| Definition | Helicobacter pylori Shi470, complete genome. |
|---|---|
| Accession | NC_010698 |
| Length | 1,608,548 |
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The map label for this gene is hsdM [H]
Identifier: 188528306
GI number: 188528306
Start: 1533747
End: 1536209
Strand: Reverse
Name: hsdM [H]
Synonym: HPSH_07890
Alternate gene names: 188528306
Gene position: 1536209-1533747 (Counterclockwise)
Preceding gene: 188528309
Following gene: 188528305
Centisome position: 95.5
GC content: 38.0
Gene sequence:
>2463_bases ATGGCGATCAAAAAAAGCGAATTGTATAGCTCTTTATGGGCTGGGGCGGATAGTTTAAGGGGCGGAATGGATGCGAGCGA GTATAAAAACTATGTTTTGAACCTGCTTTTTTTAAAATACATCAGCGATAAAGCCAGAAATGACGCCAAAAACAATACTG ATAGCGAAATAGAAGTGCCGCAAGGGTGTTTTTATGAAGACATTCTCGCTTTAGAGGGCGATAAAGAAATAGGCGACAAG CTCAATAAAATCATCGCAGAAATCGCAGAGCAAAACGACTTAAAAGGCGTGATTGACAGCGTGGATTTTAACGATAACAC TAAGCTTGGAGAGGGTAAAGCGATGACAGACACCCTTTCTAATTTGGTTAAAATCTTTGCCGATTTGAGTTTGGGCGCGC ATGGGGCTTTAGACGATGATTTATTGGGCGATGCTTACGAATATTTAATGCGCCACTTTGCCAGCGAATCCGGTAAATCC AAAGGGCAGTTTTACACCCCTAGCGAAGTTTCGCTTTTATTGTCCCTTTTGCTTGGCATTGATGCAAACACCAAACAAGA TAAAAGCATCTATGACCCCACTTGCGGGAGCGGTTCGTTATTGTTAAAAGCTTCTAGCTTGGCGGGCAAAAACGGCTTAA CTATCTATGGTCAAGAAAAAGACATTTCCACAACAGCCCTTTGTAAAATGAATATGATTTTACACAATAGCGCTGATGCT GATATTGCTAAAGGGGGTTCTAGCACCCTTTCTAACCCCTTTTTTATTAAAAACGGCATGCTGCAAACCTTTGATTATGT CGTGGCTAACCCTCCCTTTAGCTTGAAAAACTGGACTGATGGGCTAAATATAGACCCTAAAAGCAAGCAAGTCATTAACG ATAGTTTCAATCGTTTTGAAGACGGCACGCCCCCTGAAAAAAATGGCGATTTCGCTTTTTTGCTCCATATCATCAAATCC TTAAAAGACACAGGCAAAGGGGCAGTGATTTTACCCCATGGGGTGCTATTTAGAGGGAATGCTGAGGGCGTAATTAGAAA AAATCTTTTAACAAAAGGCTATATTAAGGGCGCGATAGGCCTAGCCCCTAATCTATTCTATGGCACTTCCATTCCTGCAT GCGTGATTGTTTTAGACAAAGAAAACGCGCGCGCCAGAAAGGGCGTTTTTTTGATAGATGCGAGCAAGGATTTTAAAAAA GACGGCAATAAAAACCGCTTAAGAGAGCAAGATGTCCAAAAAATGATAGACGCTTTTAACGCTTTAAAAGAAATCCCTTA TTATTCCAAAATGGTAAGCCTAGAAGAAATTAGCACTAACGACTACAACTTGAATATCGCGCGCTACATTGCCGCCAAAC AAGAATCAGAAAAAGACTTGTTCGCTTTAATCAACAGCCACAAGGCTAGTTATTTGCCCAAAAACGAAATTGAAGCCTAC GCCCCTTATTTTCAAGTGTTTAAAGAGCTTAAAAACACGCTTTTTAAAAAGAGCGATAAAGAGGGTTATTACGCTTTAAA AACAGAATGCCAAAACATTAAAGATCTAATCACCCAAAGCTCAGAATTCCAAGCTTTCCACGCTTCTGTTTTAAACGCTT TTGACCGATTGAATCTGTTTGAAACTTTTGATCATTTAGAGCCAGGTTTTAACCCAAAAACCCTCATAGAGAGCGTTTGC TCAAAGGTTTTAAAAGAATTTGAAAAGGTAGAAATTTTAGACAAATACGGCGTGTATCAGCTCTTTAAAGATTACTACAA TGAAGTTTTACAAGACGATTGGTTCCTTCTTTCATTCAATGATTTTTTGAGCGCTAAAGAATTAAGGGAATTAAACCCCC TAAAAGACAAAAACAAAAAAGCCAACTATTTAGAAGAGCCGGATTTTGTCATTCAAAAAACCTACTATAAAAGTGATCTA ATCCCTAAAAACTTGATCAAACAACGCTTTTTTGAAAAAGAAGCAAAAGAATTAGAACAATTAGAAAACGCCCTCAGTGA AAAAGAAGCTGATTTTGAAGAATTTATAGAAGAGCATTCTAGTGAAGAAGGGCTTTTTTATGAATTGAAAATCAATGAAA GCGTTTTGAAAAAAGAGCTAAAAAACGCCACCGATTTAGAAGATAAAAAAATCCTAAAAACCGCTTTAGAATTGCTAGAA GCTAAAAACAAGGCACTAAAAATGAAAAATAAAGCCCATGAGGAGCTGGAATTAAAAGCGTTCCACCAGTATAAAAACTT GAAATTAGGCGAAATTAAGAATCTCATCATCCAAGACAAATGGCTTAAGAGCCTAAAAAACGCCCTAGAAAACAAAATTT TAAAACGCATCAACGCTTTTACTAGCGCCCTTAATGAAATCATTTCAAACTACTCTAACAGCTTGCTAGAATTAGACAAA GAAGTCAAAGAGAGCGAATCAAAAGTTTTAGAGCATTTGAAAGATTTGGGGTTAATGGGGTGA
Upstream 100 bases:
>100_bases TTGTTTTTGAACTTCTTTTTCTGTTTTCACCATAAAACCCCTTAAGAGCGCTTTTTATCGCTTTATATTATAATCCTAAA AACAAAATAGGGCGATTAAA
Downstream 100 bases:
>100_bases TAGAACGCATGGACGCATTAATGTTGCCCTTAAATTGGCAAAGAGTGAGGCTTGGGGATATATTTTTCATTACGGCTGGA GGCGATTTATCTAAGCCACA
Product: type I restriction enzyme M protein (hsdM)
Products: NA
Alternate protein names: M.EcoR124II [H]
Number of amino acids: Translated: 820; Mature: 819
Protein sequence:
>820_residues MAIKKSELYSSLWAGADSLRGGMDASEYKNYVLNLLFLKYISDKARNDAKNNTDSEIEVPQGCFYEDILALEGDKEIGDK LNKIIAEIAEQNDLKGVIDSVDFNDNTKLGEGKAMTDTLSNLVKIFADLSLGAHGALDDDLLGDAYEYLMRHFASESGKS KGQFYTPSEVSLLLSLLLGIDANTKQDKSIYDPTCGSGSLLLKASSLAGKNGLTIYGQEKDISTTALCKMNMILHNSADA DIAKGGSSTLSNPFFIKNGMLQTFDYVVANPPFSLKNWTDGLNIDPKSKQVINDSFNRFEDGTPPEKNGDFAFLLHIIKS LKDTGKGAVILPHGVLFRGNAEGVIRKNLLTKGYIKGAIGLAPNLFYGTSIPACVIVLDKENARARKGVFLIDASKDFKK DGNKNRLREQDVQKMIDAFNALKEIPYYSKMVSLEEISTNDYNLNIARYIAAKQESEKDLFALINSHKASYLPKNEIEAY APYFQVFKELKNTLFKKSDKEGYYALKTECQNIKDLITQSSEFQAFHASVLNAFDRLNLFETFDHLEPGFNPKTLIESVC SKVLKEFEKVEILDKYGVYQLFKDYYNEVLQDDWFLLSFNDFLSAKELRELNPLKDKNKKANYLEEPDFVIQKTYYKSDL IPKNLIKQRFFEKEAKELEQLENALSEKEADFEEFIEEHSSEEGLFYELKINESVLKKELKNATDLEDKKILKTALELLE AKNKALKMKNKAHEELELKAFHQYKNLKLGEIKNLIIQDKWLKSLKNALENKILKRINAFTSALNEIISNYSNSLLELDK EVKESESKVLEHLKDLGLMG
Sequences:
>Translated_820_residues MAIKKSELYSSLWAGADSLRGGMDASEYKNYVLNLLFLKYISDKARNDAKNNTDSEIEVPQGCFYEDILALEGDKEIGDK LNKIIAEIAEQNDLKGVIDSVDFNDNTKLGEGKAMTDTLSNLVKIFADLSLGAHGALDDDLLGDAYEYLMRHFASESGKS KGQFYTPSEVSLLLSLLLGIDANTKQDKSIYDPTCGSGSLLLKASSLAGKNGLTIYGQEKDISTTALCKMNMILHNSADA DIAKGGSSTLSNPFFIKNGMLQTFDYVVANPPFSLKNWTDGLNIDPKSKQVINDSFNRFEDGTPPEKNGDFAFLLHIIKS LKDTGKGAVILPHGVLFRGNAEGVIRKNLLTKGYIKGAIGLAPNLFYGTSIPACVIVLDKENARARKGVFLIDASKDFKK DGNKNRLREQDVQKMIDAFNALKEIPYYSKMVSLEEISTNDYNLNIARYIAAKQESEKDLFALINSHKASYLPKNEIEAY APYFQVFKELKNTLFKKSDKEGYYALKTECQNIKDLITQSSEFQAFHASVLNAFDRLNLFETFDHLEPGFNPKTLIESVC SKVLKEFEKVEILDKYGVYQLFKDYYNEVLQDDWFLLSFNDFLSAKELRELNPLKDKNKKANYLEEPDFVIQKTYYKSDL IPKNLIKQRFFEKEAKELEQLENALSEKEADFEEFIEEHSSEEGLFYELKINESVLKKELKNATDLEDKKILKTALELLE AKNKALKMKNKAHEELELKAFHQYKNLKLGEIKNLIIQDKWLKSLKNALENKILKRINAFTSALNEIISNYSNSLLELDK EVKESESKVLEHLKDLGLMG >Mature_819_residues AIKKSELYSSLWAGADSLRGGMDASEYKNYVLNLLFLKYISDKARNDAKNNTDSEIEVPQGCFYEDILALEGDKEIGDKL NKIIAEIAEQNDLKGVIDSVDFNDNTKLGEGKAMTDTLSNLVKIFADLSLGAHGALDDDLLGDAYEYLMRHFASESGKSK GQFYTPSEVSLLLSLLLGIDANTKQDKSIYDPTCGSGSLLLKASSLAGKNGLTIYGQEKDISTTALCKMNMILHNSADAD IAKGGSSTLSNPFFIKNGMLQTFDYVVANPPFSLKNWTDGLNIDPKSKQVINDSFNRFEDGTPPEKNGDFAFLLHIIKSL KDTGKGAVILPHGVLFRGNAEGVIRKNLLTKGYIKGAIGLAPNLFYGTSIPACVIVLDKENARARKGVFLIDASKDFKKD GNKNRLREQDVQKMIDAFNALKEIPYYSKMVSLEEISTNDYNLNIARYIAAKQESEKDLFALINSHKASYLPKNEIEAYA PYFQVFKELKNTLFKKSDKEGYYALKTECQNIKDLITQSSEFQAFHASVLNAFDRLNLFETFDHLEPGFNPKTLIESVCS KVLKEFEKVEILDKYGVYQLFKDYYNEVLQDDWFLLSFNDFLSAKELRELNPLKDKNKKANYLEEPDFVIQKTYYKSDLI PKNLIKQRFFEKEAKELEQLENALSEKEADFEEFIEEHSSEEGLFYELKINESVLKKELKNATDLEDKKILKTALELLEA KNKALKMKNKAHEELELKAFHQYKNLKLGEIKNLIIQDKWLKSLKNALENKILKRINAFTSALNEIISNYSNSLLELDKE VKESESKVLEHLKDLGLMG
Specific function: Methylation of specific adenine residues; required for both restriction and modification activities. The EcoR124/3 I enzyme recognizes 5'-GAAN(7)RTCG-3' [H]
COG id: COG0286
COG function: function code V; Type I restriction-modification system methyltransferase subunit
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]
Homologues:
Organism=Escherichia coli, GI1790808, Length=397, Percent_Identity=26.9521410579345, Blast_Score=113, Evalue=5e-26,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR022749 - InterPro: IPR003356 - InterPro: IPR002052 - InterPro: IPR002296 - InterPro: IPR004546 [H]
Pfam domain/function: PF12161 HsdM_N; PF02384 N6_Mtase [H]
EC number: =2.1.1.72 [H]
Molecular weight: Translated: 92753; Mature: 92621
Theoretical pI: Translated: 5.35; Mature: 5.35
Prosite motif: PS00092 N6_MTASE
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.7 %Cys (Translated Protein) 1.3 %Met (Translated Protein) 2.1 %Cys+Met (Translated Protein) 0.7 %Cys (Mature Protein) 1.2 %Met (Mature Protein) 2.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MAIKKSELYSSLWAGADSLRGGMDASEYKNYVLNLLFLKYISDKARNDAKNNTDSEIEVP CCCCHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC QGCFYEDILALEGDKEIGDKLNKIIAEIAEQNDLKGVIDSVDFNDNTKLGEGKAMTDTLS CCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCHHHHHHH NLVKIFADLSLGAHGALDDDLLGDAYEYLMRHFASESGKSKGQFYTPSEVSLLLSLLLGI HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCC DANTKQDKSIYDPTCGSGSLLLKASSLAGKNGLTIYGQEKDISTTALCKMNMILHNSADA CCCCCCCCCCCCCCCCCCCEEEEEHHCCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCC DIAKGGSSTLSNPFFIKNGMLQTFDYVVANPPFSLKNWTDGLNIDPKSKQVINDSFNRFE HHHCCCCCCCCCCEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCC DGTPPEKNGDFAFLLHIIKSLKDTGKGAVILPHGVLFRGNAEGVIRKNLLTKGYIKGAIG CCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHH LAPNLFYGTSIPACVIVLDKENARARKGVFLIDASKDFKKDGNKNRLREQDVQKMIDAFN CCCCCCCCCCCCEEEEEEECCCCHHHCCEEEEECCHHHHCCCCCCHHHHHHHHHHHHHHH ALKEIPYYSKMVSLEEISTNDYNLNIARYIAAKQESEKDLFALINSHKASYLPKNEIEAY HHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHH APYFQVFKELKNTLFKKSDKEGYYALKTECQNIKDLITQSSEFQAFHASVLNAFDRLNLF HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH ETFDHLEPGFNPKTLIESVCSKVLKEFEKVEILDKYGVYQLFKDYYNEVLQDDWFLLSFN HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHH DFLSAKELRELNPLKDKNKKANYLEEPDFVIQKTYYKSDLIPKNLIKQRFFEKEAKELEQ HHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH LENALSEKEADFEEFIEEHSSEEGLFYELKINESVLKKELKNATDLEDKKILKTALELLE HHHHHHHCCCCHHHHHHHCCCCCCEEEEEECCHHHHHHHHHCCCCCHHHHHHHHHHHHHH AKNKALKMKNKAHEELELKAFHQYKNLKLGEIKNLIIQDKWLKSLKNALENKILKRINAF HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH TSALNEIISNYSNSLLELDKEVKESESKVLEHLKDLGLMG HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC >Mature Secondary Structure AIKKSELYSSLWAGADSLRGGMDASEYKNYVLNLLFLKYISDKARNDAKNNTDSEIEVP CCCHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC QGCFYEDILALEGDKEIGDKLNKIIAEIAEQNDLKGVIDSVDFNDNTKLGEGKAMTDTLS CCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCHHHHHHH NLVKIFADLSLGAHGALDDDLLGDAYEYLMRHFASESGKSKGQFYTPSEVSLLLSLLLGI HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCC DANTKQDKSIYDPTCGSGSLLLKASSLAGKNGLTIYGQEKDISTTALCKMNMILHNSADA CCCCCCCCCCCCCCCCCCCEEEEEHHCCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCC DIAKGGSSTLSNPFFIKNGMLQTFDYVVANPPFSLKNWTDGLNIDPKSKQVINDSFNRFE HHHCCCCCCCCCCEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCC DGTPPEKNGDFAFLLHIIKSLKDTGKGAVILPHGVLFRGNAEGVIRKNLLTKGYIKGAIG CCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHH LAPNLFYGTSIPACVIVLDKENARARKGVFLIDASKDFKKDGNKNRLREQDVQKMIDAFN CCCCCCCCCCCCEEEEEEECCCCHHHCCEEEEECCHHHHCCCCCCHHHHHHHHHHHHHHH ALKEIPYYSKMVSLEEISTNDYNLNIARYIAAKQESEKDLFALINSHKASYLPKNEIEAY HHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHH APYFQVFKELKNTLFKKSDKEGYYALKTECQNIKDLITQSSEFQAFHASVLNAFDRLNLF HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH ETFDHLEPGFNPKTLIESVCSKVLKEFEKVEILDKYGVYQLFKDYYNEVLQDDWFLLSFN HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHH DFLSAKELRELNPLKDKNKKANYLEEPDFVIQKTYYKSDLIPKNLIKQRFFEKEAKELEQ HHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH LENALSEKEADFEEFIEEHSSEEGLFYELKINESVLKKELKNATDLEDKKILKTALELLE HHHHHHHCCCCHHHHHHHCCCCCCEEEEEECCHHHHHHHHHCCCCCHHHHHHHHHHHHHH AKNKALKMKNKAHEELELKAFHQYKNLKLGEIKNLIIQDKWLKSLKNALENKILKRINAF HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH TSALNEIISNYSNSLLELDKEVKESESKVLEHLKDLGLMG HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 2784505 [H]