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The map label for this gene is 188584911

Identifier: 188584911

GI number: 188584911

Start: 284240

End: 285442

Strand: Reverse

Name: 188584911

Synonym: Nther_0270

Alternate gene names: NA

Gene position: 285442-284240 (Counterclockwise)

Preceding gene: 188584913

Following gene: 188584898

Centisome position: 9.02

GC content: 37.66

Gene sequence:

>1203_bases
ATGATTGAAAGTATTTTGATTATACTAATTGCCGGCTTCATTATGGGAAAAGCTTTTGAAAAGTTAAACCTTCCAGGTTT
GTTAGGAATGCTTCTTGCGGGTATTTTGTTAGGACCAAATTATTTAGATTTGATTTCAAGTGAAATTTTGGCTATCTCTG
ATGACATTAGGTTGCTTGCATTGATTTTAATCTTGCTTAGAGCGGGTCTTGGATTAAGGCGTGAAACTTTAAATAAGGTG
GGAGTACTCTCTCTTAAGTTAGGTTCGCTGCCATGTTTAATGGAAGGGTTTACTGTACTTTTATTAGCTTATTACCTATT
TGAGCTTGGGTTTGTCGAAGCTGGTATATTGGGTTTTATTATAGCAGCTGTTAGCCCAGCGGTAATAGTCCCCTCTATGT
TGAAATTAAAAGATAGAGGCCTTGGTAAAGATAAAGGGATTCCTGTAATGATTTTAGCTGGGGCTTCAATTGATGATGTA
TTTGCCATAACTCTTATCTCTATTTTTCTTGGCCTTGTCAATGGAGGTGCCGGTGGCACCCTTTTAAGTTTACTAGCTAT
TCCGAGAGAGATAATAGGAGGTATCTTATTTGGCCTCTTCGTAGGTTTTATCCTGACAAAGATCTATCAAAAATTTGAAA
TGGCCGACAGTGATAGAATGGTAGTATTAGCAGTAGGAGCTCTTTTTGCCTATGTTGTAAGCTCCTATTTACAAGTTGCC
GGCCTACTTGCCATCATGATAGCTGGTGCTTACCTTTTAGAAAAACATAAATTGTTTGCAGAGGAATTTTCAAAGAAGCT
AAAAGGAGTATGGTCTTTTGGAGAGATATTCTTATTTGTATTAATCGGCTCTATTGTAGATGTATCTTTAGCAATTAGTG
CGGGACCACTGGGAATTTTAATAATTACAGTCGGAGTATTTATAAGAATGTTGGGAGTCTATATATCAACTTTAGGCTCA
AATTTAAATCCTAAAGAAAGACTTTTCTGCGGAATTTCATACAGCCCTAAGGCTACCGTTCAAGCTGCAATGGGTGGAGT
TCCTTTGTCAATGGGGCTACCCGGAGGAGAATTAATCCTGGCACTAGCCGTTTTGTCGGTAATCTATACAGCACCTTTAG
GTGCACTTGGAATTAACTTTTTTGCCGATAAACTTCTTGATAGTGAAAGTGATGAAACTGCTGAACTTTCCTCAATAGAA
TAA

Upstream 100 bases:

>100_bases
GAGCTCGCCAGGATTAAATTCCAAACTGCTTTCTTAGAAGCTAATGGCTCCTACCCTATCAGGGTAGGAGTCTATTTTTT
TAAGAAAGGGATGATTTACA

Downstream 100 bases:

>100_bases
TAATCTGATAATCAATTAAAATATCTACCCCAAGTAGTGAACTTTTGGATCTAACAGATCATTTTAGCCACTAAGGGGTA
GATTAGATTTGGTGTGAGAG

Product: sodium/hydrogen exchanger

Products: NA

Alternate protein names: Na(+)/H(+) Antiporter; Transporter CPA2 Family; Na+/H+ Antiporter; Sodium/Proton Antiporter CPA1 Family; Na+/H+-Exchanging Protein; Sodium/Hydrogen Antiporter; Sodium/Hydrogen Exchanger Family Protein; Na+/H+-Exchanging ProteinNa+/H+ Antiporter; Monovalent CationProton Antiporter-2 Family Protein; Transporter Monovalent CationProton Antiporter-2 Family; Sodium/Hydrogen Exchanger/Universal Stress Family Protein

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MIESILIILIAGFIMGKAFEKLNLPGLLGMLLAGILLGPNYLDLISSEILAISDDIRLLALILILLRAGLGLRRETLNKV
GVLSLKLGSLPCLMEGFTVLLLAYYLFELGFVEAGILGFIIAAVSPAVIVPSMLKLKDRGLGKDKGIPVMILAGASIDDV
FAITLISIFLGLVNGGAGGTLLSLLAIPREIIGGILFGLFVGFILTKIYQKFEMADSDRMVVLAVGALFAYVVSSYLQVA
GLLAIMIAGAYLLEKHKLFAEEFSKKLKGVWSFGEIFLFVLIGSIVDVSLAISAGPLGILIITVGVFIRMLGVYISTLGS
NLNPKERLFCGISYSPKATVQAAMGGVPLSMGLPGGELILALAVLSVIYTAPLGALGINFFADKLLDSESDETAELSSIE

Sequences:

>Translated_400_residues
MIESILIILIAGFIMGKAFEKLNLPGLLGMLLAGILLGPNYLDLISSEILAISDDIRLLALILILLRAGLGLRRETLNKV
GVLSLKLGSLPCLMEGFTVLLLAYYLFELGFVEAGILGFIIAAVSPAVIVPSMLKLKDRGLGKDKGIPVMILAGASIDDV
FAITLISIFLGLVNGGAGGTLLSLLAIPREIIGGILFGLFVGFILTKIYQKFEMADSDRMVVLAVGALFAYVVSSYLQVA
GLLAIMIAGAYLLEKHKLFAEEFSKKLKGVWSFGEIFLFVLIGSIVDVSLAISAGPLGILIITVGVFIRMLGVYISTLGS
NLNPKERLFCGISYSPKATVQAAMGGVPLSMGLPGGELILALAVLSVIYTAPLGALGINFFADKLLDSESDETAELSSIE
>Mature_400_residues
MIESILIILIAGFIMGKAFEKLNLPGLLGMLLAGILLGPNYLDLISSEILAISDDIRLLALILILLRAGLGLRRETLNKV
GVLSLKLGSLPCLMEGFTVLLLAYYLFELGFVEAGILGFIIAAVSPAVIVPSMLKLKDRGLGKDKGIPVMILAGASIDDV
FAITLISIFLGLVNGGAGGTLLSLLAIPREIIGGILFGLFVGFILTKIYQKFEMADSDRMVVLAVGALFAYVVSSYLQVA
GLLAIMIAGAYLLEKHKLFAEEFSKKLKGVWSFGEIFLFVLIGSIVDVSLAISAGPLGILIITVGVFIRMLGVYISTLGS
NLNPKERLFCGISYSPKATVQAAMGGVPLSMGLPGGELILALAVLSVIYTAPLGALGINFFADKLLDSESDETAELSSIE

Specific function: Unknown

COG id: COG0025

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI47271479, Length=365, Percent_Identity=33.972602739726, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI66793392, Length=368, Percent_Identity=30.4347826086957, Blast_Score=149, Evalue=4e-36,
Organism=Homo sapiens, GI154937338, Length=299, Percent_Identity=31.438127090301, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17567635, Length=411, Percent_Identity=29.4403892944039, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI32566724, Length=406, Percent_Identity=28.3251231527094, Blast_Score=111, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI25152227, Length=418, Percent_Identity=22.9665071770335, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI20129297, Length=394, Percent_Identity=32.48730964467, Blast_Score=148, Evalue=6e-36,
Organism=Drosophila melanogaster, GI45550940, Length=394, Percent_Identity=32.48730964467, Blast_Score=148, Evalue=6e-36,
Organism=Drosophila melanogaster, GI24649169, Length=388, Percent_Identity=31.1855670103093, Blast_Score=119, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 42288; Mature: 42288

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIESILIILIAGFIMGKAFEKLNLPGLLGMLLAGILLGPNYLDLISSEILAISDDIRLLA
CHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHH
LILILLRAGLGLRRETLNKVGVLSLKLGSLPCLMEGFTVLLLAYYLFELGFVEAGILGFI
HHHHHHHCCCCHHHHHHHHHCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAAVSPAVIVPSMLKLKDRGLGKDKGIPVMILAGASIDDVFAITLISIFLGLVNGGAGGT
HHHHCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCHHH
LLSLLAIPREIIGGILFGLFVGFILTKIYQKFEMADSDRMVVLAVGALFAYVVSSYLQVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
GLLAIMIAGAYLLEKHKLFAEEFSKKLKGVWSFGEIFLFVLIGSIVDVSLAISAGPLGIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
IITVGVFIRMLGVYISTLGSNLNPKERLFCGISYSPKATVQAAMGGVPLSMGLPGGELIL
HHHHHHHHHHHHHHHHHHCCCCCCHHHEEECCCCCCCHHHHHHHCCCCEECCCCHHHHHH
ALAVLSVIYTAPLGALGINFFADKLLDSESDETAELSSIE
HHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCHHCCCC
>Mature Secondary Structure
MIESILIILIAGFIMGKAFEKLNLPGLLGMLLAGILLGPNYLDLISSEILAISDDIRLLA
CHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHH
LILILLRAGLGLRRETLNKVGVLSLKLGSLPCLMEGFTVLLLAYYLFELGFVEAGILGFI
HHHHHHHCCCCHHHHHHHHHCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAAVSPAVIVPSMLKLKDRGLGKDKGIPVMILAGASIDDVFAITLISIFLGLVNGGAGGT
HHHHCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCHHH
LLSLLAIPREIIGGILFGLFVGFILTKIYQKFEMADSDRMVVLAVGALFAYVVSSYLQVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
GLLAIMIAGAYLLEKHKLFAEEFSKKLKGVWSFGEIFLFVLIGSIVDVSLAISAGPLGIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
IITVGVFIRMLGVYISTLGSNLNPKERLFCGISYSPKATVQAAMGGVPLSMGLPGGELIL
HHHHHHHHHHHHHHHHHHCCCCCCHHHEEECCCCCCCHHHHHHHCCCCEECCCCHHHHHH
ALAVLSVIYTAPLGALGINFFADKLLDSESDETAELSSIE
HHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA