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The map label for this gene is fruR1 [H]

Identifier: 189353714

GI number: 189353714

Start: 1978569

End: 1979633

Strand: Direct

Name: fruR1 [H]

Synonym: BMULJ_04959

Alternate gene names: 189353714

Gene position: 1978569-1979633 (Clockwise)

Preceding gene: 189353707

Following gene: 189353727

Centisome position: 80.0

GC content: 67.89

Gene sequence:

>1065_bases
ATGGCCCGCCACACCACCGGACGCAAGTCCACGATTTACGACATCGCAAAAACGACCGGCGCATCGACGTCGACCGTCAG
CATGGTGCTGAACGGCACGTGGGCGCGCTACCGGATCAAGGAAGAAACGGCGAACCGCATCCTCGCGTGCGCAGAGGCGC
TCGGCTACAACGTGAACCTGAGTGCGCGCGGCCTGCGGCTGTCGCGCTCGGGGCTGGCCGGCATGATCATCCCGCACTAT
CGCAACCGCTTCTTCGCGGGGCTGGCCGAAACGTTCGAGGACGAGGCACGTCGCCGCGGCCTGTGCCCGATCGTTGTGGG
CACGCAGCGCGATCCGGCCGTCGAATCGAGCGTCACGCAAACGTTGCTTGCACAACGAGTCGAATGGCTGTTCGTTGCCG
GCGTGCGCGATCCCGCGCCGCTGAACGCACTGTGCGACAAGGCCGGCGTACCGTCGATCAATCTCGATCTGCCCGGCCCC
GGCGCGCCGTCGATCGTATCGGACAACCGCGGCGGCGCTCGCGCGCTAGCCGACCGACTCATCGACAAGATGCTCGCGCG
CGGCGAGTCACCCGCGGAGCTGATCCTGCTCGGCGGGTTCGCCGGCGAGTACGCGACGGAGATGCGCATCGCCGGATTCC
GCGACGCATTCGAAGCCCGACGCCTGACGCCGCCGGCCGCCGACGCGATCGAATGCTGCGGCTATAGCCCCGACGCGGCG
CGACAGGCGCTCGCGCGACGTTATGCGGCGCTCGGCCGGCTGCCGGCCGGCATGCTGATGAATTCGATCACGGCGTTCGA
AGGGCTCGTCCGCTTCGCGTCCGGGTTGCCGTGGGACATCTGGCAGCGCACGGCCGTCGGCTGTTTCGACTGGGATCCGT
TCGCCGCGCGGTTGCCGTTCGATGTGACGATGCTGCGTCAGGACGTGCAGAAAATGATCGCGGAAGCGTTCGCGCTGCTC
GATGCGCCGGACACGACGCCGCATCCGACCGTCATGGTACCGACCCGCTTCATGGACACGCTGGACGACGACACGACCGC
GCCGGACGACGCGCGTGCCGACTGA

Upstream 100 bases:

>100_bases
GCTTCGTTGAGAAGCGCGGGAAAACCCGAATAGGGCGGCGCGGCGTAAAACGAATACCGTCGGGTGACCGATAAGAACGA
CGCCAGGGAAACCGACGCAG

Downstream 100 bases:

>100_bases
ACGTCATGCGCGATAGACCGGCCGCCAAATGACGAAAGCCCGACGGCATGGGCCGACCGGGCTTCGTTGCGGCTAGCGTG
GCGTTGCGACGATCGCGACC

Product: LacI family fructose operon transcriptional repressor

Products: NA

Alternate protein names: Rbt operon repressor [H]

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MARHTTGRKSTIYDIAKTTGASTSTVSMVLNGTWARYRIKEETANRILACAEALGYNVNLSARGLRLSRSGLAGMIIPHY
RNRFFAGLAETFEDEARRRGLCPIVVGTQRDPAVESSVTQTLLAQRVEWLFVAGVRDPAPLNALCDKAGVPSINLDLPGP
GAPSIVSDNRGGARALADRLIDKMLARGESPAELILLGGFAGEYATEMRIAGFRDAFEARRLTPPAADAIECCGYSPDAA
RQALARRYAALGRLPAGMLMNSITAFEGLVRFASGLPWDIWQRTAVGCFDWDPFAARLPFDVTMLRQDVQKMIAEAFALL
DAPDTTPHPTVMVPTRFMDTLDDDTTAPDDARAD

Sequences:

>Translated_354_residues
MARHTTGRKSTIYDIAKTTGASTSTVSMVLNGTWARYRIKEETANRILACAEALGYNVNLSARGLRLSRSGLAGMIIPHY
RNRFFAGLAETFEDEARRRGLCPIVVGTQRDPAVESSVTQTLLAQRVEWLFVAGVRDPAPLNALCDKAGVPSINLDLPGP
GAPSIVSDNRGGARALADRLIDKMLARGESPAELILLGGFAGEYATEMRIAGFRDAFEARRLTPPAADAIECCGYSPDAA
RQALARRYAALGRLPAGMLMNSITAFEGLVRFASGLPWDIWQRTAVGCFDWDPFAARLPFDVTMLRQDVQKMIAEAFALL
DAPDTTPHPTVMVPTRFMDTLDDDTTAPDDARAD
>Mature_353_residues
ARHTTGRKSTIYDIAKTTGASTSTVSMVLNGTWARYRIKEETANRILACAEALGYNVNLSARGLRLSRSGLAGMIIPHYR
NRFFAGLAETFEDEARRRGLCPIVVGTQRDPAVESSVTQTLLAQRVEWLFVAGVRDPAPLNALCDKAGVPSINLDLPGPG
APSIVSDNRGGARALADRLIDKMLARGESPAELILLGGFAGEYATEMRIAGFRDAFEARRLTPPAADAIECCGYSPDAAR
QALARRYAALGRLPAGMLMNSITAFEGLVRFASGLPWDIWQRTAVGCFDWDPFAARLPFDVTMLRQDVQKMIAEAFALLD
APDTTPHPTVMVPTRFMDTLDDDTTAPDDARAD

Specific function: Repressor for the genes of the ribitol operon. Binds D- ribulose as an inducer [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786268, Length=275, Percent_Identity=26.1818181818182, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1790194, Length=246, Percent_Identity=27.6422764227642, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787906, Length=218, Percent_Identity=27.0642201834862, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 38423; Mature: 38292

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARHTTGRKSTIYDIAKTTGASTSTVSMVLNGTWARYRIKEETANRILACAEALGYNVNL
CCCCCCCCCHHHHHHHHHCCCCCCEEEEEEECCHHEEEEHHHHHHHHHHHHHHHCCCCCC
SARGLRLSRSGLAGMIIPHYRNRFFAGLAETFEDEARRRGLCPIVVGTQRDPAVESSVTQ
CCCCCEEECCCCCCEECHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHH
TLLAQRVEWLFVAGVRDPAPLNALCDKAGVPSINLDLPGPGAPSIVSDNRGGARALADRL
HHHHHHHHEEEEECCCCCCCHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHH
IDKMLARGESPAELILLGGFAGEYATEMRIAGFRDAFEARRLTPPAADAIECCGYSPDAA
HHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHH
RQALARRYAALGRLPAGMLMNSITAFEGLVRFASGLPWDIWQRTAVGCFDWDPFAARLPF
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCHHCCCC
DVTMLRQDVQKMIAEAFALLDAPDTTPHPTVMVPTRFMDTLDDDTTAPDDARAD
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
ARHTTGRKSTIYDIAKTTGASTSTVSMVLNGTWARYRIKEETANRILACAEALGYNVNL
CCCCCCCCHHHHHHHHHCCCCCCEEEEEEECCHHEEEEHHHHHHHHHHHHHHHCCCCCC
SARGLRLSRSGLAGMIIPHYRNRFFAGLAETFEDEARRRGLCPIVVGTQRDPAVESSVTQ
CCCCCEEECCCCCCEECHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHH
TLLAQRVEWLFVAGVRDPAPLNALCDKAGVPSINLDLPGPGAPSIVSDNRGGARALADRL
HHHHHHHHEEEEECCCCCCCHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHH
IDKMLARGESPAELILLGGFAGEYATEMRIAGFRDAFEARRLTPPAADAIECCGYSPDAA
HHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHH
RQALARRYAALGRLPAGMLMNSITAFEGLVRFASGLPWDIWQRTAVGCFDWDPFAARLPF
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCHHCCCC
DVTMLRQDVQKMIAEAFALLDAPDTTPHPTVMVPTRFMDTLDDDTTAPDDARAD
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3891331 [H]