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The map label for this gene is cymR [H]

Identifier: 188584942

GI number: 188584942

Start: 319008

End: 319475

Strand: Direct

Name: cymR [H]

Synonym: Nther_0301

Alternate gene names: 188584942

Gene position: 319008-319475 (Clockwise)

Preceding gene: 188584941

Following gene: 188584943

Centisome position: 10.08

GC content: 37.82

Gene sequence:

>468_bases
GTGTGTGTGAATGTGAAACTGTCTACTAAAGGAGAATATGGAGTAAGGGCTTTAGTCCATTTAGCATGTAATTACAATGA
AGGCCCTATTTCCCTGAGAGAAATAAGCAAAATAGAGGATATATCCTACCAATATTTGGAACAAATTTTTTTAGATCTCA
GAAGAAATTCCTTGGTTTTAAGTGTTCGAGGTGCAAAAGGTGGTTATACTCTTGCAAGTCACCCAAAAGAAATTACAGTC
GGAGATGTTATCAGGGCTGTAGAAGGCCCCATTGCACCAGTTAGTTGTGTGGCCAAGTCAACAAATAGCGAAAATACTGA
ATGTGATAGGTCATCAACATGTGCTCCCAGAGGAGTATGGTTGGAATTGAGAGATAGAATATCTGAAGTATTAGATGAAT
TCACCTTGCAAGATCTAGCCGTTACAGATAATGATATCGAAAAATTAAGGGGGGAACATAATGAATAA

Upstream 100 bases:

>100_bases
ATTTTTTAAACTAAAACCCTAGTATTAAGCTAGACATTTTACACAAAATGTTGGATTATTATAAAAAAATGTGGAAAACT
AAGTTCAGCCGAGAAGAAAG

Downstream 100 bases:

>100_bases
AATTTATCTTGATCATGGAGCTACAACTCCTATGCGTGAAGAAGTATTTGAAACAATGAAACCATATTTACAGGATAATT
TCGGAAATCCTTCCAGTATC

Product: CarD family transcriptional regulator

Products: NA

Alternate protein names: Cysteine metabolism repressor [H]

Number of amino acids: Translated: 155; Mature: 155

Protein sequence:

>155_residues
MCVNVKLSTKGEYGVRALVHLACNYNEGPISLREISKIEDISYQYLEQIFLDLRRNSLVLSVRGAKGGYTLASHPKEITV
GDVIRAVEGPIAPVSCVAKSTNSENTECDRSSTCAPRGVWLELRDRISEVLDEFTLQDLAVTDNDIEKLRGEHNE

Sequences:

>Translated_155_residues
MCVNVKLSTKGEYGVRALVHLACNYNEGPISLREISKIEDISYQYLEQIFLDLRRNSLVLSVRGAKGGYTLASHPKEITV
GDVIRAVEGPIAPVSCVAKSTNSENTECDRSSTCAPRGVWLELRDRISEVLDEFTLQDLAVTDNDIEKLRGEHNE
>Mature_155_residues
MCVNVKLSTKGEYGVRALVHLACNYNEGPISLREISKIEDISYQYLEQIFLDLRRNSLVLSVRGAKGGYTLASHPKEITV
GDVIRAVEGPIAPVSCVAKSTNSENTECDRSSTCAPRGVWLELRDRISEVLDEFTLQDLAVTDNDIEKLRGEHNE

Specific function: Master repressor of cysteine metabolism in B.subtilis. Controls the expression of genes involved either in cysteine synthesis from sulfide (cysK), sulfonates (ssu), or methionine (mccAB) or in cystine uptake (tcyP). Activity of CymR is positively regulate

COG id: COG1959

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH rrf2-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788880, Length=135, Percent_Identity=37.7777777777778, Blast_Score=91, Evalue=4e-20,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000944 [H]

Pfam domain/function: PF02082 Rrf2 [H]

EC number: NA

Molecular weight: Translated: 17225; Mature: 17225

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS01332 UPF0074

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCVNVKLSTKGEYGVRALVHLACNYNEGPISLREISKIEDISYQYLEQIFLDLRRNSLVL
CEEEEEECCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCEEEE
SVRGAKGGYTLASHPKEITVGDVIRAVEGPIAPVSCVAKSTNSENTECDRSSTCAPRGVW
EEECCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCHH
LELRDRISEVLDEFTLQDLAVTDNDIEKLRGEHNE
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCC
>Mature Secondary Structure
MCVNVKLSTKGEYGVRALVHLACNYNEGPISLREISKIEDISYQYLEQIFLDLRRNSLVL
CEEEEEECCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCEEEE
SVRGAKGGYTLASHPKEITVGDVIRAVEGPIAPVSCVAKSTNSENTECDRSSTCAPRGVW
EEECCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCHH
LELRDRISEVLDEFTLQDLAVTDNDIEKLRGEHNE
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]