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The map label for this gene is atzC [H]

Identifier: 189354048

GI number: 189354048

Start: 2375454

End: 2376653

Strand: Reverse

Name: atzC [H]

Synonym: BMULJ_05301

Alternate gene names: 189354048

Gene position: 2376653-2375454 (Counterclockwise)

Preceding gene: 189354051

Following gene: 189354047

Centisome position: 96.1

GC content: 72.42

Gene sequence:

>1200_bases
ATGACCGACCGCCTCTTCACCCATGCCGTCGACGCCGACGGCCAGCCCCTCGAACTGCTCGTGCGCGACGGCCGTTTCGT
CGCGATCGGCCGCGACTGCGGCGCCGCGTCCGGCACGGAAACGATCGATCTCGACGGCCGCGTCGTATTACCCGGCTTCG
TCGACGGCCACATTCATCTGGACAAAAGCTTCGTCGGCGGCCGCTGGGTGCCGCACGAACCGGTCGACTCGCTGCGCGCG
CGGCTCGCGGTCGAGAAGCGTCAGCTCGCCGCCGCGCCGCCGATCGCCGAGCGCGCGCATGCACTGATCGCGCAGGCCGC
CGCATTCGGCACGGTCGCGATGCGCAGCCATGTCGACGTCGACGCGACGACGGGCCTCGCGAACCTGCACGCGGTGATGG
CCGCGCGCGAACGGTGGCGCGGCATCGTCGACATCGAGCTCGTCGCGTTTCCGCAGGCCGGCGTCGTGTCGTGCGCGGGC
ACGGCCGAGATGCTCGACGCGGCCGTGCGCGAAGGCGCGGACGTCGTCGGCGGCATCGATCCGACGACGCTCGACGGCGA
TGCGGACGGCCAGCTCGACATCGTGTTCGGCATTGCCGAGAAGCGCGGCGTGAAGATCGACATTCATCTGCACGAGCCGG
GCGACACGGGCATCGCACAACTGCTGCGGATCGCGGCGCGCACGCGTGCGGCCGGCCTCGGCGGGCGCGTGAACGTGAGC
CACGCGTATGCGCTCGGCCAGGTCGGCGCCGACGTCGTCGCGCGCACCGCGGCCGCGCTGGCCGACGCCGGCGTGTCGAT
CATGACGAACGCGCCGGGCGACTGCGCGTTTCCGCCGGTGCTGGCGTTGCGCGATGCGGGCGTGCACGTGTTCGCCGGCA
ACGACAACATTCGCGACGCGTGGTGGCCGTACGGCAACGGCGACATGCTGCAGCGCGCGATGCTGATCGGCTATCGGTCG
GGCTTCTACACCGACGACGCGCTGCGCGTCGCGCTCGACATGGCGACGCACGCAGGCGCACGCGCCATCGGCCGCACACA
CTACGGGCTCGCGGTCGGCTGCGACGCAACCTTCGTCGCGGTGCGCGCGCCGAATGCGGCGGCGGCCGTCGCCGGCGTGC
CGGCCGAGCGCTGGGTCGTGCGTCGCGGCGAAAGCGACCGCGGCGCGCCGTACGCGCCCGCGCTCGATTTCGCGCGATGA

Upstream 100 bases:

>100_bases
CCGCTATCGTGGCCGCACCCCATTCACGGTCGCGCCGCACCGGTCCGACGTTTGCCGTTCGCCCCGGCGTCGCGCCGCGA
CCTTCGCCCTATCACGAACG

Downstream 100 bases:

>100_bases
TGATGCCGATAGCGCGCGCATCGCGCGCCGTCGGCTTGCACTGCGGCCGTTCACACGGCACCGACCTTCACACCGACCGC
ACGAGATCGACATGACCGCC

Product: cytosine deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 398

Protein sequence:

>399_residues
MTDRLFTHAVDADGQPLELLVRDGRFVAIGRDCGAASGTETIDLDGRVVLPGFVDGHIHLDKSFVGGRWVPHEPVDSLRA
RLAVEKRQLAAAPPIAERAHALIAQAAAFGTVAMRSHVDVDATTGLANLHAVMAARERWRGIVDIELVAFPQAGVVSCAG
TAEMLDAAVREGADVVGGIDPTTLDGDADGQLDIVFGIAEKRGVKIDIHLHEPGDTGIAQLLRIAARTRAAGLGGRVNVS
HAYALGQVGADVVARTAAALADAGVSIMTNAPGDCAFPPVLALRDAGVHVFAGNDNIRDAWWPYGNGDMLQRAMLIGYRS
GFYTDDALRVALDMATHAGARAIGRTHYGLAVGCDATFVAVRAPNAAAAVAGVPAERWVVRRGESDRGAPYAPALDFAR

Sequences:

>Translated_399_residues
MTDRLFTHAVDADGQPLELLVRDGRFVAIGRDCGAASGTETIDLDGRVVLPGFVDGHIHLDKSFVGGRWVPHEPVDSLRA
RLAVEKRQLAAAPPIAERAHALIAQAAAFGTVAMRSHVDVDATTGLANLHAVMAARERWRGIVDIELVAFPQAGVVSCAG
TAEMLDAAVREGADVVGGIDPTTLDGDADGQLDIVFGIAEKRGVKIDIHLHEPGDTGIAQLLRIAARTRAAGLGGRVNVS
HAYALGQVGADVVARTAAALADAGVSIMTNAPGDCAFPPVLALRDAGVHVFAGNDNIRDAWWPYGNGDMLQRAMLIGYRS
GFYTDDALRVALDMATHAGARAIGRTHYGLAVGCDATFVAVRAPNAAAAVAGVPAERWVVRRGESDRGAPYAPALDFAR
>Mature_398_residues
TDRLFTHAVDADGQPLELLVRDGRFVAIGRDCGAASGTETIDLDGRVVLPGFVDGHIHLDKSFVGGRWVPHEPVDSLRAR
LAVEKRQLAAAPPIAERAHALIAQAAAFGTVAMRSHVDVDATTGLANLHAVMAARERWRGIVDIELVAFPQAGVVSCAGT
AEMLDAAVREGADVVGGIDPTTLDGDADGQLDIVFGIAEKRGVKIDIHLHEPGDTGIAQLLRIAARTRAAGLGGRVNVSH
AYALGQVGADVVARTAAALADAGVSIMTNAPGDCAFPPVLALRDAGVHVFAGNDNIRDAWWPYGNGDMLQRAMLIGYRSG
FYTDDALRVALDMATHAGARAIGRTHYGLAVGCDATFVAVRAPNAAAAVAGVPAERWVVRRGESDRGAPYAPALDFAR

Specific function: Transforms N-isopropylammelide to cyanuric acid and isopropylamine [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N-acyl-D-amino-acid deacylase family [H]

Homologues:

Organism=Escherichia coli, GI1786517, Length=376, Percent_Identity=31.6489361702128, Blast_Score=175, Evalue=6e-45,
Organism=Escherichia coli, GI1786531, Length=391, Percent_Identity=28.3887468030691, Blast_Score=136, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013108
- InterPro:   IPR011059 [H]

Pfam domain/function: PF07969 Amidohydro_3 [H]

EC number: =3.5.99.4 [H]

Molecular weight: Translated: 41757; Mature: 41626

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDRLFTHAVDADGQPLELLVRDGRFVAIGRDCGAASGTETIDLDGRVVLPGFVDGHIHL
CCCCEEEEEECCCCCCEEEEEECCEEEEEECCCCCCCCCEEEECCCEEEECCEECCEEEE
DKSFVGGRWVPHEPVDSLRARLAVEKRQLAAAPPIAERAHALIAQAAAFGTVAMRSHVDV
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
DATTGLANLHAVMAARERWRGIVDIELVAFPQAGVVSCAGTAEMLDAAVREGADVVGGID
CCCCCHHHHHHHHHHHHHCCCEEEEEEEEECCCCEEEECCHHHHHHHHHHCCCCEECCCC
PTTLDGDADGQLDIVFGIAEKRGVKIDIHLHEPGDTGIAQLLRIAARTRAAGLGGRVNVS
CCCCCCCCCCCEEEEEEECCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEEH
HAYALGQVGADVVARTAAALADAGVSIMTNAPGDCAFPPVLALRDAGVHVFAGNDNIRDA
HHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCHHEEECCCEEEEECCCCCCCC
WWPYGNGDMLQRAMLIGYRSGFYTDDALRVALDMATHAGARAIGRTHYGLAVGCDATFVA
CCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHCCCCCCEEEECCCEEEE
VRAPNAAAAVAGVPAERWVVRRGESDRGAPYAPALDFAR
EECCCCHHHCCCCCHHHHHEECCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TDRLFTHAVDADGQPLELLVRDGRFVAIGRDCGAASGTETIDLDGRVVLPGFVDGHIHL
CCCEEEEEECCCCCCEEEEEECCEEEEEECCCCCCCCCEEEECCCEEEECCEECCEEEE
DKSFVGGRWVPHEPVDSLRARLAVEKRQLAAAPPIAERAHALIAQAAAFGTVAMRSHVDV
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
DATTGLANLHAVMAARERWRGIVDIELVAFPQAGVVSCAGTAEMLDAAVREGADVVGGID
CCCCCHHHHHHHHHHHHHCCCEEEEEEEEECCCCEEEECCHHHHHHHHHHCCCCEECCCC
PTTLDGDADGQLDIVFGIAEKRGVKIDIHLHEPGDTGIAQLLRIAARTRAAGLGGRVNVS
CCCCCCCCCCCEEEEEEECCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEEH
HAYALGQVGADVVARTAAALADAGVSIMTNAPGDCAFPPVLALRDAGVHVFAGNDNIRDA
HHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCHHEEECCCEEEEECCCCCCCC
WWPYGNGDMLQRAMLIGYRSGFYTDDALRVALDMATHAGARAIGRTHYGLAVGCDATFVA
CCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHCCCCCCEEEECCCEEEE
VRAPNAAAAVAGVPAERWVVRRGESDRGAPYAPALDFAR
EECCCCHHHCCCCCHHHHHEECCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9422605 [H]