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The map label for this gene is gppA [C]

Identifier: 189183154

GI number: 189183154

Start: 237770

End: 239233

Strand: Reverse

Name: gppA [C]

Synonym: OTT_0247

Alternate gene names: 189183154

Gene position: 239233-237770 (Counterclockwise)

Preceding gene: 189183155

Following gene: 189183153

Centisome position: 11.91

GC content: 28.07

Gene sequence:

>1464_bases
ATGTATTACGCTGTAATGGATATTGGTTCAAATGCTATTAGAGCTGCTATATATAAAAACTTAAATATTGCTAGTGCTAA
AATTTACAGTGATAAATTTAAAGCCGATATTTGGTCCTTACTAGAATGTGATGATATAGATATAACACATCAATCATATC
TTATTATAGAGCATTTTATACATATTTTTAACCGGATTGGAGTTAAAAATGTAAAATGCGTTGCTACTGCTGTACTTAGA
TGGCATCATAAAGCATTAATATTTAAAGATATTATTCAACAAAGATATGGAATTGATATAGAAATTCTTTCAGGAGAACA
GGAAGCATATTTAACTACTATTGGTTTGATGCTTGGAATTCCTGATGTAGATGGAATTGTAGCTGACCTTGGAGGAGGGA
GCTTAGAATTGATTGAAGTACGACAGTCTAAAATTATTAGTTGTACTTCATTGCAGTTAGGTACTAAGATGCTTAATAAT
TTGAAAACTATTAGCATTGATTTTATTAAAGAGCAAATTCAAAAATTTAGTAATGTTGGTTATCAAAATCTATATTTGAT
TGGAGGAGCGTTTCGAATTATTACTAGATTTTATATGATGTTTATTAACTATCCTCTTATTAATACACACAACTTTAGAG
TTCAGGCTAATAATATTCTGTTATATATTGCTGAGTTAGACAGTATAGAAAATATTAATTCAAGTTATCGCAGCAGTAAA
TTTAAAGTAAATGCTCATGCAACAATGATATTACAGGCTTTAATAGAGGTTTTTAATATCAAAACTGTTGTAGTTTCTAA
TTATGGGCTTAAGGAAGGTGTGCATGTACGAAATTGCTTTTTACCTAACAATGAACAATTACCTGCCGATGTTGAAAAAC
TAAACAATAGTTTTATTAATTTTTTTCGTACTGTTAAAAATGATAACATGTTATATAAATACTGTTCTAAATTAGTTAAT
TTTCAGGAAGATGATTGTTACTTAGAGCAATATGTTAAAATGATTTTACCATTATTAATACAACCTAATGAAGCAATTGA
ACAAATTATTAGAGCATCTATTATTCTTGTAAATTATACTCAAGGGATCGATACATTGTTTAGAACAAGCTTTTTATCAG
AATATATTTTAACATCAGATTTACCATTTAGTCATAGTCAAAGAGTAATATTATCTCTAGTTTTAGCTAAGGCGGTTTCT
GATTCAAAATCAGTATTGCGTATTACTAAAATAGCAAAGCAAATTTTGCCAAAAACAGATTTTTGTAATAGTATGATTAT
CGGTACTGTAATTAGCCTTGCTAAAGATATTGATGGGTATCCTCTAAAAAGCCCATCATTTTTACTACCAGTAAATTATA
AATTTATTGAGCTTAGTACTACTTCTGTATTACCAAAGATGATTTGGACTAAAGTTGTTAGAAAGTTAAAAAAAATATGT
TCCCTTAGATCATATCGGCAATAA

Upstream 100 bases:

>100_bases
TTCTCCTTTTCATATTCTCGTGTTATGAATGAAATTACTACCAATTATTATAATATTGTAATATATATATAATGCTAAGT
CATTTATATAATATATACAT

Downstream 100 bases:

>100_bases
TTTCTGCAAAAAGCAGTCAAGAAACTGCTTAGTTATCATGCTTTATATGCTGAAAAGATTTAAAGTAGCCAAATACTAAT
GGCAACCAAAAACATTGGAT

Product: guanosine pentaphosphate phosphohydrolase

Products: (polyphosphate)n-1; phosphate

Alternate protein names: Exopolyphosphatase; Phosphatase Ppx/GppA Family; Guanosine Pentaphosphate Phosphohydrolase; Ppx/GppA Family Phosphatase; Ppx/Gppa Phosphatase; Ppx/GppA Phosphatase Family; Phosphatase; Guanosine Pentaphosphate Phosphohydrolase Gppa; Guanosine-5-Triphosphate 3'-Diphosphate Pyrophosphatase; Exopolyphosphatase Protein; Ppx/GppA Family Phosphotase; Ppx/GppA Phosphatase Family Protein; Bifunctional 3-Dehydroquinate Synthase/Phosphatase; Guanosine Pentaphosphate Phosphohydrolase GPPA; Nucleoside Diphosphate Kinase; Exopolyphosphatase Homolog; Exopolyphosphatase Ppx; Guanosine Pentaphosphate Phosphohydrolase Phage Proteinpa; Fumarate Reductase

Number of amino acids: Translated: 487; Mature: 487

Protein sequence:

>487_residues
MYYAVMDIGSNAIRAAIYKNLNIASAKIYSDKFKADIWSLLECDDIDITHQSYLIIEHFIHIFNRIGVKNVKCVATAVLR
WHHKALIFKDIIQQRYGIDIEILSGEQEAYLTTIGLMLGIPDVDGIVADLGGGSLELIEVRQSKIISCTSLQLGTKMLNN
LKTISIDFIKEQIQKFSNVGYQNLYLIGGAFRIITRFYMMFINYPLINTHNFRVQANNILLYIAELDSIENINSSYRSSK
FKVNAHATMILQALIEVFNIKTVVVSNYGLKEGVHVRNCFLPNNEQLPADVEKLNNSFINFFRTVKNDNMLYKYCSKLVN
FQEDDCYLEQYVKMILPLLIQPNEAIEQIIRASIILVNYTQGIDTLFRTSFLSEYILTSDLPFSHSQRVILSLVLAKAVS
DSKSVLRITKIAKQILPKTDFCNSMIIGTVISLAKDIDGYPLKSPSFLLPVNYKFIELSTTSVLPKMIWTKVVRKLKKIC
SLRSYRQ

Sequences:

>Translated_487_residues
MYYAVMDIGSNAIRAAIYKNLNIASAKIYSDKFKADIWSLLECDDIDITHQSYLIIEHFIHIFNRIGVKNVKCVATAVLR
WHHKALIFKDIIQQRYGIDIEILSGEQEAYLTTIGLMLGIPDVDGIVADLGGGSLELIEVRQSKIISCTSLQLGTKMLNN
LKTISIDFIKEQIQKFSNVGYQNLYLIGGAFRIITRFYMMFINYPLINTHNFRVQANNILLYIAELDSIENINSSYRSSK
FKVNAHATMILQALIEVFNIKTVVVSNYGLKEGVHVRNCFLPNNEQLPADVEKLNNSFINFFRTVKNDNMLYKYCSKLVN
FQEDDCYLEQYVKMILPLLIQPNEAIEQIIRASIILVNYTQGIDTLFRTSFLSEYILTSDLPFSHSQRVILSLVLAKAVS
DSKSVLRITKIAKQILPKTDFCNSMIIGTVISLAKDIDGYPLKSPSFLLPVNYKFIELSTTSVLPKMIWTKVVRKLKKIC
SLRSYRQ
>Mature_487_residues
MYYAVMDIGSNAIRAAIYKNLNIASAKIYSDKFKADIWSLLECDDIDITHQSYLIIEHFIHIFNRIGVKNVKCVATAVLR
WHHKALIFKDIIQQRYGIDIEILSGEQEAYLTTIGLMLGIPDVDGIVADLGGGSLELIEVRQSKIISCTSLQLGTKMLNN
LKTISIDFIKEQIQKFSNVGYQNLYLIGGAFRIITRFYMMFINYPLINTHNFRVQANNILLYIAELDSIENINSSYRSSK
FKVNAHATMILQALIEVFNIKTVVVSNYGLKEGVHVRNCFLPNNEQLPADVEKLNNSFINFFRTVKNDNMLYKYCSKLVN
FQEDDCYLEQYVKMILPLLIQPNEAIEQIIRASIILVNYTQGIDTLFRTSFLSEYILTSDLPFSHSQRVILSLVLAKAVS
DSKSVLRITKIAKQILPKTDFCNSMIIGTVISLAKDIDGYPLKSPSFLLPVNYKFIELSTTSVLPKMIWTKVVRKLKKIC
SLRSYRQ

Specific function: Conversion Of Pppgpp To Ppgpp. Guanosine Pentaphosphate (Pppgpp) Is A Cytoplasmic Signaling Molecule Which Together With Ppgpp Controls The "Stringent Response", An Adaptive Process That Allows Bacteria To Respond To Amino Acid Starvation, Resulting In T

COG id: COG0248

COG function: function code FP; Exopolyphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.6.1.11; 3.6.1.40

Molecular weight: Translated: 55605; Mature: 55605

Theoretical pI: Translated: 9.11; Mature: 9.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYYAVMDIGSNAIRAAIYKNLNIASAKIYSDKFKADIWSLLECDDIDITHQSYLIIEHFI
CEEEEEECCCHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
HIFNRIGVKNVKCVATAVLRWHHKALIFKDIIQQRYGIDIEILSGEQEAYLTTIGLMLGI
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHCC
PDVDGIVADLGGGSLELIEVRQSKIISCTSLQLGTKMLNNLKTISIDFIKEQIQKFSNVG
CCCCCHHEECCCCCEEEEEEHHHHHEEEHHHHHHHHHHCCCCEEHHHHHHHHHHHHHCCC
YQNLYLIGGAFRIITRFYMMFINYPLINTHNFRVQANNILLYIAELDSIENINSSYRSSK
CCEEEEEHHHHHHHHHHHHHHHCCCEEECCEEEEEECCEEEEEEECCCHHHCCHHHCCCC
FKVNAHATMILQALIEVFNIKTVVVSNYGLKEGVHVRNCFLPNNEQLPADVEKLNNSFIN
EEEEHHHHHHHHHHHHHHCCEEEEEECCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHH
FFRTVKNDNMLYKYCSKLVNFQEDDCYLEQYVKMILPLLIQPNEAIEQIIRASIILVNYT
HHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEEEEEEC
QGIDTLFRTSFLSEYILTSDLPFSHSQRVILSLVLAKAVSDSKSVLRITKIAKQILPKTD
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCH
FCNSMIIGTVISLAKDIDGYPLKSPSFLLPVNYKFIELSTTSVLPKMIWTKVVRKLKKIC
HHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCEEEEEEEHHHHHHHHHHHHHHHHHHHHH
SLRSYRQ
HHHHCCC
>Mature Secondary Structure
MYYAVMDIGSNAIRAAIYKNLNIASAKIYSDKFKADIWSLLECDDIDITHQSYLIIEHFI
CEEEEEECCCHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
HIFNRIGVKNVKCVATAVLRWHHKALIFKDIIQQRYGIDIEILSGEQEAYLTTIGLMLGI
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHCC
PDVDGIVADLGGGSLELIEVRQSKIISCTSLQLGTKMLNNLKTISIDFIKEQIQKFSNVG
CCCCCHHEECCCCCEEEEEEHHHHHEEEHHHHHHHHHHCCCCEEHHHHHHHHHHHHHCCC
YQNLYLIGGAFRIITRFYMMFINYPLINTHNFRVQANNILLYIAELDSIENINSSYRSSK
CCEEEEEHHHHHHHHHHHHHHHCCCEEECCEEEEEECCEEEEEEECCCHHHCCHHHCCCC
FKVNAHATMILQALIEVFNIKTVVVSNYGLKEGVHVRNCFLPNNEQLPADVEKLNNSFIN
EEEEHHHHHHHHHHHHHHCCEEEEEECCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHH
FFRTVKNDNMLYKYCSKLVNFQEDDCYLEQYVKMILPLLIQPNEAIEQIIRASIILVNYT
HHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEEEEEEC
QGIDTLFRTSFLSEYILTSDLPFSHSQRVILSLVLAKAVSDSKSVLRITKIAKQILPKTD
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCH
FCNSMIIGTVISLAKDIDGYPLKSPSFLLPVNYKFIELSTTSVLPKMIWTKVVRKLKKIC
HHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCEEEEEEEHHHHHHHHHHHHHHHHHHHHH
SLRSYRQ
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (polyphosphate)n; H2O

Specific reaction: (polyphosphate)n + H2O = (polyphosphate)n-1 + phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA