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The map label for this gene is basR [H]

Identifier: 189353582

GI number: 189353582

Start: 1832290

End: 1832952

Strand: Direct

Name: basR [H]

Synonym: BMULJ_04826

Alternate gene names: 189353582

Gene position: 1832290-1832952 (Clockwise)

Preceding gene: 189353576

Following gene: 189353583

Centisome position: 74.09

GC content: 68.63

Gene sequence:

>663_bases
ATGCGCGTACTGCTCGTCGAGGACGATCCGCTGATCGGCAGCGGGCTCGAACAGGGGCTGAAACAGGAAGGCTTCGCGGT
CGACTGGGTGAAGGACGGCGACGCCGCGTCGCTCGCGCTGCGCTCGACCGGCTACGGGCTGCTGCTGCTCGATCTCGGGC
TGCCGAACCGCGACGGCCTCGCCGTGCTCGCATCGCTGCGCCGCCGCGACGAGACGCTGCCCGCGATCATCATCACCGCG
CGCGACGGCGTGCCGGACCGCATCGCCGGACTCGACAGCGGCGCCGACGACTATCTGGTCAAACCGTTCGCGCTCGAGGA
ACTGCTCGCACGCATCCGCGCCGTGAACCGCCGCCATGCCGGCCGCGCGCAGACGACGCTCGCGATCGGCCCGCTGCGCC
TCGATCCCGTCAAGCATCAGGTCTGGCTGCACGACGACGAAGTGCCGCTGTCGCCGAAGGAGTTCGTGCTGCTGCACGAG
CTGATGCGCGAGCCCGGCGCCGTGATTTCGCGCGAGCAGTTCGAGGAACGCCTGTACAGCTGGGGCGAGGAAATCGAGAG
CAACGCCGTGCAGGTGCACATCCACAACCTGCGCAAGAAACTCGGCCACGACATGATCCGCACGGTGCGCGGCGTCGGCT
ACCGGATCGGTGACGGCACATGA

Upstream 100 bases:

>100_bases
ATCGGCGGGGCTCGGATCGCGCGCATTAAGCTGCGCCTAAGATGCGCGCGCTTATCATGGAGGCCCGGGCGCACGGCGCC
CTCCAGGACCTACATCGAAC

Downstream 100 bases:

>100_bases
CGCGCCTGCAACGCGCGATCGCGCGCTGGCGCGGCGTGTCGCTGCGGCGGCGCCTGCTGATCTGGCTGCTGCCGGCCGCA
TGCGTGATCGGGCTCGCGGC

Product: OmpR family two-component system response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MRVLLVEDDPLIGSGLEQGLKQEGFAVDWVKDGDAASLALRSTGYGLLLLDLGLPNRDGLAVLASLRRRDETLPAIIITA
RDGVPDRIAGLDSGADDYLVKPFALEELLARIRAVNRRHAGRAQTTLAIGPLRLDPVKHQVWLHDDEVPLSPKEFVLLHE
LMREPGAVISREQFEERLYSWGEEIESNAVQVHIHNLRKKLGHDMIRTVRGVGYRIGDGT

Sequences:

>Translated_220_residues
MRVLLVEDDPLIGSGLEQGLKQEGFAVDWVKDGDAASLALRSTGYGLLLLDLGLPNRDGLAVLASLRRRDETLPAIIITA
RDGVPDRIAGLDSGADDYLVKPFALEELLARIRAVNRRHAGRAQTTLAIGPLRLDPVKHQVWLHDDEVPLSPKEFVLLHE
LMREPGAVISREQFEERLYSWGEEIESNAVQVHIHNLRKKLGHDMIRTVRGVGYRIGDGT
>Mature_220_residues
MRVLLVEDDPLIGSGLEQGLKQEGFAVDWVKDGDAASLALRSTGYGLLLLDLGLPNRDGLAVLASLRRRDETLPAIIITA
RDGVPDRIAGLDSGADDYLVKPFALEELLARIRAVNRRHAGRAQTTLAIGPLRLDPVKHQVWLHDDEVPLSPKEFVLLHE
LMREPGAVISREQFEERLYSWGEEIESNAVQVHIHNLRKKLGHDMIRTVRGVGYRIGDGT

Specific function: Member of the two-component regulatory system BasS/BasR. BasR induces the transcription of the ugd, ais, arnBCADTEF and eptA-basRS loci, all involved in resistance to polymyxin [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=218, Percent_Identity=50, Blast_Score=211, Evalue=2e-56,
Organism=Escherichia coli, GI1790552, Length=216, Percent_Identity=49.537037037037, Blast_Score=211, Evalue=2e-56,
Organism=Escherichia coli, GI87082012, Length=219, Percent_Identity=42.0091324200913, Blast_Score=153, Evalue=7e-39,
Organism=Escherichia coli, GI1786599, Length=223, Percent_Identity=39.9103139013453, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1787375, Length=218, Percent_Identity=34.8623853211009, Blast_Score=141, Evalue=3e-35,
Organism=Escherichia coli, GI1786784, Length=221, Percent_Identity=35.2941176470588, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1788394, Length=221, Percent_Identity=37.5565610859729, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI1789809, Length=236, Percent_Identity=34.7457627118644, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI2367329, Length=226, Percent_Identity=37.1681415929204, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1790860, Length=221, Percent_Identity=34.841628959276, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=34.2222222222222, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1787229, Length=220, Percent_Identity=31.8181818181818, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI145693140, Length=229, Percent_Identity=30.1310043668122, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1790863, Length=235, Percent_Identity=26.8085106382979, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790299, Length=115, Percent_Identity=35.6521739130435, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=29.9065420560748, Blast_Score=61, Evalue=7e-11,
Organism=Escherichia coli, GI1788521, Length=208, Percent_Identity=31.7307692307692, Blast_Score=60, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24429; Mature: 24429

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLLVEDDPLIGSGLEQGLKQEGFAVDWVKDGDAASLALRSTGYGLLLLDLGLPNRDGL
CEEEEECCCCCCCCHHHHHHHHCCCEEEEEECCCHHEEEEECCCCEEEEEEECCCCCCHH
AVLASLRRRDETLPAIIITARDGVPDRIAGLDSGADDYLVKPFALEELLARIRAVNRRHA
HHHHHHHHCCCCCCEEEEEECCCCCHHHHCCCCCCCCCEECHHHHHHHHHHHHHHHHHCC
GRAQTTLAIGPLRLDPVKHQVWLHDDEVPLSPKEFVLLHELMREPGAVISREQFEERLYS
CCCCEEEEECCEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
WGEEIESNAVQVHIHNLRKKLGHDMIRTVRGVGYRIGDGT
HHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHCCEECCCCC
>Mature Secondary Structure
MRVLLVEDDPLIGSGLEQGLKQEGFAVDWVKDGDAASLALRSTGYGLLLLDLGLPNRDGL
CEEEEECCCCCCCCHHHHHHHHCCCEEEEEECCCHHEEEEECCCCEEEEEEECCCCCCHH
AVLASLRRRDETLPAIIITARDGVPDRIAGLDSGADDYLVKPFALEELLARIRAVNRRHA
HHHHHHHHCCCCCCEEEEEECCCCCHHHHCCCCCCCCCEECHHHHHHHHHHHHHHHHHCC
GRAQTTLAIGPLRLDPVKHQVWLHDDEVPLSPKEFVLLHELMREPGAVISREQFEERLYS
CCCCEEEEECCEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
WGEEIESNAVQVHIHNLRKKLGHDMIRTVRGVGYRIGDGT
HHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHCCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8282725; 7610040; 9278503 [H]