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The map label for this gene is abgR [H]

Identifier: 189352158

GI number: 189352158

Start: 186190

End: 187143

Strand: Reverse

Name: abgR [H]

Synonym: BMULJ_03376

Alternate gene names: 189352158

Gene position: 187143-186190 (Counterclockwise)

Preceding gene: 189352162

Following gene: 189352157

Centisome position: 7.57

GC content: 69.29

Gene sequence:

>954_bases
ATGAAACTGCATCAGTTGCAGGCGCTCGTCGCGAGCGCCGAAGCCGGCAGCATTCGCGGCGCGGCGCGCACGCTCGGCTT
GTCGCAGGCCGCGGTCACGCGCGCGCTGCGCGAGCTGGAGGCCGCCGAGCGGCTGCCGCTGCTCGTGCGCGCGCCGGAAG
GGATCGGCTTCACCGAATACGGCAAGGCGCTGCTCACGCACGCGAAACTCGTGCTGAAACAGCTCGAGCAGGCGCACGAC
GATCTCGCGCGGATGCGCGGCCGCGTCGACGGGCGGCTGAGCATCGGCGTGACGCCGTGGCTCACGCTGACGTTTCTCGC
GGAGACGGTGCTGCGCTTTCGCGAACGGATGCCGGACGTGCGTCTCGAACTCTACGAAGCGCTGATGGCCGTCGCACAGC
CGCTGCTGCGCGACGGCAGCATGGATTTCGCGCTCGGCCACATCCATCCCGGCAGCGGCGCGCAGGAATTCGCGTTCGAG
CCGATGCTGCGCTACGACACGGCGGTGATGGTGCGCGCGGGGCACCCGCGCGAACGCGCGCGCTCGATCCACGATCTGCT
CGACGACGACTGGGTGCTCAATTCGACCGCCGACGGTCAGACGGCGCTCGTCGACTATCTGTTCACGCGGCACGGCGCGC
GCATTGACGAGCGGCGCATCGTGCGCGCGCAGTCGGTGTCGATGCTGCAGACGATGCTCGAGCAGGCCGACATGTGCACG
TGGTGCCCGACGATCCTCGCCGCGGTGCCGTCGTTCGGCGAACGGATGCGCGCGCTGTCGTTGAAGGAGACCTTCGAGCC
GCGCGAGCTCGGCGTCGTCACGCGCCGCAGCAGTACGCTCAGCGAGGCCGCGCGCTGCTTCATCGACTGCCTGCTGCACG
TGATCCGGCGGCATGCGCGCTCGGCGCGCAAGGAAGACCTCGCGCTGTTCAAGACCGTGTCGCTGCTGATCTGA

Upstream 100 bases:

>100_bases
GGCAGATCGTGGCGCGATCGTATGCAGCGAAAATCCCGGCGAACAGCCGCGGTTTCGTTATGATGACAACGTTTCGTTGT
CGGGTATCGGGTCTCGAACC

Downstream 100 bases:

>100_bases
CGCGCCGCCGAGCGGTTAAGATGGAAGCCTTTCCCGCGTCTGCCGAGGAGTTCCGATGCCTGCCCATCTCCATCTGTTGC
TGCCGCTCGCCGGCGTGCTG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MKLHQLQALVASAEAGSIRGAARTLGLSQAAVTRALRELEAAERLPLLVRAPEGIGFTEYGKALLTHAKLVLKQLEQAHD
DLARMRGRVDGRLSIGVTPWLTLTFLAETVLRFRERMPDVRLELYEALMAVAQPLLRDGSMDFALGHIHPGSGAQEFAFE
PMLRYDTAVMVRAGHPRERARSIHDLLDDDWVLNSTADGQTALVDYLFTRHGARIDERRIVRAQSVSMLQTMLEQADMCT
WCPTILAAVPSFGERMRALSLKETFEPRELGVVTRRSSTLSEAARCFIDCLLHVIRRHARSARKEDLALFKTVSLLI

Sequences:

>Translated_317_residues
MKLHQLQALVASAEAGSIRGAARTLGLSQAAVTRALRELEAAERLPLLVRAPEGIGFTEYGKALLTHAKLVLKQLEQAHD
DLARMRGRVDGRLSIGVTPWLTLTFLAETVLRFRERMPDVRLELYEALMAVAQPLLRDGSMDFALGHIHPGSGAQEFAFE
PMLRYDTAVMVRAGHPRERARSIHDLLDDDWVLNSTADGQTALVDYLFTRHGARIDERRIVRAQSVSMLQTMLEQADMCT
WCPTILAAVPSFGERMRALSLKETFEPRELGVVTRRSSTLSEAARCFIDCLLHVIRRHARSARKEDLALFKTVSLLI
>Mature_317_residues
MKLHQLQALVASAEAGSIRGAARTLGLSQAAVTRALRELEAAERLPLLVRAPEGIGFTEYGKALLTHAKLVLKQLEQAHD
DLARMRGRVDGRLSIGVTPWLTLTFLAETVLRFRERMPDVRLELYEALMAVAQPLLRDGSMDFALGHIHPGSGAQEFAFE
PMLRYDTAVMVRAGHPRERARSIHDLLDDDWVLNSTADGQTALVDYLFTRHGARIDERRIVRAQSVSMLQTMLEQADMCT
WCPTILAAVPSFGERMRALSLKETFEPRELGVVTRRSSTLSEAARCFIDCLLHVIRRHARSARKEDLALFKTVSLLI

Specific function: Could be the regulator of the abg operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787601, Length=278, Percent_Identity=28.0575539568345, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1789506, Length=290, Percent_Identity=24.1379310344828, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI157672245, Length=292, Percent_Identity=24.6575342465753, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI145693105, Length=295, Percent_Identity=20.6779661016949, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI87081904, Length=302, Percent_Identity=23.1788079470199, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788297, Length=161, Percent_Identity=29.1925465838509, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788887, Length=187, Percent_Identity=28.8770053475936, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1790262, Length=177, Percent_Identity=27.683615819209, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788296, Length=237, Percent_Identity=27.4261603375527, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35462; Mature: 35462

Theoretical pI: Translated: 8.65; Mature: 8.65

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLHQLQALVASAEAGSIRGAARTLGLSQAAVTRALRELEAAERLPLLVRAPEGIGFTEY
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHH
GKALLTHAKLVLKQLEQAHDDLARMRGRVDGRLSIGVTPWLTLTFLAETVLRFRERMPDV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCHH
RLELYEALMAVAQPLLRDGSMDFALGHIHPGSGAQEFAFEPMLRYDTAVMVRAGHPRERA
HHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHCCEEEEECCCCHHHH
RSIHDLLDDDWVLNSTADGQTALVDYLFTRHGARIDERRIVRAQSVSMLQTMLEQADMCT
HHHHHHHCCCCEECCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
WCPTILAAVPSFGERMRALSLKETFEPRELGVVTRRSSTLSEAARCFIDCLLHVIRRHAR
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
SARKEDLALFKTVSLLI
HHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MKLHQLQALVASAEAGSIRGAARTLGLSQAAVTRALRELEAAERLPLLVRAPEGIGFTEY
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHH
GKALLTHAKLVLKQLEQAHDDLARMRGRVDGRLSIGVTPWLTLTFLAETVLRFRERMPDV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCHH
RLELYEALMAVAQPLLRDGSMDFALGHIHPGSGAQEFAFEPMLRYDTAVMVRAGHPRERA
HHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHCCEEEEECCCCHHHH
RSIHDLLDDDWVLNSTADGQTALVDYLFTRHGARIDERRIVRAQSVSMLQTMLEQADMCT
HHHHHHHCCCCEECCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
WCPTILAAVPSFGERMRALSLKETFEPRELGVVTRRSSTLSEAARCFIDCLLHVIRRHAR
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
SARKEDLALFKTVSLLI
HHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 9829935 [H]