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The map label for this gene is murB [H]

Identifier: 189183855

GI number: 189183855

Start: 992673

End: 993584

Strand: Direct

Name: murB [H]

Synonym: OTT_0948

Alternate gene names: 189183855

Gene position: 992673-993584 (Clockwise)

Preceding gene: 189183854

Following gene: 189183856

Centisome position: 49.41

GC content: 31.58

Gene sequence:

>912_bases
ATGTCTACAGTGATATCACTACCAAAAGTTAACGGTGAATATAGAAAAAATTTTAAACTATCTCACCTGACTTGGTTTAA
GGTTGGTGGAATTAGTCAAGTTTTTTATAAACCTAAAGATGAGCATGATCTGTCTTACTTTTTAGCAAATTTACAATCGA
ATATTAAAATTACTGTACTAGGAGCAGGATCAAATTTACTTATCAGAGATAATGGCATTGATGGTGTAACAATTAAATTA
GGTAGAAGTTTCAATGAGATTAATTTTGTTAAAAATAATCACTATAATATTATTAGTGTTGGAGCTGGAACTTTAAACTA
TGATGTTGCAAAATTTTGTCTACAACATAACTTAGGTGGTTTAGAATTTTTAGTAGGAATACCTGGCACAATAGGTGGGG
GGATTGCTATGAATGCTGGGGCTTATGGACAGGAATTTAAAGATGTTGTTTATTCTGTTGAGGCTTTAGATAGATCAGGT
AATAAGCATATATTTTTATCCAAAGATTTAAACTTTGAATATAGGCAATGCATTGTGAATGGCTTTTTAATCTTTACAAA
GACTAATCTCATTTGTTATAATGATAGTAAACCAAGTATTAGTCAAAAGCTACAAAAAATACAAACAGTGCGTAAATTAA
CGCAGCCAATTAACCAAAAAACTGCTGGTAGTGCTTTTCGTAATACTAACAACTATAAAGCTTGGCAGTTGATAGATAAG
GTAGGGTTACGTGGGCATAGTATTGGTGGTGCTCAAGTATCAAATCTACATTGCAATTTTTTAATTAATAATGGAAATGC
TACCGCTAGCGATATTGAAAATCTAGGGGAGTTGATTCGTAAAAAGGTTTTTGACCATACTGGTATAACATTAGAATGGG
AGATTAAAATTGTTGGGAAAAAAAGCCTATAG

Upstream 100 bases:

>100_bases
CAAGTTAAACCATATGATATTATTCTACTAATGGGAGCTGGAGATATTACTAAATTTGCAGCAATATTGCCACAGCAATT
ACAGGAATTATTAAAGCAGC

Downstream 100 bases:

>100_bases
TTTTCAAAGACACAATTCTGTTGTTGAAAGTATAACTAGTTCAGGCAAAAAGCATGTAGTAATCTTATATGGTGGAATGT
CAGCAGAAAGAGAGGTGTCA

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MSTVISLPKVNGEYRKNFKLSHLTWFKVGGISQVFYKPKDEHDLSYFLANLQSNIKITVLGAGSNLLIRDNGIDGVTIKL
GRSFNEINFVKNNHYNIISVGAGTLNYDVAKFCLQHNLGGLEFLVGIPGTIGGGIAMNAGAYGQEFKDVVYSVEALDRSG
NKHIFLSKDLNFEYRQCIVNGFLIFTKTNLICYNDSKPSISQKLQKIQTVRKLTQPINQKTAGSAFRNTNNYKAWQLIDK
VGLRGHSIGGAQVSNLHCNFLINNGNATASDIENLGELIRKKVFDHTGITLEWEIKIVGKKSL

Sequences:

>Translated_303_residues
MSTVISLPKVNGEYRKNFKLSHLTWFKVGGISQVFYKPKDEHDLSYFLANLQSNIKITVLGAGSNLLIRDNGIDGVTIKL
GRSFNEINFVKNNHYNIISVGAGTLNYDVAKFCLQHNLGGLEFLVGIPGTIGGGIAMNAGAYGQEFKDVVYSVEALDRSG
NKHIFLSKDLNFEYRQCIVNGFLIFTKTNLICYNDSKPSISQKLQKIQTVRKLTQPINQKTAGSAFRNTNNYKAWQLIDK
VGLRGHSIGGAQVSNLHCNFLINNGNATASDIENLGELIRKKVFDHTGITLEWEIKIVGKKSL
>Mature_302_residues
STVISLPKVNGEYRKNFKLSHLTWFKVGGISQVFYKPKDEHDLSYFLANLQSNIKITVLGAGSNLLIRDNGIDGVTIKLG
RSFNEINFVKNNHYNIISVGAGTLNYDVAKFCLQHNLGGLEFLVGIPGTIGGGIAMNAGAYGQEFKDVVYSVEALDRSGN
KHIFLSKDLNFEYRQCIVNGFLIFTKTNLICYNDSKPSISQKLQKIQTVRKLTQPINQKTAGSAFRNTNNYKAWQLIDKV
GLRGHSIGGAQVSNLHCNFLINNGNATASDIENLGELIRKKVFDHTGITLEWEIKIVGKKSL

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 33619; Mature: 33488

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTVISLPKVNGEYRKNFKLSHLTWFKVGGISQVFYKPKDEHDLSYFLANLQSNIKITVL
CCCEEECCCCCCHHHCCEEEEEEEEEEECCCEEEEECCCCCCHHHHHHHHHCCCEEEEEE
GAGSNLLIRDNGIDGVTIKLGRSFNEINFVKNNHYNIISVGAGTLNYDVAKFCLQHNLGG
ECCCEEEEEECCCCEEEEEECCCCCEEEEEECCCEEEEEECCCCCCHHHHHHHHHHCCCC
LEFLVGIPGTIGGGIAMNAGAYGQEFKDVVYSVEALDRSGNKHIFLSKDLNFEYRQCIVN
EEEEEECCCCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHH
GFLIFTKTNLICYNDSKPSISQKLQKIQTVRKLTQPINQKTAGSAFRNTNNYKAWQLIDK
CEEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCHHHHHHHH
VGLRGHSIGGAQVSNLHCNFLINNGNATASDIENLGELIRKKVFDHTGITLEWEIKIVGK
HCCCCCCCCCCEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEE
KSL
CCC
>Mature Secondary Structure 
STVISLPKVNGEYRKNFKLSHLTWFKVGGISQVFYKPKDEHDLSYFLANLQSNIKITVL
CCEEECCCCCCHHHCCEEEEEEEEEEECCCEEEEECCCCCCHHHHHHHHHCCCEEEEEE
GAGSNLLIRDNGIDGVTIKLGRSFNEINFVKNNHYNIISVGAGTLNYDVAKFCLQHNLGG
ECCCEEEEEECCCCEEEEEECCCCCEEEEEECCCEEEEEECCCCCCHHHHHHHHHHCCCC
LEFLVGIPGTIGGGIAMNAGAYGQEFKDVVYSVEALDRSGNKHIFLSKDLNFEYRQCIVN
EEEEEECCCCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHH
GFLIFTKTNLICYNDSKPSISQKLQKIQTVRKLTQPINQKTAGSAFRNTNNYKAWQLIDK
CEEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCHHHHHHHH
VGLRGHSIGGAQVSNLHCNFLINNGNATASDIENLGELIRKKVFDHTGITLEWEIKIVGK
HCCCCCCCCCCEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEE
KSL
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA