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The map label for this gene is nuoH [H]

Identifier: 188528056

GI number: 188528056

Start: 1290051

End: 1291040

Strand: Direct

Name: nuoH [H]

Synonym: HPSH_06565

Alternate gene names: 188528056

Gene position: 1290051-1291040 (Clockwise)

Preceding gene: 188528055

Following gene: 188528057

Centisome position: 80.2

GC content: 42.22

Gene sequence:

>990_bases
ATGAGCGCTTATATCATTGAAACCTTGATTAAAATTTTGATTTTAGTCGCTGTTTTTTCGGCTTTAGGAGGCTTTGCCAC
TTATATTGAAAGGAAAGTGTTAGCCTATTTCCAACGCCGTTTAGGGCCTTGTTATGTGGGGCCTTTTGGGCTTTTGCAAG
TCGCAGCAGACGGCATTAAGCTTTTCACCAAAGAAGACATTATCCCCCAAGGCGCTAACAAGTTCATCTTCACGCTAGCA
CCCATTATTGCGATGGTGAGCGCGTTTGTGTCCATGGCACCTATCCCCTTTTTCCCTAATTTCACTCTGTTTGGCTATGA
GATTAAGCCCCTTATTTCTGATATTAACATTGGCTTTTTGTTTTTCTTAGCCGTGGGTGCAGCAGGGATTTATGCACCTA
TTTTAGCCGGGCTTGCTTCTAATAACAAATACTCTTTAATCGGTTCAGCAAGAGCGACGATCCAATTACTCAGCTTTGAA
GTGGTCAGCACCTTAACCATTCTAGCCCCCTTAATGGTGGTAGGATCGCTCTCTTTAGTGGAAATCAATAATTACCAAAG
CGGTGGGTTTTTAGACTGGCTTGTGTTTAAGCAACCACTAGCGTTTGTTTTGTTTTTGATCGCAAGTTATGCTGAATTGA
ATCGCACCCCCTTTGATTTGTTAGAGCATGAAGCCGAGATTGTAGCAGGGTATTGCACCGAATACAGCGGCTTAAAATGG
GGCATGTTCTTTTTAGCGGAATACGCGCATTTATTCGCTTTTTCTTTTGTGATTTCTATCGTGTTTTTTGGCGGGTTTAA
CGCATGGGGCTTCATCCCTGGAGGAATAGCGATTTTGATTAAAGCGGGCTTTTTTGTCTTTTTATCCATGTGGGTTAGAG
CGACTTATCCGCATGTGCGCCCAGACCAACTGATGAATATGTGTTGGAAGATCATGCTGCCTTTAGCGTTATTAAACATT
GTGCTAACAGGCATTATCATTTTAATTTAA

Upstream 100 bases:

>100_bases
TGGATCAAGAGGTGTTTGTTATCTCGCCTTCTCTTTTGAAAAACCATTCTGGCTTTTTTAGAGAGGGCGTGTTTGATAGC
GTGGATTTAAAGGAGCAAGC

Downstream 100 bases:

>100_bases
AGGAGGTTTTATGGCCAAACAAGAATACAAGCAACTTCCTAAACGAGCCGAAGTCCATAGCGCGACCGAGCAATTTAAAG
ACACCATTAAAACGAGCTTG

Product: NADH dehydrogenase subunit H

Products: NA

Alternate protein names: NADH dehydrogenase I subunit H; NDH-1 subunit H [H]

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MSAYIIETLIKILILVAVFSALGGFATYIERKVLAYFQRRLGPCYVGPFGLLQVAADGIKLFTKEDIIPQGANKFIFTLA
PIIAMVSAFVSMAPIPFFPNFTLFGYEIKPLISDINIGFLFFLAVGAAGIYAPILAGLASNNKYSLIGSARATIQLLSFE
VVSTLTILAPLMVVGSLSLVEINNYQSGGFLDWLVFKQPLAFVLFLIASYAELNRTPFDLLEHEAEIVAGYCTEYSGLKW
GMFFLAEYAHLFAFSFVISIVFFGGFNAWGFIPGGIAILIKAGFFVFLSMWVRATYPHVRPDQLMNMCWKIMLPLALLNI
VLTGIIILI

Sequences:

>Translated_329_residues
MSAYIIETLIKILILVAVFSALGGFATYIERKVLAYFQRRLGPCYVGPFGLLQVAADGIKLFTKEDIIPQGANKFIFTLA
PIIAMVSAFVSMAPIPFFPNFTLFGYEIKPLISDINIGFLFFLAVGAAGIYAPILAGLASNNKYSLIGSARATIQLLSFE
VVSTLTILAPLMVVGSLSLVEINNYQSGGFLDWLVFKQPLAFVLFLIASYAELNRTPFDLLEHEAEIVAGYCTEYSGLKW
GMFFLAEYAHLFAFSFVISIVFFGGFNAWGFIPGGIAILIKAGFFVFLSMWVRATYPHVRPDQLMNMCWKIMLPLALLNI
VLTGIIILI
>Mature_328_residues
SAYIIETLIKILILVAVFSALGGFATYIERKVLAYFQRRLGPCYVGPFGLLQVAADGIKLFTKEDIIPQGANKFIFTLAP
IIAMVSAFVSMAPIPFFPNFTLFGYEIKPLISDINIGFLFFLAVGAAGIYAPILAGLASNNKYSLIGSARATIQLLSFEV
VSTLTILAPLMVVGSLSLVEINNYQSGGFLDWLVFKQPLAFVLFLIASYAELNRTPFDLLEHEAEIVAGYCTEYSGLKWG
MFFLAEYAHLFAFSFVISIVFFGGFNAWGFIPGGIAILIKAGFFVFLSMWVRATYPHVRPDQLMNMCWKIMLPLALLNIV
LTGIIILI

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1005

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 1 (chain H)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Homo sapiens, GI251831107, Length=295, Percent_Identity=35.9322033898305, Blast_Score=175, Evalue=5e-44,
Organism=Escherichia coli, GI1788618, Length=324, Percent_Identity=39.8148148148148, Blast_Score=226, Evalue=1e-60,
Organism=Escherichia coli, GI87082115, Length=227, Percent_Identity=28.1938325991189, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1789077, Length=281, Percent_Identity=28.1138790035587, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 36306; Mature: 36175

Theoretical pI: Translated: 7.43; Mature: 7.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAYIIETLIKILILVAVFSALGGFATYIERKVLAYFQRRLGPCYVGPFGLLQVAADGIK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
LFTKEDIIPQGANKFIFTLAPIIAMVSAFVSMAPIPFFPNFTLFGYEIKPLISDINIGFL
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECEEHHHHHHHCHHHHH
FFLAVGAAGIYAPILAGLASNNKYSLIGSARATIQLLSFEVVSTLTILAPLMVVGSLSLV
HHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
EINNYQSGGFLDWLVFKQPLAFVLFLIASYAELNRTPFDLLEHEAEIVAGYCTEYSGLKW
EECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHH
GMFFLAEYAHLFAFSFVISIVFFGGFNAWGFIPGGIAILIKAGFFVFLSMWVRATYPHVR
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
PDQLMNMCWKIMLPLALLNIVLTGIIILI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
SAYIIETLIKILILVAVFSALGGFATYIERKVLAYFQRRLGPCYVGPFGLLQVAADGIK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
LFTKEDIIPQGANKFIFTLAPIIAMVSAFVSMAPIPFFPNFTLFGYEIKPLISDINIGFL
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECEEHHHHHHHCHHHHH
FFLAVGAAGIYAPILAGLASNNKYSLIGSARATIQLLSFEVVSTLTILAPLMVVGSLSLV
HHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
EINNYQSGGFLDWLVFKQPLAFVLFLIASYAELNRTPFDLLEHEAEIVAGYCTEYSGLKW
EECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHH
GMFFLAEYAHLFAFSFVISIVFFGGFNAWGFIPGGIAILIKAGFFVFLSMWVRATYPHVR
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
PDQLMNMCWKIMLPLALLNIVLTGIIILI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA