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The map label for this gene is qseC [H]

Identifier: 189353583

GI number: 189353583

Start: 1832949

End: 1834319

Strand: Direct

Name: qseC [H]

Synonym: BMULJ_04827

Alternate gene names: 189353583

Gene position: 1832949-1834319 (Clockwise)

Preceding gene: 189353582

Following gene: 189353585

Centisome position: 74.11

GC content: 71.33

Gene sequence:

>1371_bases
ATGACGCGCCTGCAACGCGCGATCGCGCGCTGGCGCGGCGTGTCGCTGCGGCGGCGCCTGCTGATCTGGCTGCTGCCGGC
CGCATGCGTGATCGGGCTCGCGGCGAGCGCGGGCACGTACTGGGGCGCGCTGCGCGAGCTCGACGATCTGCTCGACGATC
AGATGCGCAGCATGTCGAAACAAATCGTCGTCGGGCCGAACGGCGAGCTGTCGTTCCGCAACCGCGGCGACGACAAGCAC
GCGTTCAAGGCCGACGACCCCGACGCCGTGCTGCTGCAGGTCTGGCGCAACGGCACGCTCGTCTATACGACCGATCGCGA
CGTCGCGTTGCCGCCGCCCGCGCATGCGGGTACCGCGAGCGTCGACGTCGACGGCCAGCCGTGGCGCACCTACGTGACGC
AGCGCGGCGGCACGACGATCCGGCTCGCGCAGGCGCGCCACGCGCGCTGGGAGGCGATCGCCGGCATTGCCGTGCATCTG
CTGTGGCCGCTGTTCTCGATGCTGCCGGTACTCGCGATCGGGCTGTGGTTCGGCATCGGCGCCGGGCTGCGGCCGCTGCG
CACGATCGCGGCCGGCCTCCGGCGCCGAAATGCCGGCAATCTCGAACCGGTCGACGTCGCGGCGATGCCGAACGAAGTCC
GTCCGCTTGCCGAAGCGATCAACGACCTGCTCGCGCGGCTCGACCGCTCGTTCACGCTGCAGCGGCACTTCATCGCCGAT
GCCGCGCACGAGCTGCGCACACCGATCATGGGCCTGTCGATCCAGTCACAGCTGCTTCGGCGTGCGGCCACGGCCGACGA
GCGCGAGCGGATTCTCGCGCAGATCCATGCGGGGACGACGCGTCTCGGCCATCTCGCCGAGCAGTTGCTGACGCTCGCGC
GCGTCGAACCCGACGCACAGACGGCCGCCTTCGCGCCGGTCGATCTCGCGGCGCTGTGCCGGTCGGTCGTCGCCGATCGC
GCGCGCGTCGCCGACGCGCACCGCATCGATCTCGGCGCGATCGTGTCGTCGCCCGTGATCGCCGCCGGCCATGCCGACAC
GCTGCGCGTGCTGCTGAACAACCTCGTCGACAACGCGATCCGCTATGCGGGCGACGGCGCGCGCGTCGACGTGTGCGCGC
GCAACGACGGCACGACCCCCGTGCTCGAGGTCGCCGACGACGGCCCCGGCATTCCGGAAGCCGAACGCGCACACGTATGG
GAGCGCTTCTATCGCGGCGAAGGCGCGCAGGCCGCGACGTCGTCGGGCAGCGGGCTCGGCCTGTCGATCGTGAAGCGGAT
CGCGGAACAGCATCGCGCGACGGTCGCGCTCGCCACGACGCGCGGCGGACGCGGACTCACCGTATCGGTACGTTTTCCCG
ATCCGTCCTGA

Upstream 100 bases:

>100_bases
GCAACGCCGTGCAGGTGCACATCCACAACCTGCGCAAGAAACTCGGCCACGACATGATCCGCACGGTGCGCGGCGTCGGC
TACCGGATCGGTGACGGCAC

Downstream 100 bases:

>100_bases
CGGCTTGTCCACAGATTTTGTTGGCAAGCTTGTGGATATCCTGCGCATCGCGCCGCTAAGCCCTTGATCCGACGGACATT
GGCACGCGTGATGCAGACGC

Product: signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 455

Protein sequence:

>456_residues
MTRLQRAIARWRGVSLRRRLLIWLLPAACVIGLAASAGTYWGALRELDDLLDDQMRSMSKQIVVGPNGELSFRNRGDDKH
AFKADDPDAVLLQVWRNGTLVYTTDRDVALPPPAHAGTASVDVDGQPWRTYVTQRGGTTIRLAQARHARWEAIAGIAVHL
LWPLFSMLPVLAIGLWFGIGAGLRPLRTIAAGLRRRNAGNLEPVDVAAMPNEVRPLAEAINDLLARLDRSFTLQRHFIAD
AAHELRTPIMGLSIQSQLLRRAATADERERILAQIHAGTTRLGHLAEQLLTLARVEPDAQTAAFAPVDLAALCRSVVADR
ARVADAHRIDLGAIVSSPVIAAGHADTLRVLLNNLVDNAIRYAGDGARVDVCARNDGTTPVLEVADDGPGIPEAERAHVW
ERFYRGEGAQAATSSGSGLGLSIVKRIAEQHRATVALATTRGGRGLTVSVRFPDPS

Sequences:

>Translated_456_residues
MTRLQRAIARWRGVSLRRRLLIWLLPAACVIGLAASAGTYWGALRELDDLLDDQMRSMSKQIVVGPNGELSFRNRGDDKH
AFKADDPDAVLLQVWRNGTLVYTTDRDVALPPPAHAGTASVDVDGQPWRTYVTQRGGTTIRLAQARHARWEAIAGIAVHL
LWPLFSMLPVLAIGLWFGIGAGLRPLRTIAAGLRRRNAGNLEPVDVAAMPNEVRPLAEAINDLLARLDRSFTLQRHFIAD
AAHELRTPIMGLSIQSQLLRRAATADERERILAQIHAGTTRLGHLAEQLLTLARVEPDAQTAAFAPVDLAALCRSVVADR
ARVADAHRIDLGAIVSSPVIAAGHADTLRVLLNNLVDNAIRYAGDGARVDVCARNDGTTPVLEVADDGPGIPEAERAHVW
ERFYRGEGAQAATSSGSGLGLSIVKRIAEQHRATVALATTRGGRGLTVSVRFPDPS
>Mature_455_residues
TRLQRAIARWRGVSLRRRLLIWLLPAACVIGLAASAGTYWGALRELDDLLDDQMRSMSKQIVVGPNGELSFRNRGDDKHA
FKADDPDAVLLQVWRNGTLVYTTDRDVALPPPAHAGTASVDVDGQPWRTYVTQRGGTTIRLAQARHARWEAIAGIAVHLL
WPLFSMLPVLAIGLWFGIGAGLRPLRTIAAGLRRRNAGNLEPVDVAAMPNEVRPLAEAINDLLARLDRSFTLQRHFIADA
AHELRTPIMGLSIQSQLLRRAATADERERILAQIHAGTTRLGHLAEQLLTLARVEPDAQTAAFAPVDLAALCRSVVADRA
RVADAHRIDLGAIVSSPVIAAGHADTLRVLLNNLVDNAIRYAGDGARVDVCARNDGTTPVLEVADDGPGIPEAERAHVWE
RFYRGEGAQAATSSGSGLGLSIVKRIAEQHRATVALATTRGGRGLTVSVRFPDPS

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. May activate qseB by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=448, Percent_Identity=31.4732142857143, Blast_Score=169, Evalue=5e-43,
Organism=Escherichia coli, GI1788393, Length=272, Percent_Identity=30.1470588235294, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1788279, Length=297, Percent_Identity=29.2929292929293, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1790551, Length=304, Percent_Identity=29.2763157894737, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1786783, Length=294, Percent_Identity=28.2312925170068, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1790346, Length=275, Percent_Identity=30.1818181818182, Blast_Score=101, Evalue=9e-23,
Organism=Escherichia coli, GI1786600, Length=222, Percent_Identity=29.7297297297297, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1790861, Length=242, Percent_Identity=29.7520661157025, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1787894, Length=457, Percent_Identity=25.601750547046, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1789808, Length=301, Percent_Identity=28.2392026578073, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI48994928, Length=234, Percent_Identity=26.9230769230769, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87082128, Length=345, Percent_Identity=25.7971014492754, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1787374, Length=278, Percent_Identity=24.1007194244604, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI145693157, Length=244, Percent_Identity=22.9508196721311, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1786912, Length=226, Percent_Identity=27.4336283185841, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1790436, Length=239, Percent_Identity=28.0334728033473, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789149, Length=206, Percent_Identity=24.7572815533981, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI87081816, Length=222, Percent_Identity=26.5765765765766, Blast_Score=62, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 49358; Mature: 49227

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRLQRAIARWRGVSLRRRLLIWLLPAACVIGLAASAGTYWGALRELDDLLDDQMRSMSK
CCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCC
QIVVGPNGELSFRNRGDDKHAFKADDPDAVLLQVWRNGTLVYTTDRDVALPPPAHAGTAS
EEEECCCCCEEECCCCCCCCCCCCCCCCHHHHHHHCCCEEEEECCCCCCCCCCCCCCCEE
VDVDGQPWRTYVTQRGGTTIRLAQARHARWEAIAGIAVHLLWPLFSMLPVLAIGLWFGIG
EECCCCCHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AGLRPLRTIAAGLRRRNAGNLEPVDVAAMPNEVRPLAEAINDLLARLDRSFTLQRHFIAD
CCHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAHELRTPIMGLSIQSQLLRRAATADERERILAQIHAGTTRLGHLAEQLLTLARVEPDAQ
HHHHHHCCHHCHHHHHHHHHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCH
TAAFAPVDLAALCRSVVADRARVADAHRIDLGAIVSSPVIAAGHADTLRVLLNNLVDNAI
HHCCCCHHHHHHHHHHHHHHHHHCCHHHCCHHHHHCCCEEECCCHHHHHHHHHHHHHHHH
RYAGDGARVDVCARNDGTTPVLEVADDGPGIPEAERAHVWERFYRGEGAQAATSSGSGLG
HHCCCCCEEEEEECCCCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCH
LSIVKRIAEQHRATVALATTRGGRGLTVSVRFPDPS
HHHHHHHHHHHHCEEEEEEECCCCEEEEEEECCCCC
>Mature Secondary Structure 
TRLQRAIARWRGVSLRRRLLIWLLPAACVIGLAASAGTYWGALRELDDLLDDQMRSMSK
CHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCC
QIVVGPNGELSFRNRGDDKHAFKADDPDAVLLQVWRNGTLVYTTDRDVALPPPAHAGTAS
EEEECCCCCEEECCCCCCCCCCCCCCCCHHHHHHHCCCEEEEECCCCCCCCCCCCCCCEE
VDVDGQPWRTYVTQRGGTTIRLAQARHARWEAIAGIAVHLLWPLFSMLPVLAIGLWFGIG
EECCCCCHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AGLRPLRTIAAGLRRRNAGNLEPVDVAAMPNEVRPLAEAINDLLARLDRSFTLQRHFIAD
CCHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAHELRTPIMGLSIQSQLLRRAATADERERILAQIHAGTTRLGHLAEQLLTLARVEPDAQ
HHHHHHCCHHCHHHHHHHHHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCH
TAAFAPVDLAALCRSVVADRARVADAHRIDLGAIVSSPVIAAGHADTLRVLLNNLVDNAI
HHCCCCHHHHHHHHHHHHHHHHHCCHHHCCHHHHHCCCEEECCCHHHHHHHHHHHHHHHH
RYAGDGARVDVCARNDGTTPVLEVADDGPGIPEAERAHVWERFYRGEGAQAATSSGSGLG
HHCCCCCEEEEEECCCCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCH
LSIVKRIAEQHRATVALATTRGGRGLTVSVRFPDPS
HHHHHHHHHHHHCEEEEEEECCCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796; 11929534 [H]