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The map label for this gene is tlyC [H]

Identifier: 189183989

GI number: 189183989

Start: 1114868

End: 1115782

Strand: Direct

Name: tlyC [H]

Synonym: OTT_1082

Alternate gene names: 189183989

Gene position: 1114868-1115782 (Clockwise)

Preceding gene: 189183988

Following gene: 189183991

Centisome position: 55.49

GC content: 29.51

Gene sequence:

>915_bases
ATGCAACTTAAACCTTTAGATAAAAAAGCAAAAAAGCACGTTATTGCCCATTATATAACAGCATTAAAAAACTGGTGTTT
CCAAATTTTAAGCAGGTTTCGGCTTATGTATAATGCTAAGTATAGGGAATTATATCATATTATTCAGGACCTTGAAATTA
ATGGTAATAAGATGTCTATAAGAGAGCAGATGTTACTCAGCAATTTCCTAAAATGCTATAACAAAAGCTTAGAAGAGATC
ATGATACCTAGATCTGATATTAAAGCAATTAAACTACCACTTACTCTTGATAAGTTAAAATCAATCATTACTCATACTTA
TCATACTCGTATATTAGTATATGAGAATAATCTTGATACTATTCTTGGGTTTGTACATATAAGAGATTTACTGCCTATAT
TGCTGGATGATAAGAACTTTACATTAAATTCCATTTTACGCCAACCTATTATTGCTGCTCAATCAATGAAAGTACTAGAT
TTGCTATCTGTTATGCAAAGAAAAAAAACATATATATCAATAGTAGTTGATGAATATGGTGGAACAGATGGCATAGTAAC
TACTGAAGATATTATAGAAAAAATATTTGATGGCATTGATCAGGAAGATAGTAGTTACTTTGATGCAAGGCCAGAATTTA
TATATCAAGTAGTTGATCAGCAAACTATTATTACAAGTGCGAGAGTAAGAATTGAAACATTAGAAAAAGCTATTGGCATT
CAATTAAAACAAGAAGAAGATGAATGTAATACTATTGGTGGCCTAGTACTTACTAGAATAGGACATATGCCATCTGTAGG
TTTTGTTGTAAACATTAACAAAAATATACAAGCTGAAATTGTTGATGCTACTCCTCGTATATTAAAACAAATTAAATTGA
CTATTCAAGATTGCGAAAAATCTAATATCTTATAG

Upstream 100 bases:

>100_bases
TGATCATCAACACGACAGTGAAGCTATAATTATGGAAGAGTTAGAAGTTAATTTACTTGCTAAATTTAGTATAGCATCAC
CATATTAGTAAGTATAACTG

Downstream 100 bases:

>100_bases
TTATTATTGTTTATATTTATCAAACATAAAATATCAAACTGTTGGAAAATTATGATTTCCACCTATTAAGGTTAATATCT
AAGTCAAATAAATCAAGTGC

Product: hemolysin C

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MQLKPLDKKAKKHVIAHYITALKNWCFQILSRFRLMYNAKYRELYHIIQDLEINGNKMSIREQMLLSNFLKCYNKSLEEI
MIPRSDIKAIKLPLTLDKLKSIITHTYHTRILVYENNLDTILGFVHIRDLLPILLDDKNFTLNSILRQPIIAAQSMKVLD
LLSVMQRKKTYISIVVDEYGGTDGIVTTEDIIEKIFDGIDQEDSSYFDARPEFIYQVVDQQTIITSARVRIETLEKAIGI
QLKQEEDECNTIGGLVLTRIGHMPSVGFVVNINKNIQAEIVDATPRILKQIKLTIQDCEKSNIL

Sequences:

>Translated_304_residues
MQLKPLDKKAKKHVIAHYITALKNWCFQILSRFRLMYNAKYRELYHIIQDLEINGNKMSIREQMLLSNFLKCYNKSLEEI
MIPRSDIKAIKLPLTLDKLKSIITHTYHTRILVYENNLDTILGFVHIRDLLPILLDDKNFTLNSILRQPIIAAQSMKVLD
LLSVMQRKKTYISIVVDEYGGTDGIVTTEDIIEKIFDGIDQEDSSYFDARPEFIYQVVDQQTIITSARVRIETLEKAIGI
QLKQEEDECNTIGGLVLTRIGHMPSVGFVVNINKNIQAEIVDATPRILKQIKLTIQDCEKSNIL
>Mature_304_residues
MQLKPLDKKAKKHVIAHYITALKNWCFQILSRFRLMYNAKYRELYHIIQDLEINGNKMSIREQMLLSNFLKCYNKSLEEI
MIPRSDIKAIKLPLTLDKLKSIITHTYHTRILVYENNLDTILGFVHIRDLLPILLDDKNFTLNSILRQPIIAAQSMKVLD
LLSVMQRKKTYISIVVDEYGGTDGIVTTEDIIEKIFDGIDQEDSSYFDARPEFIYQVVDQQTIITSARVRIETLEKAIGI
QLKQEEDECNTIGGLVLTRIGHMPSVGFVVNINKNIQAEIVDATPRILKQIKLTIQDCEKSNIL

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=224, Percent_Identity=27.6785714285714, Blast_Score=87, Evalue=2e-17,
Organism=Escherichia coli, GI1786879, Length=234, Percent_Identity=30.3418803418803, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI145693175, Length=246, Percent_Identity=27.6422764227642, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788119, Length=245, Percent_Identity=24.4897959183673, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI87082033, Length=233, Percent_Identity=26.6094420600858, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 35095; Mature: 35095

Theoretical pI: Translated: 7.98; Mature: 7.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLKPLDKKAKKHVIAHYITALKNWCFQILSRFRLMYNAKYRELYHIIQDLEINGNKMSI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
REQMLLSNFLKCYNKSLEEIMIPRSDIKAIKLPLTLDKLKSIITHTYHTRILVYENNLDT
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHEEEEEEECCHHH
ILGFVHIRDLLPILLDDKNFTLNSILRQPIIAAQSMKVLDLLSVMQRKKTYISIVVDEYG
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCC
GTDGIVTTEDIIEKIFDGIDQEDSSYFDARPEFIYQVVDQQTIITSARVRIETLEKAIGI
CCCCCEEHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QLKQEEDECNTIGGLVLTRIGHMPSVGFVVNINKNIQAEIVDATPRILKQIKLTIQDCEK
EEECCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHC
SNIL
CCCC
>Mature Secondary Structure
MQLKPLDKKAKKHVIAHYITALKNWCFQILSRFRLMYNAKYRELYHIIQDLEINGNKMSI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
REQMLLSNFLKCYNKSLEEIMIPRSDIKAIKLPLTLDKLKSIITHTYHTRILVYENNLDT
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHEEEEEEECCHHH
ILGFVHIRDLLPILLDDKNFTLNSILRQPIIAAQSMKVLDLLSVMQRKKTYISIVVDEYG
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCC
GTDGIVTTEDIIEKIFDGIDQEDSSYFDARPEFIYQVVDQQTIITSARVRIETLEKAIGI
CCCCCEEHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QLKQEEDECNTIGGLVLTRIGHMPSVGFVVNINKNIQAEIVDATPRILKQIKLTIQDCEK
EEECCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHC
SNIL
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA