Click here to switch to the map view.

The map label for this gene is nadA [H]

Identifier: 188587021

GI number: 188587021

Start: 2585766

End: 2586692

Strand: Direct

Name: nadA [H]

Synonym: Nther_2413

Alternate gene names: 188587021

Gene position: 2585766-2586692 (Clockwise)

Preceding gene: 188587020

Following gene: 188587022

Centisome position: 81.68

GC content: 38.94

Gene sequence:

>927_bases
ATGAATAAATTTAATACTAGTCAAGAGGAAGTTTTAAAGCAAATCCGCGACTTAAAAAAACAGGTTGATGCCATCATCTT
GGCTCATAATTACCAACTTCCCCAAGTTCAAAAAGTAGCAGATTTCGTAGGAGATTCCTTTGAACTCTGTAAAACAGCTC
GGGAAGTGGATAGTTCAGTGATTATATTTTGTGGGGTTCATTTCATGGCAGAAGGAGCTAAAGTCCTGGCACCGGAAAAA
CAGGTGATTATCCCAGACAATAATGCAGGATGTCCTCTGGCAGACATGGCTAGTCCAGAACAGGTTAGAGAGATAAAGAA
AGAGTTTCCTGAAACCCCTGTAGTGGCGTATGTTAATACCAGTGCCGAAGTTAAAGCTGAAAGCCACATTTGTTGTACTT
CATCTAATGCAGTGGATGTAGTTAATTCCCTCGATTCTGATTCTGTTATCTTTTTACCAGATCAAAATCTAGCTGATTAT
GTATCTAAATATACCGATAAACAGGTGATTCCATGGAATGGCTATTGTATTTCCCATGTACGAGTATCTACTGAAGAAAT
AGAAGAGACGAGAAAATATTATCCTGAAGCACCCATATTAGTACATCCTGAATGTCCTCACGAAATTAAAGAAACAGCCG
ATTATATCATGGGCACTGGAGGTATGGTGAAATTCGCCAGAGAAACAGAACATTCCACTATGATTATCGGAACAGAAGAA
GGATTAGTTCATCGGTTGAAGAGAGAAAATCCCGCTAAAAACTTTTATCTACTAAGCCCAAGCTTTTTCTGTTCTAATAT
GAAAAAAATCACACCTCAGGAAGTGCTCCACTCCTTAAAAAACTTGGCTCCAGAAATAGAAGTAGCGGAAGAAACGCGGG
TCAAGGCATATCAAGCCTTGAATAACATGTTGAGAGCTACACAATAA

Upstream 100 bases:

>100_bases
ATCATTTGTGTTTACATGCATAGGACAGTCATTAACTAAGAAAGTGATAACTTTCTTTTCATATATAAACTCAATTAATT
ATACAAGGGAGAGGTGAACT

Downstream 100 bases:

>100_bases
AAACAGTAACGATTACATTAGGAACTTGGAATAGATAGATCACGATAGGCTTTAGGATTAGTTTTATACTAATTTCAGAA
GTAGGATTAGGAATAAGATT

Product: quinolinate synthetase complex, A subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MNKFNTSQEEVLKQIRDLKKQVDAIILAHNYQLPQVQKVADFVGDSFELCKTAREVDSSVIIFCGVHFMAEGAKVLAPEK
QVIIPDNNAGCPLADMASPEQVREIKKEFPETPVVAYVNTSAEVKAESHICCTSSNAVDVVNSLDSDSVIFLPDQNLADY
VSKYTDKQVIPWNGYCISHVRVSTEEIEETRKYYPEAPILVHPECPHEIKETADYIMGTGGMVKFARETEHSTMIIGTEE
GLVHRLKRENPAKNFYLLSPSFFCSNMKKITPQEVLHSLKNLAPEIEVAEETRVKAYQALNNMLRATQ

Sequences:

>Translated_308_residues
MNKFNTSQEEVLKQIRDLKKQVDAIILAHNYQLPQVQKVADFVGDSFELCKTAREVDSSVIIFCGVHFMAEGAKVLAPEK
QVIIPDNNAGCPLADMASPEQVREIKKEFPETPVVAYVNTSAEVKAESHICCTSSNAVDVVNSLDSDSVIFLPDQNLADY
VSKYTDKQVIPWNGYCISHVRVSTEEIEETRKYYPEAPILVHPECPHEIKETADYIMGTGGMVKFARETEHSTMIIGTEE
GLVHRLKRENPAKNFYLLSPSFFCSNMKKITPQEVLHSLKNLAPEIEVAEETRVKAYQALNNMLRATQ
>Mature_308_residues
MNKFNTSQEEVLKQIRDLKKQVDAIILAHNYQLPQVQKVADFVGDSFELCKTAREVDSSVIIFCGVHFMAEGAKVLAPEK
QVIIPDNNAGCPLADMASPEQVREIKKEFPETPVVAYVNTSAEVKAESHICCTSSNAVDVVNSLDSDSVIFLPDQNLADY
VSKYTDKQVIPWNGYCISHVRVSTEEIEETRKYYPEAPILVHPECPHEIKETADYIMGTGGMVKFARETEHSTMIIGTEE
GLVHRLKRENPAKNFYLLSPSFFCSNMKKITPQEVLHSLKNLAPEIEVAEETRVKAYQALNNMLRATQ

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=311, Percent_Identity=32.7974276527331, Blast_Score=168, Evalue=5e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473
- InterPro:   IPR023066 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 34610; Mature: 34610

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKFNTSQEEVLKQIRDLKKQVDAIILAHNYQLPQVQKVADFVGDSFELCKTAREVDSSV
CCCCCCCHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHCCHHHHHHHHHHHCCCE
IIFCGVHFMAEGAKVLAPEKQVIIPDNNAGCPLADMASPEQVREIKKEFPETPVVAYVNT
EEEECHHHHHCCCEEECCCCEEEECCCCCCCCCHHCCCHHHHHHHHHHCCCCCEEEEECC
SAEVKAESHICCTSSNAVDVVNSLDSDSVIFLPDQNLADYVSKYTDKQVIPWNGYCISHV
CCEEECCCEEEECCCCHHHHHHCCCCCCEEEECCCCHHHHHHHHCCCEECCCCCEEEEEE
RVSTEEIEETRKYYPEAPILVHPECPHEIKETADYIMGTGGMVKFARETEHSTMIIGTEE
EECHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHCCCCCEEEHHCCCCCEEEEECCH
GLVHRLKRENPAKNFYLLSPSFFCSNMKKITPQEVLHSLKNLAPEIEVAEETRVKAYQAL
HHHHHHHCCCCCCCEEEECHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
NNMLRATQ
HHHHHCCC
>Mature Secondary Structure
MNKFNTSQEEVLKQIRDLKKQVDAIILAHNYQLPQVQKVADFVGDSFELCKTAREVDSSV
CCCCCCCHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHCCHHHHHHHHHHHCCCE
IIFCGVHFMAEGAKVLAPEKQVIIPDNNAGCPLADMASPEQVREIKKEFPETPVVAYVNT
EEEECHHHHHCCCEEECCCCEEEECCCCCCCCCHHCCCHHHHHHHHHHCCCCCEEEEECC
SAEVKAESHICCTSSNAVDVVNSLDSDSVIFLPDQNLADYVSKYTDKQVIPWNGYCISHV
CCEEECCCEEEECCCCHHHHHHCCCCCCEEEECCCCHHHHHHHHCCCEECCCCCEEEEEE
RVSTEEIEETRKYYPEAPILVHPECPHEIKETADYIMGTGGMVKFARETEHSTMIIGTEE
EECHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHCCCCCEEEHHCCCCCEEEEECCH
GLVHRLKRENPAKNFYLLSPSFFCSNMKKITPQEVLHSLKNLAPEIEVAEETRVKAYQAL
HHHHHHHCCCCCCCEEEECHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
NNMLRATQ
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA