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The map label for this gene is ywlF [H]

Identifier: 188587449

GI number: 188587449

Start: 3090399

End: 3090887

Strand: Reverse

Name: ywlF [H]

Synonym: Nther_2859

Alternate gene names: 188587449

Gene position: 3090887-3090399 (Counterclockwise)

Preceding gene: 188587450

Following gene: 188587448

Centisome position: 97.64

GC content: 38.65

Gene sequence:

>489_bases
ATGACATATTTAACGCCGAAAAAAGTGCTAACTGAAACAGGTCAAATTCTTGGAATCGCCAGTGATCATGGTGGCCTGGA
ATTAAAACAAGAGATTATAAATCACTTACAAGATTCAGGTATAAAAATCGAAGACTTAGGTTGCTACCAGGATGAGTCGG
TGGATTATCCTGATTATGCAGAAAAACTTACACAAAAACTTGTGAATAATGAAATTTCATACGGGATATTAGTATGTGGG
ACGGGGATAGGTATTTCGATAAGTGCCAATAAAGTTCCCGGGATTAGAGCAGCCCTTTGTCATGACTGTTTCTCGGCCCG
TATGGCAAGAGAGCATAACGATGCAAATATTATTGCCCTTGGTGAAAGAATAATAGGAAAGGGTCTTGCTTTAGAAGTTG
TTGACACCTTCTTAAACAGTCCCTTTGGAGGCGGTCGCCATGAAAGGCGAGTAAATAAAATTACAAAGTTAGAACAAAAA
TACTCTTAA

Upstream 100 bases:

>100_bases
GGATAAATTTAGATAAACTTTTTCAAACAAGTTTATATCCGATAAAAAGCAGATACTGTAATATAACTTGTGATCACTAT
TAATCAGAAAGGGGATAATT

Downstream 100 bases:

>100_bases
AAGGAGGATCATTAATGGAAAACGTTAAAAAGACAGATCCAACTATTTTTTCTTGGATTGAAGAAGAATGGAAAAGACAG
GAGGAAGGTATTGAATTAAT

Product: ribose-5-phosphate isomerase

Products: D-ribulose 5-phosphate

Alternate protein names: NA

Number of amino acids: Translated: 162; Mature: 161

Protein sequence:

>162_residues
MTYLTPKKVLTETGQILGIASDHGGLELKQEIINHLQDSGIKIEDLGCYQDESVDYPDYAEKLTQKLVNNEISYGILVCG
TGIGISISANKVPGIRAALCHDCFSARMAREHNDANIIALGERIIGKGLALEVVDTFLNSPFGGGRHERRVNKITKLEQK
YS

Sequences:

>Translated_162_residues
MTYLTPKKVLTETGQILGIASDHGGLELKQEIINHLQDSGIKIEDLGCYQDESVDYPDYAEKLTQKLVNNEISYGILVCG
TGIGISISANKVPGIRAALCHDCFSARMAREHNDANIIALGERIIGKGLALEVVDTFLNSPFGGGRHERRVNKITKLEQK
YS
>Mature_161_residues
TYLTPKKVLTETGQILGIASDHGGLELKQEIINHLQDSGIKIEDLGCYQDESVDYPDYAEKLTQKLVNNEISYGILVCGT
GIGISISANKVPGIRAALCHDCFSARMAREHNDANIIALGERIIGKGLALEVVDTFLNSPFGGGRHERRVNKITKLEQKY
S

Specific function: In Addition To Its Activity On D-Ribose 5-Phosphate It Probably Also Has Activity On D-Allose 6-Phosphate. [C]

COG id: COG0698

COG function: function code G; Ribose 5-phosphate isomerase RpiB

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lacAB/rpiB family [H]

Homologues:

Organism=Escherichia coli, GI1790528, Length=144, Percent_Identity=44.4444444444444, Blast_Score=147, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003500
- InterPro:   IPR004785 [H]

Pfam domain/function: PF02502 LacAB_rpiB [H]

EC number: 5.3.1.6

Molecular weight: Translated: 17759; Mature: 17627

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYLTPKKVLTETGQILGIASDHGGLELKQEIINHLQDSGIKIEDLGCYQDESVDYPDYA
CCCCCHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCHHH
EKLTQKLVNNEISYGILVCGTGIGISISANKVPGIRAALCHDCFSARMAREHNDANIIAL
HHHHHHHHCCCCCCEEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEE
GERIIGKGLALEVVDTFLNSPFGGGRHERRVNKITKLEQKYS
CHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TYLTPKKVLTETGQILGIASDHGGLELKQEIINHLQDSGIKIEDLGCYQDESVDYPDYA
CCCCHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCHHH
EKLTQKLVNNEISYGILVCGTGIGISISANKVPGIRAALCHDCFSARMAREHNDANIIAL
HHHHHHHHCCCCCCEEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEE
GERIIGKGLALEVVDTFLNSPFGGGRHERRVNKITKLEQKYS
CHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 4.4 {D-ribose} 0.83 {D-ribose} [C]

Substrates: D-ribose 5-phosphate

Specific reaction: D-ribose 5-phosphate = D-ribulose 5-phosphate

General reaction: Intramolecular oxidoreduction; Isomerization [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]