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The map label for this gene is mog [H]

Identifier: 188585087

GI number: 188585087

Start: 472614

End: 473126

Strand: Direct

Name: mog [H]

Synonym: Nther_0448

Alternate gene names: 188585087

Gene position: 472614-473126 (Clockwise)

Preceding gene: 188585086

Following gene: 188585088

Centisome position: 14.93

GC content: 39.38

Gene sequence:

>513_bases
ATGACTTTGTATAAAGCAGGGATAATTACTGCTAGTGATAGTGGTGCTCAAGGAAAACGCGTTGATGAGAGTGGCAAGCT
ATTAAAGCAGTATTTAGAAAATAGCGATATCGGCATTAATGTGGAAGAATATCAGATTGTTCCAGATGATCGCAAAAAAC
TTGGATCTCTAATGGAAGATTGGGTTAGACAAGGTATAGATCTGATTCTTACAACTGGAGGAACAGGTTTAAGCCCTAGA
GATTTTACACCTGAAGCTACAGAGGATGTAATTGATAAACAGGTGCCTGGTTTTCAAGAAGAGATGAGGCGTATGAGTAT
CGAAAAAACACCTCATGGAATGTTGAGTAGAGGGGTTGCCGGTATAAGAAACCAAACGCTGATTATAAATTTCCCAGGAA
GCCCAAAGGCTGTCACCGAGTGTTTTAATACTGTTAAACCTGCCTTATCCCATGCCTTAGAAACGTTAACAGGCCAAGCT
AAAAACTGTGCCCAAAAAAATAATGCAAATTAA

Upstream 100 bases:

>100_bases
TGATTAGAAGTGAGGAGTTCAAGCACTCTATTGATGAATTGTCGGGATATGATCTATCTGCAAGTGGTGAGATATTACAC
TGTTAAGTGAGGTGAATGGG

Downstream 100 bases:

>100_bases
TGGTATAAAATTGAAAATATAGGCAAGAATAATGATTGTGGGCGAATGGTTGTCTAAAAAAATGTTTAGTGGAGCTAAAA
TGAGGAAGTGAGAGATAATT

Product: molybdenum cofactor synthesis domain protein

Products: NA

Alternate protein names: MPT adenylyltransferase [H]

Number of amino acids: Translated: 170; Mature: 169

Protein sequence:

>170_residues
MTLYKAGIITASDSGAQGKRVDESGKLLKQYLENSDIGINVEEYQIVPDDRKKLGSLMEDWVRQGIDLILTTGGTGLSPR
DFTPEATEDVIDKQVPGFQEEMRRMSIEKTPHGMLSRGVAGIRNQTLIINFPGSPKAVTECFNTVKPALSHALETLTGQA
KNCAQKNNAN

Sequences:

>Translated_170_residues
MTLYKAGIITASDSGAQGKRVDESGKLLKQYLENSDIGINVEEYQIVPDDRKKLGSLMEDWVRQGIDLILTTGGTGLSPR
DFTPEATEDVIDKQVPGFQEEMRRMSIEKTPHGMLSRGVAGIRNQTLIINFPGSPKAVTECFNTVKPALSHALETLTGQA
KNCAQKNNAN
>Mature_169_residues
TLYKAGIITASDSGAQGKRVDESGKLLKQYLENSDIGINVEEYQIVPDDRKKLGSLMEDWVRQGIDLILTTGGTGLSPRD
FTPEATEDVIDKQVPGFQEEMRRMSIEKTPHGMLSRGVAGIRNQTLIINFPGSPKAVTECFNTVKPALSHALETLTGQAK
NCAQKNNAN

Specific function: Catalyzes the adenylation of molybdopterin as part of the biosynthesis of the molybdenum-cofactor [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family [H]

Homologues:

Organism=Homo sapiens, GI66932975, Length=154, Percent_Identity=46.1038961038961, Blast_Score=135, Evalue=3e-32,
Organism=Homo sapiens, GI10880983, Length=154, Percent_Identity=46.1038961038961, Blast_Score=134, Evalue=3e-32,
Organism=Escherichia coli, GI1786190, Length=149, Percent_Identity=36.241610738255, Blast_Score=99, Evalue=1e-22,
Organism=Escherichia coli, GI1787000, Length=148, Percent_Identity=34.4594594594595, Blast_Score=76, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17564954, Length=158, Percent_Identity=41.1392405063291, Blast_Score=119, Evalue=9e-28,
Organism=Drosophila melanogaster, GI17136978, Length=164, Percent_Identity=39.6341463414634, Blast_Score=116, Evalue=8e-27,
Organism=Drosophila melanogaster, GI24638841, Length=164, Percent_Identity=39.6341463414634, Blast_Score=116, Evalue=8e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR008284
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 18578; Mature: 18447

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: PS01078 MOCF_BIOSYNTHESIS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLYKAGIITASDSGAQGKRVDESGKLLKQYLENSDIGINVEEYQIVPDDRKKLGSLMED
CCEECCEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHEEECCCHHHHHHHHHHH
WVRQGIDLILTTGGTGLSPRDFTPEATEDVIDKQVPGFQEEMRRMSIEKTPHGMLSRGVA
HHHCCCEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHH
GIRNQTLIINFPGSPKAVTECFNTVKPALSHALETLTGQAKNCAQKNNAN
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCC
>Mature Secondary Structure 
TLYKAGIITASDSGAQGKRVDESGKLLKQYLENSDIGINVEEYQIVPDDRKKLGSLMED
CEECCEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHEEECCCHHHHHHHHHHH
WVRQGIDLILTTGGTGLSPRDFTPEATEDVIDKQVPGFQEEMRRMSIEKTPHGMLSRGVA
HHHCCCEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHH
GIRNQTLIINFPGSPKAVTECFNTVKPALSHALETLTGQAKNCAQKNNAN
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]