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The map label for this gene is galE [H]

Identifier: 189353504

GI number: 189353504

Start: 1724599

End: 1725588

Strand: Direct

Name: galE [H]

Synonym: BMULJ_04748

Alternate gene names: 189353504

Gene position: 1724599-1725588 (Clockwise)

Preceding gene: 189353503

Following gene: 189353505

Centisome position: 69.73

GC content: 70.51

Gene sequence:

>990_bases
ATGAAAGTCTTCGTCACAGGCGGCGCCGGCTATATCGGCAGCCATACGTGCAAGGCGCTCGCGGAGGCCGGGCACGCGCC
GGTCGCGTACGACGATCTGTCGACCGGCCATCGCGACGCGGTGCGCTGGGGGCCGCTCGTCGTCGGCAGCATCCTCGACC
ACGACGCACTCGGCCGCGCGCTCGCCGCGCATCGGCCCGACATCGTGATTCACTTCGCGGCGCTCGCGTACGTCGGCGAG
TCGGTGCTCGCGCCCGACCGCTACTACGCGACGAACGTGACGGGCACCTGCACGCTGCTGAACGCGATGCGGGCGGCCGG
CGTCGGCCGGATCGTGCTGTCGTCGTCGTGCGCGACCTACGGGATTCCCGATGCGCTGCCGATCTGCGAACACACGCCGC
AGCATCCGATCAACCCGTATGGCTTCACGAAGTACGCGATGGAGCGGATGGCGGCCGACTTCGAGCGCGCCTACGGCATG
CAGTGGGTCGCGCTGCGCTACTTCAATGCAGCGGGCGCGGACCCGGACGGCCTGCTCGGCGAAAACCACGAACCCGAAAC
GCATGCGCTGCCGCTCGCGATCCGCGCGGCGCTCGGCACCGGCCGCCCGTTCACGGTGATGGGCACCGACTATCCGACGC
CGGACGGCTCCGCCGTGCGCGACTACGTGCACGTGAGCGATCTCGCCGATGCGCACGTCAAGGCCACCGCGTATCTGTGC
CGCGGCGGCCACAGCGTCGCGCTGAATCTCGGGACCGGCACGGGCACGTCGGTGCTCGAGCTCGTACGCGCAGTCGAAAC
GGTGACCGGCTCGCGCGTGCCGACCGTCATGGCCGCGCGCCGCCCCGGCGATCCGCCGGCGCTGTATGCGGACGCGACGA
AGGCCGCGCTCGTGCTCGGCTGGCGCCCGCGCTTCGCCGGGATCGAGCCGATGGTCGAGCATGCGGCGCGGTGGTTCCGT
CAGGACCTTCCGCTCGTGTCGAACAAGTAA

Upstream 100 bases:

>100_bases
GGCCGTGCATCGATCTCGACGAGGGGCTGCACCGCACCGTCGACTACTTCGCCCGGGAACTGTGGATCGCGCCGATGCTG
CAGATGACGGGAGCCGCCGC

Downstream 100 bases:

>100_bases
CACCGGGCGTCGTTCAACCAACCACGGGGATAACCATGAATGTGCGGATCGCCATCGTCGGCACGGGCTATGTCGGGCTC
GTCAGCGGCGCATGTCTGGC

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MKVFVTGGAGYIGSHTCKALAEAGHAPVAYDDLSTGHRDAVRWGPLVVGSILDHDALGRALAAHRPDIVIHFAALAYVGE
SVLAPDRYYATNVTGTCTLLNAMRAAGVGRIVLSSSCATYGIPDALPICEHTPQHPINPYGFTKYAMERMAADFERAYGM
QWVALRYFNAAGADPDGLLGENHEPETHALPLAIRAALGTGRPFTVMGTDYPTPDGSAVRDYVHVSDLADAHVKATAYLC
RGGHSVALNLGTGTGTSVLELVRAVETVTGSRVPTVMAARRPGDPPALYADATKAALVLGWRPRFAGIEPMVEHAARWFR
QDLPLVSNK

Sequences:

>Translated_329_residues
MKVFVTGGAGYIGSHTCKALAEAGHAPVAYDDLSTGHRDAVRWGPLVVGSILDHDALGRALAAHRPDIVIHFAALAYVGE
SVLAPDRYYATNVTGTCTLLNAMRAAGVGRIVLSSSCATYGIPDALPICEHTPQHPINPYGFTKYAMERMAADFERAYGM
QWVALRYFNAAGADPDGLLGENHEPETHALPLAIRAALGTGRPFTVMGTDYPTPDGSAVRDYVHVSDLADAHVKATAYLC
RGGHSVALNLGTGTGTSVLELVRAVETVTGSRVPTVMAARRPGDPPALYADATKAALVLGWRPRFAGIEPMVEHAARWFR
QDLPLVSNK
>Mature_329_residues
MKVFVTGGAGYIGSHTCKALAEAGHAPVAYDDLSTGHRDAVRWGPLVVGSILDHDALGRALAAHRPDIVIHFAALAYVGE
SVLAPDRYYATNVTGTCTLLNAMRAAGVGRIVLSSSCATYGIPDALPICEHTPQHPINPYGFTKYAMERMAADFERAYGM
QWVALRYFNAAGADPDGLLGENHEPETHALPLAIRAALGTGRPFTVMGTDYPTPDGSAVRDYVHVSDLADAHVKATAYLC
RGGHSVALNLGTGTGTSVLELVRAVETVTGSRVPTVMAARRPGDPPALYADATKAALVLGWRPRFAGIEPMVEHAARWFR
QDLPLVSNK

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=341, Percent_Identity=41.6422287390029, Blast_Score=227, Evalue=1e-59,
Organism=Homo sapiens, GI56118217, Length=341, Percent_Identity=41.6422287390029, Blast_Score=227, Evalue=1e-59,
Organism=Homo sapiens, GI189083684, Length=341, Percent_Identity=41.6422287390029, Blast_Score=227, Evalue=1e-59,
Organism=Homo sapiens, GI42516563, Length=333, Percent_Identity=27.6276276276276, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI7657641, Length=341, Percent_Identity=25.2199413489736, Blast_Score=87, Evalue=2e-17,
Organism=Escherichia coli, GI1786974, Length=315, Percent_Identity=42.2222222222222, Blast_Score=218, Evalue=4e-58,
Organism=Escherichia coli, GI1788353, Length=362, Percent_Identity=27.6243093922652, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI48994969, Length=349, Percent_Identity=27.7936962750716, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788365, Length=342, Percent_Identity=23.0994152046784, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI71982035, Length=341, Percent_Identity=36.950146627566, Blast_Score=198, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI71982038, Length=343, Percent_Identity=36.4431486880466, Blast_Score=197, Evalue=6e-51,
Organism=Caenorhabditis elegans, GI17568069, Length=323, Percent_Identity=26.9349845201238, Blast_Score=85, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17539532, Length=310, Percent_Identity=23.8709677419355, Blast_Score=76, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6319493, Length=337, Percent_Identity=37.3887240356083, Blast_Score=205, Evalue=7e-54,
Organism=Drosophila melanogaster, GI19923002, Length=348, Percent_Identity=39.9425287356322, Blast_Score=219, Evalue=2e-57,
Organism=Drosophila melanogaster, GI21356223, Length=330, Percent_Identity=24.2424242424242, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 34997; Mature: 34997

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVFVTGGAGYIGSHTCKALAEAGHAPVAYDDLSTGHRDAVRWGPLVVGSILDHDALGRA
CEEEEECCCCCCHHHHHHHHHHCCCCCEEECCCCCCCCCHHHHCCCHHHHHHCHHHHHHH
LAAHRPDIVIHFAALAYVGESVLAPDRYYATNVTGTCTLLNAMRAAGVGRIVLSSSCATY
HHHCCCCEEEHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHCCCCEEEEECCCCCC
GIPDALPICEHTPQHPINPYGFTKYAMERMAADFERAYGMQWVALRYFNAAGADPDGLLG
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEEHHCCCCCCCCCCC
ENHEPETHALPLAIRAALGTGRPFTVMGTDYPTPDGSAVRDYVHVSDLADAHVKATAYLC
CCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEE
RGGHSVALNLGTGTGTSVLELVRAVETVTGSRVPTVMAARRPGDPPALYADATKAALVLG
CCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCEEECCCCEEEEEE
WRPRFAGIEPMVEHAARWFRQDLPLVSNK
CCCCCCCCCHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKVFVTGGAGYIGSHTCKALAEAGHAPVAYDDLSTGHRDAVRWGPLVVGSILDHDALGRA
CEEEEECCCCCCHHHHHHHHHHCCCCCEEECCCCCCCCCHHHHCCCHHHHHHCHHHHHHH
LAAHRPDIVIHFAALAYVGESVLAPDRYYATNVTGTCTLLNAMRAAGVGRIVLSSSCATY
HHHCCCCEEEHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHCCCCEEEEECCCCCC
GIPDALPICEHTPQHPINPYGFTKYAMERMAADFERAYGMQWVALRYFNAAGADPDGLLG
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEEHHCCCCCCCCCCC
ENHEPETHALPLAIRAALGTGRPFTVMGTDYPTPDGSAVRDYVHVSDLADAHVKATAYLC
CCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEE
RGGHSVALNLGTGTGTSVLELVRAVETVTGSRVPTVMAARRPGDPPALYADATKAALVLG
CCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCEEECCCCEEEEEE
WRPRFAGIEPMVEHAARWFRQDLPLVSNK
CCCCCCCCCHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9236769 [H]