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The map label for this gene is ucpA [C]

Identifier: 192288458

GI number: 192288458

Start: 25778

End: 26653

Strand: Reverse

Name: ucpA [C]

Synonym: Rpal_0025

Alternate gene names: 192288458

Gene position: 26653-25778 (Counterclockwise)

Preceding gene: 192288459

Following gene: 192288456

Centisome position: 0.46

GC content: 65.53

Gene sequence:

>876_bases
ATGGCATCACTGCAAGGCAAGACGCTGTTCATCACCGGGGCGAGCCGGGGAATCGGGCTCGCGATCGCCCTGCGGGCGGC
GCGGGATGGAGCCAATGTGGCGATCGCCGCCAAGACCACCGAGCCGCATCCGAAGCTGAAGGGCACGATCTACACCGCGG
CCGAGGAGATCGTCGCGGCGGGCGGCAAGGCGCTGCCGATGGTCTGCGACATCCGCGACGAGGCGCAGGTGATCGACGCG
ATCGGCAAGACGGTGGCGGAGTTCGGCGGTATCGACATCTGCGTCAACAACGCCAGCGCGATCAGCCTGACGAATTCGCA
GGCGACCGACATGAAGCGCTACGACCTGATGATGGGAATCAACACCCGCGGGACCTTCATGGTGTCGAAATATTGCATCC
CGCACCTGAAGAAGGCGGCCAATCCGCACATCCTGATGCTGTCGCCGCCGCTCGACATGAAGGCGAAGTGGTTCGCAGCG
TCGACTGCCTACACCATGGCGAAGTTCGGCATGAGCATGGTGGCGCTCGGTCTCTCGGGCGAACTGAAGCACGCCGGCGT
TGCGGTGAATGCGCTGTGGCCGCGCACCACGATCGCGACCGCCGCGGTCGGCAATCTGCTCGGCGGCGACGCGATGATCC
GCGCGAGCCGCACGCCGGAGATCATGGGTGACGCCGCCCATGCGATCCTGGCCCGTCCCTCGCGTGAATTCACCGGCCAG
TTCTGCATCGACGACAGCGTGTTGTATGAAGCCGGCGTGCGCGACTTCGAGCCATATCGCGTCGATCCGAGCGTGCCGCT
GATGTCGGACTTCTTTGTTCCGGACGACAGCGTTCCGCCGCCCGGCGTGACCGTCACGCCGCTGCCGATGGGGTAG

Upstream 100 bases:

>100_bases
CCGGTCGCTTTGGCTAGCCTTCCGATGATTTCGAGTTTCACAGAACCGGAGCTACCCTCGCTGGATGGCGATCGGGTTCG
CGTCAGGGAGAGGGCATCAG

Downstream 100 bases:

>100_bases
GTGCCGAACGTCAAGCTCGTCATTGCGGGGAGCGAAGCGACTAAGCCATCCAGGAACGCCGAGTACGGAGCCTCTGGATT
GCTTCGCTTCGCTCGTAGTC

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MASLQGKTLFITGASRGIGLAIALRAARDGANVAIAAKTTEPHPKLKGTIYTAAEEIVAAGGKALPMVCDIRDEAQVIDA
IGKTVAEFGGIDICVNNASAISLTNSQATDMKRYDLMMGINTRGTFMVSKYCIPHLKKAANPHILMLSPPLDMKAKWFAA
STAYTMAKFGMSMVALGLSGELKHAGVAVNALWPRTTIATAAVGNLLGGDAMIRASRTPEIMGDAAHAILARPSREFTGQ
FCIDDSVLYEAGVRDFEPYRVDPSVPLMSDFFVPDDSVPPPGVTVTPLPMG

Sequences:

>Translated_291_residues
MASLQGKTLFITGASRGIGLAIALRAARDGANVAIAAKTTEPHPKLKGTIYTAAEEIVAAGGKALPMVCDIRDEAQVIDA
IGKTVAEFGGIDICVNNASAISLTNSQATDMKRYDLMMGINTRGTFMVSKYCIPHLKKAANPHILMLSPPLDMKAKWFAA
STAYTMAKFGMSMVALGLSGELKHAGVAVNALWPRTTIATAAVGNLLGGDAMIRASRTPEIMGDAAHAILARPSREFTGQ
FCIDDSVLYEAGVRDFEPYRVDPSVPLMSDFFVPDDSVPPPGVTVTPLPMG
>Mature_290_residues
ASLQGKTLFITGASRGIGLAIALRAARDGANVAIAAKTTEPHPKLKGTIYTAAEEIVAAGGKALPMVCDIRDEAQVIDAI
GKTVAEFGGIDICVNNASAISLTNSQATDMKRYDLMMGINTRGTFMVSKYCIPHLKKAANPHILMLSPPLDMKAKWFAAS
TAYTMAKFGMSMVALGLSGELKHAGVAVNALWPRTTIATAAVGNLLGGDAMIRASRTPEIMGDAAHAILARPSREFTGQF
CIDDSVLYEAGVRDFEPYRVDPSVPLMSDFFVPDDSVPPPGVTVTPLPMG

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254986, Length=272, Percent_Identity=56.9852941176471, Blast_Score=314, Evalue=6e-86,
Organism=Homo sapiens, GI209862901, Length=201, Percent_Identity=29.3532338308458, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI19923983, Length=201, Percent_Identity=29.3532338308458, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI19923817, Length=207, Percent_Identity=27.0531400966184, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI10190704, Length=249, Percent_Identity=27.710843373494, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI4504505, Length=193, Percent_Identity=26.9430051813472, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI87082100, Length=195, Percent_Identity=33.3333333333333, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1789208, Length=193, Percent_Identity=27.979274611399, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71982365, Length=271, Percent_Identity=58.6715867158672, Blast_Score=328, Evalue=2e-90,
Organism=Caenorhabditis elegans, GI17558628, Length=276, Percent_Identity=58.695652173913, Blast_Score=318, Evalue=2e-87,
Organism=Caenorhabditis elegans, GI17559104, Length=204, Percent_Identity=28.921568627451, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17562910, Length=225, Percent_Identity=29.3333333333333, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17531453, Length=202, Percent_Identity=28.2178217821782, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17562908, Length=202, Percent_Identity=27.2277227722772, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17562906, Length=202, Percent_Identity=27.2277227722772, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17560220, Length=203, Percent_Identity=32.0197044334975, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI21357673, Length=278, Percent_Identity=62.589928057554, Blast_Score=347, Evalue=6e-96,
Organism=Drosophila melanogaster, GI28571526, Length=195, Percent_Identity=33.3333333333333, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI21357041, Length=199, Percent_Identity=31.1557788944724, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24644339, Length=196, Percent_Identity=29.5918367346939, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI23397609, Length=192, Percent_Identity=29.6875, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21355319, Length=209, Percent_Identity=25.3588516746411, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 30714; Mature: 30583

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASLQGKTLFITGASRGIGLAIALRAARDGANVAIAAKTTEPHPKLKGTIYTAAEEIVAA
CCCCCCCEEEEEECCCCCEEEEEEEECCCCCCEEEEEECCCCCCCCCEEEEHHHHHHHHC
GGKALPMVCDIRDEAQVIDAIGKTVAEFGGIDICVNNASAISLTNSQATDMKRYDLMMGI
CCCCCEEEECCCHHHHHHHHHHHHHHHHCCEEEEECCCCEEEECCCCCCCHHHEEEEEEC
NTRGTFMVSKYCIPHLKKAANPHILMLSPPLDMKAKWFAASTAYTMAKFGMSMVALGLSG
CCCCEEEEEHHHHHHHHHCCCCEEEEECCCCCCCEEEEEHHHHHHHHHHCHHEEEECCCC
ELKHAGVAVNALWPRTTIATAAVGNLLGGDAMIRASRTPEIMGDAAHAILARPSREFTGQ
CCCCCCEEEEEECCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCHHHCCE
FCIDDSVLYEAGVRDFEPYRVDPSVPLMSDFFVPDDSVPPPGVTVTPLPMG
EEECCHHHHHCCCCCCCCEEECCCCCCHHCCCCCCCCCCCCCCEEECCCCC
>Mature Secondary Structure 
ASLQGKTLFITGASRGIGLAIALRAARDGANVAIAAKTTEPHPKLKGTIYTAAEEIVAA
CCCCCCEEEEEECCCCCEEEEEEEECCCCCCEEEEEECCCCCCCCCEEEEHHHHHHHHC
GGKALPMVCDIRDEAQVIDAIGKTVAEFGGIDICVNNASAISLTNSQATDMKRYDLMMGI
CCCCCEEEECCCHHHHHHHHHHHHHHHHCCEEEEECCCCEEEECCCCCCCHHHEEEEEEC
NTRGTFMVSKYCIPHLKKAANPHILMLSPPLDMKAKWFAASTAYTMAKFGMSMVALGLSG
CCCCEEEEEHHHHHHHHHCCCCEEEEECCCCCCCEEEEEHHHHHHHHHHCHHEEEECCCC
ELKHAGVAVNALWPRTTIATAAVGNLLGGDAMIRASRTPEIMGDAAHAILARPSREFTGQ
CCCCCCEEEEEECCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCHHHCCE
FCIDDSVLYEAGVRDFEPYRVDPSVPLMSDFFVPDDSVPPPGVTVTPLPMG
EEECCHHHHHCCCCCCCCEEECCCCCCHHCCCCCCCCCCCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]