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The map label for this gene is appB [H]

Identifier: 188587380

GI number: 188587380

Start: 3012614

End: 3013534

Strand: Reverse

Name: appB [H]

Synonym: Nther_2789

Alternate gene names: 188587380

Gene position: 3013534-3012614 (Counterclockwise)

Preceding gene: 188587381

Following gene: 188587379

Centisome position: 95.2

GC content: 37.79

Gene sequence:

>921_bases
ATGGTGGCTAATTATATTCTAAGAAGAATACTACAACTAATCCCTGTGATTTTTATAATTTCTTTTGTTGTATTTTGCCT
GGTATACGTTGCTGGTGACCCTGTAACTATGATGCTGCCAGAAGAAGCAACCCAGGAAGAGGTAGAGGCCATGAGGGAAT
CTCTTGGCCTCAATGACCCTTTCATGGTTCAATATGGTCGCTTTCTTATTAATATGCTACAGGGAGACTTTGGCGAATCA
TATCGTTATAATGAACAGGCTTTACCTATTGTGATGTCCCGTATTCCTGCCACTTTGGAGTTAACGGTATCAGCCATGGT
AGTAGCGACAGTAATTGCAGTGCCTTTAGGGATTTGGTCTGCAGTCAATAAAAATTCATTTTTAGATATTTTTGTAACAG
GTGGAGCTGTCCTGGGAAAAGCTATGCCAAACTTTTGGTTAGGTATTATGTTGATTTTAATTTTTTCAGTTAATTTAAGG
ATATTTCCAGTATCTGGGCGGGGCACCTTGTTACATTTAGTCTTACCAGCTATTACTCTTGGTACAGCCATTGCAGCGGA
CATGGCCCGCCTAATTCGATCAAGTATGATTGAAATTATGAATCAAGATTATATTAAAACAGCTAAAAGTAAAGGGCTTA
AAAAGCCGTTGATTGTCTATATTCACGCTTTTAAAAATGCATTGATACCTGTAATAACTATTATGGCCCTTCAAGTTTCG
ATTCTGGTTGGGGGAACTTTGATTACTGAAACGGTATTTGCCTGGCCGGGTCTTGGACAACTATTAATCCAAGCTGTTAA
TACCAGAGATATGGCAATTGTTCAGGCAGCAGTTATGATAATTTCTTTTATGGTCATAATCGTGAATTTATTGGCAGATA
TTTTATACGGATTTGTTGATCCAAGGATAAATTACAGTTAA

Upstream 100 bases:

>100_bases
AAAGGATAGTTACGGTATAAACAATCGAATTGACTTCGAACCCCGTTTGGATGAAATGATTTACATTCCGGAAATTGGTA
AAACAGACTAGAGGTGATGA

Downstream 100 bases:

>100_bases
TGAAAGGAGGGCTCCTAATGGCTCAAAGTACTGATATCAACAATTCAGATCACCGTGAAAATGGATCTGGAATCATCAAT
AGTTTACAAGAAAAAGATTA

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MVANYILRRILQLIPVIFIISFVVFCLVYVAGDPVTMMLPEEATQEEVEAMRESLGLNDPFMVQYGRFLINMLQGDFGES
YRYNEQALPIVMSRIPATLELTVSAMVVATVIAVPLGIWSAVNKNSFLDIFVTGGAVLGKAMPNFWLGIMLILIFSVNLR
IFPVSGRGTLLHLVLPAITLGTAIAADMARLIRSSMIEIMNQDYIKTAKSKGLKKPLIVYIHAFKNALIPVITIMALQVS
ILVGGTLITETVFAWPGLGQLLIQAVNTRDMAIVQAAVMIISFMVIIVNLLADILYGFVDPRINYS

Sequences:

>Translated_306_residues
MVANYILRRILQLIPVIFIISFVVFCLVYVAGDPVTMMLPEEATQEEVEAMRESLGLNDPFMVQYGRFLINMLQGDFGES
YRYNEQALPIVMSRIPATLELTVSAMVVATVIAVPLGIWSAVNKNSFLDIFVTGGAVLGKAMPNFWLGIMLILIFSVNLR
IFPVSGRGTLLHLVLPAITLGTAIAADMARLIRSSMIEIMNQDYIKTAKSKGLKKPLIVYIHAFKNALIPVITIMALQVS
ILVGGTLITETVFAWPGLGQLLIQAVNTRDMAIVQAAVMIISFMVIIVNLLADILYGFVDPRINYS
>Mature_306_residues
MVANYILRRILQLIPVIFIISFVVFCLVYVAGDPVTMMLPEEATQEEVEAMRESLGLNDPFMVQYGRFLINMLQGDFGES
YRYNEQALPIVMSRIPATLELTVSAMVVATVIAVPLGIWSAVNKNSFLDIFVTGGAVLGKAMPNFWLGIMLILIFSVNLR
IFPVSGRGTLLHLVLPAITLGTAIAADMARLIRSSMIEIMNQDYIKTAKSKGLKKPLIVYIHAFKNALIPVITIMALQVS
ILVGGTLITETVFAWPGLGQLLIQAVNTRDMAIVQAAVMIISFMVIIVNLLADILYGFVDPRINYS

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=304, Percent_Identity=39.8026315789474, Blast_Score=246, Evalue=2e-66,
Organism=Escherichia coli, GI1789965, Length=336, Percent_Identity=38.6904761904762, Blast_Score=242, Evalue=2e-65,
Organism=Escherichia coli, GI1789888, Length=305, Percent_Identity=36.3934426229508, Blast_Score=209, Evalue=1e-55,
Organism=Escherichia coli, GI1787497, Length=308, Percent_Identity=34.0909090909091, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI1787761, Length=317, Percent_Identity=36.5930599369085, Blast_Score=179, Evalue=3e-46,
Organism=Escherichia coli, GI1787550, Length=263, Percent_Identity=34.6007604562738, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1788504, Length=359, Percent_Identity=24.5125348189415, Blast_Score=120, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 33713; Mature: 33713

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVANYILRRILQLIPVIFIISFVVFCLVYVAGDPVTMMLPEEATQEEVEAMRESLGLNDP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHCCCCCC
FMVQYGRFLINMLQGDFGESYRYNEQALPIVMSRIPATLELTVSAMVVATVIAVPLGIWS
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
AVNKNSFLDIFVTGGAVLGKAMPNFWLGIMLILIFSVNLRIFPVSGRGTLLHLVLPAITL
HCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHH
GTAIAADMARLIRSSMIEIMNQDYIKTAKSKGLKKPLIVYIHAFKNALIPVITIMALQVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ILVGGTLITETVFAWPGLGQLLIQAVNTRDMAIVQAAVMIISFMVIIVNLLADILYGFVD
HHHCHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PRINYS
CCCCCC
>Mature Secondary Structure
MVANYILRRILQLIPVIFIISFVVFCLVYVAGDPVTMMLPEEATQEEVEAMRESLGLNDP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHCCCCCC
FMVQYGRFLINMLQGDFGESYRYNEQALPIVMSRIPATLELTVSAMVVATVIAVPLGIWS
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
AVNKNSFLDIFVTGGAVLGKAMPNFWLGIMLILIFSVNLRIFPVSGRGTLLHLVLPAITL
HCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHH
GTAIAADMARLIRSSMIEIMNQDYIKTAKSKGLKKPLIVYIHAFKNALIPVITIMALQVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ILVGGTLITETVFAWPGLGQLLIQAVNTRDMAIVQAAVMIISFMVIIVNLLADILYGFVD
HHHCHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PRINYS
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]