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The map label for this gene is nuoG2 [H]

Identifier: 188528055

GI number: 188528055

Start: 1287520

End: 1290054

Strand: Direct

Name: nuoG2 [H]

Synonym: HPSH_06560

Alternate gene names: 188528055

Gene position: 1287520-1290054 (Clockwise)

Preceding gene: 188528054

Following gene: 188528056

Centisome position: 80.04

GC content: 41.7

Gene sequence:

>2535_bases
ATGATCACAATAAATATCAATGGCAAAATGATTGAATGCCAAGAGGGACAAAGCGTTTTAGAGGCTGCCAGGAGCGCTGG
GATCTACATCCCTACTATTTGCTATTTAAGCGGTTGCTCGCCCACAGTCGCATGCAAAATGTGCATGGTTGAAATGGATG
GCAAACGGGTTTATAGTTGCAACACGAAAGCCAAAAACAACGCCGTTATCCTCACCAACACCCCAACGCTCATGGATGAA
AGAAAAAGCATCATGCAAACTTATGATGTCAATCACCCCCTAGAGTGTGGCGTGTGCGATAAGAGCGGGGAGTGCGAATT
GCAAGACATGACGCATTTAACCGGCGTAGAGCACCAACCTTATGCGGTGGCTGATGATTTTAAAGCGCTAGATTCATGGG
CACAAGCCTTGTATGATCCCAATTTGTGCATCATGTGCGAAAGGTGCGTAACCACTTGCAAGGACAATGTGGGCGAAGAC
AACCTCAAAGCCACTAAAGCCAATTTGCATGCTCCAGATAAATTTAAAGACCGCATGTCCAAAGACGCTTTTAGCGTGTG
GAGTCGTAAGCAAAAAGGCATTATTTCTTTTGTGGGTAGCGTGCCTTGTTATGATTGCGGGGAGTGCATTGCGGTATGCC
CTGTGGGCGCTTTGAGTTATAAAGATTTCGCTTACACGGCTAACGCATGGGAATTAAAAAAGATCTATTCTACTTGTTCG
CATTGTTCAGCCGGTTGTTTGATTTCTTATGATGTGCGCCATTTTGATACTCTAGGCGAAGAATCTAAAATTTTTAGAGT
GCTTAATGATTTTTACCATAACCCTATTTGTGGGGCAGGCCGTTTCGCTTTTGATGTGAGCTCTAGCCCTAAAGGCAGCA
CTAATCTTAAAGAAGCGCAAAACGCCCTCAAAGAATGCGAAGCGGTGCGGATAGGAGGAGACATTACGAATGAAGAGGCG
TTTTTAATAGAGCGTTTAAGGAAAAAGCTTGATTTTAAAATCTACAATCAAGAAGCGTATCATTTCCAGCAATTTTTAAA
AGTATTAGGCGAAGTTAAACGCCCTAGTATTGAAGAGATTAAAACTTCTCATTTAGTCATCACGATGGGATCTTCTATCA
AAACAGAAAACCCTTTGGTGCGCTATGCTATCAATAACGCCCTCAAACTCAATAAAGCTTCTTTGATCGCTATGCACCCT
ATCAAGGATAACGCGTTAGCGAATTTGTGCCGAAGCTCTTTTTGCATCACCCATGAAGTGGGGGCTGAAGAAATCCTTTT
GGGCATGCTTTTAAAAATGCTTAACATTGAAAGCGCGGCTCTAAAAAGTTTAGAAGATTCCAAGCAAAGCATTGTAGATG
AAGCGGCTCTTAAAGCCTTAGAAGAAGAGCGAAAAAAAGCTTTAGAACAAGCCGAGCAAGGGTGCAATATTGGAGAAAAT
AAGGCAGAAAATCAAGAAGAGGATAAAACAGAAGCAGCCACCCCAAAAGAAGAAAATCAAGAAAAAAACAAGACAGAGGT
TAGAGAAGAAAGCGTTGAAGTCCCTACCAAAACCACTTATTTGTTGCTTGAAGAAGCGGGCATCAATTTAGAAACTTATG
AAAAAATTCTGGCTCTTTTGCAAAAATCAAATAACACCTTGCTAGTGGTTGGCGAAGAAATCTATAGCCATAAACAAGCC
CACAATATCGCTAAAATGTTGCGTTTGTTAGCCCAAAAAAGCACTATTAAACTCGTTCTTATCCCCCCAAGCGCCAACGC
TTTAGGCATCGCTTCCCTTTGTGAATTGAGCGAAGAAATTTTTGAACATGAAAAAATTGTAGGCATTCGCGCTCAAGGGG
ATTTCACTATCAATAGCGATGATAGGGTTTTTGGAAAAGACGCCGTCAGCAAAGTGGATTTTATTTTACCCAGCCTTAAC
CAGCTAGAGGGCACGATCACTAATATTGAAGGGCGCGTGTTGCCCTTAAAACCGGCTTTGAGGTTTGAAGGCTATGATTT
GAGCGACATTATGCAAGGCTTTGGCTTTGTGGAAGAAAGCCTCACAGAATGCACCCACAAACTCCCTACAGAAGCGGGCT
TTAAAGCTATAGAATTTGACCATCTGACCAACTATTTCACTAACGACAGAGTCAATCACAGAGGCTATCTGCTAGGAACA
AGCCCTTTTGAAAAGAGCGCTAAAGAATACGAAACCACAGAATGCGAGCCTATCAAGCCTTTAAAAGAAAAAATCGCTTT
CAACGCGTATTTAAAATACCCAGAAACGCAATTCAATAACGCTACCAATAAAAGCGAGAATTTGCAATTAAAAGCCGGTG
TCTATGTGTCTAAAGCTTTCTTAAAGAAATTGAATAAAGAAGTGGGGCAAAGCATCACTTTATCTAAAGAAGAAGAGGAA
TTAACAGGCGTTTTGTATCTTGATGAAAGCTTGGATCAAGAGGTGTTTGTTATCTCGCCTTCTCTTTTGAAAAACCATTC
TGGCTTTTTTAGAGAGGGCGTGTTTGATAGCGTGGATTTAAAGGAGCAAGCATGA

Upstream 100 bases:

>100_bases
AAGAAAGCCCCCATTTGAAGGGTTTGATTGCGATTTTAGAAGGGGCGTTTTTTGACGCTTACCCTTATATCCCTATTTTA
TCCCACTCTCAAGGAATTTC

Downstream 100 bases:

>100_bases
GCGCTTATATCATTGAAACCTTGATTAAAATTTTGATTTTAGTCGCTGTTTTTTCGGCTTTAGGAGGCTTTGCCACTTAT
ATTGAAAGGAAAGTGTTAGC

Product: NADH dehydrogenase subunit G

Products: NA

Alternate protein names: NADH dehydrogenase I subunit G 2; NDH-1 subunit G 2 [H]

Number of amino acids: Translated: 844; Mature: 844

Protein sequence:

>844_residues
MITININGKMIECQEGQSVLEAARSAGIYIPTICYLSGCSPTVACKMCMVEMDGKRVYSCNTKAKNNAVILTNTPTLMDE
RKSIMQTYDVNHPLECGVCDKSGECELQDMTHLTGVEHQPYAVADDFKALDSWAQALYDPNLCIMCERCVTTCKDNVGED
NLKATKANLHAPDKFKDRMSKDAFSVWSRKQKGIISFVGSVPCYDCGECIAVCPVGALSYKDFAYTANAWELKKIYSTCS
HCSAGCLISYDVRHFDTLGEESKIFRVLNDFYHNPICGAGRFAFDVSSSPKGSTNLKEAQNALKECEAVRIGGDITNEEA
FLIERLRKKLDFKIYNQEAYHFQQFLKVLGEVKRPSIEEIKTSHLVITMGSSIKTENPLVRYAINNALKLNKASLIAMHP
IKDNALANLCRSSFCITHEVGAEEILLGMLLKMLNIESAALKSLEDSKQSIVDEAALKALEEERKKALEQAEQGCNIGEN
KAENQEEDKTEAATPKEENQEKNKTEVREESVEVPTKTTYLLLEEAGINLETYEKILALLQKSNNTLLVVGEEIYSHKQA
HNIAKMLRLLAQKSTIKLVLIPPSANALGIASLCELSEEIFEHEKIVGIRAQGDFTINSDDRVFGKDAVSKVDFILPSLN
QLEGTITNIEGRVLPLKPALRFEGYDLSDIMQGFGFVEESLTECTHKLPTEAGFKAIEFDHLTNYFTNDRVNHRGYLLGT
SPFEKSAKEYETTECEPIKPLKEKIAFNAYLKYPETQFNNATNKSENLQLKAGVYVSKAFLKKLNKEVGQSITLSKEEEE
LTGVLYLDESLDQEVFVISPSLLKNHSGFFREGVFDSVDLKEQA

Sequences:

>Translated_844_residues
MITININGKMIECQEGQSVLEAARSAGIYIPTICYLSGCSPTVACKMCMVEMDGKRVYSCNTKAKNNAVILTNTPTLMDE
RKSIMQTYDVNHPLECGVCDKSGECELQDMTHLTGVEHQPYAVADDFKALDSWAQALYDPNLCIMCERCVTTCKDNVGED
NLKATKANLHAPDKFKDRMSKDAFSVWSRKQKGIISFVGSVPCYDCGECIAVCPVGALSYKDFAYTANAWELKKIYSTCS
HCSAGCLISYDVRHFDTLGEESKIFRVLNDFYHNPICGAGRFAFDVSSSPKGSTNLKEAQNALKECEAVRIGGDITNEEA
FLIERLRKKLDFKIYNQEAYHFQQFLKVLGEVKRPSIEEIKTSHLVITMGSSIKTENPLVRYAINNALKLNKASLIAMHP
IKDNALANLCRSSFCITHEVGAEEILLGMLLKMLNIESAALKSLEDSKQSIVDEAALKALEEERKKALEQAEQGCNIGEN
KAENQEEDKTEAATPKEENQEKNKTEVREESVEVPTKTTYLLLEEAGINLETYEKILALLQKSNNTLLVVGEEIYSHKQA
HNIAKMLRLLAQKSTIKLVLIPPSANALGIASLCELSEEIFEHEKIVGIRAQGDFTINSDDRVFGKDAVSKVDFILPSLN
QLEGTITNIEGRVLPLKPALRFEGYDLSDIMQGFGFVEESLTECTHKLPTEAGFKAIEFDHLTNYFTNDRVNHRGYLLGT
SPFEKSAKEYETTECEPIKPLKEKIAFNAYLKYPETQFNNATNKSENLQLKAGVYVSKAFLKKLNKEVGQSITLSKEEEE
LTGVLYLDESLDQEVFVISPSLLKNHSGFFREGVFDSVDLKEQA
>Mature_844_residues
MITININGKMIECQEGQSVLEAARSAGIYIPTICYLSGCSPTVACKMCMVEMDGKRVYSCNTKAKNNAVILTNTPTLMDE
RKSIMQTYDVNHPLECGVCDKSGECELQDMTHLTGVEHQPYAVADDFKALDSWAQALYDPNLCIMCERCVTTCKDNVGED
NLKATKANLHAPDKFKDRMSKDAFSVWSRKQKGIISFVGSVPCYDCGECIAVCPVGALSYKDFAYTANAWELKKIYSTCS
HCSAGCLISYDVRHFDTLGEESKIFRVLNDFYHNPICGAGRFAFDVSSSPKGSTNLKEAQNALKECEAVRIGGDITNEEA
FLIERLRKKLDFKIYNQEAYHFQQFLKVLGEVKRPSIEEIKTSHLVITMGSSIKTENPLVRYAINNALKLNKASLIAMHP
IKDNALANLCRSSFCITHEVGAEEILLGMLLKMLNIESAALKSLEDSKQSIVDEAALKALEEERKKALEQAEQGCNIGEN
KAENQEEDKTEAATPKEENQEKNKTEVREESVEVPTKTTYLLLEEAGINLETYEKILALLQKSNNTLLVVGEEIYSHKQA
HNIAKMLRLLAQKSTIKLVLIPPSANALGIASLCELSEEIFEHEKIVGIRAQGDFTINSDDRVFGKDAVSKVDFILPSLN
QLEGTITNIEGRVLPLKPALRFEGYDLSDIMQGFGFVEESLTECTHKLPTEAGFKAIEFDHLTNYFTNDRVNHRGYLLGT
SPFEKSAKEYETTECEPIKPLKEKIAFNAYLKYPETQFNNATNKSENLQLKAGVYVSKAFLKKLNKEVGQSITLSKEEEE
LTGVLYLDESLDQEVFVISPSLLKNHSGFFREGVFDSVDLKEQA

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1034

COG function: function code C; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=294, Percent_Identity=28.9115646258503, Blast_Score=118, Evalue=2e-26,
Organism=Escherichia coli, GI145693161, Length=441, Percent_Identity=24.9433106575964, Blast_Score=122, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI17565758, Length=302, Percent_Identity=28.1456953642384, Blast_Score=103, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI32566231, Length=302, Percent_Identity=28.1456953642384, Blast_Score=102, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI193209088, Length=254, Percent_Identity=28.740157480315, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24640559, Length=248, Percent_Identity=27.4193548387097, Blast_Score=100, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24640557, Length=248, Percent_Identity=27.4193548387097, Blast_Score=100, Evalue=5e-21,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR009010
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR006655
- InterPro:   IPR000283
- InterPro:   IPR019574 [H]

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 94251; Mature: 94251

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITININGKMIECQEGQSVLEAARSAGIYIPTICYLSGCSPTVACKMCMVEMDGKRVYSC
CEEEEECCCEEECCCCHHHHHHHHHCCCEEEHHHEECCCCHHHHHHHHHEEECCCEEEEE
NTKAKNNAVILTNTPTLMDERKSIMQTYDVNHPLECGVCDKSGECELQDMTHLTGVEHQP
CCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCC
YAVADDFKALDSWAQALYDPNLCIMCERCVTTCKDNVGEDNLKATKANLHAPDKFKDRMS
CCHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCCEECCCCCCCCHHHHHHHH
KDAFSVWSRKQKGIISFVGSVPCYDCGECIAVCPVGALSYKDFAYTANAWELKKIYSTCS
HHHHHHHHHHHCCHHHHHCCCCCCCCCCHHHHCCCCCCCCCCCEEECCHHHHHHHHHHHH
HCSAGCLISYDVRHFDTLGEESKIFRVLNDFYHNPICGAGRFAFDVSSSPKGSTNLKEAQ
CCCCCCEEEECHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCHHHHH
NALKECEAVRIGGDITNEEAFLIERLRKKLDFKIYNQEAYHFQQFLKVLGEVKRPSIEEI
HHHHHCCEEEECCCCCCCHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHHCCCCHHHH
KTSHLVITMGSSIKTENPLVRYAINNALKLNKASLIAMHPIKDNALANLCRSSFCITHEV
CCCEEEEEECCCCCCCCCEEEEECCCHHEECCCEEEEECCCCCHHHHHHHHHCCEEEECC
GAEEILLGMLLKMLNIESAALKSLEDSKQSIVDEAALKALEEERKKALEQAEQGCNIGEN
CHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
KAENQEEDKTEAATPKEENQEKNKTEVREESVEVPTKTTYLLLEEAGINLETYEKILALL
CCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHH
QKSNNTLLVVGEEIYSHKQAHNIAKMLRLLAQKSTIKLVLIPPSANALGIASLCELSEEI
HCCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHH
FEHEKIVGIRAQGDFTINSDDRVFGKDAVSKVDFILPSLNQLEGTITNIEGRVLPLKPAL
HHHHHEEEEEECCCEEECCCCCCCCHHHHHHHHHHHCCHHHHCCEEECCCCEEEECCCCC
RFEGYDLSDIMQGFGFVEESLTECTHKLPTEAGFKAIEFDHLTNYFTNDRVNHRGYLLGT
EECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHCCCEEEHHHHHHHHCCCCCCCCEEEEEC
SPFEKSAKEYETTECEPIKPLKEKIAFNAYLKYPETQFNNATNKSENLQLKAGVYVSKAF
CCHHHHHHHCCCCCCCCCHHHHHHHHHHHEECCCCHHCCCCCCCCCCEEEECCHHHHHHH
LKKLNKEVGQSITLSKEEEELTGVLYLDESLDQEVFVISPSLLKNHSGFFREGVFDSVDL
HHHHHHHHCCCEECCCCHHHHEEEEEECCCCCCEEEEECHHHHHCCCCHHHHCCCCCCCC
KEQA
CCCC
>Mature Secondary Structure
MITININGKMIECQEGQSVLEAARSAGIYIPTICYLSGCSPTVACKMCMVEMDGKRVYSC
CEEEEECCCEEECCCCHHHHHHHHHCCCEEEHHHEECCCCHHHHHHHHHEEECCCEEEEE
NTKAKNNAVILTNTPTLMDERKSIMQTYDVNHPLECGVCDKSGECELQDMTHLTGVEHQP
CCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCC
YAVADDFKALDSWAQALYDPNLCIMCERCVTTCKDNVGEDNLKATKANLHAPDKFKDRMS
CCHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCCEECCCCCCCCHHHHHHHH
KDAFSVWSRKQKGIISFVGSVPCYDCGECIAVCPVGALSYKDFAYTANAWELKKIYSTCS
HHHHHHHHHHHCCHHHHHCCCCCCCCCCHHHHCCCCCCCCCCCEEECCHHHHHHHHHHHH
HCSAGCLISYDVRHFDTLGEESKIFRVLNDFYHNPICGAGRFAFDVSSSPKGSTNLKEAQ
CCCCCCEEEECHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCHHHHH
NALKECEAVRIGGDITNEEAFLIERLRKKLDFKIYNQEAYHFQQFLKVLGEVKRPSIEEI
HHHHHCCEEEECCCCCCCHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHHCCCCHHHH
KTSHLVITMGSSIKTENPLVRYAINNALKLNKASLIAMHPIKDNALANLCRSSFCITHEV
CCCEEEEEECCCCCCCCCEEEEECCCHHEECCCEEEEECCCCCHHHHHHHHHCCEEEECC
GAEEILLGMLLKMLNIESAALKSLEDSKQSIVDEAALKALEEERKKALEQAEQGCNIGEN
CHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
KAENQEEDKTEAATPKEENQEKNKTEVREESVEVPTKTTYLLLEEAGINLETYEKILALL
CCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHH
QKSNNTLLVVGEEIYSHKQAHNIAKMLRLLAQKSTIKLVLIPPSANALGIASLCELSEEI
HCCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHH
FEHEKIVGIRAQGDFTINSDDRVFGKDAVSKVDFILPSLNQLEGTITNIEGRVLPLKPAL
HHHHHEEEEEECCCEEECCCCCCCCHHHHHHHHHHHCCHHHHCCEEECCCCEEEECCCCC
RFEGYDLSDIMQGFGFVEESLTECTHKLPTEAGFKAIEFDHLTNYFTNDRVNHRGYLLGT
EECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHCCCEEEHHHHHHHHCCCCCCCCEEEEEC
SPFEKSAKEYETTECEPIKPLKEKIAFNAYLKYPETQFNNATNKSENLQLKAGVYVSKAF
CCHHHHHHHCCCCCCCCCHHHHHHHHHHHEECCCCHHCCCCCCCCCCEEEECCHHHHHHH
LKKLNKEVGQSITLSKEEEELTGVLYLDESLDQEVFVISPSLLKNHSGFFREGVFDSVDL
HHHHHHHHCCCEECCCCHHHHEEEEEECCCCCCEEEEECHHHHHCCCCHHHHCCCCCCCC
KEQA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481432 [H]