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The map label for this gene is yfiK [H]

Identifier: 188585380

GI number: 188585380

Start: 775879

End: 776577

Strand: Reverse

Name: yfiK [H]

Synonym: Nther_0747

Alternate gene names: 188585380

Gene position: 776577-775879 (Counterclockwise)

Preceding gene: 188585381

Following gene: 188585379

Centisome position: 24.53

GC content: 35.77

Gene sequence:

>699_bases
ATGAGTAAAATTAAAGTGATGATAGCAGATGACCAAACTATTCTTGCCGATAGCTTAAAAACAATTATAGACCTAGAAGA
TGATATGGAGGTTGTGGCGGTTTCTAGTAATGGTGAAGAAACCCTAGAAATCAGTGAAAAGCTACTTCCCGATATTATAC
TGATGGATATCAGGATGCCTAAAATGGATGGTGTTGAATGCACTAAAAAACTTAAAGAGAAGTATCCAGAAATTAAAATA
ATTATCCTGACAACCTTTGATCATGATGAATATATCGTTGATGCCCTTTCCTATGGTGCAAGTGGTTATTTATTAAAAGA
TATAGACGGAGATAAGCTTATCAGTTCTATACGAGATGCTTATAATGATAAGTTATTAATACCCACTTCTATTGCAGCCA
AACTCATTGGGAAAATAGATAATAGGAAGCAACAACCAACTGATGACCATAAAGATGAGCCGTTAAAAAGTCAAGATCGT
AAGGAAAGTCAGAAAGAGATTAATCTATACGAGGAACTGACCCAACGGGAAATAGAAATTGCCCAATTAATGGTAGCAGG
TCTTTCAAACAAGAAGATCGCCGAAAAATTGTTCATCACCCAGGGGACAGTCAAAAATTATATCACCAATATTTACAGCA
AACTGGGGGTCAAGGAAAGAACAAGTGCAGTGCTTTATCTTCAAAAGTTAGGGTTTTAG

Upstream 100 bases:

>100_bases
ACAGAGTAGAAGAATTAGGAGGCAGCCTTACAGCGAATTCCAAACAAGATGGTGGTTTTATACTGTCTATTGAAATCCCG
GTAGAAGAAGGTGAGGAATT

Downstream 100 bases:

>100_bases
CTCAATGTCGATTATGGAAAATCTACTATAATAAAATATGACCGATCATATGACTCGGGTCACTAATCATATTACCTCCC
CTCTTATTATAATTGACTTA

Product: two component transcriptional regulator, LuxR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MSKIKVMIADDQTILADSLKTIIDLEDDMEVVAVSSNGEETLEISEKLLPDIILMDIRMPKMDGVECTKKLKEKYPEIKI
IILTTFDHDEYIVDALSYGASGYLLKDIDGDKLISSIRDAYNDKLLIPTSIAAKLIGKIDNRKQQPTDDHKDEPLKSQDR
KESQKEINLYEELTQREIEIAQLMVAGLSNKKIAEKLFITQGTVKNYITNIYSKLGVKERTSAVLYLQKLGF

Sequences:

>Translated_232_residues
MSKIKVMIADDQTILADSLKTIIDLEDDMEVVAVSSNGEETLEISEKLLPDIILMDIRMPKMDGVECTKKLKEKYPEIKI
IILTTFDHDEYIVDALSYGASGYLLKDIDGDKLISSIRDAYNDKLLIPTSIAAKLIGKIDNRKQQPTDDHKDEPLKSQDR
KESQKEINLYEELTQREIEIAQLMVAGLSNKKIAEKLFITQGTVKNYITNIYSKLGVKERTSAVLYLQKLGF
>Mature_231_residues
SKIKVMIADDQTILADSLKTIIDLEDDMEVVAVSSNGEETLEISEKLLPDIILMDIRMPKMDGVECTKKLKEKYPEIKII
ILTTFDHDEYIVDALSYGASGYLLKDIDGDKLISSIRDAYNDKLLIPTSIAAKLIGKIDNRKQQPTDDHKDEPLKSQDRK
ESQKEINLYEELTQREIEIAQLMVAGLSNKKIAEKLFITQGTVKNYITNIYSKLGVKERTSAVLYLQKLGF

Specific function: Member of the two-component regulatory system yfiJ/yfiK [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1787473, Length=224, Percent_Identity=31.25, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI1788521, Length=231, Percent_Identity=29.4372294372294, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1788222, Length=214, Percent_Identity=25.2336448598131, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1790102, Length=214, Percent_Identity=26.6355140186916, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788712, Length=229, Percent_Identity=24.0174672489083, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI87082052, Length=112, Percent_Identity=37.5, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1788550, Length=109, Percent_Identity=33.0275229357798, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1790437, Length=89, Percent_Identity=35.9550561797753, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI1790299, Length=84, Percent_Identity=38.0952380952381, Blast_Score=64, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 26288; Mature: 26157

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKIKVMIADDQTILADSLKTIIDLEDDMEVVAVSSNGEETLEISEKLLPDIILMDIRMP
CCCEEEEEECCCHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHCCHHEEEECCCC
KMDGVECTKKLKEKYPEIKIIILTTFDHDEYIVDALSYGASGYLLKDIDGDKLISSIRDA
CCCCHHHHHHHHHHCCCEEEEEEEEECCCHHHHHHHHCCCCCCEEECCCHHHHHHHHHHH
YNDKLLIPTSIAAKLIGKIDNRKQQPTDDHKDEPLKSQDRKESQKEINLYEELTQREIEI
HCCCEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AQLMVAGLSNKKIAEKLFITQGTVKNYITNIYSKLGVKERTSAVLYLQKLGF
HHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SKIKVMIADDQTILADSLKTIIDLEDDMEVVAVSSNGEETLEISEKLLPDIILMDIRMP
CCEEEEEECCCHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHCCHHEEEECCCC
KMDGVECTKKLKEKYPEIKIIILTTFDHDEYIVDALSYGASGYLLKDIDGDKLISSIRDA
CCCCHHHHHHHHHHCCCEEEEEEEEECCCHHHHHHHHCCCCCCEEECCCHHHHHHHHHHH
YNDKLLIPTSIAAKLIGKIDNRKQQPTDDHKDEPLKSQDRKESQKEINLYEELTQREIEI
HCCCEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AQLMVAGLSNKKIAEKLFITQGTVKNYITNIYSKLGVKERTSAVLYLQKLGF
HHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8973323; 9384377 [H]