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The map label for this gene is groS

Identifier: 188585088

GI number: 188585088

Start: 473384

End: 473671

Strand: Direct

Name: groS

Synonym: Nther_0449

Alternate gene names: 188585088

Gene position: 473384-473671 (Clockwise)

Preceding gene: 188585087

Following gene: 188585089

Centisome position: 14.95

GC content: 41.67

Gene sequence:

>288_bases
ATGAACTTAAAACCGCTGGGAGATCGTATTGTAATTAAAATCTTGGAAGCCGAAGAAAAAACAGAAAGTGGAATCGTACT
TCCCGAAAAGGCTAAAGAAAAGCCCCAAGAAGGCGAAGTAGTTGCGGTTGGAAGCGGTAAAACGCTGGATGATGGAAGCA
AAGTGGAACCCGAAGTAAAAGCAGGCGATAAAGTGGTTTATTCCAAATTCGCTGGAAATGAAGTTGAGGTTGATGGTGAA
GAATACTTAATCATGCGCCAGGATGATATCTTGGCGGTTATAGAATAA

Upstream 100 bases:

>100_bases
CTACATCTATTAATATAATAAATGTGATTAGCACTCGACATTAGTGAGTGCTAATAAAATGTTTGATATACATAAATACA
ACATAAAAGGAGGGTTCAAG

Downstream 100 bases:

>100_bases
AACCCACATAAAGGAGGTAATGTGCTATGGCAAAGGACATTAAATTTAGAGAAGATGCTCGTGCCAGATTAGAGCAAGGT
GTAAATAAGTTAGCTGACAC

Product: chaperonin Cpn10

Products: NA

Alternate protein names: GroES protein; Protein Cpn10

Number of amino acids: Translated: 95; Mature: 95

Protein sequence:

>95_residues
MNLKPLGDRIVIKILEAEEKTESGIVLPEKAKEKPQEGEVVAVGSGKTLDDGSKVEPEVKAGDKVVYSKFAGNEVEVDGE
EYLIMRQDDILAVIE

Sequences:

>Translated_95_residues
MNLKPLGDRIVIKILEAEEKTESGIVLPEKAKEKPQEGEVVAVGSGKTLDDGSKVEPEVKAGDKVVYSKFAGNEVEVDGE
EYLIMRQDDILAVIE
>Mature_95_residues
MNLKPLGDRIVIKILEAEEKTESGIVLPEKAKEKPQEGEVVAVGSGKTLDDGSKVEPEVKAGDKVVYSKFAGNEVEVDGE
EYLIMRQDDILAVIE

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family

Homologues:

Organism=Escherichia coli, GI1790585, Length=96, Percent_Identity=44.7916666666667, Blast_Score=78, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17555568, Length=94, Percent_Identity=40.4255319148936, Blast_Score=72, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6324594, Length=91, Percent_Identity=43.956043956044, Blast_Score=76, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21356029, Length=94, Percent_Identity=44.6808510638298, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21358317, Length=93, Percent_Identity=40.8602150537634, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): CH10_NATTJ (B2A5V2)

Other databases:

- EMBL:   CP001034
- RefSeq:   YP_001916633.1
- ProteinModelPortal:   B2A5V2
- SMR:   B2A5V2
- GeneID:   6315274
- GenomeReviews:   CP001034_GR
- KEGG:   nth:Nther_0449
- HOGENOM:   HBG703377
- OMA:   QDRIIVK
- GO:   GO:0005737
- HAMAP:   MF_00580
- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032
- Gene3D:   G3DSA:2.30.33.40
- PANTHER:   PTHR10772
- PRINTS:   PR00297
- SMART:   SM00883

Pfam domain/function: PF00166 Cpn10; SSF50129 GroES_like

EC number: NA

Molecular weight: Translated: 10356; Mature: 10356

Theoretical pI: Translated: 4.21; Mature: 4.21

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLKPLGDRIVIKILEAEEKTESGIVLPEKAKEKPQEGEVVAVGSGKTLDDGSKVEPEVK
CCCCCCCCEEEEEEECCCCCCCCCEECCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCC
AGDKVVYSKFAGNEVEVDGEEYLIMRQDDILAVIE
CCCEEEEEECCCCEEEECCCEEEEEECCCEEEEEC
>Mature Secondary Structure
MNLKPLGDRIVIKILEAEEKTESGIVLPEKAKEKPQEGEVVAVGSGKTLDDGSKVEPEVK
CCCCCCCCEEEEEEECCCCCCCCCEECCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCC
AGDKVVYSKFAGNEVEVDGEEYLIMRQDDILAVIE
CCCEEEEEECCCCEEEECCCEEEEEECCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA