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The map label for this gene is slyD

Identifier: 189025582

GI number: 189025582

Start: 375075

End: 375605

Strand: Reverse

Name: slyD

Synonym: TPASS_0349

Alternate gene names: 189025582

Gene position: 375605-375075 (Counterclockwise)

Preceding gene: 189025586

Following gene: 189025581

Centisome position: 32.96

GC content: 57.63

Gene sequence:

>531_bases
ATGAAAATCGCAAATGAGTGTGTGGTGAACATCGAGTACACCCTGCGAGATGACACGGGGGAGATCATCGATTCTTCCGA
CGTGATGGGTGCGCTCGAGTATGTTCAGGGGCACGGCATGATCATTCCTGGCCTCGAGACCGCCTTAATTAACCGAGAAG
AGGGGGAGGAGTTTTCAGTAACCATTCCTCCGGTAGGAGCGTATGGAGAGGTGCAGGAGGACTTGCGCATGACAGTGGGG
CGAGATCAGTTTCCTCCAAACGTGCCAATAGAGGTGGGCATGCGGTTTGATGCAGGAAGCGGGGGTGACAGTCGACCGGT
GACCGTCACTGACGTGCAAGGTGAAACGATTATTGTAGATGGAAATCATCCCCTCGCGGGGAAGACGCTCCACTTTGAGG
TGGCTGTGCGCTCTGTGCGAGAGGCGACGGACGATGACTTAGCTGCACTTCTGTTTCGGGAAAGCACCAGCGGCGGTGGC
TGTGGGAGCGGCGCGGGAGGGTGCGGCTCGTGCGGAGCAGGCTGCCACTAG

Upstream 100 bases:

>100_bases
CCTCGCCCGGCTTATCCCCTATAACGGCGATTCTGTCAAGGGCACACGGCACAGAAACTGCCCTTGCCGTGAGTATCTTG
CCTGTGCTAGCATGCCGCGC

Downstream 100 bases:

>100_bases
ACGTACGCGATGAGTTAGTGTCGCTTTTAGGCGGCATGTGTTTCTTTCTCTCTACGGTTGAACACGTCATTCCAAAGCCG
CTGCCTTTCTTTCGCGTGGG

Product: peptidyl-prolyl cis-trans isomerase, FKBP-type

Products: NA

Alternate protein names: PPIase; Metallochaperone slyD

Number of amino acids: Translated: 176; Mature: 176

Protein sequence:

>176_residues
MKIANECVVNIEYTLRDDTGEIIDSSDVMGALEYVQGHGMIIPGLETALINREEGEEFSVTIPPVGAYGEVQEDLRMTVG
RDQFPPNVPIEVGMRFDAGSGGDSRPVTVTDVQGETIIVDGNHPLAGKTLHFEVAVRSVREATDDDLAALLFRESTSGGG
CGSGAGGCGSCGAGCH

Sequences:

>Translated_176_residues
MKIANECVVNIEYTLRDDTGEIIDSSDVMGALEYVQGHGMIIPGLETALINREEGEEFSVTIPPVGAYGEVQEDLRMTVG
RDQFPPNVPIEVGMRFDAGSGGDSRPVTVTDVQGETIIVDGNHPLAGKTLHFEVAVRSVREATDDDLAALLFRESTSGGG
CGSGAGGCGSCGAGCH
>Mature_176_residues
MKIANECVVNIEYTLRDDTGEIIDSSDVMGALEYVQGHGMIIPGLETALINREEGEEFSVTIPPVGAYGEVQEDLRMTVG
RDQFPPNVPIEVGMRFDAGSGGDSRPVTVTDVQGETIIVDGNHPLAGKTLHFEVAVRSVREATDDDLAALLFRESTSGGG
CGSGAGGCGSCGAGCH

Specific function: Also involved in hydrogenase metallocenter assembly, probably by participating in the nickel insertion step. This function in hydrogenase biosynthesis requires chaperone activity and the presence of the metal-binding domain, but not PPIase activity

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain

Homologues:

Organism=Escherichia coli, GI1789748, Length=148, Percent_Identity=42.5675675675676, Blast_Score=117, Evalue=4e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SLYD_TREPA (O83369)

Other databases:

- EMBL:   AE000520
- PIR:   D71336
- RefSeq:   NP_218789.1
- ProteinModelPortal:   O83369
- SMR:   O83369
- GeneID:   2611455
- GenomeReviews:   AE000520_GR
- KEGG:   tpa:TP0349
- NMPDR:   fig|243276.1.peg.348
- TIGR:   TP_0349
- HOGENOM:   HBG731200
- OMA:   WEEVVIA
- ProtClustDB:   CLSK218651
- BioCyc:   TPAL243276:TP_0349-MONOMER
- BRENDA:   5.2.1.8
- GO:   GO:0005737
- InterPro:   IPR001179
- PANTHER:   PTHR10516

Pfam domain/function: PF00254 FKBP_C

EC number: =5.2.1.8

Molecular weight: Translated: 18429; Mature: 18429

Theoretical pI: Translated: 4.06; Mature: 4.06

Prosite motif: PS50059 FKBP_PPIASE; PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIANECVVNIEYTLRDDTGEIIDSSDVMGALEYVQGHGMIIPGLETALINREEGEEFSV
CCCCCCEEEEEEEEEECCCCCEECCHHHHHHHHHHCCCCEECCCCCEEEEECCCCCEEEE
TIPPVGAYGEVQEDLRMTVGRDQFPPNVPIEVGMRFDAGSGGDSRPVTVTDVQGETIIVD
ECCCCCCCCCHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCCCCEEEEECCCCEEEEE
GNHPLAGKTLHFEVAVRSVREATDDDLAALLFRESTSGGGCGSGAGGCGSCGAGCH
CCCCCCCCEEEHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKIANECVVNIEYTLRDDTGEIIDSSDVMGALEYVQGHGMIIPGLETALINREEGEEFSV
CCCCCCEEEEEEEEEECCCCCEECCHHHHHHHHHHCCCCEECCCCCEEEEECCCCCEEEE
TIPPVGAYGEVQEDLRMTVGRDQFPPNVPIEVGMRFDAGSGGDSRPVTVTDVQGETIIVD
ECCCCCCCCCHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCCCCEEEEECCCCEEEEE
GNHPLAGKTLHFEVAVRSVREATDDDLAALLFRESTSGGGCGSGAGGCGSCGAGCH
CCCCCCCCEEEHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9665876