein sequence:

>539_residues
MKRRDFLKSATALAAGAMVPAPAIWSAAKADARSETLLVVSESGPNNLDIHGVGTNVPGYEVSWNCYDRLITHEMKEGPG
GVPYYDKDKFKGELADDMVIGDMSATFKLKKNATFQDGTPVTAKDVKWSLDRSVSVGGFPTFQMSAGSLTKPEQFVVVDD
HTVRVDFLKKDKLTIPDLAVIVPCVVNSELVKKNATEKDPWGLEYTKQNTAGSGAYRVVKWTAGTEVIMERNDKWVGGPL
PKIKRVIWRMVPQAGNRRALLERGDADISYELPNQDFAEMKRDGKVNVVSLPISNGIQYLGMNVTQPPFNNPKVREAVAY
AVPYQKIIDAVMFGLANPMFGAAADKATEVKWPQPTKYNTDMAKAKALMAEAGYANGFDTTLSFDLGFAGVNEPMCILIQ
ESLAQIGIRCTINKIPGANWRTELNKKVMPLYVNIFSGWLDYPEYFFYWCYHSGKSIFNTMGYDSPEMDRLIDSSRIAAA
TGETATYDSDVKGFVDLAFKDIPRVPLYQPYLNVAMQKNVSGFAYWFHRRLDYRTMVKG

Sequences:

>Translated_539_residues
MKRRDFLKSATALAAGAMVPAPAIWSAAKADARSETLLVVSESGPNNLDIHGVGTNVPGYEVSWNCYDRLITHEMKEGPG
GVPYYDKDKFKGELADDMVIGDMSATFKLKKNATFQDGTPVTAKDVKWSLDRSVSVGGFPTFQMSAGSLTKPEQFVVVDD
HTVRVDFLKKDKLTIPDLAVIVPCVVNSELVKKNATEKDPWGLEYTKQNTAGSGAYRVVKWTAGTEVIMERNDKWVGGPL
PKIKRVIWRMVPQAGNRRALLERGDADISYELPNQDFAEMKRDGKVNVVSLPISNGIQYLGMNVTQPPFNNPKVREAVAY
AVPYQKIIDAVMFGLANPMFGAAADKATEVKWPQPTKYNTDMAKAKALMAEAGYANGFDTTLSFDLGFAGVNEPMCILIQ
ESLAQIGIRCTINKIPGANWRTELNKKVMPLYVNIFSGWLDYPEYFFYWCYHSGKSIFNTMGYDSPEMDRLIDSSRIAAA
TGETATYDSDVKGFVDLAFKDIPRVPLYQPYLNVAMQKNVSGFAYWFHRRLDYRTMVKG
>Mature_539_residues
MKRRDFLKSATALAAGAMVPAPAIWSAAKADARSETLLVVSESGPNNLDIHGVGTNVPGYEVSWNCYDRLITHEMKEGPG
GVPYYDKDKFKGELADDMVIGDMSATFKLKKNATFQDGTPVTAKDVKWSLDRSVSVGGFPTFQMSAGSLTKPEQFVVVDD
HTVRVDFLKKDKLTIPDLAVIVPCVVNSELVKKNATEKDPWGLEYTKQNTAGSGAYRVVKWTAGTEVIMERNDKWVGGPL
PKIKRVIWRMVPQAGNRRALLERGDADISYELPNQDFAEMKRDGKVNVVSLPISNGIQYLGMNVTQPPFNNPKVREAVAY
AVPYQKIIDAVMFGLANPMFGAAADKATEVKWPQPTKYNTDMAKAKALMAEAGYANGFDTTLSFDLGFAGVNEPMCILIQ
ESLAQIGIRCTINKIPGANWRTELNKKVMPLYVNIFSGWLDYPEYFFYWCYHSGKSIFNTMGYDSPEMDRLIDSSRIAAA
TGETATYDSDVKGFVDLAFKDIPRVPLYQPYLNVAMQKNVSGFAYWFHRRLDYRTMVKG

Specific function: Part of the ABC transporter complex ddpABCDF, which is probably involved in D,D-dipeptide transport [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1787762, Length=506, Percent_Identity=28.2608695652174, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI1787052, Length=485, Percent_Identity=25.979381443299, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1789966, Length=442, Percent_Identity=26.9230769230769, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1787495, Length=531, Percent_Identity=23.9171374764595, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1787551, Length=388, Percent_Identity=23.9690721649485, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789887, Length=234, Percent_Identity=27.3504273504274, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 59973; Mature: 59973

Theoretical pI: Translated: 8.37; Mature: 8.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRRDFLKSATALAAGAMVPAPAIWSAAKADARSETLLVVSESGPNNLDIHGVGTNVPGY
CCHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCEEEEEECCCCCCEEEEEECCCCCCE
EVSWNCYDRLITHEMKEGPGGVPYYDKDKFKGELADDMVIGDMSATFKLKKNATFQDGTP
EEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECCCEEEEEECCCCCCCCCC
VTAKDVKWSLDRSVSVGGFPTFQMSAGSLTKPEQFVVVDDHTVRVDFLKKDKLTIPDLAV
CCHHCCEEECCCCEECCCCCEEEECCCCCCCCCEEEEECCCEEEEEEEECCCCCCCCHHH
IVPCVVNSELVKKNATEKDPWGLEYTKQNTAGSGAYRVVKWTAGTEVIMERNDKWVGGPL
HHHHHCCHHHHHCCCCCCCCCCCEEECCCCCCCCCEEEEEEECCCEEEEECCCCCCCCCH
PKIKRVIWRMVPQAGNRRALLERGDADISYELPNQDFAEMKRDGKVNVVSLPISNGIQYL
HHHHHHHHHHCCCCCCCEEHEECCCCCEEEECCCCHHHHHHCCCCEEEEEEECCCCCEEE
GMNVTQPPFNNPKVREAVAYAVPYQKIIDAVMFGLANPMFGAAADKATEVKWPQPTKYNT
CCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
DMAKAKALMAEAGYANGFDTTLSFDLGFAGVNEPMCILIQESLAQIGIRCTINKIPGANW
HHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCEEEEEEHHHHHCCEEEEEECCCCCCC
RTELNKKVMPLYVNIFSGWLDYPEYFFYWCYHSGKSIFNTMGYDSPEMDRLIDSSRIAAA
HHHHCCCEEEEHEEHHHHHHCCCCCEEEEEECCCCHHHHHCCCCCHHHHHHHCCCCEEEE
TGETATYDSDVKGFVDLAFKDIPRVPLYQPYLNVAMQKNVSGFAYWFHRRLDYRTMVKG
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCHHHHHHHHHCCHHHHCCC
>Mature Secondary Structure
MKRRDFLKSATALAAGAMVPAPAIWSAAKADARSETLLVVSESGPNNLDIHGVGTNVPGY
CCHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCEEEEEECCCCCCEEEEEECCCCCCE
EVSWNCYDRLITHEMKEGPGGVPYYDKDKFKGELADDMVIGDMSATFKLKKNATFQDGTP
EEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECCCEEEEEECCCCCCCCCC
VTAKDVKWSLDRSVSVGGFPTFQMSAGSLTKPEQFVVVDDHTVRVDFLKKDKLTIPDLAV
CCHHCCEEECCCCEECCCCCEEEECCCCCCCCCEEEEECCCEEEEEEEECCCCCCCCHHH
IVPCVVNSELVKKNATEKDPWGLEYTKQNTAGSGAYRVVKWTAGTEVIMERNDKWVGGPL
HHHHHCCHHHHHCCCCCCCCCCCEEECCCCCCCCCEEEEEEECCCEEEEECCCCCCCCCH
PKIKRVIWRMVPQAGNRRALLERGDADISYELPNQDFAEMKRDGKVNVVSLPISNGIQYL
HHHHHHHHHHCCCCCCCEEHEECCCCCEEEECCCCHHHHHHCCCCEEEEEEECCCCCEEE
GMNVTQPPFNNPKVREAVAYAVPYQKIIDAVMFGLANPMFGAAADKATEVKWPQPTKYNT
CCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
DMAKAKALMAEAGYANGFDTTLSFDLGFAGVNEPMCILIQESLAQIGIRCTINKIPGANW
HHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCEEEEEEHHHHHCCEEEEEECCCCCCC
RTELNKKVMPLYVNIFSGWLDYPEYFFYWCYHSGKSIFNTMGYDSPEMDRLIDSSRIAAA
HHHHCCCEEEEHEEHHHHHHCCCCCEEEEEECCCCHHHHHCCCCCHHHHHHHCCCCEEEE
TGETATYDSDVKGFVDLAFKDIPRVPLYQPYLNVAMQKNVSGFAYWFHRRLDYRTMVKG
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCHHHHHHHHHCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 9751644 [H]