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The map label for this gene is mocR [H]

Identifier: 189352948

GI number: 189352948

Start: 1102986

End: 1104473

Strand: Reverse

Name: mocR [H]

Synonym: BMULJ_04182

Alternate gene names: 189352948

Gene position: 1104473-1102986 (Counterclockwise)

Preceding gene: 189352953

Following gene: 189352947

Centisome position: 44.66

GC content: 71.3

Gene sequence:

>1488_bases
ATGGACATCGCCATCCGCATCGAAGGCCGACACGACCTGACCGGCCAAATCTACCGCCAGCTGCGCACCGCGATCGTCGA
CGGGCGGCTCGAAGGCGGCGCACGGCTGCCGTCGACGCGCGATCTCGCGAAGCAGCTCGGCGTGTCGCGCAAGACGACGC
TCGATGCGTTCGAACGGCTCGTCGCCGAAGGCTATCTGCACACGCGTGCAGGCGACGGCACGTTCGTCGCCGACGGGCTC
GCGCGCGTCCCGCATGCGGCCGACGCGCCGGGGCCGTCGCTCGTGCACGACACGCCGCGCGCCGACGCGGTCGATGCGCG
CGCATGGTGGAACGACCTGCCCGACGCGCTGCCGATGCCGATGCCGGCCGACACGCCGCGCGACGACTTCCGCGGCGGCG
TCACCGACAAGACGCTGTTCCCGTTCGACACGTGGCGGCGCTGTCTGCATCACGCGCTGCGCCAGCAGGCGCGCGTGCGC
GGCCAATATCACGAGCCGGCCGGCGATGCGCAGCTGCGCGGCGCGATCGCGCGCTACGTCGGCTTCCGCCGCGCGGTGGT
CTGCAACTGGGACGACGTGATCGTCACGCAGGGCGCGCAGCAGGCGCTCGATCTGCTCGCCCGCGTCGTCGTGCGGCCCG
GCGACGTCGTCGCGGTCGAAGATCCCGGCTACCCGCCGGCCCGCGCCGCGTTCTCGTCGGTCGGTGCAACGGTGATCGGC
GTGCCGGTCGACGCGCACGGGCTCGTGACCGAGCGGCTGCCCGACGAGGCGCGGCTCGTCTACGTCACACCCTCGCACCA
GTTTCCGCTCGGGATGCCGATGTCGCTCGAGCGGCGCATCGCGCTGCTCGAATGGGCGCAGCGTCGGCGCGCGGTGATCA
TCGAGGACGACTACGACGGCGAATTCCGCTTCGAGGGGCGGCCCGTCGAATCGCTGAAGAGCCTCGATCGCACGGGGCTC
GTCGCCTACGTCGGCACGTTCTCGAAGACGATCTTCCCGGAACTGCGGATCGGCTATGCGATTCCGCCGCGCGCGCTGCG
CGGCGCGCTCTGCAAAGCGAAGCAGATCGTCGACTGGCATACGTGCACGCTGACGCAGGCGGCGCTTGCGCGCTTCATGC
TCGATGGCGATTTCGCGCGGCATCTGCGCCGCGTGCAGAAGCACTACGATGCGCGCCGCAAGATGGTGATCGCGCATCTG
CGCGGCGCGCTCGCGCCGTGGTTCGACGCGATCGTGCCGAGCGCCGGCATCCACCTCGCCGCGCTGCTGAAGCCGGGCGT
CGACGAAGCGGCGCTGATCGGCGCGGCGCGCGCGCACGACATCGGGCTCTACGGCATCTCGATGTTTCACGTCGACGTGC
CGGTACGCGCGGGGCTGCTGTTCGGGTATGGCGGCATCGATGCGGTACGCATCGACGCGACGCTCGCGCGGCTCGCCGCG
CTGCTCGGCGACGGCGTCGCCGATGAGCGCGCGCCACTGGTCACCTGA

Upstream 100 bases:

