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The map label for this gene is pyrH [H]

Identifier: 188586055

GI number: 188586055

Start: 1497558

End: 1498274

Strand: Direct

Name: pyrH [H]

Synonym: Nther_1429

Alternate gene names: 188586055

Gene position: 1497558-1498274 (Clockwise)

Preceding gene: 188586054

Following gene: 188586056

Centisome position: 47.31

GC content: 39.89

Gene sequence:

>717_bases
ATGACGACAGATCCCAAAAAACGGGTTGTACTAAAGCTGAGCGGTGAAGCACTTGCCGGTGAAGTAGGTTATGGTATAGA
TACTGATATAATGGATGCAATTTCTCAACAAATTGAAGAAATAGTACAGCTTGGAACTCAAGTTAGTGTTGTAGTAGGTG
GCGGTAATATCTGGAGAGGAGCTGATGCCAGTAAACAAGGCATGGACAGGGCTTCTGCAGACTACATGGGGATGCTAGCT
ACAGTCATGAATGCACTAGCTCTTCAAGATATGCTAGAAAAATATGGAGTAGATACCAGGGTGCAAACCGCTATAGAGAT
GCAGCAAGTTGCCGAACCATATATCAGAAGACGAGCTATAAGGCATTTGGAAAAAGGAAGAGTTGTAATATTTGCTGGAG
GAACGGGCAATCCTTTCTTTTCTACAGATACTACCGCCGCATTAAGAGCTGCTGAAATTGAAGCATCAGTGATTTTACTA
GCGAAAGGAAAAGTTGATGCAGTTTACGATTCTGACCCACTTCAAAACGAAGATGCTCTTAAATTTTCTCATCTTAAATA
TTTGGATGTATTAAATAATAACTTGGGTGTAATGGATTCTACAGCAGCTAGTTTGTGCATGGATAATTCCATACCCATTA
TTGTGTTTGGTCTTTCCCAGAGAGGTAATATAAAAAAGGCAGTCCTGGGAGAAAAAATTGGAACATTAATTGATTAG

Upstream 100 bases:

>100_bases
AGGGAACACCTAGGTGTTCCCTTTTATGAAATTACCATTATTTAAAAGGAATTTTGTAATTATTGTAGAACACAGTCAAA
GGATTAGGGGGTTTAGTTAA

Downstream 100 bases:

>100_bases
GAGGGGATTATGTGGATTCGATTTTTAAAGATGCTGAACAAAAGATGAAAAAAGCTTTGTCTTCTCTTAAAAGTGAGTTG
GCTTCCCTTCGTGCAGGAAG

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 238; Mature: 237

Protein sequence:

>238_residues
MTTDPKKRVVLKLSGEALAGEVGYGIDTDIMDAISQQIEEIVQLGTQVSVVVGGGNIWRGADASKQGMDRASADYMGMLA
TVMNALALQDMLEKYGVDTRVQTAIEMQQVAEPYIRRRAIRHLEKGRVVIFAGGTGNPFFSTDTTAALRAAEIEASVILL
AKGKVDAVYDSDPLQNEDALKFSHLKYLDVLNNNLGVMDSTAASLCMDNSIPIIVFGLSQRGNIKKAVLGEKIGTLID

Sequences:

>Translated_238_residues
MTTDPKKRVVLKLSGEALAGEVGYGIDTDIMDAISQQIEEIVQLGTQVSVVVGGGNIWRGADASKQGMDRASADYMGMLA
TVMNALALQDMLEKYGVDTRVQTAIEMQQVAEPYIRRRAIRHLEKGRVVIFAGGTGNPFFSTDTTAALRAAEIEASVILL
AKGKVDAVYDSDPLQNEDALKFSHLKYLDVLNNNLGVMDSTAASLCMDNSIPIIVFGLSQRGNIKKAVLGEKIGTLID
>Mature_237_residues
TTDPKKRVVLKLSGEALAGEVGYGIDTDIMDAISQQIEEIVQLGTQVSVVVGGGNIWRGADASKQGMDRASADYMGMLAT
VMNALALQDMLEKYGVDTRVQTAIEMQQVAEPYIRRRAIRHLEKGRVVIFAGGTGNPFFSTDTTAALRAAEIEASVILLA
KGKVDAVYDSDPLQNEDALKFSHLKYLDVLNNNLGVMDSTAASLCMDNSIPIIVFGLSQRGNIKKAVLGEKIGTLID

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=240, Percent_Identity=49.1666666666667, Blast_Score=228, Evalue=3e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 25623; Mature: 25492

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTDPKKRVVLKLSGEALAGEVGYGIDTDIMDAISQQIEEIVQLGTQVSVVVGGGNIWRG
CCCCCCCEEEEEECCCEEECCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCEECC
ADASKQGMDRASADYMGMLATVMNALALQDMLEKYGVDTRVQTAIEMQQVAEPYIRRRAI
CCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
RHLEKGRVVIFAGGTGNPFFSTDTTAALRAAEIEASVILLAKGKVDAVYDSDPLQNEDAL
HHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHCCEEEEEEECCCEEEEECCCCCCCCCCH
KFSHLKYLDVLNNNLGVMDSTAASLCMDNSIPIIVFGLSQRGNIKKAVLGEKIGTLID
HHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TTDPKKRVVLKLSGEALAGEVGYGIDTDIMDAISQQIEEIVQLGTQVSVVVGGGNIWRG
CCCCCCEEEEEECCCEEECCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCEECC
ADASKQGMDRASADYMGMLATVMNALALQDMLEKYGVDTRVQTAIEMQQVAEPYIRRRAI
CCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
RHLEKGRVVIFAGGTGNPFFSTDTTAALRAAEIEASVILLAKGKVDAVYDSDPLQNEDAL
HHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHCCEEEEEEECCCEEEEECCCCCCCCCCH
KFSHLKYLDVLNNNLGVMDSTAASLCMDNSIPIIVFGLSQRGNIKKAVLGEKIGTLID
HHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA