Click here to switch to the map view.

The map label for this gene is yrbH [C]

Identifier: 188528192

GI number: 188528192

Start: 1419009

End: 1419998

Strand: Reverse

Name: yrbH [C]

Synonym: HPSH_07280

Alternate gene names: 188528192

Gene position: 1419998-1419009 (Counterclockwise)

Preceding gene: 188528193

Following gene: 188528191

Centisome position: 88.28

GC content: 43.43

Gene sequence:

>990_bases
ATGTCCATGCCACTTGATTACAACGCTATCGCCGCGCAAGTCTTAAGAGATGAAGCGAGCGCGCTTTTAGAAAGCGTTAA
GCAATTCCAAAAACCTAACGATTTAGAAGCGATTGTCAAGCTCATTTTAAAAAGCCAAGAAAAAGGGGGTAAGCTTGTGA
TAGTGGGCGTGGGTAAGAGCGCTTTAGTGGCGCAAAAAATCGTTGCTTCTATGCTAAGCACCGGTAACAAAAGCGCGTTT
TTACACCCCACAGAAGCCATGCATGGGGATTTGGGCATGGTGGAAAAAAACGATGTGGTTTTAATGATTAGCTATGGGGG
CGAGTCTTTAGAATTATTGAATCTGGTGAGCCATTTAAAACGCTTGAGCCATAAAATCATCACTTTCACTAAAAGCCCCA
CCAGCTCGCTCTCTAAACTCGGCGATTATTATTTGAGCTTGAAAATTCAAAAAGAAGCTTGCCCGATTAACACCGCTCCA
ACGACTTCCACCACCCTAACTCTAGCGTTAGGCGATGTTTTAATGGCATGTTTGATGCGAGCGAAAAACTTTAGCCAAGA
AGATTTTGCCTCCTTTCATCCGGGCGGGCTTTTAGGCAAAAAACTTTTTGTCAAGGTTAAAGACTTGCTGCAAACCACGA
ATCTCCCCTTAATCGCTCCTAGCACAAGCTTTAAAGACGCGCTCATAGAAATGAGTGAAAAACGCTTAGGCAGCGCGATT
TTAGTCAATGAGGCTAACGAGCTTGTGGGGATTTTGAGCGATGGCGATGTCCGTAGGGCGTTATTGAAAGGGCTTAACTT
AAAGAGCGAAGTGAAGCGTTTTGCCACTTTAAAACCTAAAAGCTTTAAGAATTTAGACGCTCTTCTTTTAGAAGCGTTGG
AATTTTTAGAGCGCCATAAGATCCAGCTTTTAGTGTGCGTGGATGATCGCAATAAGGTTTTAGGGGTCTTGCACTTGCAC
CAACTTTTAGAATTAGGGCTTAAAGCATGA

Upstream 100 bases:

>100_bases
GAAATTTTGAATAGCCCTAAAAAATTAGAAGATCACACTCGTAATTTCATCAGAAAAGCGCTCTTTAAAAAGTTTAGAAA
ATACCCGGCTATCATTTGCC

Downstream 100 bases:

>100_bases
AAGCGAGTATTTATGATTTCACTCTAAAGGAATTGAGCCAGCTTTTAAAACCAAGCTTTAGGGCTAAACAGCTTTATTTG
TGGCTCTATGCGAAGTATAA

Product: polysialic acid capsule expression protein (kpsF)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MSMPLDYNAIAAQVLRDEASALLESVKQFQKPNDLEAIVKLILKSQEKGGKLVIVGVGKSALVAQKIVASMLSTGNKSAF
LHPTEAMHGDLGMVEKNDVVLMISYGGESLELLNLVSHLKRLSHKIITFTKSPTSSLSKLGDYYLSLKIQKEACPINTAP
TTSTTLTLALGDVLMACLMRAKNFSQEDFASFHPGGLLGKKLFVKVKDLLQTTNLPLIAPSTSFKDALIEMSEKRLGSAI
LVNEANELVGILSDGDVRRALLKGLNLKSEVKRFATLKPKSFKNLDALLLEALEFLERHKIQLLVCVDDRNKVLGVLHLH
QLLELGLKA

Sequences:

>Translated_329_residues
MSMPLDYNAIAAQVLRDEASALLESVKQFQKPNDLEAIVKLILKSQEKGGKLVIVGVGKSALVAQKIVASMLSTGNKSAF
LHPTEAMHGDLGMVEKNDVVLMISYGGESLELLNLVSHLKRLSHKIITFTKSPTSSLSKLGDYYLSLKIQKEACPINTAP
TTSTTLTLALGDVLMACLMRAKNFSQEDFASFHPGGLLGKKLFVKVKDLLQTTNLPLIAPSTSFKDALIEMSEKRLGSAI
LVNEANELVGILSDGDVRRALLKGLNLKSEVKRFATLKPKSFKNLDALLLEALEFLERHKIQLLVCVDDRNKVLGVLHLH
QLLELGLKA
>Mature_328_residues
SMPLDYNAIAAQVLRDEASALLESVKQFQKPNDLEAIVKLILKSQEKGGKLVIVGVGKSALVAQKIVASMLSTGNKSAFL
HPTEAMHGDLGMVEKNDVVLMISYGGESLELLNLVSHLKRLSHKIITFTKSPTSSLSKLGDYYLSLKIQKEACPINTAPT
TSTTLTLALGDVLMACLMRAKNFSQEDFASFHPGGLLGKKLFVKVKDLLQTTNLPLIAPSTSFKDALIEMSEKRLGSAIL
VNEANELVGILSDGDVRRALLKGLNLKSEVKRFATLKPKSFKNLDALLLEALEFLERHKIQLLVCVDDRNKVLGVLHLHQ
LLELGLKA

Specific function: Unknown

COG id: COG0794

COG function: function code M; Predicted sugar phosphate isomerase involved in capsule formation

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1789588, Length=326, Percent_Identity=38.6503067484663, Blast_Score=226, Evalue=2e-60,
Organism=Escherichia coli, GI87082151, Length=279, Percent_Identity=36.9175627240143, Blast_Score=198, Evalue=4e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000644
- InterPro:   IPR004800
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00571 CBS; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 35924; Mature: 35793

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: PS00012 PHOSPHOPANTETHEINE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMPLDYNAIAAQVLRDEASALLESVKQFQKPNDLEAIVKLILKSQEKGGKLVIVGVGKS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEEECCCH
ALVAQKIVASMLSTGNKSAFLHPTEAMHGDLGMVEKNDVVLMISYGGESLELLNLVSHLK
HHHHHHHHHHHHHCCCCCEEECCHHHHCCCCCCEECCCEEEEEECCCCHHHHHHHHHHHH
RLSHKIITFTKSPTSSLSKLGDYYLSLKIQKEACPINTAPTTSTTLTLALGDVLMACLMR
HHHHHHEEEECCCHHHHHHHCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
AKNFSQEDFASFHPGGLLGKKLFVKVKDLLQTTNLPLIAPSTSFKDALIEMSEKRLGSAI
HCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHCCCEE
LVNEANELVGILSDGDVRRALLKGLNLKSEVKRFATLKPKSFKNLDALLLEALEFLERHK
EEECCCHHEEECCCCHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCC
IQLLVCVDDRNKVLGVLHLHQLLELGLKA
EEEEEEECCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SMPLDYNAIAAQVLRDEASALLESVKQFQKPNDLEAIVKLILKSQEKGGKLVIVGVGKS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEEECCCH
ALVAQKIVASMLSTGNKSAFLHPTEAMHGDLGMVEKNDVVLMISYGGESLELLNLVSHLK
HHHHHHHHHHHHHCCCCCEEECCHHHHCCCCCCEECCCEEEEEECCCCHHHHHHHHHHHH
RLSHKIITFTKSPTSSLSKLGDYYLSLKIQKEACPINTAPTTSTTLTLALGDVLMACLMR
HHHHHHEEEECCCHHHHHHHCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
AKNFSQEDFASFHPGGLLGKKLFVKVKDLLQTTNLPLIAPSTSFKDALIEMSEKRLGSAI
HCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHCCCEE
LVNEANELVGILSDGDVRRALLKGLNLKSEVKRFATLKPKSFKNLDALLLEALEFLERHK
EEECCCHHEEECCCCHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCC
IQLLVCVDDRNKVLGVLHLHQLLELGLKA
EEEEEEECCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9252185 [H]