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The map label for this gene is nuoN2 [H]

Identifier: 189183726

GI number: 189183726

Start: 860191

End: 861681

Strand: Reverse

Name: nuoN2 [H]

Synonym: OTT_0819

Alternate gene names: 189183726

Gene position: 861681-860191 (Counterclockwise)

Preceding gene: 189183727

Following gene: 189183725

Centisome position: 42.89

GC content: 28.17

Gene sequence:

>1491_bases
ATGAGTAATATTTTTCAGGCTGTTAAAGATCATTTGGTGATATTAGAAGTTTTAATACCATTTTTTGGTAGTTTAATAGT
AGTATTATATAAAAAAGTTGAGTCAGCACTAATAGTATCCCGTTTATGTGCAATATTAGGAATAATATTAGGAATATATG
GTGTATTATCAATGATAAATTCCCCTCCATATTTTTATGCAATTGGCAATTGGCAGGCACCGATAGGTATAGAATATCGA
GTTGATCAGGTTAATCAAATAATTATCGTTTTTAGTTATTTTATTCTATTTTTATTACTAACATTTAATTCTCAGCTCAT
AAAAACAAACTTATTATCATCTCTTAATCCATCTCGATCTCATTTACTATATTCCATCTTACTATTATTGCACACAGGAT
TTTGTGGTATTATTCTCAGTAATGATTTATTTAATATTTACGTTTTTATAGAAATTGCTTCATTAGCAAGTTATACTTTG
GTTTCTCAGGGAGTTGATAAGCGAGCTTTAATTGGTAGTATTAATTATTTAATACTGGGTACTATTGGTGCTACTTTTAT
ACTTATTGCTATAGGATTCATATTGAGTAATACTGGCAGCTTGAATATTACTGATATAATTTCCATGTTACCACAACAAC
ATACAAAAACCTTAATTGCAGCAATAATGTTTTATATTACTGGATGCTTATTAAAGGTAGCTATGTTTCCTATGAGTTCA
TGGCTTATTAGTACTTATAAATATACTTCTTCAGTAATTTTATCATATTTTGCTCCAATTTCATGTATGGTTGGATTTTA
CATTCTACTATATTTTGTCTACCAAATTATTGGAACTACTAATATTAATACCTTGCATTCATATTATGTAATCAATGCCC
TAGGATTAGCAGGAGCAATTTTTTGTTCTTGTTATGCTGTTCAACAAAGCAACCTCAAATCAATTATGGCATATTCTGTA
TTAGCAGAAACAAGTTACATATCTCTAATGGCATTTAATATACAAAGCTCCACTATTGGGGCACAAATTATTGTTATATT
GTTAACTAGTTGTATACTTAAATCTATAATATATTCTTTAATTAGCAGAATAGAAGTATATTATCATGATAGCGAGCTTA
AACATATTGCAGGTATTGGATCGACTTATCCAGTGTTTGGTATATTATTTACATTAGCTTTAATCAGCAACTTGGGATTA
CCACTAACTATTGGCTTTGTTAATAAATTAAACATTTTTTTAACAGTTTTACAGTCACTTGGCTATTTTGGTATAATAAT
CTTGGCTATTAGTAGCTGCATGAGTTTTAATTATCATTATAAAATTTTTCATTATCTATATTCTACTCAGCAAACTTCTC
ATAGTAGCTTTACGCTTAATGGTAACAACAGCGTAGCAATAATTTTAACTATTATCAGCTATTTGATGCTAATATTTTAC
AATCACTTATTAGTATACTTACAGCCGTTTTTTCTACCAAAAATCATGTGA

Upstream 100 bases:

>100_bases
TCTGTAAGTCTTAGTATCATTCGTCAAATTTACCAAAGTTTTAATAGCTGTAATGAAAATGATATTCTATTAGAGCTACA
GAAAATGGAGCTAAAGCCAG

Downstream 100 bases:

>100_bases
GTTTTATAGATGCTTAAAAACATTATTTTATTATACAACGACATGATATGCTATATTCCATTTACTATAATTGGTATAAT
AGGTATATGGAATTTAATTA

Product: putative monovalent cation/H+ antiporter subunit D

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N; NDH-1 subunit N [H]

Number of amino acids: Translated: 496; Mature: 495

Protein sequence:

>496_residues
MSNIFQAVKDHLVILEVLIPFFGSLIVVLYKKVESALIVSRLCAILGIILGIYGVLSMINSPPYFYAIGNWQAPIGIEYR
VDQVNQIIIVFSYFILFLLLTFNSQLIKTNLLSSLNPSRSHLLYSILLLLHTGFCGIILSNDLFNIYVFIEIASLASYTL
VSQGVDKRALIGSINYLILGTIGATFILIAIGFILSNTGSLNITDIISMLPQQHTKTLIAAIMFYITGCLLKVAMFPMSS
WLISTYKYTSSVILSYFAPISCMVGFYILLYFVYQIIGTTNINTLHSYYVINALGLAGAIFCSCYAVQQSNLKSIMAYSV
LAETSYISLMAFNIQSSTIGAQIIVILLTSCILKSIIYSLISRIEVYYHDSELKHIAGIGSTYPVFGILFTLALISNLGL
PLTIGFVNKLNIFLTVLQSLGYFGIIILAISSCMSFNYHYKIFHYLYSTQQTSHSSFTLNGNNSVAIILTIISYLMLIFY
NHLLVYLQPFFLPKIM

Sequences:

>Translated_496_residues
MSNIFQAVKDHLVILEVLIPFFGSLIVVLYKKVESALIVSRLCAILGIILGIYGVLSMINSPPYFYAIGNWQAPIGIEYR
VDQVNQIIIVFSYFILFLLLTFNSQLIKTNLLSSLNPSRSHLLYSILLLLHTGFCGIILSNDLFNIYVFIEIASLASYTL
VSQGVDKRALIGSINYLILGTIGATFILIAIGFILSNTGSLNITDIISMLPQQHTKTLIAAIMFYITGCLLKVAMFPMSS
WLISTYKYTSSVILSYFAPISCMVGFYILLYFVYQIIGTTNINTLHSYYVINALGLAGAIFCSCYAVQQSNLKSIMAYSV
LAETSYISLMAFNIQSSTIGAQIIVILLTSCILKSIIYSLISRIEVYYHDSELKHIAGIGSTYPVFGILFTLALISNLGL
PLTIGFVNKLNIFLTVLQSLGYFGIIILAISSCMSFNYHYKIFHYLYSTQQTSHSSFTLNGNNSVAIILTIISYLMLIFY
NHLLVYLQPFFLPKIM
>Mature_495_residues
SNIFQAVKDHLVILEVLIPFFGSLIVVLYKKVESALIVSRLCAILGIILGIYGVLSMINSPPYFYAIGNWQAPIGIEYRV
DQVNQIIIVFSYFILFLLLTFNSQLIKTNLLSSLNPSRSHLLYSILLLLHTGFCGIILSNDLFNIYVFIEIASLASYTLV
SQGVDKRALIGSINYLILGTIGATFILIAIGFILSNTGSLNITDIISMLPQQHTKTLIAAIMFYITGCLLKVAMFPMSSW
LISTYKYTSSVILSYFAPISCMVGFYILLYFVYQIIGTTNINTLHSYYVINALGLAGAIFCSCYAVQQSNLKSIMAYSVL
AETSYISLMAFNIQSSTIGAQIIVILLTSCILKSIIYSLISRIEVYYHDSELKHIAGIGSTYPVFGILFTLALISNLGLP
LTIGFVNKLNIFLTVLQSLGYFGIIILAISSCMSFNYHYKIFHYLYSTQQTSHSSFTLNGNNSVAIILTIISYLMLIFYN
HLLVYLQPFFLPKIM

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translo

COG id: COG0651

COG function: function code CP; Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family [H]

Homologues:

Organism=Escherichia coli, GI145693160, Length=375, Percent_Identity=22.1333333333333, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788829, Length=495, Percent_Identity=22.8282828282828, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010096
- InterPro:   IPR001750
- InterPro:   IPR003918 [H]

Pfam domain/function: PF00361 Oxidored_q1 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 55290; Mature: 55159

Theoretical pI: Translated: 8.60; Mature: 8.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNIFQAVKDHLVILEVLIPFFGSLIVVLYKKVESALIVSRLCAILGIILGIYGVLSMIN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SPPYFYAIGNWQAPIGIEYRVDQVNQIIIVFSYFILFLLLTFNSQLIKTNLLSSLNPSRS
CCCEEEEECCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCHHH
HLLYSILLLLHTGFCGIILSNDLFNIYVFIEIASLASYTLVSQGVDKRALIGSINYLILG
HHHHHHHHHHHCCHHHEEECCCCEEEEHEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
TIGATFILIAIGFILSNTGSLNITDIISMLPQQHTKTLIAAIMFYITGCLLKVAMFPMSS
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WLISTYKYTSSVILSYFAPISCMVGFYILLYFVYQIIGTTNINTLHSYYVINALGLAGAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
FCSCYAVQQSNLKSIMAYSVLAETSYISLMAFNIQSSTIGAQIIVILLTSCILKSIIYSL
HHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
ISRIEVYYHDSELKHIAGIGSTYPVFGILFTLALISNLGLPLTIGFVNKLNIFLTVLQSL
HHHHHHEEECCHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHH
GYFGIIILAISSCMSFNYHYKIFHYLYSTQQTSHSSFTLNGNNSVAIILTIISYLMLIFY
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHH
NHLLVYLQPFFLPKIM
HHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SNIFQAVKDHLVILEVLIPFFGSLIVVLYKKVESALIVSRLCAILGIILGIYGVLSMIN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SPPYFYAIGNWQAPIGIEYRVDQVNQIIIVFSYFILFLLLTFNSQLIKTNLLSSLNPSRS
CCCEEEEECCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCHHH
HLLYSILLLLHTGFCGIILSNDLFNIYVFIEIASLASYTLVSQGVDKRALIGSINYLILG
HHHHHHHHHHHCCHHHEEECCCCEEEEHEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
TIGATFILIAIGFILSNTGSLNITDIISMLPQQHTKTLIAAIMFYITGCLLKVAMFPMSS
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WLISTYKYTSSVILSYFAPISCMVGFYILLYFVYQIIGTTNINTLHSYYVINALGLAGAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
FCSCYAVQQSNLKSIMAYSVLAETSYISLMAFNIQSSTIGAQIIVILLTSCILKSIIYSL
HHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
ISRIEVYYHDSELKHIAGIGSTYPVFGILFTLALISNLGLPLTIGFVNKLNIFLTVLQSL
HHHHHHEEECCHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHH
GYFGIIILAISSCMSFNYHYKIFHYLYSTQQTSHSSFTLNGNNSVAIILTIISYLMLIFY
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHH
NHLLVYLQPFFLPKIM
HHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA