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The map label for this gene is tsr [C]

Identifier: 188587450

GI number: 188587450

Start: 3090982

End: 3092649

Strand: Reverse

Name: tsr [C]

Synonym: Nther_2860

Alternate gene names: 188587450

Gene position: 3092649-3090982 (Counterclockwise)

Preceding gene: 188587451

Following gene: 188587449

Centisome position: 97.7

GC content: 38.79

Gene sequence:

>1668_bases
TTGGAAAATTCTACGGATCATCCTAAAAAGTATAAATCTTTAGGTATGGTTTTAGGAGTATTAGTGTTTATTTTAGCCGC
TGTCCCTTTGCTGACTTCTGCAATATTACTAGCGGTGCAAGATATGCTGGTAATCAGACCTTGGCAGATATTTGTGATTG
TAGGCATTACAGTTGTATTTGCACTTTTAGTTTATTTTTACATAAGATCCAGAGTCCTTGGTCCCTTATCATATTTGTTA
AAGGCCTGTGAACAGGCATCTCGCGGAGATTTGTTAAGGACAGTGGAACCAAGTTCACAAATCAGGGAAATTAGGCAAAT
AGAAGTTGGGATGGGTCAGTTATTTGGATCATTGCGTCAAATGGTAGGCAAAATTCAGATATCGGCAGAACAAACCCAGG
AGTATGCTAAGTCACTGGCTTCAGGTATAGAAGAAGCTAATGAAGCTATTAATCAGATTGCAACCACAGTCAACGATATT
TCTTCAGGAGCAGAAGAACAGTCTCAAGCAACAGATCAGACTCTTCAAGGAGTAAATGAACGCTTAGAACAAGTGGAACG
GATCTCAAGTAATGCAAAAAGTGCCCAAGAAACAGCTGAACAAATGGAACAAGTCATCGAAGATAGTTCCAGCAAAGTAG
AAAACTTAATCAAATCTTCTGAAGAAACCGCCGAAAACAATCAGAAGGCTAGAGAAATGATTAAGAAACTAACAGATCAA
GCAGAAAAAATTACTGAAATTGTGAATGTTGTTACTGATATATCAGAACAAACTCATCTCCTAGCTCTAAATGCGTCAAT
AGAAGCGGCCCGGGCTGGTGATTCAGGTCAAGGTTTTGCGGTAGTGGCACAAGAAGTCAGGAATTTGGCTGAGGAATCGG
GAAAATCAGCAGAAGAGATTTCAAATTTGATTTACAAAGTTAAAGAGATGGTTAATGAGGCGGATAGATTAGTTGAACAA
AGTGTTAACAATTCACGCCAGGGTGCTGAATATGCCGATACAGCCAGAAACGCTCTGAAAGAGATAGTAACTGCAGTTCA
TAGAGTAGCGGAAAAAGTTGATGATGTTCAGAGCGGAGCTCAGGTTCTAAAAGAAAGTATTCAGGAAGTTCAGGATTCTG
TTCAAAAGATTAACGAAATAGCTCAAAGTAATGCGGCAGGGGCAGAAGAAACCGCTGCATCTACTCAAGAGCATACAGCC
ACAATGGATGAAATGAATACATCTTCTGACAATTTGAGTAAGATTTCGGAGGAACTATTGCAGCTTGTGAATGAAACTCT
AGCCAGTGAAGAGGTCTACCAAAAATACCAAGATGGGATTAATGATATTAAAGAAAAACTCCAAGAAGCCTCTGAAAACT
TGAAAGAGATTGAAATTGACAAACAAGAACAAGACCCTTATTTAAATGAACTAGCTAATAATCCTAATGTTGAAATGTTA
TTTACTACCGATAGAGATGGGAAAATCGTCTATATTTCTCGAGATGTGGGTGTCTCCGATGTTTCTTATCGCCCCTGGTA
TAAAGAGGCTATTAAAGGAGAGGAATATATTTCGAATGTTTATATTTCACAGGCCAATGATCGTCCCTGTGTAACTGTAA
GTCTGCCCATTTTAGATGCATATGGTAGTGTAAAAGGTGTCCTGGGAGCTGATTTATTCTTAGGATAA

Upstream 100 bases:

>100_bases
AACCTATGATGAATATCAAGCTGTGTTTTTTGAATTAGAAGAGTTGATTGAGATTATTGTGAAGAACCATAACTAGTTTA
ATGTTTAAGGGGGATTTGGC

Downstream 100 bases:

>100_bases
ATTTAGATAAACTTTTTCAAACAAGTTTATATCCGATAAAAAGCAGATACTGTAATATAACTTGTGATCACTATTAATCA
GAAAGGGGATAATTATGACA

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 555; Mature: 555

Protein sequence:

>555_residues
MENSTDHPKKYKSLGMVLGVLVFILAAVPLLTSAILLAVQDMLVIRPWQIFVIVGITVVFALLVYFYIRSRVLGPLSYLL
KACEQASRGDLLRTVEPSSQIREIRQIEVGMGQLFGSLRQMVGKIQISAEQTQEYAKSLASGIEEANEAINQIATTVNDI
SSGAEEQSQATDQTLQGVNERLEQVERISSNAKSAQETAEQMEQVIEDSSSKVENLIKSSEETAENNQKAREMIKKLTDQ
AEKITEIVNVVTDISEQTHLLALNASIEAARAGDSGQGFAVVAQEVRNLAEESGKSAEEISNLIYKVKEMVNEADRLVEQ
SVNNSRQGAEYADTARNALKEIVTAVHRVAEKVDDVQSGAQVLKESIQEVQDSVQKINEIAQSNAAGAEETAASTQEHTA
TMDEMNTSSDNLSKISEELLQLVNETLASEEVYQKYQDGINDIKEKLQEASENLKEIEIDKQEQDPYLNELANNPNVEML
FTTDRDGKIVYISRDVGVSDVSYRPWYKEAIKGEEYISNVYISQANDRPCVTVSLPILDAYGSVKGVLGADLFLG

Sequences:

>Translated_555_residues
MENSTDHPKKYKSLGMVLGVLVFILAAVPLLTSAILLAVQDMLVIRPWQIFVIVGITVVFALLVYFYIRSRVLGPLSYLL
KACEQASRGDLLRTVEPSSQIREIRQIEVGMGQLFGSLRQMVGKIQISAEQTQEYAKSLASGIEEANEAINQIATTVNDI
SSGAEEQSQATDQTLQGVNERLEQVERISSNAKSAQETAEQMEQVIEDSSSKVENLIKSSEETAENNQKAREMIKKLTDQ
AEKITEIVNVVTDISEQTHLLALNASIEAARAGDSGQGFAVVAQEVRNLAEESGKSAEEISNLIYKVKEMVNEADRLVEQ
SVNNSRQGAEYADTARNALKEIVTAVHRVAEKVDDVQSGAQVLKESIQEVQDSVQKINEIAQSNAAGAEETAASTQEHTA
TMDEMNTSSDNLSKISEELLQLVNETLASEEVYQKYQDGINDIKEKLQEASENLKEIEIDKQEQDPYLNELANNPNVEML
FTTDRDGKIVYISRDVGVSDVSYRPWYKEAIKGEEYISNVYISQANDRPCVTVSLPILDAYGSVKGVLGADLFLG
>Mature_555_residues
MENSTDHPKKYKSLGMVLGVLVFILAAVPLLTSAILLAVQDMLVIRPWQIFVIVGITVVFALLVYFYIRSRVLGPLSYLL
KACEQASRGDLLRTVEPSSQIREIRQIEVGMGQLFGSLRQMVGKIQISAEQTQEYAKSLASGIEEANEAINQIATTVNDI
SSGAEEQSQATDQTLQGVNERLEQVERISSNAKSAQETAEQMEQVIEDSSSKVENLIKSSEETAENNQKAREMIKKLTDQ
AEKITEIVNVVTDISEQTHLLALNASIEAARAGDSGQGFAVVAQEVRNLAEESGKSAEEISNLIYKVKEMVNEADRLVEQ
SVNNSRQGAEYADTARNALKEIVTAVHRVAEKVDDVQSGAQVLKESIQEVQDSVQKINEIAQSNAAGAEETAASTQEHTA
TMDEMNTSSDNLSKISEELLQLVNETLASEEVYQKYQDGINDIKEKLQEASENLKEIEIDKQEQDPYLNELANNPNVEML
FTTDRDGKIVYISRDVGVSDVSYRPWYKEAIKGEEYISNVYISQANDRPCVTVSLPILDAYGSVKGVLGADLFLG

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Homo sapiens, GI119466532, Length=333, Percent_Identity=23.4234234234234, Blast_Score=66, Evalue=9e-11,
Organism=Homo sapiens, GI28559088, Length=333, Percent_Identity=23.4234234234234, Blast_Score=66, Evalue=9e-11,
Organism=Escherichia coli, GI2367378, Length=333, Percent_Identity=29.7297297297297, Blast_Score=136, Evalue=4e-33,
Organism=Escherichia coli, GI1788194, Length=367, Percent_Identity=27.7929155313352, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1787690, Length=358, Percent_Identity=27.6536312849162, Blast_Score=122, Evalue=9e-29,
Organism=Escherichia coli, GI1788195, Length=339, Percent_Identity=28.3185840707965, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1789453, Length=385, Percent_Identity=23.3766233766234, Blast_Score=94, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 61181; Mature: 61181

Theoretical pI: Translated: 4.25; Mature: 4.25

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENSTDHPKKYKSLGMVLGVLVFILAAVPLLTSAILLAVQDMLVIRPWQIFVIVGITVVF
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
ALLVYFYIRSRVLGPLSYLLKACEQASRGDLLRTVEPSSQIREIRQIEVGMGQLFGSLRQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
MVGKIQISAEQTQEYAKSLASGIEEANEAINQIATTVNDISSGAEEQSQATDQTLQGVNE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
RLEQVERISSNAKSAQETAEQMEQVIEDSSSKVENLIKSSEETAENNQKAREMIKKLTDQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
AEKITEIVNVVTDISEQTHLLALNASIEAARAGDSGQGFAVVAQEVRNLAEESGKSAEEI
HHHHHHHHHHHHHHCCCCEEEEECCCHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHH
SNLIYKVKEMVNEADRLVEQSVNNSRQGAEYADTARNALKEIVTAVHRVAEKVDDVQSGA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVLKESIQEVQDSVQKINEIAQSNAAGAEETAASTQEHTATMDEMNTSSDNLSKISEELL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
QLVNETLASEEVYQKYQDGINDIKEKLQEASENLKEIEIDKQEQDPYLNELANNPNVEML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCEEEE
FTTDRDGKIVYISRDVGVSDVSYRPWYKEAIKGEEYISNVYISQANDRPCVTVSLPILDA
EEECCCCEEEEEECCCCCCCCCCCCHHHHHHCHHHHHHHHHHCCCCCCCEEEEECHHHHH
YGSVKGVLGADLFLG
HHHHHHHHHHHHHCC
>Mature Secondary Structure
MENSTDHPKKYKSLGMVLGVLVFILAAVPLLTSAILLAVQDMLVIRPWQIFVIVGITVVF
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
ALLVYFYIRSRVLGPLSYLLKACEQASRGDLLRTVEPSSQIREIRQIEVGMGQLFGSLRQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
MVGKIQISAEQTQEYAKSLASGIEEANEAINQIATTVNDISSGAEEQSQATDQTLQGVNE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
RLEQVERISSNAKSAQETAEQMEQVIEDSSSKVENLIKSSEETAENNQKAREMIKKLTDQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
AEKITEIVNVVTDISEQTHLLALNASIEAARAGDSGQGFAVVAQEVRNLAEESGKSAEEI
HHHHHHHHHHHHHHCCCCEEEEECCCHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHH
SNLIYKVKEMVNEADRLVEQSVNNSRQGAEYADTARNALKEIVTAVHRVAEKVDDVQSGA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVLKESIQEVQDSVQKINEIAQSNAAGAEETAASTQEHTATMDEMNTSSDNLSKISEELL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
QLVNETLASEEVYQKYQDGINDIKEKLQEASENLKEIEIDKQEQDPYLNELANNPNVEML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCEEEE
FTTDRDGKIVYISRDVGVSDVSYRPWYKEAIKGEEYISNVYISQANDRPCVTVSLPILDA
EEECCCCEEEEEECCCCCCCCCCCCHHHHHHCHHHHHHHHHHCCCCCCCEEEEECHHHHH
YGSVKGVLGADLFLG
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA