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The map label for this gene is ywlC [H]

Identifier: 192289677

GI number: 192289677

Start: 1340615

End: 1341595

Strand: Reverse

Name: ywlC [H]

Synonym: Rpal_1267

Alternate gene names: 192289677

Gene position: 1341595-1340615 (Counterclockwise)

Preceding gene: 192289681

Following gene: 192289676

Centisome position: 23.36

GC content: 69.93

Gene sequence:

>981_bases
ATGCTCGACCTGATCACCAAGAGGCTGACCGCAGCGGATGCGGACAAAGCCGCGCGCGCGCTGCGCGGCGGTGGGCTGGT
CGCGTTCCCGACCGAGACGGTGTACGGGCTCGGCGCCGATGCATCGAATGCCGAAGCGGTGGCGCGGCTATACGCTGCCA
AGGGCCGGCCGTCGTTCAACCCGCTGATCGCGCATGTCGCCGATCTCGATGCTGCGCGCACCATCGCAAGGTTCGATGCG
GCCGCGCTCCGCCTCGCCGAGGCATTCTGGCCAGGGCCGCTGACGCTGGTGCTGCCGAAGCAGGCGGACTGTTCCGTCTG
CGACCTCGCCACCGCCGGGCTGGACAGCGTCGCGATCCGCATCCCGTCGCATCCGGTGGCGCAGGCACTATTGCGCGCGT
TTGGTGGGCCCGTGGTGGCGCCGTCCGCCAACAGGTCCGGTCACGTGTCGCCGACCACAGCGGCGCATGTCGCTTCCGAT
CTCGACGGCCGGATCGATGTGATCGTCGACGGCGGACCGGTGATGGTCGGCGTCGAGTCGACGATCGTCAGTTGCCTCGG
CGCACCAGTTCTGCTGCGGCCCGGCGGCCTGCCGCGCGAAGCGATCGAGCGCGTACTCGGTCAAGCGCTAGGCACACCGA
CGACTAACAACGCCGACGATCACGCGCCTCTCGCACCAGGGATGCTGGCGTCGCACTACGCGCCGCGTGCGCTGGTACGG
CTGAATGCGACCGAGGTGAAGCCGGGCGAAGCGCTGCTGGCGTTCGGCCCTGAGTTGCCGCCGGGCGCCGAGACAGCCGC
CGCGGTCCACAACCTCTCGCCGCGCGGTGACCTCCCCGAAGCCGCAGCACATCTGTTCGGCGCGCTTCGCGCGCTCGACG
ATCGCGGCGCACGTGGCATCGCCGTGATGCCGATCCCGTTTCACGGACTCGGCGAAGCGATCAACGATCGCCTGCGCCGC
GCAGCGGCACCACGCCCATGA

Upstream 100 bases:

>100_bases
CTGAGCAAGACCGCGCCACGCAGCTCTCGCGCGCATGCAGCGCAGCGCGTCGACTTTGCTACTTCGCATCCGCACGAATT
GCGATATGAAACCGGAAATG

Downstream 100 bases:

>100_bases
CAAACCAACAAGCAGATCGCGACGTCGTCGCAAGCGAAACGAAGCAATCCAAAGGCGTCTAAGACGCGTTTCGGATCGGT
CGCTTCGCGCCTCGCGACGA

Product: Sua5/YciO/YrdC/YwlC family protein

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MLDLITKRLTAADADKAARALRGGGLVAFPTETVYGLGADASNAEAVARLYAAKGRPSFNPLIAHVADLDAARTIARFDA
AALRLAEAFWPGPLTLVLPKQADCSVCDLATAGLDSVAIRIPSHPVAQALLRAFGGPVVAPSANRSGHVSPTTAAHVASD
LDGRIDVIVDGGPVMVGVESTIVSCLGAPVLLRPGGLPREAIERVLGQALGTPTTNNADDHAPLAPGMLASHYAPRALVR
LNATEVKPGEALLAFGPELPPGAETAAAVHNLSPRGDLPEAAAHLFGALRALDDRGARGIAVMPIPFHGLGEAINDRLRR
AAAPRP

Sequences:

>Translated_326_residues
MLDLITKRLTAADADKAARALRGGGLVAFPTETVYGLGADASNAEAVARLYAAKGRPSFNPLIAHVADLDAARTIARFDA
AALRLAEAFWPGPLTLVLPKQADCSVCDLATAGLDSVAIRIPSHPVAQALLRAFGGPVVAPSANRSGHVSPTTAAHVASD
LDGRIDVIVDGGPVMVGVESTIVSCLGAPVLLRPGGLPREAIERVLGQALGTPTTNNADDHAPLAPGMLASHYAPRALVR
LNATEVKPGEALLAFGPELPPGAETAAAVHNLSPRGDLPEAAAHLFGALRALDDRGARGIAVMPIPFHGLGEAINDRLRR
AAAPRP
>Mature_326_residues
MLDLITKRLTAADADKAARALRGGGLVAFPTETVYGLGADASNAEAVARLYAAKGRPSFNPLIAHVADLDAARTIARFDA
AALRLAEAFWPGPLTLVLPKQADCSVCDLATAGLDSVAIRIPSHPVAQALLRAFGGPVVAPSANRSGHVSPTTAAHVASD
LDGRIDVIVDGGPVMVGVESTIVSCLGAPVLLRPGGLPREAIERVLGQALGTPTTNNADDHAPLAPGMLASHYAPRALVR
LNATEVKPGEALLAFGPELPPGAETAAAVHNLSPRGDLPEAAAHLFGALRALDDRGARGIAVMPIPFHGLGEAINDRLRR
AAAPRP

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Escherichia coli, GI87081864, Length=184, Percent_Identity=27.7173913043478, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI2367210, Length=127, Percent_Identity=36.2204724409449, Blast_Score=73, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17537239, Length=207, Percent_Identity=32.3671497584541, Blast_Score=79, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6321269, Length=380, Percent_Identity=36.0526315789474, Blast_Score=166, Evalue=4e-42,
Organism=Drosophila melanogaster, GI78707274, Length=169, Percent_Identity=30.7692307692308, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 33439; Mature: 33439

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDLITKRLTAADADKAARALRGGGLVAFPTETVYGLGADASNAEAVARLYAAKGRPSFN
CHHHHHHHHHHCCHHHHHHHHHCCCEEEECCCCEEECCCCCCCHHHHHHHHHHCCCCCCC
PLIAHVADLDAARTIARFDAAALRLAEAFWPGPLTLVLPKQADCSVCDLATAGLDSVAIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHCCCCEEEEE
IPSHPVAQALLRAFGGPVVAPSANRSGHVSPTTAAHVASDLDGRIDVIVDGGPVMVGVES
CCCCHHHHHHHHHHCCCEECCCCCCCCCCCCHHHHHHHHCCCCCEEEEECCCCEEEEHHH
TIVSCLGAPVLLRPGGLPREAIERVLGQALGTPTTNNADDHAPLAPGMLASHYAPRALVR
HHHHHHCCCEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHCCCCEEEE
LNATEVKPGEALLAFGPELPPGAETAAAVHNLSPRGDLPEAAAHLFGALRALDDRGARGI
ECCCCCCCCCEEEEECCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCE
AVMPIPFHGLGEAINDRLRRAAAPRP
EEEECCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLDLITKRLTAADADKAARALRGGGLVAFPTETVYGLGADASNAEAVARLYAAKGRPSFN
CHHHHHHHHHHCCHHHHHHHHHCCCEEEECCCCEEECCCCCCCHHHHHHHHHHCCCCCCC
PLIAHVADLDAARTIARFDAAALRLAEAFWPGPLTLVLPKQADCSVCDLATAGLDSVAIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHCCCCEEEEE
IPSHPVAQALLRAFGGPVVAPSANRSGHVSPTTAAHVASDLDGRIDVIVDGGPVMVGVES
CCCCHHHHHHHHHHCCCEECCCCCCCCCCCCHHHHHHHHCCCCCEEEEECCCCEEEEHHH
TIVSCLGAPVLLRPGGLPREAIERVLGQALGTPTTNNADDHAPLAPGMLASHYAPRALVR
HHHHHHCCCEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHCCCCEEEE
LNATEVKPGEALLAFGPELPPGAETAAAVHNLSPRGDLPEAAAHLFGALRALDDRGARGI
ECCCCCCCCCEEEEECCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCE
AVMPIPFHGLGEAINDRLRRAAAPRP
EEEECCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]