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The map label for this gene is gcp [H]

Identifier: 192288687

GI number: 192288687

Start: 271388

End: 272479

Strand: Reverse

Name: gcp [H]

Synonym: Rpal_0256

Alternate gene names: 192288687

Gene position: 272479-271388 (Counterclockwise)

Preceding gene: 192288691

Following gene: 192288686

Centisome position: 4.74

GC content: 68.59

Gene sequence:

>1092_bases
TTGACTAGTGAACAAGCCTTGCTGGTGCTGGGGATCGAGACCACCTGCGATGAAACCGCAGCCGCCGTGGTCGAGCGTCG
CGCCGACGGCAGCGGGCGCCTCCTCTCCAATATCGTGCGTTCCCAGACCGATGAACACGCCCCCTTTGGTGGCGTCGTCC
CGGAGATCGCCGCGCGCGCCCATGTCGATGTGCTCGACGGCATTATCGCGGCGGCGATGAACGAAGCCGGCGTGGCGTTC
GCCAGTCTGTCCGGGGTTGCGGCAGCCGCCGGGCCAGGGCTGATCGGTGGCGTGATCGTCGGACTGACCACCGCCAAGGC
GATTGCGCTGGTGCACGGCACACCGCTGATCGCGGTCAATCACCTCGAAGCCCATGCGCTGACGCCGCGGCTGACCGACG
CGGTCGAGTTTCCCTACTGTCTGTTCCTCGCGTCCGGCGGCCACACCCAGATCGTCGCGGTGCTCGGCGTCGGCAACTAC
GTCCGGCTCGGCACCACGGTCGACGACGCGATCGGCGAGGCATTCGACAAGATCGCCAAGATGCTCGGCCTGCCCTACCC
CGGCGGCCCTCAGGTCGAGCGCGCCGCCGAAGCCGGCGATCCCAACCGCTTCGCATTTCCCCGCCCGATGCTGGGGCGCC
AGGATGCTAATTTCTCTCTGTCTGGGCTGAAGACTGCGGTCCGCAACGAGGCCGGTAAGCTGACGCCGCTCGATCCGCAG
GACATCAACGATCTGTGCGCGGGCTTTCAGGCCGCGGTGCTGGAATCGGTGGCCGACCGGCTCGGCGCCGGGCTGCGGCT
GTTCAAGGAACGGTTCGGGCCGCCGAAGGCGCTGGTCGCGGCCGGCGGCGCCGCCGCCAATCAGGCGATCCGCCGGATGC
TGCGCGAAGTCGCCGCCAAGGTGCAGACCACGCTGATCGTGCCGCCGCCGTCGCTGTGCACCGACAATGGCGCGATGATC
GCCTGGGCTGGAGCCGAGCGGCTGGCGCTCGGCCTCACCGATACGATGGATACCGCGCCGCGCGCGCGTTGGCTGCTCGA
CGCCAACGCCACCGCACCGGCGAAATTTGCCAACACGCGTGCCGGGTTCTAA

Upstream 100 bases:

>100_bases
GGGGCCGCAGGGCGCCAAGGGGATGATTGCATTCCAAGACCCCGCAATGCTACGCGAGGCAAGGAGAACGCCGGTTCGGG
CGTAAACGCAAGGGCTCAAT

Downstream 100 bases:

>100_bases
GGCCGGGCTGTGTCGGTGGCTTGGATGATGTTGCGATGGGTTCGTTGAATTCGATTGCCGTGCTCGGCGGCGGTGCCTGG
GGCACCGCGCTGGCGCAGAC

Product: DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MTSEQALLVLGIETTCDETAAAVVERRADGSGRLLSNIVRSQTDEHAPFGGVVPEIAARAHVDVLDGIIAAAMNEAGVAF
ASLSGVAAAAGPGLIGGVIVGLTTAKAIALVHGTPLIAVNHLEAHALTPRLTDAVEFPYCLFLASGGHTQIVAVLGVGNY
VRLGTTVDDAIGEAFDKIAKMLGLPYPGGPQVERAAEAGDPNRFAFPRPMLGRQDANFSLSGLKTAVRNEAGKLTPLDPQ
DINDLCAGFQAAVLESVADRLGAGLRLFKERFGPPKALVAAGGAAANQAIRRMLREVAAKVQTTLIVPPPSLCTDNGAMI
AWAGAERLALGLTDTMDTAPRARWLLDANATAPAKFANTRAGF

Sequences:

>Translated_363_residues
MTSEQALLVLGIETTCDETAAAVVERRADGSGRLLSNIVRSQTDEHAPFGGVVPEIAARAHVDVLDGIIAAAMNEAGVAF
ASLSGVAAAAGPGLIGGVIVGLTTAKAIALVHGTPLIAVNHLEAHALTPRLTDAVEFPYCLFLASGGHTQIVAVLGVGNY
VRLGTTVDDAIGEAFDKIAKMLGLPYPGGPQVERAAEAGDPNRFAFPRPMLGRQDANFSLSGLKTAVRNEAGKLTPLDPQ
DINDLCAGFQAAVLESVADRLGAGLRLFKERFGPPKALVAAGGAAANQAIRRMLREVAAKVQTTLIVPPPSLCTDNGAMI
AWAGAERLALGLTDTMDTAPRARWLLDANATAPAKFANTRAGF
>Mature_362_residues
TSEQALLVLGIETTCDETAAAVVERRADGSGRLLSNIVRSQTDEHAPFGGVVPEIAARAHVDVLDGIIAAAMNEAGVAFA
SLSGVAAAAGPGLIGGVIVGLTTAKAIALVHGTPLIAVNHLEAHALTPRLTDAVEFPYCLFLASGGHTQIVAVLGVGNYV
RLGTTVDDAIGEAFDKIAKMLGLPYPGGPQVERAAEAGDPNRFAFPRPMLGRQDANFSLSGLKTAVRNEAGKLTPLDPQD
INDLCAGFQAAVLESVADRLGAGLRLFKERFGPPKALVAAGGAAANQAIRRMLREVAAKVQTTLIVPPPSLCTDNGAMIA
WAGAERLALGLTDTMDTAPRARWLLDANATAPAKFANTRAGF

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI116812636, Length=342, Percent_Identity=37.1345029239766, Blast_Score=204, Evalue=1e-52,
Organism=Homo sapiens, GI8923380, Length=346, Percent_Identity=27.4566473988439, Blast_Score=102, Evalue=6e-22,
Organism=Escherichia coli, GI1789445, Length=341, Percent_Identity=43.4017595307918, Blast_Score=258, Evalue=5e-70,
Organism=Caenorhabditis elegans, GI17557464, Length=328, Percent_Identity=33.5365853658537, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI71995670, Length=350, Percent_Identity=28.5714285714286, Blast_Score=105, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6320099, Length=366, Percent_Identity=29.2349726775956, Blast_Score=145, Evalue=9e-36,
Organism=Saccharomyces cerevisiae, GI6322891, Length=319, Percent_Identity=26.0188087774295, Blast_Score=77, Evalue=3e-15,
Organism=Drosophila melanogaster, GI20129063, Length=342, Percent_Identity=35.9649122807018, Blast_Score=194, Evalue=8e-50,
Organism=Drosophila melanogaster, GI21357207, Length=340, Percent_Identity=27.0588235294118, Blast_Score=110, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 37494; Mature: 37363

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSEQALLVLGIETTCDETAAAVVERRADGSGRLLSNIVRSQTDEHAPFGGVVPEIAARA
CCCCCEEEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
HVDVLDGIIAAAMNEAGVAFASLSGVAAAAGPGLIGGVIVGLTTAKAIALVHGTPLIAVN
HHHHHHHHHHHHHHHCCHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHEEEEECCCEEEEE
HLEAHALTPRLTDAVEFPYCLFLASGGHTQIVAVLGVGNYVRLGTTVDDAIGEAFDKIAK
CCHHHHCCCCHHHHHCCCEEEEEECCCCEEEEEEEECCCEEEECCCHHHHHHHHHHHHHH
MLGLPYPGGPQVERAAEAGDPNRFAFPRPMLGRQDANFSLSGLKTAVRNEAGKLTPLDPQ
HHCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCC
DINDLCAGFQAAVLESVADRLGAGLRLFKERFGPPKALVAAGGAAANQAIRRMLREVAAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHH
VQTTLIVPPPSLCTDNGAMIAWAGAERLALGLTDTMDTAPRARWLLDANATAPAKFANTR
HHEEEEECCCCCCCCCCCEEEECCCCCEEECCCCCCCCCCCCEEEEECCCCCCHHHCCCC
AGF
CCC
>Mature Secondary Structure 
TSEQALLVLGIETTCDETAAAVVERRADGSGRLLSNIVRSQTDEHAPFGGVVPEIAARA
CCCCEEEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
HVDVLDGIIAAAMNEAGVAFASLSGVAAAAGPGLIGGVIVGLTTAKAIALVHGTPLIAVN
HHHHHHHHHHHHHHHCCHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHEEEEECCCEEEEE
HLEAHALTPRLTDAVEFPYCLFLASGGHTQIVAVLGVGNYVRLGTTVDDAIGEAFDKIAK
CCHHHHCCCCHHHHHCCCEEEEEECCCCEEEEEEEECCCEEEECCCHHHHHHHHHHHHHH
MLGLPYPGGPQVERAAEAGDPNRFAFPRPMLGRQDANFSLSGLKTAVRNEAGKLTPLDPQ
HHCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCC
DINDLCAGFQAAVLESVADRLGAGLRLFKERFGPPKALVAAGGAAANQAIRRMLREVAAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHH
VQTTLIVPPPSLCTDNGAMIAWAGAERLALGLTDTMDTAPRARWLLDANATAPAKFANTR
HHEEEEECCCCCCCCCCCEEEECCCCCEEECCCCCCCCCCCCEEEEECCCCCCHHHCCCC
AGF
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA