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The map label for this gene is acpS

Identifier: 188584941

GI number: 188584941

Start: 318462

End: 318839

Strand: Direct

Name: acpS

Synonym: Nther_0300

Alternate gene names: 188584941

Gene position: 318462-318839 (Clockwise)

Preceding gene: 188584940

Following gene: 188584942

Centisome position: 10.06

GC content: 33.6

Gene sequence:

>378_bases
GTGATAATAGGATTAGGTGTAGATATCATAGAGATTGCTAGGATCAAAAAAGTATATAATAAATTTCCCTGGAAATTTGT
AAATAAACTTTTTTCTGATAGGGAGCAAAAAAAGCTTATGACTTTACATAATCCAAATGAATACATATCAGGTCGTTTTG
CTGCCAAAGAGGCAGTTGCTAAAGCTTTTGGAACGGGAATAGGCCAAGTTAGATGGAAAGATATCGAAATTTTAACTGCT
GATGAAGGATATCCAGTTGTAAATTTACACGGCGAGGCTTTAAATAAAGCCGAGGAATTGGGAGTAACAAAAGTTTATTT
ATCTATTTCACATTCTAAAACTTCAGCAGTTGCCAATGCCATTTTATGGAGTGATTAA

Upstream 100 bases:

>100_bases
AAGTATAGTTGGCTTTAATGTCCTGGAGGAATTAACAAGTTATTTACAAGTTGGAATTTATTAATTAGTATTGTTTAATG
ATATTTGGGGAGGTAAGCGT

Downstream 100 bases:

>100_bases
GTTAAACTTGACAATTATTAAACAAAACTATAAAATGGAAACAAATCCTAACTAAAGAGGTCGGGATTATTTTTTAAACT
AAAACCCTAGTATTAAGCTA

Product: holo-acyl-carrier-protein synthase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 125; Mature: 125

Protein sequence:

>125_residues
MIIGLGVDIIEIARIKKVYNKFPWKFVNKLFSDREQKKLMTLHNPNEYISGRFAAKEAVAKAFGTGIGQVRWKDIEILTA
DEGYPVVNLHGEALNKAEELGVTKVYLSISHSKTSAVANAILWSD

Sequences:

>Translated_125_residues
MIIGLGVDIIEIARIKKVYNKFPWKFVNKLFSDREQKKLMTLHNPNEYISGRFAAKEAVAKAFGTGIGQVRWKDIEILTA
DEGYPVVNLHGEALNKAEELGVTKVYLSISHSKTSAVANAILWSD
>Mature_125_residues
MIIGLGVDIIEIARIKKVYNKFPWKFVNKLFSDREQKKLMTLHNPNEYISGRFAAKEAVAKAFGTGIGQVRWKDIEILTA
DEGYPVVNLHGEALNKAEELGVTKVYLSISHSKTSAVANAILWSD

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=124, Percent_Identity=39.5161290322581, Blast_Score=87, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6325025, Length=120, Percent_Identity=38.3333333333333, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_NATTJ (B2A4X6)

Other databases:

- EMBL:   CP001034
- RefSeq:   YP_001916486.1
- ProteinModelPortal:   B2A4X6
- SMR:   B2A4X6
- GeneID:   6316133
- GenomeReviews:   CP001034_GR
- KEGG:   nth:Nther_0300
- HOGENOM:   HBG734479
- OMA:   NSSAIAY
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 13976; Mature: 13976

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIGLGVDIIEIARIKKVYNKFPWKFVNKLFSDREQKKLMTLHNPNEYISGRFAAKEAVA
CEEECCCHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHEEEECCCCHHHCCHHHHHHHHH
KAFGTGIGQVRWKDIEILTADEGYPVVNLHGEALNKAEELGVTKVYLSISHSKTSAVANA
HHHCCCCCCEEEEEEEEEECCCCCCEEEECHHHHHHHHHCCEEEEEEEECCCHHHHHHHH
ILWSD
HCCCC
>Mature Secondary Structure
MIIGLGVDIIEIARIKKVYNKFPWKFVNKLFSDREQKKLMTLHNPNEYISGRFAAKEAVA
CEEECCCHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHEEEECCCCHHHCCHHHHHHHHH
KAFGTGIGQVRWKDIEILTADEGYPVVNLHGEALNKAEELGVTKVYLSISHSKTSAVANA
HHHCCCCCCEEEEEEEEEECCCCCCEEEECHHHHHHHHHCCEEEEEEEECCCHHHHHHHH
ILWSD
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA