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The map label for this gene is cysS [H]

Identifier: 189183685

GI number: 189183685

Start: 819178

End: 820614

Strand: Direct

Name: cysS [H]

Synonym: OTT_0778

Alternate gene names: 189183685

Gene position: 819178-820614 (Clockwise)

Preceding gene: 189183684

Following gene: 189183686

Centisome position: 40.78

GC content: 31.32

Gene sequence:

>1437_bases
ATGAACTTATATATTTATAACACCCTTTCTAGGAAAAAAGAAAGATTTGTTCCGTTAAACTGCAAATCAGTAAAAATGTA
TGTATGTGGTCCTACAGTATATGATATACCTCATATTGGCAATGCTCGTTCTGTTGTTGTATATGATCTTTTATATCGAG
TGCTAAGTTTGCTTTATGGTAGACAAAATATAACTTATGTAAGAAATATTACGGATATTGATGATAAAATTATAAATCGA
GCTAAAGAACTTAAGATTAGCATATTCAAATTAACACATGAAACTACAATTAAGTTTCACGAGGATATGTCATATCTAGG
GTGCTGCAATCCTACCATTGAACCAAAAGCGACAGATAATATTGATGTCATGATTAATATTATTACATCGTTAATTCAAA
CTGGTAATGCTTATAGTACTGATGATGGGCATGTATATTTTGCTGTTAAAACTTTTCAGGATTACAATCTACTATCACGC
CGCACATTTGATTCAATGATATTAAATAGTAGGGAAAGTTCTGAACCACAAAAGTCTTATTTTGCTGATTTTGTTTTGTG
GAAACCAGCTAATGCAGATAATGAAGATATAGATGCAGTTTTTGATAGTCCATGGGGGAAGGGGCGTCCTGGTTGGCATA
TTGAGTGTTCTGCTATGAGTTATAAATTTTTAGGAGAGAATTTTGATATACATGGTGGAGGAGCTGATTTAATATTTCCA
CATCATACTAATGAAATAGCTCAGAGTAGATGTGCTTTTCCTGAATCTCGTCATGCTTTATATTGGGTGCATAACGGATT
TTTAACTGTAAAAGGTGAAAAGATGAGTAAATCTTTGAATAATTTTGTTACTGTAAGAGATTTACAAAAACAAAATATTA
ACGGGGCAGCAGTAAGATTGATGTTTCTTAGTACACATTACCGAAAACCATTAGATTTTAATGATAAATCTTTAAATGAT
GCTAAAAACATTATTAATTATTTATATGATACTATTGATTCTGTAAACGGAACAGCGCAGCAACAAGATAACATCAAAGC
TGAATTTAAAGGTAATGCTTTTACTGTGGAGTTTATTAGTGCTCTGTTAGATGATTTAAATAGTCCTAAGGCAATTGCAT
GTTTATTGAATATTGCAAAACAAATCAGACGTCAAAATCAAAGTGAAGATAAGTTAGCTTTAACTCAGGCATTATTGTAT
GCAAGCAATTTATTAGGAATACTACATAATTATCAATTTATCAAAGACAGCAATGATGTGAAAGATAATAGCAATGTAAC
ACCTCATGAGATTGATTTATTAATTGCTAAGCGTATACAAGCTAAACAAGATAAGGATTGGAACTTAGCTGATCAGATTC
GTTCTCAACTACTAAGCAATGGAATTAGTTTAACTGATAAAGCAGATGGTACCACTAGTTGGAAGGTAATAAAATAG

Upstream 100 bases:

>100_bases
GATGAAGTTAGAGCAAGACTTCTAAGATATCAATAAACAAGAAAATTTAACAATTCAGGTACTCATATAATTAAGGACGA
TAAATATTAGAATATAGTAT

Downstream 100 bases:

>100_bases
CTTTAATGTAAAATTAAACATACGCTACGAATGGCATATAAACGCCAATTTAGGGTAAGGGGAAATATGGAAGGTAGTGA
ATAAAAGGTATACAAAGAGA

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 478; Mature: 478

Protein sequence:

>478_residues
MNLYIYNTLSRKKERFVPLNCKSVKMYVCGPTVYDIPHIGNARSVVVYDLLYRVLSLLYGRQNITYVRNITDIDDKIINR
AKELKISIFKLTHETTIKFHEDMSYLGCCNPTIEPKATDNIDVMINIITSLIQTGNAYSTDDGHVYFAVKTFQDYNLLSR
RTFDSMILNSRESSEPQKSYFADFVLWKPANADNEDIDAVFDSPWGKGRPGWHIECSAMSYKFLGENFDIHGGGADLIFP
HHTNEIAQSRCAFPESRHALYWVHNGFLTVKGEKMSKSLNNFVTVRDLQKQNINGAAVRLMFLSTHYRKPLDFNDKSLND
AKNIINYLYDTIDSVNGTAQQQDNIKAEFKGNAFTVEFISALLDDLNSPKAIACLLNIAKQIRRQNQSEDKLALTQALLY
ASNLLGILHNYQFIKDSNDVKDNSNVTPHEIDLLIAKRIQAKQDKDWNLADQIRSQLLSNGISLTDKADGTTSWKVIK

Sequences:

>Translated_478_residues
MNLYIYNTLSRKKERFVPLNCKSVKMYVCGPTVYDIPHIGNARSVVVYDLLYRVLSLLYGRQNITYVRNITDIDDKIINR
AKELKISIFKLTHETTIKFHEDMSYLGCCNPTIEPKATDNIDVMINIITSLIQTGNAYSTDDGHVYFAVKTFQDYNLLSR
RTFDSMILNSRESSEPQKSYFADFVLWKPANADNEDIDAVFDSPWGKGRPGWHIECSAMSYKFLGENFDIHGGGADLIFP
HHTNEIAQSRCAFPESRHALYWVHNGFLTVKGEKMSKSLNNFVTVRDLQKQNINGAAVRLMFLSTHYRKPLDFNDKSLND
AKNIINYLYDTIDSVNGTAQQQDNIKAEFKGNAFTVEFISALLDDLNSPKAIACLLNIAKQIRRQNQSEDKLALTQALLY
ASNLLGILHNYQFIKDSNDVKDNSNVTPHEIDLLIAKRIQAKQDKDWNLADQIRSQLLSNGISLTDKADGTTSWKVIK
>Mature_478_residues
MNLYIYNTLSRKKERFVPLNCKSVKMYVCGPTVYDIPHIGNARSVVVYDLLYRVLSLLYGRQNITYVRNITDIDDKIINR
AKELKISIFKLTHETTIKFHEDMSYLGCCNPTIEPKATDNIDVMINIITSLIQTGNAYSTDDGHVYFAVKTFQDYNLLSR
RTFDSMILNSRESSEPQKSYFADFVLWKPANADNEDIDAVFDSPWGKGRPGWHIECSAMSYKFLGENFDIHGGGADLIFP
HHTNEIAQSRCAFPESRHALYWVHNGFLTVKGEKMSKSLNNFVTVRDLQKQNINGAAVRLMFLSTHYRKPLDFNDKSLND
AKNIINYLYDTIDSVNGTAQQQDNIKAEFKGNAFTVEFISALLDDLNSPKAIACLLNIAKQIRRQNQSEDKLALTQALLY
ASNLLGILHNYQFIKDSNDVKDNSNVTPHEIDLLIAKRIQAKQDKDWNLADQIRSQLLSNGISLTDKADGTTSWKVIK

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=520, Percent_Identity=31.9230769230769, Blast_Score=241, Evalue=1e-63,
Organism=Homo sapiens, GI10835051, Length=265, Percent_Identity=33.2075471698113, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI21269877, Length=265, Percent_Identity=33.2075471698113, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI62240992, Length=265, Percent_Identity=33.2075471698113, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI303304987, Length=265, Percent_Identity=33.2075471698113, Blast_Score=153, Evalue=4e-37,
Organism=Escherichia coli, GI1786737, Length=477, Percent_Identity=42.1383647798742, Blast_Score=333, Evalue=1e-92,
Organism=Caenorhabditis elegans, GI17509795, Length=242, Percent_Identity=33.8842975206612, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17509797, Length=242, Percent_Identity=33.8842975206612, Blast_Score=140, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6324082, Length=301, Percent_Identity=34.5514950166113, Blast_Score=177, Evalue=4e-45,
Organism=Drosophila melanogaster, GI19922218, Length=505, Percent_Identity=32.0792079207921, Blast_Score=222, Evalue=4e-58,
Organism=Drosophila melanogaster, GI19922364, Length=247, Percent_Identity=38.0566801619433, Blast_Score=164, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 54455; Mature: 54455

Theoretical pI: Translated: 7.60; Mature: 7.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLYIYNTLSRKKERFVPLNCKSVKMYVCGPTVYDIPHIGNARSVVVYDLLYRVLSLLYG
CEEEEEECHHHHHHCCCCCCCCEEEEEEECCEEECCCCCCCCCHHHHHHHHHHHHHHHHC
RQNITYVRNITDIDDKIINRAKELKISIFKLTHETTIKFHEDMSYLGCCNPTIEPKATDN
CCCCEEEECCCCHHHHHHHHHHHCEEEEEEEECCCEEEECCCCCHHCCCCCCCCCCCCCC
IDVMINIITSLIQTGNAYSTDDGHVYFAVKTFQDYNLLSRRTFDSMILNSRESSEPQKSY
HHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCCCCCHHHHH
FADFVLWKPANADNEDIDAVFDSPWGKGRPGWHIECSAMSYKFLGENFDIHGGGADLIFP
HHEEEEECCCCCCCCCCHHHCCCCCCCCCCCCEEEEECEEEEECCCCEEECCCCCEEECC
HHTNEIAQSRCAFPESRHALYWVHNGFLTVKGEKMSKSLNNFVTVRDLQKQNINGAAVRL
CCCCHHHHHHCCCCCCCCEEEEEECCEEEEECHHHHHHHHHEEEEEHHHHCCCCHHHEEE
MFLSTHYRKPLDFNDKSLNDAKNIINYLYDTIDSVNGTAQQQDNIKAEFKGNAFTVEFIS
EEEHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCEEEHHHHH
ALLDDLNSPKAIACLLNIAKQIRRQNQSEDKLALTQALLYASNLLGILHNYQFIKDSNDV
HHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCC
KDNSNVTPHEIDLLIAKRIQAKQDKDWNLADQIRSQLLSNGISLTDKADGTTSWKVIK
CCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEECCCCCCCEEEEC
>Mature Secondary Structure
MNLYIYNTLSRKKERFVPLNCKSVKMYVCGPTVYDIPHIGNARSVVVYDLLYRVLSLLYG
CEEEEEECHHHHHHCCCCCCCCEEEEEEECCEEECCCCCCCCCHHHHHHHHHHHHHHHHC
RQNITYVRNITDIDDKIINRAKELKISIFKLTHETTIKFHEDMSYLGCCNPTIEPKATDN
CCCCEEEECCCCHHHHHHHHHHHCEEEEEEEECCCEEEECCCCCHHCCCCCCCCCCCCCC
IDVMINIITSLIQTGNAYSTDDGHVYFAVKTFQDYNLLSRRTFDSMILNSRESSEPQKSY
HHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCCCCCHHHHH
FADFVLWKPANADNEDIDAVFDSPWGKGRPGWHIECSAMSYKFLGENFDIHGGGADLIFP
HHEEEEECCCCCCCCCCHHHCCCCCCCCCCCCEEEEECEEEEECCCCEEECCCCCEEECC
HHTNEIAQSRCAFPESRHALYWVHNGFLTVKGEKMSKSLNNFVTVRDLQKQNINGAAVRL
CCCCHHHHHHCCCCCCCCEEEEEECCEEEEECHHHHHHHHHEEEEEHHHHCCCCHHHEEE
MFLSTHYRKPLDFNDKSLNDAKNIINYLYDTIDSVNGTAQQQDNIKAEFKGNAFTVEFIS
EEEHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCEEEHHHHH
ALLDDLNSPKAIACLLNIAKQIRRQNQSEDKLALTQALLYASNLLGILHNYQFIKDSNDV
HHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCC
KDNSNVTPHEIDLLIAKRIQAKQDKDWNLADQIRSQLLSNGISLTDKADGTTSWKVIK
CCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEECCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA