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The map label for this gene is rmrA [H]

Identifier: 190894679

GI number: 190894679

Start: 368802

End: 369986

Strand: Reverse

Name: rmrA [H]

Synonym: RHECIAT_PC0000342

Alternate gene names: 190894679

Gene position: 369986-368802 (Counterclockwise)

Preceding gene: 190894681

Following gene: 190894678

Centisome position: 33.9

GC content: 62.95

Gene sequence:

>1185_bases
ATGTCCATCAAAACGCTGCAGGCCCTGAACAACAACGCGCCTGCTCCGGAAACCACGGCCGAAGCCGCACCCGCAACGCT
CGATGCCGGCGCCACGCCGCACTTGGTCGAACCTGCCGTGCTCTCGGAGCCTCCCGCCCGTAGGCGCACTGGCCGCGGAT
TGCTGCTCGGCGCAACGGCCGTCGTCCTGATCGCTGCAACCGCTTATTACGGCCACAACTACTGGACCGTCGGCCGCTTC
GAGATTGCGACGGATGATGCCTATGTGAAGGCCGACAACACGACCGTCGCACCGAAGGTTTCGGGCTATATCGCAGAAGT
GCTCGTCAGCGATAACGCGGTGGTCAAGGCCGGTCAGCCGCTTGCCCGCATCGATGATCGCGATTTCCGCGCCGCTCTCG
ATCAGACCAAGGCCGATGTCGCCGCGGCGGAGGCGACGCTCAATGCCAAGCAGGCCTCGCTCGACATTCAGCAGTCGACG
ATTGCCGCCGCCCGCGCCACGGTGGAGGTCGACAAGGCCAATGAGACCTTTGCCGAACAAAACAACAAGCGCTATGCAAA
TCTCGCAACCAACGGCTACGCGCCGGTTCAGACCGCGCAGCAGGCGGCTTCCACCATCGCTGCAGCCCAGGCGACCATCA
CTCGTGATACGGCAGCCCTAGATGCCGCCGTCAAACAGGTCGAGCTCCTGAATGCCGAGCTTGCTCAGGCAAGAGCGACT
CTCGCCCATGACCAGGCCGTCCAGCATCAGGCCGAACTGAACCTCTCCTATGCGACCATTACCGCACCCGTCGACGGCAC
CATCGGCAACCGCACGCTGCGTATCGGCCAATATGTTCAGGCCGGCACTCAGCTGATGTCGGTCGTGCCGACGAGCGCGG
TCTATGTGATCGCCAACTATAAGGAAACGCAACTCACCGATGTCAGGGCCGGCCAGCCGGTGGATATCGAGGTCGATACC
TTCCCGGGCCGCACCTATCACGGCCATGTCGACAGCCTTGCGCCGGCAAGCGGCCAGGAATTCGCCCTGCTGCCGCCCGA
CAATGCGACTGGCAACTTCACCAAGGTCGTTCAACGCATTCCCGTCAAGATCGTCCTGGACGCCGAAGCCGCCAATGGCG
ATCTGCGCCCCGGCATGTCCGTCCAACCGAGCATCGACACCAAGGCCGATGCCGATCGCAAATAA

Upstream 100 bases:

>100_bases
AATACATATTTTGGAAAATATCAAGTTTCCTAAAGCGCATTCCACCTGAATTCGAAGGCCGCGGCCGGTAGCGACAGCGA
CCACTCCAAGGAGAGAGACA

Downstream 100 bases:

>100_bases
GCGCAGGATCGGGAGATTGTCATGTCAAGCATTGCGGCCACCGCTGGGGCCATTGCGCAACCGCGCGCCAGCACAAGGGA
TTGGATCGCCGTCCTCGCCG

Product: multidrug efflux transporter protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 393

Protein sequence:

>394_residues
MSIKTLQALNNNAPAPETTAEAAPATLDAGATPHLVEPAVLSEPPARRRTGRGLLLGATAVVLIAATAYYGHNYWTVGRF
EIATDDAYVKADNTTVAPKVSGYIAEVLVSDNAVVKAGQPLARIDDRDFRAALDQTKADVAAAEATLNAKQASLDIQQST
IAAARATVEVDKANETFAEQNNKRYANLATNGYAPVQTAQQAASTIAAAQATITRDTAALDAAVKQVELLNAELAQARAT
LAHDQAVQHQAELNLSYATITAPVDGTIGNRTLRIGQYVQAGTQLMSVVPTSAVYVIANYKETQLTDVRAGQPVDIEVDT
FPGRTYHGHVDSLAPASGQEFALLPPDNATGNFTKVVQRIPVKIVLDAEAANGDLRPGMSVQPSIDTKADADRK

Sequences:

>Translated_394_residues
MSIKTLQALNNNAPAPETTAEAAPATLDAGATPHLVEPAVLSEPPARRRTGRGLLLGATAVVLIAATAYYGHNYWTVGRF
EIATDDAYVKADNTTVAPKVSGYIAEVLVSDNAVVKAGQPLARIDDRDFRAALDQTKADVAAAEATLNAKQASLDIQQST
IAAARATVEVDKANETFAEQNNKRYANLATNGYAPVQTAQQAASTIAAAQATITRDTAALDAAVKQVELLNAELAQARAT
LAHDQAVQHQAELNLSYATITAPVDGTIGNRTLRIGQYVQAGTQLMSVVPTSAVYVIANYKETQLTDVRAGQPVDIEVDT
FPGRTYHGHVDSLAPASGQEFALLPPDNATGNFTKVVQRIPVKIVLDAEAANGDLRPGMSVQPSIDTKADADRK
>Mature_393_residues
SIKTLQALNNNAPAPETTAEAAPATLDAGATPHLVEPAVLSEPPARRRTGRGLLLGATAVVLIAATAYYGHNYWTVGRFE
IATDDAYVKADNTTVAPKVSGYIAEVLVSDNAVVKAGQPLARIDDRDFRAALDQTKADVAAAEATLNAKQASLDIQQSTI
AAARATVEVDKANETFAEQNNKRYANLATNGYAPVQTAQQAASTIAAAQATITRDTAALDAAVKQVELLNAELAQARATL
AHDQAVQHQAELNLSYATITAPVDGTIGNRTLRIGQYVQAGTQLMSVVPTSAVYVIANYKETQLTDVRAGQPVDIEVDTF
PGRTYHGHVDSLAPASGQEFALLPPDNATGNFTKVVQRIPVKIVLDAEAANGDLRPGMSVQPSIDTKADADRK

Specific function: Unknown

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1788711, Length=351, Percent_Identity=33.6182336182336, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI1790519, Length=290, Percent_Identity=33.7931034482759, Blast_Score=141, Evalue=8e-35,
Organism=Escherichia coli, GI1789041, Length=330, Percent_Identity=33.3333333333333, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI87081951, Length=313, Percent_Identity=29.7124600638978, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1789637, Length=317, Percent_Identity=26.1829652996845, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787013, Length=286, Percent_Identity=31.8181818181818, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1790012, Length=249, Percent_Identity=24.4979919678715, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1790024, Length=252, Percent_Identity=24.2063492063492, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005694
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 41518; Mature: 41387

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIKTLQALNNNAPAPETTAEAAPATLDAGATPHLVEPAVLSEPPARRRTGRGLLLGATA
CCCHHHHHHCCCCCCCCCCHHCCCCEECCCCCCCCCCCHHHCCCCHHHHCCCEEEEHHHH
VVLIAATAYYGHNYWTVGRFEIATDDAYVKADNTTVAPKVSGYIAEVLVSDNAVVKAGQP
HHHHHHHHHHCCCEEEEEEEEEECCCEEEEECCCEECCCHHHHHEEEEECCCEEEECCCC
LARIDDRDFRAALDQTKADVAAAEATLNAKQASLDIQQSTIAAARATVEVDKANETFAEQ
HHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHEEEEEECCCHHHHHC
NNKRYANLATNGYAPVQTAQQAASTIAAAQATITRDTAALDAAVKQVELLNAELAQARAT
CCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAHDQAVQHQAELNLSYATITAPVDGTIGNRTLRIGQYVQAGTQLMSVVPTSAVYVIANY
HHHHHHHHHHHHCEEEEEEEEECCCCCCCCCEEEHHHHHHHHHHHHHHCCCCEEEEEEEC
KETQLTDVRAGQPVDIEVDTFPGRTYHGHVDSLAPASGQEFALLPPDNATGNFTKVVQRI
CCCEEEECCCCCCEEEEEECCCCCEECCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHC
PVKIVLDAEAANGDLRPGMSVQPSIDTKADADRK
CEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SIKTLQALNNNAPAPETTAEAAPATLDAGATPHLVEPAVLSEPPARRRTGRGLLLGATA
CCHHHHHHCCCCCCCCCCHHCCCCEECCCCCCCCCCCHHHCCCCHHHHCCCEEEEHHHH
VVLIAATAYYGHNYWTVGRFEIATDDAYVKADNTTVAPKVSGYIAEVLVSDNAVVKAGQP
HHHHHHHHHHCCCEEEEEEEEEECCCEEEEECCCEECCCHHHHHEEEEECCCEEEECCCC
LARIDDRDFRAALDQTKADVAAAEATLNAKQASLDIQQSTIAAARATVEVDKANETFAEQ
HHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHEEEEEECCCHHHHHC
NNKRYANLATNGYAPVQTAQQAASTIAAAQATITRDTAALDAAVKQVELLNAELAQARAT
CCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAHDQAVQHQAELNLSYATITAPVDGTIGNRTLRIGQYVQAGTQLMSVVPTSAVYVIANY
HHHHHHHHHHHHCEEEEEEEEECCCCCCCCCEEEHHHHHHHHHHHHHHCCCCEEEEEEEC
KETQLTDVRAGQPVDIEVDTFPGRTYHGHVDSLAPASGQEFALLPPDNATGNFTKVVQRI
CCCEEEECCCCCCEEEEEECCCCCEECCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHC
PVKIVLDAEAANGDLRPGMSVQPSIDTKADADRK
CEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]