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The map label for this gene is mreB [H]

Identifier: 189183203

GI number: 189183203

Start: 304680

End: 305744

Strand: Direct

Name: mreB [H]

Synonym: OTT_0296

Alternate gene names: 189183203

Gene position: 304680-305744 (Clockwise)

Preceding gene: 189183202

Following gene: 189183204

Centisome position: 15.17

GC content: 35.59

Gene sequence:

>1065_bases
ATGGTTTTAAAGAAATATATTAAACAAGCAAAAGAAAAAATACTAAGTTTTTATTCTTCTAATATGGCTATTGATCTAGG
TACAGCTAATACACTTGTCTATGTACAAGGCAAAGGAATAGTATTAAATGAACCATCGGTTGTTGCATTGATTAGAGAAG
GAGGATCTTATAAGCCTTATGCATTTGGCCATGAAGCTAAAATGATGTTAGGTAAAACTCCATCAGATATTGAAGCTAAA
AGACCCCTGAAAGATGGTGTTATTGCTGATTTTAAAAGTGCTGAAGAAATGATTAAGCACTTTATTCATTCAGTACATAA
TCGTAGAAGCTTTGCTGGACCAGTAATAATTATATGTGTACCTTCAGGTTCAACACCAGTTGAGCGGCGTGCCATACAAG
AGGCAGCAGAAAGCGCTGGAGGACGTGAAGTATTTTTAATAGAAGAGCCAATGGCAGCAGCAATTGGAGCTGGATTGCCG
GTTACATCTCCAACTGGGTCAATGATAGTAGAAATTGGAGGTGGGACTACGCAAGTAGCTGTATTATCACTTGGTGGAGT
TGTATATTCAAAATCAGTACGAGTAGGTGGTGATAAAATGGATGAAGCAATATCTTCATATATCAGGCGCTATCATAACT
TGTTAATAGGAGATCCTACAGCAGAAAGAATAAAAAAGGAAATTGCAACAGCTTATGTTTCTAATACAGAAGCTAAAACT
ATTCAGATTAGAGGTCGAGATTTAATTAATGGTGTACCAAAAGGAATTACAATTTCTGAACAACAAATTGCTGAGAGTTT
AGTTGAGCCAGTAAATCAGATAATAGAAACAATCAAAGCTACACTTGAGTGTACACCTCCAGAGCTTTCTGCAGATATTG
CAGATAAAGGTATAGTGTTAAGCGGTGGAGGATCTTTAATTAAAAATTTAGACTTATTAATAAAAGAAACAACTCAATTG
CCAGTGTTCATTGCTGAAAATCCTTTATTTTGCGTAGCTTTGGGAAGCGGTGAAATCTTAGAAGACTTTGATAGATTAAA
GCATGTACTGTTTAAACAGCACTAA

Upstream 100 bases:

>100_bases
TTGTTAATTAATTTATTACGTAATGAATATTTTACGTTTACTTAAAAACAAGTGCAGTTATATTATATTTGTTAACTTAT
ATTTTTATTCTATATAGATT

Downstream 100 bases:

>100_bases
TTTTTTATGGCGCTTTTAGAAAATCGTTATAAGTACCAGAGCAAAAATATACTTAAACATTTAGTAACTGTATTAACAAA
ATTTCGCCTAGTTACAGCTA

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MVLKKYIKQAKEKILSFYSSNMAIDLGTANTLVYVQGKGIVLNEPSVVALIREGGSYKPYAFGHEAKMMLGKTPSDIEAK
RPLKDGVIADFKSAEEMIKHFIHSVHNRRSFAGPVIIICVPSGSTPVERRAIQEAAESAGGREVFLIEEPMAAAIGAGLP
VTSPTGSMIVEIGGGTTQVAVLSLGGVVYSKSVRVGGDKMDEAISSYIRRYHNLLIGDPTAERIKKEIATAYVSNTEAKT
IQIRGRDLINGVPKGITISEQQIAESLVEPVNQIIETIKATLECTPPELSADIADKGIVLSGGGSLIKNLDLLIKETTQL
PVFIAENPLFCVALGSGEILEDFDRLKHVLFKQH

Sequences:

>Translated_354_residues
MVLKKYIKQAKEKILSFYSSNMAIDLGTANTLVYVQGKGIVLNEPSVVALIREGGSYKPYAFGHEAKMMLGKTPSDIEAK
RPLKDGVIADFKSAEEMIKHFIHSVHNRRSFAGPVIIICVPSGSTPVERRAIQEAAESAGGREVFLIEEPMAAAIGAGLP
VTSPTGSMIVEIGGGTTQVAVLSLGGVVYSKSVRVGGDKMDEAISSYIRRYHNLLIGDPTAERIKKEIATAYVSNTEAKT
IQIRGRDLINGVPKGITISEQQIAESLVEPVNQIIETIKATLECTPPELSADIADKGIVLSGGGSLIKNLDLLIKETTQL
PVFIAENPLFCVALGSGEILEDFDRLKHVLFKQH
>Mature_354_residues
MVLKKYIKQAKEKILSFYSSNMAIDLGTANTLVYVQGKGIVLNEPSVVALIREGGSYKPYAFGHEAKMMLGKTPSDIEAK
RPLKDGVIADFKSAEEMIKHFIHSVHNRRSFAGPVIIICVPSGSTPVERRAIQEAAESAGGREVFLIEEPMAAAIGAGLP
VTSPTGSMIVEIGGGTTQVAVLSLGGVVYSKSVRVGGDKMDEAISSYIRRYHNLLIGDPTAERIKKEIATAYVSNTEAKT
IQIRGRDLINGVPKGITISEQQIAESLVEPVNQIIETIKATLECTPPELSADIADKGIVLSGGGSLIKNLDLLIKETTQL
PVFIAENPLFCVALGSGEILEDFDRLKHVLFKQH

Specific function: Involved in formation of the rod shape of the cell. May act as a negative regulator of ftsI [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI87082236, Length=347, Percent_Identity=56.1959654178674, Blast_Score=388, Evalue=1e-109,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001023
- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 38140; Mature: 38140

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLKKYIKQAKEKILSFYSSNMAIDLGTANTLVYVQGKGIVLNEPSVVALIREGGSYKPY
CCHHHHHHHHHHHHHHHHHCCEEEEECCCCEEEEEECCEEEECCCCEEEEEECCCCCCCE
AFGHEAKMMLGKTPSDIEAKRPLKDGVIADFKSAEEMIKHFIHSVHNRRSFAGPVIIICV
EECCCHHHEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEE
PSGSTPVERRAIQEAAESAGGREVFLIEEPMAAAIGAGLPVTSPTGSMIVEIGGGTTQVA
CCCCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHCCCCCCCCCCCCEEEEECCCCEEEE
VLSLGGVVYSKSVRVGGDKMDEAISSYIRRYHNLLIGDPTAERIKKEIATAYVSNTEAKT
EEECCCCEEECCEECCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEE
IQIRGRDLINGVPKGITISEQQIAESLVEPVNQIIETIKATLECTPPELSADIADKGIVL
EEEECCHHHCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEE
SGGGSLIKNLDLLIKETTQLPVFIAENPLFCVALGSGEILEDFDRLKHVLFKQH
ECCCHHHHHHHHHHHHCCCCEEEEECCCEEEEEECCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVLKKYIKQAKEKILSFYSSNMAIDLGTANTLVYVQGKGIVLNEPSVVALIREGGSYKPY
CCHHHHHHHHHHHHHHHHHCCEEEEECCCCEEEEEECCEEEECCCCEEEEEECCCCCCCE
AFGHEAKMMLGKTPSDIEAKRPLKDGVIADFKSAEEMIKHFIHSVHNRRSFAGPVIIICV
EECCCHHHEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEE
PSGSTPVERRAIQEAAESAGGREVFLIEEPMAAAIGAGLPVTSPTGSMIVEIGGGTTQVA
CCCCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHCCCCCCCCCCCCEEEEECCCCEEEE
VLSLGGVVYSKSVRVGGDKMDEAISSYIRRYHNLLIGDPTAERIKKEIATAYVSNTEAKT
EEECCCCEEECCEECCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEE
IQIRGRDLINGVPKGITISEQQIAESLVEPVNQIIETIKATLECTPPELSADIADKGIVL
EEEECCHHHCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEE
SGGGSLIKNLDLLIKETTQLPVFIAENPLFCVALGSGEILEDFDRLKHVLFKQH
ECCCHHHHHHHHHHHHCCCCEEEEECCCEEEEEECCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]