Click here to switch to the map view.

The map label for this gene is rfbB [C]

Identifier: 189353503

GI number: 189353503

Start: 1723595

End: 1724602

Strand: Direct

Name: rfbB [C]

Synonym: BMULJ_04747

Alternate gene names: 189353503

Gene position: 1723595-1724602 (Clockwise)

Preceding gene: 189353496

Following gene: 189353504

Centisome position: 69.69

GC content: 66.37

Gene sequence:

>1008_bases
ATGAATGACCGGGTAGCGATCGAGACGCGCGTCGGCCAGCGCGTGCTCGTGACGGGCGGCGCCGGATTTCTCGGCAGCTA
TGTATGCGAGCGCCTCGTCGTCGAGGGCGCGCACGTCGTCTGCGTCGACAGCCTGCTGACGGGACGCAAGCTGAACGTCG
CCGACCTGAAGGCGTCAGGTCGTTTCGAATTCGTGAAGGCCGACGTCACGCTCGGCCTGCCGCAGCTGCAGGTCGACGAG
ATCTGGAATCTCGCCTGCGCGGCATCGCCGCCGACGTATCAGCACGATCCGGTCCACACGATGATGACGAACGTGCTCGG
CATGAACCACTGTCTCGCGCTCGCCCGCAAGACCGGCGCGCGCGTGTTCCAGGCGTCGACGAGCGAGATCTACGGCGACC
CGAGCGTGCATCCGCAGATGGAAACGTATCGCGGCAACGTGAACACGATCGGCCCGCGCGCCTGCTACGACGAAGGCAAG
CGCGCCGCCGAGGCGCTCTGCTACGACTACTACCGCACCTACGGCGTCGACGTGCGCGTCGCGCGCATCTTCAATACGTA
TGGGCCGCGGATGTCGCCGCGCGACGGCCGCGTCGTGTCGAACTTCATCGTCGGCGCGCTGAACGGCGAGCCGCTCGAGA
TCTACGGCGACGGGTTGCAGACGCGCTCGTTCTGCTTCGTCAGCGATCTGATCGACGGCTTCTTCTGCCTGATGGGCGCC
GAGCGCAACGTCGGGATGCCGGTCAACATCGGCAATCCGGTCGAATTCACGATGATCGAGCTCGCGCAGAAGGTGCTCGC
GCTGACCGGCTCGCACTCCGAGATCGTATTCCGCCCGCTGCCGATCGACGATCCGCATCAGCGTCGCCCCGACATCTCGG
TCGCCGCGACCGAGCTCGGCTGGCGGCCGTGCATCGATCTCGACGAGGGGCTGCACCGCACCGTCGACTACTTCGCCCGG
GAACTGTGGATCGCGCCGATGCTGCAGATGACGGGAGCCGCCGCATGA

Upstream 100 bases:

>100_bases
ATGCCGGCACGACGTCCCTGCGGCGACGCGGGCAGCGTGCGCGCGTGCGCCGCAGCGCTCGCTGTCCGGCTCCCGGCGAT
GTGCGACGAAGGAGAAGACC

Downstream 100 bases:

>100_bases
AAGTCTTCGTCACAGGCGGCGCCGGCTATATCGGCAGCCATACGTGCAAGGCGCTCGCGGAGGCCGGGCACGCGCCGGTC
GCGTACGACGATCTGTCGAC

Product: dTDP-glucose 4,6-dehydratase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MNDRVAIETRVGQRVLVTGGAGFLGSYVCERLVVEGAHVVCVDSLLTGRKLNVADLKASGRFEFVKADVTLGLPQLQVDE
IWNLACAASPPTYQHDPVHTMMTNVLGMNHCLALARKTGARVFQASTSEIYGDPSVHPQMETYRGNVNTIGPRACYDEGK
RAAEALCYDYYRTYGVDVRVARIFNTYGPRMSPRDGRVVSNFIVGALNGEPLEIYGDGLQTRSFCFVSDLIDGFFCLMGA
ERNVGMPVNIGNPVEFTMIELAQKVLALTGSHSEIVFRPLPIDDPHQRRPDISVAATELGWRPCIDLDEGLHRTVDYFAR
ELWIAPMLQMTGAAA

Sequences:

>Translated_335_residues
MNDRVAIETRVGQRVLVTGGAGFLGSYVCERLVVEGAHVVCVDSLLTGRKLNVADLKASGRFEFVKADVTLGLPQLQVDE
IWNLACAASPPTYQHDPVHTMMTNVLGMNHCLALARKTGARVFQASTSEIYGDPSVHPQMETYRGNVNTIGPRACYDEGK
RAAEALCYDYYRTYGVDVRVARIFNTYGPRMSPRDGRVVSNFIVGALNGEPLEIYGDGLQTRSFCFVSDLIDGFFCLMGA
ERNVGMPVNIGNPVEFTMIELAQKVLALTGSHSEIVFRPLPIDDPHQRRPDISVAATELGWRPCIDLDEGLHRTVDYFAR
ELWIAPMLQMTGAAA
>Mature_335_residues
MNDRVAIETRVGQRVLVTGGAGFLGSYVCERLVVEGAHVVCVDSLLTGRKLNVADLKASGRFEFVKADVTLGLPQLQVDE
IWNLACAASPPTYQHDPVHTMMTNVLGMNHCLALARKTGARVFQASTSEIYGDPSVHPQMETYRGNVNTIGPRACYDEGK
RAAEALCYDYYRTYGVDVRVARIFNTYGPRMSPRDGRVVSNFIVGALNGEPLEIYGDGLQTRSFCFVSDLIDGFFCLMGA
ERNVGMPVNIGNPVEFTMIELAQKVLALTGSHSEIVFRPLPIDDPHQRRPDISVAATELGWRPCIDLDEGLHRTVDYFAR
ELWIAPMLQMTGAAA

Specific function: INVOLVED IN THE SYNTHESIS OF ENTEROBACTERIAL COMMON ANTIGEN (ECA) AND REQUIRED FOR SYNTHESIS OF LIPOPOLYSACCHARIDE O-SIDE CHAINS. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI42516563, Length=310, Percent_Identity=53.5483870967742, Blast_Score=350, Evalue=1e-96,
Organism=Homo sapiens, GI7657641, Length=325, Percent_Identity=26.4615384615385, Blast_Score=105, Evalue=8e-23,
Organism=Escherichia coli, GI48994969, Length=342, Percent_Identity=28.6549707602339, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1788353, Length=346, Percent_Identity=28.3236994219653, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1788589, Length=356, Percent_Identity=26.4044943820225, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786974, Length=339, Percent_Identity=24.7787610619469, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788365, Length=327, Percent_Identity=24.7706422018349, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17539532, Length=316, Percent_Identity=51.8987341772152, Blast_Score=323, Evalue=5e-89,
Organism=Caenorhabditis elegans, GI17568069, Length=330, Percent_Identity=27.8787878787879, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI115532424, Length=325, Percent_Identity=27.6923076923077, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21356223, Length=310, Percent_Identity=51.9354838709677, Blast_Score=324, Evalue=5e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36893; Mature: 36893

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDRVAIETRVGQRVLVTGGAGFLGSYVCERLVVEGAHVVCVDSLLTGRKLNVADLKASG
CCCCEEEEECCCCEEEEECCCHHHHHHHHHHHHHCCCCEEEEHHHHCCCCCCHHCCCCCC
RFEFVKADVTLGLPQLQVDEIWNLACAASPPTYQHDPVHTMMTNVLGMNHCLALARKTGA
CEEEEEEEEEECCCCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
RVFQASTSEIYGDPSVHPQMETYRGNVNTIGPRACYDEGKRAAEALCYDYYRTYGVDVRV
CEEECCCHHHCCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEE
ARIFNTYGPRMSPRDGRVVSNFIVGALNGEPLEIYGDGLQTRSFCFVSDLIDGFFCLMGA
EEHHHHCCCCCCCCCCCEEEHHEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCC
ERNVGMPVNIGNPVEFTMIELAQKVLALTGSHSEIVFRPLPIDDPHQRRPDISVAATELG
CCCCCCEEECCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCEEEEHHCC
WRPCIDLDEGLHRTVDYFARELWIAPMLQMTGAAA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNDRVAIETRVGQRVLVTGGAGFLGSYVCERLVVEGAHVVCVDSLLTGRKLNVADLKASG
CCCCEEEEECCCCEEEEECCCHHHHHHHHHHHHHCCCCEEEEHHHHCCCCCCHHCCCCCC
RFEFVKADVTLGLPQLQVDEIWNLACAASPPTYQHDPVHTMMTNVLGMNHCLALARKTGA
CEEEEEEEEEECCCCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
RVFQASTSEIYGDPSVHPQMETYRGNVNTIGPRACYDEGKRAAEALCYDYYRTYGVDVRV
CEEECCCHHHCCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEE
ARIFNTYGPRMSPRDGRVVSNFIVGALNGEPLEIYGDGLQTRSFCFVSDLIDGFFCLMGA
EEHHHHCCCCCCCCCCCEEEHHEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCC
ERNVGMPVNIGNPVEFTMIELAQKVLALTGSHSEIVFRPLPIDDPHQRRPDISVAATELG
CCCCCCEEECCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCEEEEHHCC
WRPCIDLDEGLHRTVDYFARELWIAPMLQMTGAAA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]