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The map label for this gene is capA [H]

Identifier: 188585359

GI number: 188585359

Start: 750390

End: 751742

Strand: Reverse

Name: capA [H]

Synonym: Nther_0726

Alternate gene names: 188585359

Gene position: 751742-750390 (Counterclockwise)

Preceding gene: 188585363

Following gene: 188585356

Centisome position: 23.75

GC content: 38.06

Gene sequence:

>1353_bases
ATGTTTATCAAATACAAAGCTACCGACAATTTAAGTGTGACACTTCTTTCAAATATGTTAATTTGTTTGTTACTACTATC
AACAACTTTTTTATCAGCATGTAACCAAAATGAGGATCAAAACAGTAAATCCGAGACCATGAAAGAAGAAGAACAAAAAG
AAGAAAAGGAAGCTAAAGAGGGCAAAGCCCAAGAAACAGAAACCGAACAGCAAAATTTAGAAGAAACCAATGAAATTGTA
ATTTCTGCCGTTGGAGATGTTATGGTCCACGGTCCCCAGTTAGAAGCCCAGTACGACAGTGAGAAAAACGAATACGATTT
TAATGATAATTTTGAGTACATAAAACCTTATATTGACCAGGCAGACCTGGCTCTAGCTAATTTGGAAACTGTTCTGGCGG
GAGGAGAACGAGGTTATAGTGGTTATCCCATGTTCAATAGTCCCGATGTCTTGGCAGATGCTTTGAAAAATTCAGGTTTT
AATGTTTTATCAACGGCTAATAACCACAGCCTTGATCAGGGAGAAGCTGGCCTAAGAAGAACAGTAGAAGTTTTAGAAGA
TAGAGGATTAAAGGCAATCGGCACAAAAAAACAAGCAGAGGATGACAGTTATTTGATCAAAGAAATTGAAGGAATCAAGA
TAGGGTTATCAGCTTTTACATATGAAACCCCTCGAATTGACGGGCAACGAACTATTAATGGCATCCCTATGTCTGATAAG
ACAGCCGAACTAATCGATAGTTTCAATTATGATGAATTAAATCAAGATATGGAAGATTTGACAGAAAGGGCTGAACATTT
ACAAGATCAGGGAGCAGATGTCATAGCTTTTTTCATGCACTGGGGAACGGAGTACGAAAGACAGCCCAATGAATATCAAG
AAAAAATAGCAGAAGAACTGGTGGACAGTGGAGTAGATATAATCTTTGGGAGTCATCCCCATGTAGTTCAGCCAGTCGAG
GAAATTAAAACACCTTCAGGAGAAGAAGGAATTGTGATTTATTCCATGGGAAATTTTCTTTCAAATCAAAGAAGGGAATA
TCTGGACCGGCCTTATACCGAAGACGGTGTGATTATGCATGTCACTATTGAAAAAGACGCCCATGCAGACATTGAAATAA
CTGAAACAGCTTATACGCCTACATGGGTACATAAATACCGTGAAAATGAAGAGAGGAACTACGAGATTGTACCTCTTCCC
GATGCCTTAGAACATGAAAAAATTTACAACTTACATACAGAAGAAAGCGTTAACAGAGCACAACAATCATTAGAAAATAC
CAATAAGATATTGACAACTGATGATTCTTTTACACCCGAACACATTCATTCACTGTTCCCTCCACAGGACTAA

Upstream 100 bases:

>100_bases
TGCAGGAATATTTTACTGAAAAAGCCAATTTAATATTTTAATAGCTATTGGAAAAAGAAAGGAACAAATCACAGATTTCT
AGTGAAAGGAGAACCAGATT

Downstream 100 bases:

>100_bases
GGGTTTAAAACAACTTTAATACAATCATCCATATTCAGGATAGAATTAAACAGCTGTCCATCCACCATCAACAAAAATTG
TTTGACCATTGACATAACTT

Product: CapA domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MFIKYKATDNLSVTLLSNMLICLLLLSTTFLSACNQNEDQNSKSETMKEEEQKEEKEAKEGKAQETETEQQNLEETNEIV
ISAVGDVMVHGPQLEAQYDSEKNEYDFNDNFEYIKPYIDQADLALANLETVLAGGERGYSGYPMFNSPDVLADALKNSGF
NVLSTANNHSLDQGEAGLRRTVEVLEDRGLKAIGTKKQAEDDSYLIKEIEGIKIGLSAFTYETPRIDGQRTINGIPMSDK
TAELIDSFNYDELNQDMEDLTERAEHLQDQGADVIAFFMHWGTEYERQPNEYQEKIAEELVDSGVDIIFGSHPHVVQPVE
EIKTPSGEEGIVIYSMGNFLSNQRREYLDRPYTEDGVIMHVTIEKDAHADIEITETAYTPTWVHKYRENEERNYEIVPLP
DALEHEKIYNLHTEESVNRAQQSLENTNKILTTDDSFTPEHIHSLFPPQD

Sequences:

>Translated_450_residues
MFIKYKATDNLSVTLLSNMLICLLLLSTTFLSACNQNEDQNSKSETMKEEEQKEEKEAKEGKAQETETEQQNLEETNEIV
ISAVGDVMVHGPQLEAQYDSEKNEYDFNDNFEYIKPYIDQADLALANLETVLAGGERGYSGYPMFNSPDVLADALKNSGF
NVLSTANNHSLDQGEAGLRRTVEVLEDRGLKAIGTKKQAEDDSYLIKEIEGIKIGLSAFTYETPRIDGQRTINGIPMSDK
TAELIDSFNYDELNQDMEDLTERAEHLQDQGADVIAFFMHWGTEYERQPNEYQEKIAEELVDSGVDIIFGSHPHVVQPVE
EIKTPSGEEGIVIYSMGNFLSNQRREYLDRPYTEDGVIMHVTIEKDAHADIEITETAYTPTWVHKYRENEERNYEIVPLP
DALEHEKIYNLHTEESVNRAQQSLENTNKILTTDDSFTPEHIHSLFPPQD
>Mature_450_residues
MFIKYKATDNLSVTLLSNMLICLLLLSTTFLSACNQNEDQNSKSETMKEEEQKEEKEAKEGKAQETETEQQNLEETNEIV
ISAVGDVMVHGPQLEAQYDSEKNEYDFNDNFEYIKPYIDQADLALANLETVLAGGERGYSGYPMFNSPDVLADALKNSGF
NVLSTANNHSLDQGEAGLRRTVEVLEDRGLKAIGTKKQAEDDSYLIKEIEGIKIGLSAFTYETPRIDGQRTINGIPMSDK
TAELIDSFNYDELNQDMEDLTERAEHLQDQGADVIAFFMHWGTEYERQPNEYQEKIAEELVDSGVDIIFGSHPHVVQPVE
EIKTPSGEEGIVIYSMGNFLSNQRREYLDRPYTEDGVIMHVTIEKDAHADIEITETAYTPTWVHKYRENEERNYEIVPLP
DALEHEKIYNLHTEESVNRAQQSLENTNKILTTDDSFTPEHIHSLFPPQD

Specific function: Essential for the synthesis of the polyglutamate capsule of B.anthracis which is one of the principal virulence factors during anthrax infection. May form a polyglutamyl synthetase complex together with proteins CapB and CapC [H]

COG id: COG2843

COG function: function code M; Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CapA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019079 [H]

Pfam domain/function: PF09587 PGA_cap [H]

EC number: NA

Molecular weight: Translated: 51172; Mature: 51172

Theoretical pI: Translated: 4.13; Mature: 4.13

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFIKYKATDNLSVTLLSNMLICLLLLSTTFLSACNQNEDQNSKSETMKEEEQKEEKEAKE
CEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
GKAQETETEQQNLEETNEIVISAVGDVMVHGPQLEAQYDSEKNEYDFNDNFEYIKPYIDQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCHHHHHHHHCH
ADLALANLETVLAGGERGYSGYPMFNSPDVLADALKNSGFNVLSTANNHSLDQGEAGLRR
HHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHH
TVEVLEDRGLKAIGTKKQAEDDSYLIKEIEGIKIGLSAFTYETPRIDGQRTINGIPMSDK
HHHHHHHCCCEECCCCCCCCCHHHHHHHHCCCEEEHHHEEECCCCCCCCCCCCCCCCCCH
TAELIDSFNYDELNQDMEDLTERAEHLQDQGADVIAFFMHWGTEYERQPNEYQEKIAEEL
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHH
VDSGVDIIFGSHPHVVQPVEEIKTPSGEEGIVIYSMGNFLSNQRREYLDRPYTEDGVIMH
HHCCCEEEECCCCCCCCCHHHHCCCCCCCCEEEEECCHHHHHHHHHHHCCCCCCCCEEEE
VTIEKDAHADIEITETAYTPTWVHKYRENEERNYEIVPLPDALEHEKIYNLHTEESVNRA
EEECCCCCCCEEEEECCCCHHHHHHHHCCCCCCEEEEECCCCCCHHHHHCCCCHHHHHHH
QQSLENTNKILTTDDSFTPEHIHSLFPPQD
HHHHHHCCCEEECCCCCCHHHHHHCCCCCC
>Mature Secondary Structure
MFIKYKATDNLSVTLLSNMLICLLLLSTTFLSACNQNEDQNSKSETMKEEEQKEEKEAKE
CEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
GKAQETETEQQNLEETNEIVISAVGDVMVHGPQLEAQYDSEKNEYDFNDNFEYIKPYIDQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCHHHHHHHHCH
ADLALANLETVLAGGERGYSGYPMFNSPDVLADALKNSGFNVLSTANNHSLDQGEAGLRR
HHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHH
TVEVLEDRGLKAIGTKKQAEDDSYLIKEIEGIKIGLSAFTYETPRIDGQRTINGIPMSDK
HHHHHHHCCCEECCCCCCCCCHHHHHHHHCCCEEEHHHEEECCCCCCCCCCCCCCCCCCH
TAELIDSFNYDELNQDMEDLTERAEHLQDQGADVIAFFMHWGTEYERQPNEYQEKIAEEL
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHH
VDSGVDIIFGSHPHVVQPVEEIKTPSGEEGIVIYSMGNFLSNQRREYLDRPYTEDGVIMH
HHCCCEEEECCCCCCCCCHHHHCCCCCCCCEEEEECCHHHHHHHHHHHCCCCCCCCEEEE
VTIEKDAHADIEITETAYTPTWVHKYRENEERNYEIVPLPDALEHEKIYNLHTEESVNRA
EEECCCCCCCEEEEECCCCHHHHHHHHCCCCCCEEEEECCCCCCHHHHHCCCCHHHHHHH
QQSLENTNKILTTDDSFTPEHIHSLFPPQD
HHHHHHCCCEEECCCCCCHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2536679; 10475962; 12004073 [H]