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The map label for this gene is yogA [H]

Identifier: 189352162

GI number: 189352162

Start: 190687

End: 191706

Strand: Reverse

Name: yogA [H]

Synonym: BMULJ_03380

Alternate gene names: 189352162

Gene position: 191706-190687 (Counterclockwise)

Preceding gene: 189352166

Following gene: 189352158

Centisome position: 7.75

GC content: 69.02

Gene sequence:

>1020_bases
ATGCAAGCATGGCAACAGACACCGGGCGACGGCCTCGCCGGGCTTCGCCGCATCGATGCGACGCACCGGCCGGTCGGACC
GACCGACGTCGTCGTGAAGATCCACTCGGTATCGCTGAACTATCGCGACCTGATGTTCGCGCGCGGCGACTACGTCGGCA
TCGGCGACGCACCGTTGATTCCGGTCGCGGACGGCGCCGGCGAAGTGGTCGAAATCGGCCGCGACGTCACGCGCTTCAAG
CCCGGCGATCGCGTGATCAACACGTATTTCCCGCGCTGGATCGACGGGCCGCCCACGCCGTCGAAAGTCGCCGGCTCGCC
CGGCGCGCAGTTCGACGGCGTGCTTGCCGAGCGCTTCGTCACGGACGAAGCCGCACTGGTCGCGATCCCCGCGCATCTCG
ATTACGACGAGGCATCGACGCTGTCGTGCGCCGGCATCACCGCATGGAATGCGCTGTTCGCCGACGGCGGCCTCGCGCCC
GGTTCGACCGTCGTGCTGCTCGGCACCGGCGGCGTATCGATCGTCGCGCTGCAACTCGCGCACGCGGCGGGGCTGCGCAC
GATCATCACGTCGTCGAGCGACGCGAAGCTCGAGCGCGCCCGCGCGCTCGGCGCCGACGAGACGATCAACTATCGCGCGA
CACCCGACTGGCAGCACGAAGTGCTGCGGCTCACCGACGGCGCGGGCGCCGATCTGGTCGTCGAAGTCGGCGGCAAGGAT
ACCTTGCCGCGCTCGGTCGCGGCGACCAAGCTGGGCGGCGTCGTGTCGGTGATCGGCGGCGTCAGCGGCTTCGGCGGGCC
CGAGCTCGGACTGCTGTCGCTGATCGGCGGCATCCGCCGGCTGCACGGCATCATGGTGGGCAGCCGCTCGATGCTCGACG
AGGTCGTGCAGTTGTTCGACAGAAAGCAGCTCCGCCCGATCGTCGATCGCGTGTTCGCCTTCGACGAGGCGCCGGCCGCC
TATGCGCATCTGCAGTCGGGACAGCACTTCGGCAAGATCGTGATCCGCGTCGCGCACTAA

Upstream 100 bases:

>100_bases
TTTGTTTCCACATTGGCGACAGTCAGTGTCCCGATTCTCGTCAATGCGTCCCGTCAAGCAACACTATGATAGTCCGCACA
GTCACGAACAAGGAGTCGAC

Downstream 100 bases:

>100_bases
CGCGATAAACGGAACGGGGCGGACGACTCGCGCCGCCCGCCCCGTGCTCGACTGCCGCGTGCGCTCGTCAGAACTTGTGT
CGAATTCCGGCGTGCACCAT

Product: Zn-dependent NADPH:quinone reductase

Products: aldehyde; ketone; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MQAWQQTPGDGLAGLRRIDATHRPVGPTDVVVKIHSVSLNYRDLMFARGDYVGIGDAPLIPVADGAGEVVEIGRDVTRFK
PGDRVINTYFPRWIDGPPTPSKVAGSPGAQFDGVLAERFVTDEAALVAIPAHLDYDEASTLSCAGITAWNALFADGGLAP
GSTVVLLGTGGVSIVALQLAHAAGLRTIITSSSDAKLERARALGADETINYRATPDWQHEVLRLTDGAGADLVVEVGGKD
TLPRSVAATKLGGVVSVIGGVSGFGGPELGLLSLIGGIRRLHGIMVGSRSMLDEVVQLFDRKQLRPIVDRVFAFDEAPAA
YAHLQSGQHFGKIVIRVAH

Sequences:

>Translated_339_residues
MQAWQQTPGDGLAGLRRIDATHRPVGPTDVVVKIHSVSLNYRDLMFARGDYVGIGDAPLIPVADGAGEVVEIGRDVTRFK
PGDRVINTYFPRWIDGPPTPSKVAGSPGAQFDGVLAERFVTDEAALVAIPAHLDYDEASTLSCAGITAWNALFADGGLAP
GSTVVLLGTGGVSIVALQLAHAAGLRTIITSSSDAKLERARALGADETINYRATPDWQHEVLRLTDGAGADLVVEVGGKD
TLPRSVAATKLGGVVSVIGGVSGFGGPELGLLSLIGGIRRLHGIMVGSRSMLDEVVQLFDRKQLRPIVDRVFAFDEAPAA
YAHLQSGQHFGKIVIRVAH
>Mature_339_residues
MQAWQQTPGDGLAGLRRIDATHRPVGPTDVVVKIHSVSLNYRDLMFARGDYVGIGDAPLIPVADGAGEVVEIGRDVTRFK
PGDRVINTYFPRWIDGPPTPSKVAGSPGAQFDGVLAERFVTDEAALVAIPAHLDYDEASTLSCAGITAWNALFADGGLAP
GSTVVLLGTGGVSIVALQLAHAAGLRTIITSSSDAKLERARALGADETINYRATPDWQHEVLRLTDGAGADLVVEVGGKD
TLPRSVAATKLGGVVSVIGGVSGFGGPELGLLSLIGGIRRLHGIMVGSRSMLDEVVQLFDRKQLRPIVDRVFAFDEAPAA
YAHLQSGQHFGKIVIRVAH

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI47519420, Length=346, Percent_Identity=28.0346820809249, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI18379349, Length=332, Percent_Identity=25, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI22538446, Length=329, Percent_Identity=26.4437689969605, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI22538444, Length=329, Percent_Identity=26.4437689969605, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI71565152, Length=347, Percent_Identity=26.2247838616715, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI194239674, Length=236, Percent_Identity=25, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI13236495, Length=236, Percent_Identity=25, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI156627571, Length=322, Percent_Identity=23.9130434782609, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1789651, Length=287, Percent_Identity=28.9198606271777, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI87082125, Length=350, Percent_Identity=26.5714285714286, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786518, Length=305, Percent_Identity=26.5573770491803, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1788073, Length=273, Percent_Identity=27.1062271062271, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI87081918, Length=338, Percent_Identity=27.810650887574, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17562584, Length=318, Percent_Identity=25.4716981132075, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17562582, Length=317, Percent_Identity=24.2902208201893, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17565904, Length=361, Percent_Identity=26.8698060941828, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17562876, Length=247, Percent_Identity=25.5060728744939, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71997431, Length=345, Percent_Identity=26.6666666666667, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25146526, Length=312, Percent_Identity=26.2820512820513, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319520, Length=344, Percent_Identity=26.1627906976744, Blast_Score=83, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6322619, Length=343, Percent_Identity=26.2390670553936, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6319955, Length=343, Percent_Identity=26.2390670553936, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6319621, Length=339, Percent_Identity=23.598820058997, Blast_Score=76, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6324486, Length=322, Percent_Identity=25.1552795031056, Blast_Score=74, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6323961, Length=322, Percent_Identity=24.223602484472, Blast_Score=73, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6323729, Length=322, Percent_Identity=22.6708074534161, Blast_Score=70, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24581345, Length=353, Percent_Identity=26.0623229461756, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI221330659, Length=237, Percent_Identity=29.957805907173, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI19920632, Length=237, Percent_Identity=29.957805907173, Blast_Score=78, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: 1.1.1.1

Molecular weight: Translated: 35663; Mature: 35663

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAWQQTPGDGLAGLRRIDATHRPVGPTDVVVKIHSVSLNYRDLMFARGDYVGIGDAPLI
CCCCCCCCCCHHHHHHHHCCCCCCCCCCEEEEEEEEEECCHHHHEEECCCEEECCCCCCE
PVADGAGEVVEIGRDVTRFKPGDRVINTYFPRWIDGPPTPSKVAGSPGAQFDGVLAERFV
EECCCCCHHHHHCCHHHHCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
TDEAALVAIPAHLDYDEASTLSCAGITAWNALFADGGLAPGSTVVLLGTGGVSIVALQLA
CCCCEEEEEECCCCCCCCCCEEECCHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHH
HAAGLRTIITSSSDAKLERARALGADETINYRATPDWQHEVLRLTDGAGADLVVEVGGKD
HHCCCEEEEECCCCHHHHHHHHCCCCCCEEECCCCCHHHHHEEEECCCCCEEEEEECCCC
TLPRSVAATKLGGVVSVIGGVSGFGGPELGLLSLIGGIRRLHGIMVGSRSMLDEVVQLFD
CCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
RKQLRPIVDRVFAFDEAPAAYAHLQSGQHFGKIVIRVAH
HHHHHHHHHHHHHCCCCCHHHHHHHCCCCEEEEEEEECC
>Mature Secondary Structure
MQAWQQTPGDGLAGLRRIDATHRPVGPTDVVVKIHSVSLNYRDLMFARGDYVGIGDAPLI
CCCCCCCCCCHHHHHHHHCCCCCCCCCCEEEEEEEEEECCHHHHEEECCCEEECCCCCCE
PVADGAGEVVEIGRDVTRFKPGDRVINTYFPRWIDGPPTPSKVAGSPGAQFDGVLAERFV
EECCCCCHHHHHCCHHHHCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
TDEAALVAIPAHLDYDEASTLSCAGITAWNALFADGGLAPGSTVVLLGTGGVSIVALQLA
CCCCEEEEEECCCCCCCCCCEEECCHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHH
HAAGLRTIITSSSDAKLERARALGADETINYRATPDWQHEVLRLTDGAGADLVVEVGGKD
HHCCCEEEEECCCCHHHHHHHHCCCCCCEEECCCCCHHHHHEEEECCCCCEEEEEECCCC
TLPRSVAATKLGGVVSVIGGVSGFGGPELGLLSLIGGIRRLHGIMVGSRSMLDEVVQLFD
CCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
RKQLRPIVDRVFAFDEAPAAYAHLQSGQHFGKIVIRVAH
HHHHHHHHHHHHHCCCCCHHHHHHHCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: alcohol; NAD+

Specific reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]