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The map label for this gene is fliD [H]

Identifier: 188586834

GI number: 188586834

Start: 2363298

End: 2364761

Strand: Reverse

Name: fliD [H]

Synonym: Nther_2225

Alternate gene names: 188586834

Gene position: 2364761-2363298 (Counterclockwise)

Preceding gene: 188586835

Following gene: 188586833

Centisome position: 74.7

GC content: 45.08

Gene sequence:

>1464_bases
ATGAGGCTTGGCGGAATTAGCAGTGGGTTCGATACCCACGGGCTAGTAGAGCGTTTAATGGAAATTGAACGTCAACCCAT
CCAGCGGATGGAAAAGGAAATTGAACAATTGGAATCTACCAAGGAAGAATGGCGTGAGCTCAATAAAACACTTCAGTCCT
TTATGGATGAACTGTCTTCTTTACAGGATAAGGATTTGTATTTTTCCATGGAGGCAGAATCAAGCCATGAGGATATCTCT
GTCACAGCAGAACGAGATGTCATGGCCAGAACCTATGACCTGGAAGTGAGCCAAATCGCCAGGGCCCATAGGATTTCTTC
CGGGCCCATAGAGTCAATCCAAGATCTAGATGATGTAGATGAACCCCTTGAACTTGAAGGAGACCTGGAGCTTTATCTGG
GTGATGAAGAAGAACCCTACACCATCGAAATAGAATCCGAAGACAGCCTGGCAGATATCAGGGATAAAATCAATGACGGT
GATCTAAAAGAAACCGGAGACGAAGAGTTGGATAACAGGGAACTACCCTTAGAAGCCCAGATCATTGGTGATCGGCTAGT
TATAGAGGCAGAACAAACGGGAGAAAGTCACAGCATTACAAAGATCGGTGGTAGTGAAAATGTTTGGGGTCAGGATGGCC
TGAATCTGTGGAATGCGGAAGAAGATTATTTCAGTAATGAAATTGACAAAGCCCAAGATGCCAAGTTCCAAATTAATGGA
TTGGATTTTGAAAATGAATCCAACACCATTGACCATATCATTGATGGTGTCACCATAGATATCGGTGCTATCTCAGCGGA
TCAGGAACTACCGGTCAGTTCCCTGATTTCCATTGAATTGGACGACAACAAGGCCGAAGAAGAGATTTCCGAATTTGTCG
AGAGCTACAATGAAATCTTTAGTAAATTACAAGACAAAGGGCGCATTACTTTAGCAGATGATGAGATCGACAGAGGCCCC
CTACAGGGAGATTCCCTTTTGAGAAATTTGACCAGAAACTTCCGTACAAGGGTGACAGATCCCATTAATGCAGAGGGGTT
AGGACTCAAAAATGATCGCTTGGTTTTGAGTCAATTTGGTATTGAGATCGATCGCTACGGTGAAATGACCTTTGACAAGG
ATAGATTTAAAGAAGCACAGGATGAAAGCGTGAGCCAGGTGTACGAGGCCTTTGGTGGCGAACATGGCATTGGTGCCAGA
TTGCAAAATTATCTGGAAGGGCTTAGCTTTTCCGAAGGGGCCAGGGAAGCTGATATGAGAGAAACAGCCATTGGCAACAG
AAAGCTGACCTTGGATAGACAGATAGATCGCAACGAGGACAGAATGGATCAGATGGAAAGGCGCCTGGAGAGCCGGGAAG
ATCACTTGTGGAGTCAGTTTTCCCGGATGGAACAAGCACTGAACAATGTCTACAGTGAAGGCAACTGGCTGCAGCACCAA
TATATGCACATGTCTTCTCGCTAA

Upstream 100 bases:

>100_bases
CGATTTTATAGAAGATACCGTTTATTATTTATTTAATTCAAATTAATTTAAAATTAAGAAGTTTGATTGACCATTCCAAT
TAACCAGGGAGATGATAATT

Downstream 100 bases:

>100_bases
CAAGGGATGGTACCTTGACTTGTGATAATTATTATCTTGTTAAGTAGTAAAAATTATGGTAAAATTAAGAAAAATTAACA
ATGATTACTATAATCAATTC

Product: flagellar hook-associated 2 domain protein

Products: NA

Alternate protein names: HAP2; Filament cap protein [H]

Number of amino acids: Translated: 487; Mature: 487

Protein sequence:

>487_residues
MRLGGISSGFDTHGLVERLMEIERQPIQRMEKEIEQLESTKEEWRELNKTLQSFMDELSSLQDKDLYFSMEAESSHEDIS
VTAERDVMARTYDLEVSQIARAHRISSGPIESIQDLDDVDEPLELEGDLELYLGDEEEPYTIEIESEDSLADIRDKINDG
DLKETGDEELDNRELPLEAQIIGDRLVIEAEQTGESHSITKIGGSENVWGQDGLNLWNAEEDYFSNEIDKAQDAKFQING
LDFENESNTIDHIIDGVTIDIGAISADQELPVSSLISIELDDNKAEEEISEFVESYNEIFSKLQDKGRITLADDEIDRGP
LQGDSLLRNLTRNFRTRVTDPINAEGLGLKNDRLVLSQFGIEIDRYGEMTFDKDRFKEAQDESVSQVYEAFGGEHGIGAR
LQNYLEGLSFSEGAREADMRETAIGNRKLTLDRQIDRNEDRMDQMERRLESREDHLWSQFSRMEQALNNVYSEGNWLQHQ
YMHMSSR

Sequences:

>Translated_487_residues
MRLGGISSGFDTHGLVERLMEIERQPIQRMEKEIEQLESTKEEWRELNKTLQSFMDELSSLQDKDLYFSMEAESSHEDIS
VTAERDVMARTYDLEVSQIARAHRISSGPIESIQDLDDVDEPLELEGDLELYLGDEEEPYTIEIESEDSLADIRDKINDG
DLKETGDEELDNRELPLEAQIIGDRLVIEAEQTGESHSITKIGGSENVWGQDGLNLWNAEEDYFSNEIDKAQDAKFQING
LDFENESNTIDHIIDGVTIDIGAISADQELPVSSLISIELDDNKAEEEISEFVESYNEIFSKLQDKGRITLADDEIDRGP
LQGDSLLRNLTRNFRTRVTDPINAEGLGLKNDRLVLSQFGIEIDRYGEMTFDKDRFKEAQDESVSQVYEAFGGEHGIGAR
LQNYLEGLSFSEGAREADMRETAIGNRKLTLDRQIDRNEDRMDQMERRLESREDHLWSQFSRMEQALNNVYSEGNWLQHQ
YMHMSSR
>Mature_487_residues
MRLGGISSGFDTHGLVERLMEIERQPIQRMEKEIEQLESTKEEWRELNKTLQSFMDELSSLQDKDLYFSMEAESSHEDIS
VTAERDVMARTYDLEVSQIARAHRISSGPIESIQDLDDVDEPLELEGDLELYLGDEEEPYTIEIESEDSLADIRDKINDG
DLKETGDEELDNRELPLEAQIIGDRLVIEAEQTGESHSITKIGGSENVWGQDGLNLWNAEEDYFSNEIDKAQDAKFQING
LDFENESNTIDHIIDGVTIDIGAISADQELPVSSLISIELDDNKAEEEISEFVESYNEIFSKLQDKGRITLADDEIDRGP
LQGDSLLRNLTRNFRTRVTDPINAEGLGLKNDRLVLSQFGIEIDRYGEMTFDKDRFKEAQDESVSQVYEAFGGEHGIGAR
LQNYLEGLSFSEGAREADMRETAIGNRKLTLDRQIDRNEDRMDQMERRLESREDHLWSQFSRMEQALNNVYSEGNWLQHQ
YMHMSSR

Specific function: Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the

COG id: COG1345

COG function: function code N; Flagellar capping protein

Gene ontology:

Cell location: Secreted. Bacterial flagellum [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fliD family [H]

Homologues:

Organism=Escherichia coli, GI1788233, Length=503, Percent_Identity=22.0675944333996, Blast_Score=92, Evalue=1e-19,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010810
- InterPro:   IPR010809
- InterPro:   IPR003481 [H]

Pfam domain/function: PF07196 Flagellin_IN; PF07195 FliD_C; PF02465 FliD_N [H]

EC number: NA

Molecular weight: Translated: 55804; Mature: 55804

Theoretical pI: Translated: 4.02; Mature: 4.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLGGISSGFDTHGLVERLMEIERQPIQRMEKEIEQLESTKEEWRELNKTLQSFMDELSS
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LQDKDLYFSMEAESSHEDISVTAERDVMARTYDLEVSQIARAHRISSGPIESIQDLDDVD
CCCCCEEEEECCCCCCCCEEEEECHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHCCC
EPLELEGDLELYLGDEEEPYTIEIESEDSLADIRDKINDGDLKETGDEELDNRELPLEAQ
CCCCCCCCEEEEECCCCCCEEEEECCCCCHHHHHHCCCCCCCCCCCCHHCCCCCCCCHHE
IIGDRLVIEAEQTGESHSITKIGGSENVWGQDGLNLWNAEEDYFSNEIDKAQDAKFQING
EECCEEEEEEHHCCCCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCEEEEEC
LDFENESNTIDHIIDGVTIDIGAISADQELPVSSLISIELDDNKAEEEISEFVESYNEIF
CCCCCCCCHHHHHHCCCEEEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHH
SKLQDKGRITLADDEIDRGPLQGDSLLRNLTRNFRTRVTDPINAEGLGLKNDRLVLSQFG
HHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEHHHHC
IEIDRYGEMTFDKDRFKEAQDESVSQVYEAFGGEHGIGARLQNYLEGLSFSEGAREADMR
CCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCHHHHHH
ETAIGNRKLTLDRQIDRNEDRMDQMERRLESREDHLWSQFSRMEQALNNVYSEGNWLQHQ
HHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
YMHMSSR
HHHHCCC
>Mature Secondary Structure
MRLGGISSGFDTHGLVERLMEIERQPIQRMEKEIEQLESTKEEWRELNKTLQSFMDELSS
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LQDKDLYFSMEAESSHEDISVTAERDVMARTYDLEVSQIARAHRISSGPIESIQDLDDVD
CCCCCEEEEECCCCCCCCEEEEECHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHCCC
EPLELEGDLELYLGDEEEPYTIEIESEDSLADIRDKINDGDLKETGDEELDNRELPLEAQ
CCCCCCCCEEEEECCCCCCEEEEECCCCCHHHHHHCCCCCCCCCCCCHHCCCCCCCCHHE
IIGDRLVIEAEQTGESHSITKIGGSENVWGQDGLNLWNAEEDYFSNEIDKAQDAKFQING
EECCEEEEEEHHCCCCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCEEEEEC
LDFENESNTIDHIIDGVTIDIGAISADQELPVSSLISIELDDNKAEEEISEFVESYNEIF
CCCCCCCCHHHHHHCCCEEEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHH
SKLQDKGRITLADDEIDRGPLQGDSLLRNLTRNFRTRVTDPINAEGLGLKNDRLVLSQFG
HHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEHHHHC
IEIDRYGEMTFDKDRFKEAQDESVSQVYEAFGGEHGIGARLQNYLEGLSFSEGAREADMR
CCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCHHHHHH
ETAIGNRKLTLDRQIDRNEDRMDQMERRLESREDHLWSQFSRMEQALNNVYSEGNWLQHQ
HHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
YMHMSSR
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9488388; 10678962 [H]