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The map label for this gene is frr

Identifier: 188586056

GI number: 188586056

Start: 1498286

End: 1498840

Strand: Direct

Name: frr

Synonym: Nther_1430

Alternate gene names: 188586056

Gene position: 1498286-1498840 (Clockwise)

Preceding gene: 188586055

Following gene: 188586057

Centisome position: 47.33

GC content: 37.84

Gene sequence:

>555_bases
GTGGATTCGATTTTTAAAGATGCTGAACAAAAGATGAAAAAAGCTTTGTCTTCTCTTAAAAGTGAGTTGGCTTCCCTTCG
TGCAGGAAGAGCGAATCCAAGTATTTTAGAAGGGATTAATGTTGATTATTACGGAATGGCCACACCTTTGAATCAGCTAG
CTAATATTTCGGCTCCTGAACCACGTTTGTTAGTAGTGCAACCTTATGACAAAAGTGCTATTGAAGACATTGAAAAAGCA
ATCCTAAAAAGTGATGTCGGCTTGACACCTAACAACGATGGTCAAGTCATTCGACTAGCTGTGCCTCAACTGACGGAAGA
ACGGAGAAATGAGCTAGTGAAAATAGTTAGACAAAAAGGTGAAGATACTAAAGTGGTAGTAAGGAATGTCCGTAGAGATG
CCAATGACGAGCTTAAAAAATTAGAAAAAGAAAAGGAAATTTCCGAGGATGAATCTATCAGAGGACAGGATGAAATTCAA
AAGATAACAGATAAGTACATCAAGAAAATTGACGAAGTAATGAACGCCAAAGAAGAGGAGATCACATCTTTCTAA

Upstream 100 bases:

>100_bases
CCATACCCATTATTGTGTTTGGTCTTTCCCAGAGAGGTAATATAAAAAAGGCAGTCCTGGGAGAAAAAATTGGAACATTA
ATTGATTAGGAGGGGATTAT

Downstream 100 bases:

>100_bases
TGAGTCGAAATTTAACATTAGCTGATTTGAAGTTTGAATTGTTAGGACTGCCTTTGGAAACAGCCAGAGAAAAATTACAG
GAAATGTCTCTATCTTATGA

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MDSIFKDAEQKMKKALSSLKSELASLRAGRANPSILEGINVDYYGMATPLNQLANISAPEPRLLVVQPYDKSAIEDIEKA
ILKSDVGLTPNNDGQVIRLAVPQLTEERRNELVKIVRQKGEDTKVVVRNVRRDANDELKKLEKEKEISEDESIRGQDEIQ
KITDKYIKKIDEVMNAKEEEITSF

Sequences:

>Translated_184_residues
MDSIFKDAEQKMKKALSSLKSELASLRAGRANPSILEGINVDYYGMATPLNQLANISAPEPRLLVVQPYDKSAIEDIEKA
ILKSDVGLTPNNDGQVIRLAVPQLTEERRNELVKIVRQKGEDTKVVVRNVRRDANDELKKLEKEKEISEDESIRGQDEIQ
KITDKYIKKIDEVMNAKEEEITSF
>Mature_184_residues
MDSIFKDAEQKMKKALSSLKSELASLRAGRANPSILEGINVDYYGMATPLNQLANISAPEPRLLVVQPYDKSAIEDIEKA
ILKSDVGLTPNNDGQVIRLAVPQLTEERRNELVKIVRQKGEDTKVVVRNVRRDANDELKKLEKEKEISEDESIRGQDEIQ
KITDKYIKKIDEVMNAKEEEITSF

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=180, Percent_Identity=28.3333333333333, Blast_Score=67, Evalue=9e-12,
Organism=Escherichia coli, GI1786368, Length=181, Percent_Identity=50.828729281768, Blast_Score=186, Evalue=8e-49,
Organism=Drosophila melanogaster, GI24661488, Length=178, Percent_Identity=25.2808988764045, Blast_Score=74, Evalue=5e-14,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_NATTJ (B2A383)

Other databases:

- EMBL:   CP001034
- RefSeq:   YP_001917601.1
- ProteinModelPortal:   B2A383
- SMR:   B2A383
- GeneID:   6314559
- GenomeReviews:   CP001034_GR
- KEGG:   nth:Nther_1430
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20825; Mature: 20825

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSIFKDAEQKMKKALSSLKSELASLRAGRANPSILEGINVDYYGMATPLNQLANISAPE
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCHHHHHHHHCCCCCC
PRLLVVQPYDKSAIEDIEKAILKSDVGLTPNNDGQVIRLAVPQLTEERRNELVKIVRQKG
CCEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHCC
EDTKVVVRNVRRDANDELKKLEKEKEISEDESIRGQDEIQKITDKYIKKIDEVMNAKEEE
CCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHH
ITSF
HCCC
>Mature Secondary Structure
MDSIFKDAEQKMKKALSSLKSELASLRAGRANPSILEGINVDYYGMATPLNQLANISAPE
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCHHHHHHHHCCCCCC
PRLLVVQPYDKSAIEDIEKAILKSDVGLTPNNDGQVIRLAVPQLTEERRNELVKIVRQKG
CCEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHCC
EDTKVVVRNVRRDANDELKKLEKEKEISEDESIRGQDEIQKITDKYIKKIDEVMNAKEEE
CCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHH
ITSF
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA