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The map label for this gene is nuoC [H]

Identifier: 189183820

GI number: 189183820

Start: 955448

End: 956038

Strand: Direct

Name: nuoC [H]

Synonym: OTT_0913

Alternate gene names: 189183820

Gene position: 955448-956038 (Clockwise)

Preceding gene: 189183819

Following gene: 189183821

Centisome position: 47.56

GC content: 28.6

Gene sequence:

>591_bases
ATGAAATTACATCACCTCAAAGAACTAAAAGAGCTAGTAGAAAGTCAATTTGCTATATCTAGCATTAGCGCTAAGTTTAA
TATTACCAATCACGTTGAAGCAATAATCCATAAGGAACAGTTAATTGAGGTTTTAAAATTACTCAAAAATGACAAAGAAT
TAAAATTTACAATACTAACAGATATTTTTGCAGCAGATTTTCCAGATAGGAATAAGAGATTTGAGATCGTATATAATTTA
CTTAGTATAATAAAAAATATCAGACTAATAGTTAAGATTAATCTTAATGACAATGAACTAATTCAATCAGCAACACCAGT
GTTTAGTAATGCAAACTGGTACGAACGTGAAATATATGATCTCTTTGGAATTAAATTTGCTAACCATCCACATTTAAAGC
GTATATTAACAGATTATGGATTTGTTGGCCATCCATTAAGAAAAGATTTTGCTCTTAGTGGATATTCTCAAGTAAAATAT
GATGATAAGTTAGAAAAAGTTGTATATGAACCTGTAAAATTAGATCAAGAATATCGAAATTTTAACTTTTCTTCTCCTTG
GCAAGGGCCAAAATCAACAATTCAAGACTAA

Upstream 100 bases:

>100_bases
TGTCCTCCTACCCCAGAAGCATTACTTTATGGTATTTTACAATTACAAAAAAAAATCAATAGAACTCAACAAGTCAAATT
TAAAAGATAGAGTGTAGTTT

Downstream 100 bases:

>100_bases
GTAATATTATAATGGCATTAAAAAAAAGGTCCAAACATTCTAAAAAATTCAAGTTAAATCTTGGGCCACAGCATCCTGCT
ACACATGGAGTATTACGGCT

Product: NADH dehydrogenase I chain C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C [H]

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MKLHHLKELKELVESQFAISSISAKFNITNHVEAIIHKEQLIEVLKLLKNDKELKFTILTDIFAADFPDRNKRFEIVYNL
LSIIKNIRLIVKINLNDNELIQSATPVFSNANWYEREIYDLFGIKFANHPHLKRILTDYGFVGHPLRKDFALSGYSQVKY
DDKLEKVVYEPVKLDQEYRNFNFSSPWQGPKSTIQD

Sequences:

>Translated_196_residues
MKLHHLKELKELVESQFAISSISAKFNITNHVEAIIHKEQLIEVLKLLKNDKELKFTILTDIFAADFPDRNKRFEIVYNL
LSIIKNIRLIVKINLNDNELIQSATPVFSNANWYEREIYDLFGIKFANHPHLKRILTDYGFVGHPLRKDFALSGYSQVKY
DDKLEKVVYEPVKLDQEYRNFNFSSPWQGPKSTIQD
>Mature_196_residues
MKLHHLKELKELVESQFAISSISAKFNITNHVEAIIHKEQLIEVLKLLKNDKELKFTILTDIFAADFPDRNKRFEIVYNL
LSIIKNIRLIVKINLNDNELIQSATPVFSNANWYEREIYDLFGIKFANHPHLKRILTDYGFVGHPLRKDFALSGYSQVKY
DDKLEKVVYEPVKLDQEYRNFNFSSPWQGPKSTIQD

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758788, Length=160, Percent_Identity=53.75, Blast_Score=186, Evalue=2e-47,
Organism=Escherichia coli, GI145693162, Length=167, Percent_Identity=35.3293413173653, Blast_Score=97, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI32563621, Length=164, Percent_Identity=47.5609756097561, Blast_Score=177, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI71990788, Length=164, Percent_Identity=47.5609756097561, Blast_Score=176, Evalue=7e-45,
Organism=Drosophila melanogaster, GI24656494, Length=184, Percent_Identity=45.1086956521739, Blast_Score=176, Evalue=6e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010218
- InterPro:   IPR001268
- ProDom:   PD001581 [H]

Pfam domain/function: PF00329 Complex1_30kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 23027; Mature: 23027

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLHHLKELKELVESQFAISSISAKFNITNHVEAIIHKEQLIEVLKLLKNDKELKFTILT
CCCHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHH
DIFAADFPDRNKRFEIVYNLLSIIKNIRLIVKINLNDNELIQSATPVFSNANWYEREIYD
HHHHCCCCCCCCHHHHHHHHHHHHHCCEEEEEEECCHHHHHHHCCCCCCCCCHHHHHHHH
LFGIKFANHPHLKRILTDYGFVGHPLRKDFALSGYSQVKYDDKLEKVVYEPVKLDQEYRN
HHCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHHC
FNFSSPWQGPKSTIQD
CCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKLHHLKELKELVESQFAISSISAKFNITNHVEAIIHKEQLIEVLKLLKNDKELKFTILT
CCCHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHH
DIFAADFPDRNKRFEIVYNLLSIIKNIRLIVKINLNDNELIQSATPVFSNANWYEREIYD
HHHHCCCCCCCCHHHHHHHHHHHHHCCEEEEEEECCHHHHHHHCCCCCCCCCHHHHHHHH
LFGIKFANHPHLKRILTDYGFVGHPLRKDFALSGYSQVKYDDKLEKVVYEPVKLDQEYRN
HHCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHHC
FNFSSPWQGPKSTIQD
CCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA