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The map label for this gene is virB2c [H]

Identifier: 190895237

GI number: 190895237

Start: 999462

End: 999761

Strand: Reverse

Name: virB2c [H]

Synonym: RHECIAT_PC0000910

Alternate gene names: 190895237

Gene position: 999761-999462 (Counterclockwise)

Preceding gene: 190895238

Following gene: 190895236

Centisome position: 91.59

GC content: 61.67

Gene sequence:

>300_bases
ATGATCTCCAAAGCCAGCCTTCGCCCGCTTGCCGCATCCACCCTCATGGCGGCCGCCATCCTCGCCTGCCTGGTCGAACC
AGCTTTCGCCCAGGCCGCCGGTATCGAAAGCGTCCTGCAGAACATCGTCGACATGCTGACCGGCAATATCGCCCGTCTGC
TGGCCGTTATCGCCGTCATCATCATCTGCATCGCCTGGATGTTCGGCTACATGGATTTGAGGCGCGCCGGCTTCTGGATC
ATCGGGATCGGCGGCATTTTCGGCGCCACCGAGCTGGTCAACACCATCGTCGGGAACTGA

Upstream 100 bases:

>100_bases
AATCCTCCCAAACCACCGAGGCCGCGTCCTGGGACGTTTTCAGCTCCCGGCGGCAATCCGCGGTTCTCGTTTTCCAGAAT
GATCGATCGGAGCAAAGTGA

Downstream 100 bases:

>100_bases
ACGCTATGGTGAGCATTCAGAGCCTTGAAGATGATACGCTGTTTCTCGCCTGCACCCGCCCGGCAATGATTGCCGGCGTG
ACGATGGAGGCGATGGGCGT

Product: transport secretion system IV protein, VirB2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 99; Mature: 99

Protein sequence:

>99_residues
MISKASLRPLAASTLMAAAILACLVEPAFAQAAGIESVLQNIVDMLTGNIARLLAVIAVIIICIAWMFGYMDLRRAGFWI
IGIGGIFGATELVNTIVGN

Sequences:

>Translated_99_residues
MISKASLRPLAASTLMAAAILACLVEPAFAQAAGIESVLQNIVDMLTGNIARLLAVIAVIIICIAWMFGYMDLRRAGFWI
IGIGGIFGATELVNTIVGN
>Mature_99_residues
MISKASLRPLAASTLMAAAILACLVEPAFAQAAGIESVLQNIVDMLTGNIARLLAVIAVIIICIAWMFGYMDLRRAGFWI
IGIGGIFGATELVNTIVGN

Specific function: Component of the type IV secretion system virB/virD4 which could be a major virulence determinant for subversion of human endothelial cell (HEC) function. VirB2 seems to constitue the major pilus component [H]

COG id: COG3838

COG function: function code U; Type IV secretory pathway, VirB2 components (pilins)

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the virB2 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007039 [H]

Pfam domain/function: PF04956 TrbC [H]

EC number: NA

Molecular weight: Translated: 10393; Mature: 10393

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISKASLRPLAASTLMAAAILACLVEPAFAQAAGIESVLQNIVDMLTGNIARLLAVIAVI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
IICIAWMFGYMDLRRAGFWIIGIGGIFGATELVNTIVGN
HHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MISKASLRPLAASTLMAAAILACLVEPAFAQAAGIESVLQNIVDMLTGNIARLLAVIAVI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
IICIAWMFGYMDLRRAGFWIIGIGGIFGATELVNTIVGN
HHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA