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The map label for this gene is tsf [H]

Identifier: 188586054

GI number: 188586054

Start: 1496799

End: 1497449

Strand: Direct

Name: tsf [H]

Synonym: Nther_1428

Alternate gene names: 188586054

Gene position: 1496799-1497449 (Clockwise)

Preceding gene: 188586053

Following gene: 188586055

Centisome position: 47.28

GC content: 37.63

Gene sequence:

>651_bases
ATGGTCAAAGCTGCACAAGTAAAGGAGTTAAGAGAGAAATCAGGTGCTGGAATGATGGATTGTAAAAAGGCTCTCAAAGA
AAGTGACGGAGACATGGATAAGGCCATGGAGTATCTTAAGGAAAAAGGCCTAGCTAGTGCTAAGAAAAAAGCAGATCGAA
CCACTACTGAAGGAAGAGTTGAATCATATATTCACCTAGGTGGCAAAATCGGCGTTTTAATAGAGGTTAATTGTGAAACT
GACTTTGTTGCCAGTAATGATGAATTTAAGCAATTCACAAAAGATATCGCAATGCAAGTGGCTGCATCAGCCCCTCAATA
CATATCTAGGGATGAAGTACCACAGGAGGAAGTGGAAAAAGAAAGAGAAAGATTGAAGCAGCAAGCTATTGATGAAGGAA
AGCCTGAGCATGTAGTCGATCAGATCGTTGATGGAAAGATGGACAAATATTACGAAGAAATTTGCTTATTAGACCAACCT
TTTGTGAAAGATCCAGATAAAAGCGTTGATGAACTGAAAAAAGAAAAGATAGCCAAAATTGGCGAAAACATTAGTGTGAG
ACGATTTGTCAGATACGAATTAGGTGAAGGTAAAGAAAAGAAAGAAGAAAATTTTGCAGAAGAAGTTGAAGCAATTAAGC
AAAATACTTAA

Upstream 100 bases:

>100_bases
GGGGTAGGGGCTCGATAAGTATAATATTATACTTATCGAACTTACCCCAAATTTATGGAATAAATAAACAAAATTGTGGG
ATGTAAGGAGGATGAAAAGT

Downstream 100 bases:

>100_bases
GCTTGTCAAGGGAACACCTAGGTGTTCCCTTTTATGAAATTACCATTATTTAAAAGGAATTTTGTAATTATTGTAGAACA
CAGTCAAAGGATTAGGGGGT

Product: translation elongation factor Ts (EF-Ts)

Products: NA

Alternate protein names: EF-Ts [H]

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MVKAAQVKELREKSGAGMMDCKKALKESDGDMDKAMEYLKEKGLASAKKKADRTTTEGRVESYIHLGGKIGVLIEVNCET
DFVASNDEFKQFTKDIAMQVAASAPQYISRDEVPQEEVEKERERLKQQAIDEGKPEHVVDQIVDGKMDKYYEEICLLDQP
FVKDPDKSVDELKKEKIAKIGENISVRRFVRYELGEGKEKKEENFAEEVEAIKQNT

Sequences:

>Translated_216_residues
MVKAAQVKELREKSGAGMMDCKKALKESDGDMDKAMEYLKEKGLASAKKKADRTTTEGRVESYIHLGGKIGVLIEVNCET
DFVASNDEFKQFTKDIAMQVAASAPQYISRDEVPQEEVEKERERLKQQAIDEGKPEHVVDQIVDGKMDKYYEEICLLDQP
FVKDPDKSVDELKKEKIAKIGENISVRRFVRYELGEGKEKKEENFAEEVEAIKQNT
>Mature_216_residues
MVKAAQVKELREKSGAGMMDCKKALKESDGDMDKAMEYLKEKGLASAKKKADRTTTEGRVESYIHLGGKIGVLIEVNCET
DFVASNDEFKQFTKDIAMQVAASAPQYISRDEVPQEEVEKERERLKQQAIDEGKPEHVVDQIVDGKMDKYYEEICLLDQP
FVKDPDKSVDELKKEKIAKIGENISVRRFVRYELGEGKEKKEENFAEEVEAIKQNT

Specific function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome [H]

COG id: COG0264

COG function: function code J; Translation elongation factor Ts

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-Ts family [H]

Homologues:

Organism=Escherichia coli, GI1786366, Length=155, Percent_Identity=40, Blast_Score=104, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17561440, Length=195, Percent_Identity=29.7435897435897, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI19921466, Length=97, Percent_Identity=40.2061855670103, Blast_Score=74, Evalue=9e-14,

Paralogues:

None

Copy number: 2670 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1100 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 4173 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 14563 Molecules/Cell In: Growth Phase, Gluco

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001816
- InterPro:   IPR014039
- InterPro:   IPR018101
- InterPro:   IPR009060
- InterPro:   IPR000449 [H]

Pfam domain/function: PF00889 EF_TS; PF00627 UBA [H]

EC number: NA

Molecular weight: Translated: 24558; Mature: 24558

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS01126 EF_TS_1 ; PS01127 EF_TS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKAAQVKELREKSGAGMMDCKKALKESDGDMDKAMEYLKEKGLASAKKKADRTTTEGRV
CCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHCCCHHHHH
ESYIHLGGKIGVLIEVNCETDFVASNDEFKQFTKDIAMQVAASAPQYISRDEVPQEEVEK
HHHHHCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHCCCCCCHHHHHH
ERERLKQQAIDEGKPEHVVDQIVDGKMDKYYEEICLLDQPFVKDPDKSVDELKKEKIAKI
HHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
GENISVRRFVRYELGEGKEKKEENFAEEVEAIKQNT
CCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVKAAQVKELREKSGAGMMDCKKALKESDGDMDKAMEYLKEKGLASAKKKADRTTTEGRV
CCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHCCCHHHHH
ESYIHLGGKIGVLIEVNCETDFVASNDEFKQFTKDIAMQVAASAPQYISRDEVPQEEVEK
HHHHHCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHCCCCCCHHHHHH
ERERLKQQAIDEGKPEHVVDQIVDGKMDKYYEEICLLDQPFVKDPDKSVDELKKEKIAKI
HHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
GENISVRRFVRYELGEGKEKKEENFAEEVEAIKQNT
CCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA