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The map label for this gene is atzC [H]

Identifier: 189354047

GI number: 189354047

Start: 2374178

End: 2375362

Strand: Reverse

Name: atzC [H]

Synonym: BMULJ_05300

Alternate gene names: 189354047

Gene position: 2375362-2374178 (Counterclockwise)

Preceding gene: 189354048

Following gene: 189354045

Centisome position: 96.05

GC content: 71.81

Gene sequence:

>1185_bases
ATGACCGCCTTGCTGATCCGCAACGTCCGCACGGGCGCCGACGACGCGCTCGACATCCTCATCGAAGGCGATCGCATCGC
GCGCACGGGCCCGTCGCTCGATGCGCCGCCCGGCTGCGCGATCGAGGAAGGCGCCGGTGCAATCGCGCTGCCGGGCCTCG
TCGAAGGCCACACGCATCTCGACAAGACGCACTGGGGCATGCCGTGGTATCGCAACGCGGTCGGCCCGCGCCTCGTCGAT
CGCATCGAGAACGAGCGGCACTATCGCGCGACGAGCGGTCACGATGCCGGCGCGGCATCGCTCGCGCTCGCGCGCGCGTT
CCTCGCGGCCGGCACGACGCGGATCCGCACGCACGTCGACGTCGATACCGATGCGGGGCTGCGTCATCTGCATCGCGTGC
TTGACACGCGCGAGACGTTGCGCGGCCAGGTCGAGATCCAGATCGTCGCGTTTCCGCAGTCGGGCGTGCTGAAGCGGCCC
GGTACCGACGCGCTGCTCGCGGACGCGCTCGCGGCCGGCGCCGATCTGCTCGGCGGCCTCGATCCGTGCGCGATCGAAGG
CGACCCGGTGAAAGCGGTCGACGTGCTGTTCGGGATCGCCGAGCGCTACGGCCGCGGGCTCGACCTTCATCTGCACGAGC
GCGGCTCGATGGGCGCGTATTCGCTCGACCTGATCCTGCAGCGCACGGCCGCGCTCGGCATGCAGCACAAGGTGACGATC
AGCCACGCGTTCTGTCTCGGCGACCTCGCGGAACGCGAGCGCGATGCGCTGCTCGCGCGGATGGCCGAGCTTGGCGTCGC
CGTCGTCACGACCGCGCCGGCCGCGGTGCCGGTGCCGTCGGTCCTCGCGTGCCGCGCGGCCGGCGTGACCGTCATCGGCG
GCAACGACGGCGTGCGCGACACGTGGACGCCGTACGGATCGCCCGACATGCTCGAGCGCGCGATGCTGATCGCGATGCGC
AACGACTTCCGCCGCGACGATGCGCTCGAAGTCGCGCTCGAATGCGTGACGCACGGCGCCGCGCGCGGCTGCGGCTTCGA
CGCTTACGGGCTGCAGCCCGGCGCGCGCGCCGACGTCGTGCTCGTCGATGCGATGACGCTCGCGGAGGCCGTGGTCGCAC
GGCCGGTGCGGCGGCTCGTCGTGTCGTCGGGGAAGATCGTCGCGCGAAACGGCGCGCTGGTCTGA

Upstream 100 bases:

>100_bases
GCGCGATGATGATGCCGATAGCGCGCGCATCGCGCGCCGTCGGCTTGCACTGCGGCCGTTCACACGGCACCGACCTTCAC
ACCGACCGCACGAGATCGAC

Downstream 100 bases:

>100_bases
CCTGCGCACGGCGGTGCGCGGCGGCACGTGTGTGGCCGCACACCGTCCCGCATACCGCGTTGCGGCGCGCGGCTTACTGC
TCGTGTTCGAGCATGTCCGC

Product: cytosine deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 393

Protein sequence:

>394_residues
MTALLIRNVRTGADDALDILIEGDRIARTGPSLDAPPGCAIEEGAGAIALPGLVEGHTHLDKTHWGMPWYRNAVGPRLVD
RIENERHYRATSGHDAGAASLALARAFLAAGTTRIRTHVDVDTDAGLRHLHRVLDTRETLRGQVEIQIVAFPQSGVLKRP
GTDALLADALAAGADLLGGLDPCAIEGDPVKAVDVLFGIAERYGRGLDLHLHERGSMGAYSLDLILQRTAALGMQHKVTI
SHAFCLGDLAERERDALLARMAELGVAVVTTAPAAVPVPSVLACRAAGVTVIGGNDGVRDTWTPYGSPDMLERAMLIAMR
NDFRRDDALEVALECVTHGAARGCGFDAYGLQPGARADVVLVDAMTLAEAVVARPVRRLVVSSGKIVARNGALV

Sequences:

>Translated_394_residues
MTALLIRNVRTGADDALDILIEGDRIARTGPSLDAPPGCAIEEGAGAIALPGLVEGHTHLDKTHWGMPWYRNAVGPRLVD
RIENERHYRATSGHDAGAASLALARAFLAAGTTRIRTHVDVDTDAGLRHLHRVLDTRETLRGQVEIQIVAFPQSGVLKRP
GTDALLADALAAGADLLGGLDPCAIEGDPVKAVDVLFGIAERYGRGLDLHLHERGSMGAYSLDLILQRTAALGMQHKVTI
SHAFCLGDLAERERDALLARMAELGVAVVTTAPAAVPVPSVLACRAAGVTVIGGNDGVRDTWTPYGSPDMLERAMLIAMR
NDFRRDDALEVALECVTHGAARGCGFDAYGLQPGARADVVLVDAMTLAEAVVARPVRRLVVSSGKIVARNGALV
>Mature_393_residues
TALLIRNVRTGADDALDILIEGDRIARTGPSLDAPPGCAIEEGAGAIALPGLVEGHTHLDKTHWGMPWYRNAVGPRLVDR
IENERHYRATSGHDAGAASLALARAFLAAGTTRIRTHVDVDTDAGLRHLHRVLDTRETLRGQVEIQIVAFPQSGVLKRPG
TDALLADALAAGADLLGGLDPCAIEGDPVKAVDVLFGIAERYGRGLDLHLHERGSMGAYSLDLILQRTAALGMQHKVTIS
HAFCLGDLAERERDALLARMAELGVAVVTTAPAAVPVPSVLACRAAGVTVIGGNDGVRDTWTPYGSPDMLERAMLIAMRN
DFRRDDALEVALECVTHGAARGCGFDAYGLQPGARADVVLVDAMTLAEAVVARPVRRLVVSSGKIVARNGALV

Specific function: Transforms N-isopropylammelide to cyanuric acid and isopropylamine [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N-acyl-D-amino-acid deacylase family [H]

Homologues:

Organism=Escherichia coli, GI1786517, Length=350, Percent_Identity=31.7142857142857, Blast_Score=159, Evalue=4e-40,
Organism=Escherichia coli, GI1786531, Length=377, Percent_Identity=27.3209549071618, Blast_Score=117, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013108
- InterPro:   IPR011059 [H]

Pfam domain/function: PF07969 Amidohydro_3 [H]

EC number: =3.5.99.4 [H]

Molecular weight: Translated: 41666; Mature: 41535

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTALLIRNVRTGADDALDILIEGDRIARTGPSLDAPPGCAIEEGAGAIALPGLVEGHTHL
CCEEEEECCCCCCCCEEEEEEECCEEECCCCCCCCCCCCCEECCCCEEECCCCCCCCCCC
DKTHWGMPWYRNAVGPRLVDRIENERHYRATSGHDAGAASLALARAFLAAGTTRIRTHVD
CCCCCCCCHHHHCCCHHHHHHHCCCCCEECCCCCCCHHHHHHHHHHHHHCCCCEEEEEEC
VDTDAGLRHLHRVLDTRETLRGQVEIQIVAFPQSGVLKRPGTDALLADALAAGADLLGGL
CCCCHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCC
DPCAIEGDPVKAVDVLFGIAERYGRGLDLHLHERGSMGAYSLDLILQRTAALGMQHKVTI
CCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEE
SHAFCLGDLAERERDALLARMAELGVAVVTTAPAAVPVPSVLACRAAGVTVIGGNDGVRD
HHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCHHHHHHHCCEEEECCCCCCCC
TWTPYGSPDMLERAMLIAMRNDFRRDDALEVALECVTHGAARGCGFDAYGLQPGARADVV
CCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEE
LVDAMTLAEAVVARPVRRLVVSSGKIVARNGALV
EEHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCC
>Mature Secondary Structure 
TALLIRNVRTGADDALDILIEGDRIARTGPSLDAPPGCAIEEGAGAIALPGLVEGHTHL
CEEEEECCCCCCCCEEEEEEECCEEECCCCCCCCCCCCCEECCCCEEECCCCCCCCCCC
DKTHWGMPWYRNAVGPRLVDRIENERHYRATSGHDAGAASLALARAFLAAGTTRIRTHVD
CCCCCCCCHHHHCCCHHHHHHHCCCCCEECCCCCCCHHHHHHHHHHHHHCCCCEEEEEEC
VDTDAGLRHLHRVLDTRETLRGQVEIQIVAFPQSGVLKRPGTDALLADALAAGADLLGGL
CCCCHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCC
DPCAIEGDPVKAVDVLFGIAERYGRGLDLHLHERGSMGAYSLDLILQRTAALGMQHKVTI
CCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEE
SHAFCLGDLAERERDALLARMAELGVAVVTTAPAAVPVPSVLACRAAGVTVIGGNDGVRD
HHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCHHHHHHHCCEEEECCCCCCCC
TWTPYGSPDMLERAMLIAMRNDFRRDDALEVALECVTHGAARGCGFDAYGLQPGARADVV
CCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEE
LVDAMTLAEAVVARPVRRLVVSSGKIVARNGALV
EEHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9422605 [H]