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The map label for this gene is ugd [H]

Identifier: 189353505

GI number: 189353505

Start: 1725630

End: 1727045

Strand: Direct

Name: ugd [H]

Synonym: BMULJ_04749

Alternate gene names: 189353505

Gene position: 1725630-1727045 (Clockwise)

Preceding gene: 189353504

Following gene: 189353506

Centisome position: 69.77

GC content: 67.8

Gene sequence:

>1416_bases
GTGCGGATCGCCATCGTCGGCACGGGCTATGTCGGGCTCGTCAGCGGCGCATGTCTGGCGGAGCTCGGACACGACGTCGT
CTGCATCGACAACAATCGCGGCAAGATCGACGCGCTGAATCAAGGCTGCATGCCGATCTACGAGCCGGGCCTCGACGCCT
TCGTCGCGCGCAACGTCGGACGCGGGACGCTGCGTTTCAGCAGCGATCTCGCCGCGAGCGTGCGCGACCGCGACGCGGTG
TTCATCGCGGTCGGCACGCCGACGCTGCCGGGCACCGATCGCGCGGACCTGCAATACGTCGAAGCGGCCGCGCGTGACAT
CGCATCGAACCTGAACGGCTTCACGGTCGTCGTCACGAAATCGACGGTACCGGTCGGCACGAACCGACGCGTGCAGGACA
TCGTCGAGCGCCATGCGCCGCCCGGCATCGACACCGCGATCGCGTCGAACCCCGAGTTCCTGCGCGAAGGATCGGCAATC
GACGACTTCATGCATCCGGACCGCGTCGTGTTCGGCGCCGAGCATCCGCGCGCGATCGAGATCATGAACGCGATCTATGC
ACCGCTCGCCGCGGCCGGCCATCTCGTGCTCGCGACCGAGATCGAGACGGCCGAACTCGTCAAGTACGCGGCCAATGCGT
TTCTCGCCGTGAAGATCAGCTACATCAACGAGATTTCGGACCTCTGCGAAGCGGTCGGGGCCGACGTCGAGCTCGTCGCG
AACGGAATGGGCCTCGACCGGCGGATCGGCGCGGCGTTCCTGAAGGCCGGGCCCGGCTGGGGCGGCTCGTGCTTTCCGAA
GGACACGCGCGCGCTGAAGGCGACCGCATCCGAACACGCTGTGCCGCTGCGCATCGTGAGCGCGGCGATCGAATCGAACG
CGCTGCGCAAGGCGCAGATCCTCCAGCGGATCGAAAACGCGTGCGGCGGCTCGATCAAGGGCAAGCGCATCGCGGTGCTC
GGCCTCACGTTCAAGGGGCAGACGGACGACGTGCGCGAAAGCCCGAGCATCGACGTGATCCAGCTGCTCGTCGGCGCCGG
CGCGCATATCCGCGCCTACGATCCCGCGCGGCCGCACGAGGCGTCGCGGCTGCTGCCGCAGGTGTTCATGGAAAGCTCGG
CGGTCGACGCGGTGCGCAGCGCCGACGCCGTCGTCGTGATGACCGAGTGGAAAGCCTTCGAGACGCTCGATCTCGCGGAT
CTCGCCGACCATATGGCGGACCCGGTGATGCTCGACATGCGCAACCTGTTCGACGAACGGCGCGCGGCCGACTGCGGCTT
TCGCCGCTACGAGCGCGTCGGCCGCTCGTGCACCGCGCGCACACCGGCCGATGCCGCGCGCGGTCGCGTGCCGGTCGCCG
ACGATACGACGGCTGCGTCGCAGCCTGCTTCAAAGCTGATGATCGACTCGAACTAA

Upstream 100 bases:

>100_bases
TGGTCGAGCATGCGGCGCGGTGGTTCCGTCAGGACCTTCCGCTCGTGTCGAACAAGTAACACCGGGCGTCGTTCAACCAA
CCACGGGGATAACCATGAAT

Downstream 100 bases:

>100_bases
CTCGCGTACGCGAGACCGTTGGGGGAACACCATGGAGAAGCTCGTTGCGTCGCTCGCCGGCGGCGCGGCGTCGGAGGCGT
CCGACGCCGAAGCCGGCCGC

Product: UDP-glucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 471; Mature: 471

Protein sequence:

>471_residues
MRIAIVGTGYVGLVSGACLAELGHDVVCIDNNRGKIDALNQGCMPIYEPGLDAFVARNVGRGTLRFSSDLAASVRDRDAV
FIAVGTPTLPGTDRADLQYVEAAARDIASNLNGFTVVVTKSTVPVGTNRRVQDIVERHAPPGIDTAIASNPEFLREGSAI
DDFMHPDRVVFGAEHPRAIEIMNAIYAPLAAAGHLVLATEIETAELVKYAANAFLAVKISYINEISDLCEAVGADVELVA
NGMGLDRRIGAAFLKAGPGWGGSCFPKDTRALKATASEHAVPLRIVSAAIESNALRKAQILQRIENACGGSIKGKRIAVL
GLTFKGQTDDVRESPSIDVIQLLVGAGAHIRAYDPARPHEASRLLPQVFMESSAVDAVRSADAVVVMTEWKAFETLDLAD
LADHMADPVMLDMRNLFDERRAADCGFRRYERVGRSCTARTPADAARGRVPVADDTTAASQPASKLMIDSN

Sequences:

>Translated_471_residues
MRIAIVGTGYVGLVSGACLAELGHDVVCIDNNRGKIDALNQGCMPIYEPGLDAFVARNVGRGTLRFSSDLAASVRDRDAV
FIAVGTPTLPGTDRADLQYVEAAARDIASNLNGFTVVVTKSTVPVGTNRRVQDIVERHAPPGIDTAIASNPEFLREGSAI
DDFMHPDRVVFGAEHPRAIEIMNAIYAPLAAAGHLVLATEIETAELVKYAANAFLAVKISYINEISDLCEAVGADVELVA
NGMGLDRRIGAAFLKAGPGWGGSCFPKDTRALKATASEHAVPLRIVSAAIESNALRKAQILQRIENACGGSIKGKRIAVL
GLTFKGQTDDVRESPSIDVIQLLVGAGAHIRAYDPARPHEASRLLPQVFMESSAVDAVRSADAVVVMTEWKAFETLDLAD
LADHMADPVMLDMRNLFDERRAADCGFRRYERVGRSCTARTPADAARGRVPVADDTTAASQPASKLMIDSN
>Mature_471_residues
MRIAIVGTGYVGLVSGACLAELGHDVVCIDNNRGKIDALNQGCMPIYEPGLDAFVARNVGRGTLRFSSDLAASVRDRDAV
FIAVGTPTLPGTDRADLQYVEAAARDIASNLNGFTVVVTKSTVPVGTNRRVQDIVERHAPPGIDTAIASNPEFLREGSAI
DDFMHPDRVVFGAEHPRAIEIMNAIYAPLAAAGHLVLATEIETAELVKYAANAFLAVKISYINEISDLCEAVGADVELVA
NGMGLDRRIGAAFLKAGPGWGGSCFPKDTRALKATASEHAVPLRIVSAAIESNALRKAQILQRIENACGGSIKGKRIAVL
GLTFKGQTDDVRESPSIDVIQLLVGAGAHIRAYDPARPHEASRLLPQVFMESSAVDAVRSADAVVVMTEWKAFETLDLAD
LADHMADPVMLDMRNLFDERRAADCGFRRYERVGRSCTARTPADAARGRVPVADDTTAASQPASKLMIDSN

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=486, Percent_Identity=37.4485596707819, Blast_Score=284, Evalue=1e-76,
Organism=Homo sapiens, GI296040438, Length=387, Percent_Identity=37.984496124031, Blast_Score=234, Evalue=1e-61,
Organism=Homo sapiens, GI296040443, Length=336, Percent_Identity=37.5, Blast_Score=193, Evalue=3e-49,
Organism=Escherichia coli, GI1788340, Length=410, Percent_Identity=30.9756097560976, Blast_Score=165, Evalue=6e-42,
Organism=Escherichia coli, GI48994968, Length=412, Percent_Identity=28.1553398058252, Blast_Score=139, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI17560350, Length=460, Percent_Identity=35.4347826086957, Blast_Score=242, Evalue=3e-64,
Organism=Drosophila melanogaster, GI17136908, Length=469, Percent_Identity=37.953091684435, Blast_Score=275, Evalue=5e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 50230; Mature: 50230

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIAIVGTGYVGLVSGACLAELGHDVVCIDNNRGKIDALNQGCMPIYEPGLDAFVARNVG
CEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCCCEEECCCCCCCCCCCCHHHHHHHCCC
RGTLRFSSDLAASVRDRDAVFIAVGTPTLPGTDRADLQYVEAAARDIASNLNGFTVVVTK
CCEEEECCHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEE
STVPVGTNRRVQDIVERHAPPGIDTAIASNPEFLREGSAIDDFMHPDRVVFGAEHPRAIE
CCCCCCCCCHHHHHHHHCCCCCCCHHHCCCHHHHHCCCCHHHHCCCCEEEECCCCCHHHH
IMNAIYAPLAAAGHLVLATEIETAELVKYAANAFLAVKISYINEISDLCEAVGADVELVA
HHHHHHHHHHHCCCEEEEECCCHHHHHHHHHCEEEEEEEHHHHHHHHHHHHHCCCEEEEE
NGMGLDRRIGAAFLKAGPGWGGSCFPKDTRALKATASEHAVPLRIVSAAIESNALRKAQI
CCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
LQRIENACGGSIKGKRIAVLGLTFKGQTDDVRESPSIDVIQLLVGAGAHIRAYDPARPHE
HHHHHHHCCCCCCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHCCCCEEEECCCCCCCH
ASRLLPQVFMESSAVDAVRSADAVVVMTEWKAFETLDLADLADHMADPVMLDMRNLFDER
HHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHH
RAADCGFRRYERVGRSCTARTPADAARGRVPVADDTTAASQPASKLMIDSN
HHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCEECCC
>Mature Secondary Structure
MRIAIVGTGYVGLVSGACLAELGHDVVCIDNNRGKIDALNQGCMPIYEPGLDAFVARNVG
CEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCCCEEECCCCCCCCCCCCHHHHHHHCCC
RGTLRFSSDLAASVRDRDAVFIAVGTPTLPGTDRADLQYVEAAARDIASNLNGFTVVVTK
CCEEEECCHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEE
STVPVGTNRRVQDIVERHAPPGIDTAIASNPEFLREGSAIDDFMHPDRVVFGAEHPRAIE
CCCCCCCCCHHHHHHHHCCCCCCCHHHCCCHHHHHCCCCHHHHCCCCEEEECCCCCHHHH
IMNAIYAPLAAAGHLVLATEIETAELVKYAANAFLAVKISYINEISDLCEAVGADVELVA
HHHHHHHHHHHCCCEEEEECCCHHHHHHHHHCEEEEEEEHHHHHHHHHHHHHCCCEEEEE
NGMGLDRRIGAAFLKAGPGWGGSCFPKDTRALKATASEHAVPLRIVSAAIESNALRKAQI
CCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
LQRIENACGGSIKGKRIAVLGLTFKGQTDDVRESPSIDVIQLLVGAGAHIRAYDPARPHE
HHHHHHHCCCCCCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHCCCCEEEECCCCCCCH
ASRLLPQVFMESSAVDAVRSADAVVVMTEWKAFETLDLADLADHMADPVMLDMRNLFDER
HHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHH
RAADCGFRRYERVGRSCTARTPADAARGRVPVADDTTAASQPASKLMIDSN
HHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9765575; 11481430 [H]