Click here to switch to the map view.

The map label for this gene is penR [H]

Identifier: 189353585

GI number: 189353585

Start: 1835969

End: 1836871

Strand: Direct

Name: penR [H]

Synonym: BMULJ_04829

Alternate gene names: 189353585

Gene position: 1835969-1836871 (Clockwise)

Preceding gene: 189353583

Following gene: 189353589

Centisome position: 74.24

GC content: 68.66

Gene sequence:

>903_bases
ATGGCCAAGCTCCGCCCTCACCTTCCGCTCAATGCCCTGCGCGCGTTCGAATCGTCGGCGCGCCATCTGAACTTCACGCG
CGCGGGCCTCGAGCTGAGCGTCACGCAGGCGGCAGTCAGCCAGCAGGTACGCGCGCTCGAAGAACGGCTCGGCTGCGCAT
TGTTCACGCGTTTGCCGCGCGGGCTCGATCTGACGGACGAAGGCCGCGCGCTGCTGCCCGTGCTCAGCGATGCGTTCAGC
CGCATCGAGACGGTGCTCCAGCAGTTCGACGGCGGGCGGCTGCGGCAGGTGCTCACGCTCGGTGTCGTCGGCACCTTTGC
CCTAGGCTGGCTAATGCCGAGACTGAAGCGCTTCCGCGATACGCACCCGTTCGTCGAGCTGCGGCTGCGCACGCACAACA
ACGTCGTCGACCTCGCCGCCGAAGGGCTCGACTTCGCGATCCGCTTCGGCCAGGGCAACTGGCCGGCCACGCGCAACGAG
CGGCTGTTCGACGCGCCGCTCACGGCGCTGTGCGCACCCGAGATCGCGCGCCGCCTCACGCAGCCGGCCGATCTCGCGCA
CGAAACGCTGCTGCGCTCGTACCGCACGGACGAGTGGCTCGGCTGGTTCGACGCCGCGCAGCTCGAACCGTGGACCGTCA
ACGGGCCGGTGTTCGATTCGTCGCGGCTGATGGTCGAAGCGGCGATGCAGGGCATGGGCATTGCGCTCGCGCCGGCCTGC
ATGTTCGAACGCGAACTGCAGCTCGGCCTGCTTGCGCGGCCGCTCGACATCGACGTGCACGCGGGCGGCTACTGGCTCAC
GTCGCTGAAGTCGAAATCGCTGACACCCGCGATGACGCTGTTTCGCGACTGGATTACGGCCGAGGCATCGGCGGCCGCCT
CAGCAGCTGCGGATGCCGACTGA

Upstream 100 bases:

>100_bases
GCGAAACGAATGCGGAACGCCGGCCGGCGAGACAGCACTATCGTCACTTTACGGTTACCCGACAAGCAACGATAATTGAG
CGCTGACAAAAGAAAACCTT

Downstream 100 bases:

>100_bases
GCGACGCGCCGCTTGTCCACAGATTTTGTTGGCAAGGATGTGGATATCCTGGGTATCCGGACGCTAAGCCCTTGATCGCG
CACGATTTACGGCGCCGACG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MAKLRPHLPLNALRAFESSARHLNFTRAGLELSVTQAAVSQQVRALEERLGCALFTRLPRGLDLTDEGRALLPVLSDAFS
RIETVLQQFDGGRLRQVLTLGVVGTFALGWLMPRLKRFRDTHPFVELRLRTHNNVVDLAAEGLDFAIRFGQGNWPATRNE
RLFDAPLTALCAPEIARRLTQPADLAHETLLRSYRTDEWLGWFDAAQLEPWTVNGPVFDSSRLMVEAAMQGMGIALAPAC
MFERELQLGLLARPLDIDVHAGGYWLTSLKSKSLTPAMTLFRDWITAEASAAASAAADAD

Sequences:

>Translated_300_residues
MAKLRPHLPLNALRAFESSARHLNFTRAGLELSVTQAAVSQQVRALEERLGCALFTRLPRGLDLTDEGRALLPVLSDAFS
RIETVLQQFDGGRLRQVLTLGVVGTFALGWLMPRLKRFRDTHPFVELRLRTHNNVVDLAAEGLDFAIRFGQGNWPATRNE
RLFDAPLTALCAPEIARRLTQPADLAHETLLRSYRTDEWLGWFDAAQLEPWTVNGPVFDSSRLMVEAAMQGMGIALAPAC
MFERELQLGLLARPLDIDVHAGGYWLTSLKSKSLTPAMTLFRDWITAEASAAASAAADAD
>Mature_299_residues
AKLRPHLPLNALRAFESSARHLNFTRAGLELSVTQAAVSQQVRALEERLGCALFTRLPRGLDLTDEGRALLPVLSDAFSR
IETVLQQFDGGRLRQVLTLGVVGTFALGWLMPRLKRFRDTHPFVELRLRTHNNVVDLAAEGLDFAIRFGQGNWPATRNER
LFDAPLTALCAPEIARRLTQPADLAHETLLRSYRTDEWLGWFDAAQLEPWTVNGPVFDSSRLMVEAAMQGMGIALAPACM
FERELQLGLLARPLDIDVHAGGYWLTSLKSKSLTPAMTLFRDWITAEASAAASAAADAD

Specific function: This protein is a positive regulator of gene expression of beta-lactamase (AmpC) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789173, Length=296, Percent_Identity=36.8243243243243, Blast_Score=191, Evalue=6e-50,
Organism=Escherichia coli, GI1786448, Length=290, Percent_Identity=32.4137931034483, Blast_Score=144, Evalue=7e-36,
Organism=Escherichia coli, GI1788706, Length=296, Percent_Identity=31.0810810810811, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1786401, Length=259, Percent_Identity=26.6409266409266, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1787589, Length=291, Percent_Identity=26.1168384879725, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1787128, Length=280, Percent_Identity=25.7142857142857, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI145693193, Length=300, Percent_Identity=27.3333333333333, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1790262, Length=234, Percent_Identity=27.3504273504274, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33232; Mature: 33100

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKLRPHLPLNALRAFESSARHLNFTRAGLELSVTQAAVSQQVRALEERLGCALFTRLPR
CCCCCCCCCHHHHHHHHHHHHHCEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GLDLTDEGRALLPVLSDAFSRIETVLQQFDGGRLRQVLTLGVVGTFALGWLMPRLKRFRD
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
THPFVELRLRTHNNVVDLAAEGLDFAIRFGQGNWPATRNERLFDAPLTALCAPEIARRLT
CCCEEEEEEECCCCCHHHHHCCCEEEEEECCCCCCCCCCCEEECCCHHHHHHHHHHHHHC
QPADLAHETLLRSYRTDEWLGWFDAAQLEPWTVNGPVFDSSRLMVEAAMQGMGIALAPAC
CHHHHHHHHHHHHHCCCHHHCHHCCCCCCCEECCCCCCCCCHHHHHHHHHCCCCHHHHHH
MFERELQLGLLARPLDIDVHAGGYWLTSLKSKSLTPAMTLFRDWITAEASAAASAAADAD
HHHHHHHHHHCCCCCEEEEECCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AKLRPHLPLNALRAFESSARHLNFTRAGLELSVTQAAVSQQVRALEERLGCALFTRLPR
CCCCCCCCHHHHHHHHHHHHHCEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GLDLTDEGRALLPVLSDAFSRIETVLQQFDGGRLRQVLTLGVVGTFALGWLMPRLKRFRD
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
THPFVELRLRTHNNVVDLAAEGLDFAIRFGQGNWPATRNERLFDAPLTALCAPEIARRLT
CCCEEEEEEECCCCCHHHHHCCCEEEEEECCCCCCCCCCCEEECCCHHHHHHHHHHHHHC
QPADLAHETLLRSYRTDEWLGWFDAAQLEPWTVNGPVFDSSRLMVEAAMQGMGIALAPAC
CHHHHHHHHHHHHHCCCHHHCHHCCCCCCCEECCCCCCCCCHHHHHHHHHCCCCHHHHHH
MFERELQLGLLARPLDIDVHAGGYWLTSLKSKSLTPAMTLFRDWITAEASAAASAAADAD
HHHHHHHHHHCCCCCEEEEECCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8064842 [H]