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The map label for this gene is yxjM [H]

Identifier: 188585381

GI number: 188585381

Start: 776574

End: 777755

Strand: Reverse

Name: yxjM [H]

Synonym: Nther_0748

Alternate gene names: 188585381

Gene position: 777755-776574 (Counterclockwise)

Preceding gene: 188585390

Following gene: 188585380

Centisome position: 24.57

GC content: 32.57

Gene sequence:

>1182_bases
TTGGATCAGAGAACTAAAAATATTTCTGATATTTTAACTTTGATAGGTTTCCTATTTGCTTTTTTAGGTACTATTACTCA
AAGCCCAGAACATCAAATAGAAATTTTGATACTATCATTTTTGTTAGCGAGTTCATTTCTGGCACGAAGCTATACCGTAT
CTGACAAAATTCAGGTTATTCATAGATATGAAGTCCCCTTAATCATTTTTGAAATTATGATTGTTACGATAATTATGTAT
TTTGACCAGTCAGGTGCTTCACAAATATATTATTTCATCCTGATAGCTGATGCTGTGTTGTATTTTTCTATAAAGTTTGC
TTTAAGCCTTACTTTGCTAATTTTTTTGGCTTTTATGATAAATGCTTGGATAGCCCTCTGGCCTGAAATGACTTTAAATG
ACATTTTAGTAATCGGTTTATTAAATGGTATTGGATATATTTTTGTTTTTTTAATTACTTATTTAGTCAAACATCAAGTT
AATCAAAGGAATTTTATTAATGAAACCTTGAAAGAATTAGAGTATAAAAATAAGAAACTGGAAGAAAGCCAAAAACAGTT
AGAAAATATGGCAGTTATCAAAGAAAGAAATAGAATTGCCCATGATATCCATGACACCGTCGGTCACACCCTGACAACGG
TACTAGTTGGAACTGAAGCCGCAAAGCGCTTAATAGATAAAGATCCGGAATTAGCTAAGGAAAAGCTGTCACTAGCCCAG
GATCAAGTGAGAAAAGGATTGAATAATATTAAAAATTCCATAAAAGATATTAAAGATCATAATGAAATCATTGATTTTAA
TAGTGCAGTTAATAATCTTATCCATGAGACCGAGCAACAAACAGACATAGAGATTGATTGCCATATTTCTGTCTCAGAAG
ATCAAATCAGTCAAACTAAACAAAAGGTAATTTTGAGGGCACTACAGGAAGGGTTAACAAATGGGATTAAACACGGGAAC
AGCACATATTTCAAATTCAATCTAATAGAAGATCAGGAATATATTTATTTTGACCTAGAAGATAACGGTACGGGAAGTGA
AGATAAAGATATGGGCTTTGGCCTCAATTTTATGAAAGACAGAGTAGAAGAATTAGGAGGCAGCCTTACAGCGAATTCCA
AACAAGATGGTGGTTTTATACTGTCTATTGAAATCCCGGTAGAAGAAGGTGAGGAATTATGA

Upstream 100 bases:

>100_bases
CTCTAGTCATTATTATTTTTTACTATAAGGTATAACTTTACATTCTAAAAAAGGATATCAATTAATACTAGGCGAATTAA
CTATTAGAGGAGTGGTGAAT

Downstream 100 bases:

>100_bases
GTAAAATTAAAGTGATGATAGCAGATGACCAAACTATTCTTGCCGATAGCTTAAAAACAATTATAGACCTAGAAGATGAT
ATGGAGGTTGTGGCGGTTTC

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MDQRTKNISDILTLIGFLFAFLGTITQSPEHQIEILILSFLLASSFLARSYTVSDKIQVIHRYEVPLIIFEIMIVTIIMY
FDQSGASQIYYFILIADAVLYFSIKFALSLTLLIFLAFMINAWIALWPEMTLNDILVIGLLNGIGYIFVFLITYLVKHQV
NQRNFINETLKELEYKNKKLEESQKQLENMAVIKERNRIAHDIHDTVGHTLTTVLVGTEAAKRLIDKDPELAKEKLSLAQ
DQVRKGLNNIKNSIKDIKDHNEIIDFNSAVNNLIHETEQQTDIEIDCHISVSEDQISQTKQKVILRALQEGLTNGIKHGN
STYFKFNLIEDQEYIYFDLEDNGTGSEDKDMGFGLNFMKDRVEELGGSLTANSKQDGGFILSIEIPVEEGEEL

Sequences:

>Translated_393_residues
MDQRTKNISDILTLIGFLFAFLGTITQSPEHQIEILILSFLLASSFLARSYTVSDKIQVIHRYEVPLIIFEIMIVTIIMY
FDQSGASQIYYFILIADAVLYFSIKFALSLTLLIFLAFMINAWIALWPEMTLNDILVIGLLNGIGYIFVFLITYLVKHQV
NQRNFINETLKELEYKNKKLEESQKQLENMAVIKERNRIAHDIHDTVGHTLTTVLVGTEAAKRLIDKDPELAKEKLSLAQ
DQVRKGLNNIKNSIKDIKDHNEIIDFNSAVNNLIHETEQQTDIEIDCHISVSEDQISQTKQKVILRALQEGLTNGIKHGN
STYFKFNLIEDQEYIYFDLEDNGTGSEDKDMGFGLNFMKDRVEELGGSLTANSKQDGGFILSIEIPVEEGEEL
>Mature_393_residues
MDQRTKNISDILTLIGFLFAFLGTITQSPEHQIEILILSFLLASSFLARSYTVSDKIQVIHRYEVPLIIFEIMIVTIIMY
FDQSGASQIYYFILIADAVLYFSIKFALSLTLLIFLAFMINAWIALWPEMTLNDILVIGLLNGIGYIFVFLITYLVKHQV
NQRNFINETLKELEYKNKKLEESQKQLENMAVIKERNRIAHDIHDTVGHTLTTVLVGTEAAKRLIDKDPELAKEKLSLAQ
DQVRKGLNNIKNSIKDIKDHNEIIDFNSAVNNLIHETEQQTDIEIDCHISVSEDQISQTKQKVILRALQEGLTNGIKHGN
STYFKFNLIEDQEYIYFDLEDNGTGSEDKDMGFGLNFMKDRVEELGGSLTANSKQDGGFILSIEIPVEEGEEL

Specific function: Probable member of the two-component regulatory system yxjM/yxjL. May activate yxjL by phosphorylation [H]

COG id: COG4585

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788812, Length=225, Percent_Identity=25.3333333333333, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI87082311, Length=230, Percent_Identity=25.2173913043478, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011712 [H]

Pfam domain/function: PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 44853; Mature: 44853

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQRTKNISDILTLIGFLFAFLGTITQSPEHQIEILILSFLLASSFLARSYTVSDKIQVI
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
HRYEVPLIIFEIMIVTIIMYFDQSGASQIYYFILIADAVLYFSIKFALSLTLLIFLAFMI
HHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NAWIALWPEMTLNDILVIGLLNGIGYIFVFLITYLVKHQVNQRNFINETLKELEYKNKKL
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
EESQKQLENMAVIKERNRIAHDIHDTVGHTLTTVLVGTEAAKRLIDKDPELAKEKLSLAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
DQVRKGLNNIKNSIKDIKDHNEIIDFNSAVNNLIHETEQQTDIEIDCHISVSEDQISQTK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHH
QKVILRALQEGLTNGIKHGNSTYFKFNLIEDQEYIYFDLEDNGTGSEDKDMGFGLNFMKD
HHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCEEEEEEECCCCCCCCCCCCCCCHHHHHH
RVEELGGSLTANSKQDGGFILSIEIPVEEGEEL
HHHHHCCCCCCCCCCCCCEEEEEEEECCCCCCC
>Mature Secondary Structure
MDQRTKNISDILTLIGFLFAFLGTITQSPEHQIEILILSFLLASSFLARSYTVSDKIQVI
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
HRYEVPLIIFEIMIVTIIMYFDQSGASQIYYFILIADAVLYFSIKFALSLTLLIFLAFMI
HHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NAWIALWPEMTLNDILVIGLLNGIGYIFVFLITYLVKHQVNQRNFINETLKELEYKNKKL
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
EESQKQLENMAVIKERNRIAHDIHDTVGHTLTTVLVGTEAAKRLIDKDPELAKEKLSLAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
DQVRKGLNNIKNSIKDIKDHNEIIDFNSAVNNLIHETEQQTDIEIDCHISVSEDQISQTK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHH
QKVILRALQEGLTNGIKHGNSTYFKFNLIEDQEYIYFDLEDNGTGSEDKDMGFGLNFMKD
HHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCEEEEEEECCCCCCCCCCCCCCCHHHHHH
RVEELGGSLTANSKQDGGFILSIEIPVEEGEEL
HHHHHCCCCCCCCCCCCCEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8978088; 8969509; 9384377 [H]