>100_bases
GCCGCGCGCGGCGGCGCTCGCGTTCGGCGTTCCGGCCGGTGCATACTCGCGGTATGCCAATCGGCCAAAAAACGACCCAA
TCGAGGTAACCACTACTGCG

Downstream 100 bases:

>100_bases
TATTTCCCGAAATTGGCCATTCAAGCAGGCCAGTACGGCTCGTAAAGTGGGTCCATCGCGCCACCGTGCGCTCCAACCGA
AAGAGGACCTGCGATGCAAC

Product: DNA-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 495; Mature: 495

Protein sequence:

>495_residues
MDIAIRIEGRHDLTGQIYRQLRTAIVDGRLEGGARLPSTRDLAKQLGVSRKTTLDAFERLVAEGYLHTRAGDGTFVADGL
ARVPHAADAPGPSLVHDTPRADAVDARAWWNDLPDALPMPMPADTPRDDFRGGVTDKTLFPFDTWRRCLHHALRQQARVR
GQYHEPAGDAQLRGAIARYVGFRRAVVCNWDDVIVTQGAQQALDLLARVVVRPGDVVAVEDPGYPPARAAFSSVGATVIG
VPVDAHGLVTERLPDEARLVYVTPSHQFPLGMPMSLERRIALLEWAQRRRAVIIEDDYDGEFRFEGRPVESLKSLDRTGL
VAYVGTFSKTIFPELRIGYAIPPRALRGALCKAKQIVDWHTCTLTQAALARFMLDGDFARHLRRVQKHYDARRKMVIAHL
RGALAPWFDAIVPSAGIHLAALLKPGVDEAALIGAARAHDIGLYGISMFHVDVPVRAGLLFGYGGIDAVRIDATLARLAA
LLGDGVADERAPLVT

Sequences:

>Translated_495_residues
MDIAIRIEGRHDLTGQIYRQLRTAIVDGRLEGGARLPSTRDLAKQLGVSRKTTLDAFERLVAEGYLHTRAGDGTFVADGL
ARVPHAADAPGPSLVHDTPRADAVDARAWWNDLPDALPMPMPADTPRDDFRGGVTDKTLFPFDTWRRCLHHALRQQARVR
GQYHEPAGDAQLRGAIARYVGFRRAVVCNWDDVIVTQGAQQALDLLARVVVRPGDVVAVEDPGYPPARAAFSSVGATVIG
VPVDAHGLVTERLPDEARLVYVTPSHQFPLGMPMSLERRIALLEWAQRRRAVIIEDDYDGEFRFEGRPVESLKSLDRTGL
VAYVGTFSKTIFPELRIGYAIPPRALRGALCKAKQIVDWHTCTLTQAALARFMLDGDFARHLRRVQKHYDARRKMVIAHL
RGALAPWFDAIVPSAGIHLAALLKPGVDEAALIGAARAHDIGLYGISMFHVDVPVRAGLLFGYGGIDAVRIDATLARLAA
LLGDGVADERAPLVT
>Mature_495_residues
MDIAIRIEGRHDLTGQIYRQLRTAIVDGRLEGGARLPSTRDLAKQLGVSRKTTLDAFERLVAEGYLHTRAGDGTFVADGL
ARVPHAADAPGPSLVHDTPRADAVDARAWWNDLPDALPMPMPADTPRDDFRGGVTDKTLFPFDTWRRCLHHALRQQARVR
GQYHEPAGDAQLRGAIARYVGFRRAVVCNWDDVIVTQGAQQALDLLARVVVRPGDVVAVEDPGYPPARAAFSSVGATVIG
VPVDAHGLVTERLPDEARLVYVTPSHQFPLGMPMSLERRIALLEWAQRRRAVIIEDDYDGEFRFEGRPVESLKSLDRTGL
VAYVGTFSKTIFPELRIGYAIPPRALRGALCKAKQIVDWHTCTLTQAALARFMLDGDFARHLRRVQKHYDARRKMVIAHL
RGALAPWFDAIVPSAGIHLAALLKPGVDEAALIGAARAHDIGLYGISMFHVDVPVRAGLLFGYGGIDAVRIDATLARLAA
LLGDGVADERAPLVT

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=392, Percent_Identity=23.7244897959184, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI33469970, Length=392, Percent_Identity=23.7244897959184, Blast_Score=100, Evalue=5e-21,
Organism=Escherichia coli, GI1790797, Length=471, Percent_Identity=29.0870488322718, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1787710, Length=442, Percent_Identity=26.6968325791855, Blast_Score=128, Evalue=7e-31,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 54230; Mature: 54230

Theoretical pI: Translated: 8.59; Mature: 8.59

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIAIRIEGRHDLTGQIYRQLRTAIVDGRLEGGARLPSTRDLAKQLGVSRKTTLDAFERL
CCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHH
VAEGYLHTRAGDGTFVADGLARVPHAADAPGPSLVHDTPRADAVDARAWWNDLPDALPMP
HHHCCCEECCCCCCEEHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCC
MPADTPRDDFRGGVTDKTLFPFDTWRRCLHHALRQQARVRGQYHEPAGDAQLRGAIARYV
CCCCCCHHHHCCCCCCCEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
GFRRAVVCNWDDVIVTQGAQQALDLLARVVVRPGDVVAVEDPGYPPARAAFSSVGATVIG
HHHEEEEECCCCEEEECCHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHCCCEEEE
VPVDAHGLVTERLPDEARLVYVTPSHQFPLGMPMSLERRIALLEWAQRRRAVIIEDDYDG
CCCCCCCCHHHCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCC
EFRFEGRPVESLKSLDRTGLVAYVGTFSKTIFPELRIGYAIPPRALRGALCKAKQIVDWH
EEEECCCCHHHHHCCCCCCHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHCHH
TCTLTQAALARFMLDGDFARHLRRVQKHYDARRKMVIAHLRGALAPWFDAIVPSAGIHLA
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEH
ALLKPGVDEAALIGAARAHDIGLYGISMFHVDVPVRAGLLFGYGGIDAVRIDATLARLAA
HHHCCCCCHHHHHHHHHHCCCEEEEEEEEEEECCHHHCEEEECCCCCEEEHHHHHHHHHH
LLGDGVADERAPLVT
HHCCCCCCCCCCCCC
>Mature Secondary Structure
MDIAIRIEGRHDLTGQIYRQLRTAIVDGRLEGGARLPSTRDLAKQLGVSRKTTLDAFERL
CCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHH
VAEGYLHTRAGDGTFVADGLARVPHAADAPGPSLVHDTPRADAVDARAWWNDLPDALPMP
HHHCCCEECCCCCCEEHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCC
MPADTPRDDFRGGVTDKTLFPFDTWRRCLHHALRQQARVRGQYHEPAGDAQLRGAIARYV
CCCCCCHHHHCCCCCCCEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
GFRRAVVCNWDDVIVTQGAQQALDLLARVVVRPGDVVAVEDPGYPPARAAFSSVGATVIG
HHHEEEEECCCCEEEECCHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHCCCEEEE
VPVDAHGLVTERLPDEARLVYVTPSHQFPLGMPMSLERRIALLEWAQRRRAVIIEDDYDG
CCCCCCCCHHHCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCC
EFRFEGRPVESLKSLDRTGLVAYVGTFSKTIFPELRIGYAIPPRALRGALCKAKQIVDWH
EEEECCCCHHHHHCCCCCCHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHCHH
TCTLTQAALARFMLDGDFARHLRRVQKHYDARRKMVIAHLRGALAPWFDAIVPSAGIHLA
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEH
ALLKPGVDEAALIGAARAHDIGLYGISMFHVDVPVRAGLLFGYGGIDAVRIDATLARLAA
HHHCCCCCHHHHHHHHHHCCCEEEEEEEEEEECCHHHCEEEECCCCCEEEHHHHHHHHHH
LLGDGVADERAPLVT
HHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]